CN100570332C - 微片 - Google Patents

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Publication number
CN100570332C
CN100570332C CNB200510106813XA CN200510106813A CN100570332C CN 100570332 C CN100570332 C CN 100570332C CN B200510106813X A CNB200510106813X A CN B200510106813XA CN 200510106813 A CN200510106813 A CN 200510106813A CN 100570332 C CN100570332 C CN 100570332C
Authority
CN
China
Prior art keywords
light
microchip
sample
measurement
reagent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB200510106813XA
Other languages
English (en)
Chinese (zh)
Other versions
CN1752741A (zh
Inventor
松本茂树
野泽繁典
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rohm Co Ltd
Original Assignee
Ushio Denki KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ushio Denki KK filed Critical Ushio Denki KK
Publication of CN1752741A publication Critical patent/CN1752741A/zh
Application granted granted Critical
Publication of CN100570332C publication Critical patent/CN100570332C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0654—Lenses; Optical fibres
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N2021/0325—Cells for testing reactions, e.g. containing reagents
    • G01N2021/0328—Arrangement of two or more cells having different functions for the measurement of reactions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N2021/0346—Capillary cells; Microcells

Landscapes

  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Hematology (AREA)
  • Dispersion Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optical Measuring Cells (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
CNB200510106813XA 2004-09-22 2005-09-22 微片 Expired - Fee Related CN100570332C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2004274673 2004-09-22
JP2004274673A JP4375183B2 (ja) 2004-09-22 2004-09-22 マイクロチップ

Publications (2)

Publication Number Publication Date
CN1752741A CN1752741A (zh) 2006-03-29
CN100570332C true CN100570332C (zh) 2009-12-16

Family

ID=35462319

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB200510106813XA Expired - Fee Related CN100570332C (zh) 2004-09-22 2005-09-22 微片

Country Status (6)

Country Link
US (1) US7981689B2 (2)
EP (1) EP1640703B1 (2)
JP (1) JP4375183B2 (2)
CN (1) CN100570332C (2)
DE (1) DE602005016506D1 (2)
TW (1) TW200610952A (2)

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JP4506375B2 (ja) * 2004-09-22 2010-07-21 ウシオ電機株式会社 吸光度測定ユニット
JP4912096B2 (ja) * 2006-09-07 2012-04-04 ローム株式会社 マイクロチップ検査装置
US20090141282A1 (en) * 2007-12-04 2009-06-04 Yung-Lieh Chien Concentration measuring structure capable of reducing the effect of environmental temperature
WO2010120786A1 (en) 2009-04-13 2010-10-21 Micronics, Inc. Microfluidic clinical analyzer
WO2011094577A2 (en) 2010-01-29 2011-08-04 Micronics, Inc. Sample-to-answer microfluidic cartridge
CN103140755B (zh) 2010-07-22 2016-03-16 哈希公司 用于碱度分析的芯片上实验室
FR2981283B1 (fr) * 2011-10-13 2014-08-29 Chambre De Commerce Et De L Ind De Paris Au Titre De Son Etablissement D Enseignement Superieur Esie Dispositif microfluidique pour analyser un fluide sous pression.
US8741234B2 (en) * 2011-12-27 2014-06-03 Honeywell International Inc. Disposable cartridge for fluid analysis
US9180449B2 (en) 2012-06-12 2015-11-10 Hach Company Mobile water analysis
USD768872S1 (en) 2012-12-12 2016-10-11 Hach Company Cuvette for a water analysis instrument
JP2016509206A (ja) 2012-12-21 2016-03-24 マイクロニクス， インコーポレイテッド 携帯型蛍光検出システムおよびマイクロアッセイカートリッジ
WO2014100732A1 (en) 2012-12-21 2014-06-26 Micronics, Inc. Fluidic circuits and related manufacturing methods
US10518262B2 (en) 2012-12-21 2019-12-31 Perkinelmer Health Sciences, Inc. Low elasticity films for microfluidic use
CN105189784B (zh) 2013-05-07 2020-06-30 珀金埃尔默健康科学有限公司 用于制备和分析核酸的装置
CA2911303C (en) 2013-05-07 2021-02-16 Micronics, Inc. Methods for preparation of nucleic acid-containing samples using clay minerals and alkaline solutions
WO2014182844A1 (en) 2013-05-07 2014-11-13 Micronics, Inc. Microfluidic devices and methods for performing serum separation and blood cross-matching
US10539582B2 (en) 2014-06-30 2020-01-21 Phc Holdings Corporation Substrate for sample analysis, sample analysis device, sample analysis system, and method for removing liquid from liquid that contains magnetic particles
US10520521B2 (en) 2014-06-30 2019-12-31 Phc Holdings Corporation Substrate for sample analysis, sample analysis device, sample analysis system, and program for sample analysis system
WO2016002731A1 (ja) 2014-06-30 2016-01-07 パナソニックヘルスケアホールディングス株式会社 試料分析用基板および試料分析装置
US10309976B2 (en) 2014-06-30 2019-06-04 Phc Holdings Corporation Substrate for sample analysis, sample analysis device, sample analysis system, and program for sample analysis system
WO2016093332A1 (ja) 2014-12-12 2016-06-16 パナソニックヘルスケアホールディングス株式会社 試料分析用基板、試料分析装置、試料分析システムおよび試料分析システム用プログラム
KR20180080396A (ko) * 2017-01-02 2018-07-12 한국전자통신연구원 바이오 센서
WO2022155142A1 (en) * 2021-01-12 2022-07-21 Repligen Corporation Offline and inline determination of concentration of metabolites in cell culture fluid

