CN101432026A - 通过抑制利于软骨形成的分子来治疗肌腱病变 - Google Patents

通过抑制利于软骨形成的分子来治疗肌腱病变 Download PDF

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Publication number
CN101432026A
CN101432026A CNA2007800156766A CN200780015676A CN101432026A CN 101432026 A CN101432026 A CN 101432026A CN A2007800156766 A CNA2007800156766 A CN A2007800156766A CN 200780015676 A CN200780015676 A CN 200780015676A CN 101432026 A CN101432026 A CN 101432026A
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CN
China
Prior art keywords
tendon
galnact
activity
expression
cartilage
Prior art date
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Pending
Application number
CNA2007800156766A
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English (en)
Chinese (zh)
Inventor
J·M·阿查姆褒特
S·叶林斯基
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Wyeth LLC