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SE399768B (sv) * 1975-09-29 1978-02-27 Lilja Jan E Kyvett for provtagning, blandning av, provet med ett reagensmedel och direkt utforande av, serskilt optisk, analys av det med reagensmedlet blandade provet
US4226531A (en) * 1977-08-29 1980-10-07 Instrumentation Laboratory Inc. Disposable multi-cuvette rotor
US5798215A (en) * 1993-02-18 1998-08-25 Biocircuits Corporation Device for use in analyte detection assays
US6046840A (en) * 1995-06-19 2000-04-04 Reflectivity, Inc. Double substrate reflective spatial light modulator with self-limiting micro-mechanical elements
US6088102A (en) * 1997-10-31 2000-07-11 Silicon Light Machines Display apparatus including grating light-valve array and interferometric optical system
CA2320296A1 (en) * 1998-05-18 1999-11-25 University Of Washington Liquid analysis cartridge
US6188519B1 (en) * 1999-01-05 2001-02-13 Kenneth Carlisle Johnson Bigrating light valve
EP1247248A4 (en) * 1999-12-14 2010-03-03 Comb Specialists Inc DETECTION SYSTEM FOR DETECTING AND MONITORING / CONTROLLING DEPOSITION ON SUSPENDED TUBES IN RECOVERY AND POWER GENERATION BOILERS
US20030152927A1 (en) * 2000-10-25 2003-08-14 Jakobsen Mogens Havsteen Closed substrate platforms suitable for analysis of biomolecules
JP3760810B2 (ja) * 2001-07-06 2006-03-29 ソニー株式会社 光変調素子、ｇｌｖデバイス、及びレーザディスプレイ
JP2003279471A (ja) 2002-03-20 2003-10-02 Nippon Sheet Glass Co Ltd マイクロ化学システム用チップ及びマイクロ化学システム
US6768555B2 (en) * 2002-03-21 2004-07-27 Industrial Technology Research Institute Fabry-Perot filter apparatus with enhanced optical discrimination
JP2004077305A (ja) * 2002-08-19 2004-03-11 Nec Corp 検出装置
JP2004109099A (ja) * 2002-09-16 2004-04-08 Jun Kikuchi 血液分析方法、血液分析装置および血液分析装置の製造方法
JP4057871B2 (ja) * 2002-09-19 2008-03-05 東芝松下ディスプレイテクノロジー株式会社 液晶表示装置
US6822780B1 (en) * 2003-06-23 2004-11-23 Northrop Grumman Corporation Vertically stacked spatial light modulator with multi-bit phase resolution
US7691328B2 (en) * 2003-10-03 2010-04-06 National Institute For Materials Science Chip using method and test chip
US7710632B2 (en) * 2004-09-27 2010-05-04 Qualcomm Mems Technologies, Inc. Display device having an array of spatial light modulators with integrated color filters

Also Published As

Publication number Publication date
US7981689B2 (en) 2011-07-19
TWI343994B (2) 2011-06-21
JP4375183B2 (ja) 2009-12-02
EP1640703A3 (en) 2006-06-07
DE602005016506D1 (de) 2009-10-22
JP2006090774A (ja) 2006-04-06
EP1640703A2 (en) 2006-03-29
EP1640703B1 (en) 2009-09-09
TW200610952A (en) 2006-04-01
CN1752741A (zh) 2006-03-29
US20060061760A1 (en) 2006-03-23

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
ASS Succession or assignment of patent right

Owner name: ROHM CO., LTD.

Free format text: FORMER OWNER: USHIO DENKI KABUSHIKI KAISHA

Effective date: 20110609

C41 Transfer of patent application or patent right or utility model
COR Change of bibliographic data

Free format text: CORRECT: ADDRESS; FROM: TOKYO METROPOLITAN, STATE OF JAPAN TO: KYOTO, JAPAN

TR01 Transfer of patent right

Effective date of registration: 20110609

Address after: Kyoto Japan

Patentee after: Rohm Co., Ltd.

Address before: Tokyo, Japan

Patentee before: Ushio Denki Kabushiki Kaisha

C17 Cessation of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20091216

Termination date: 20130922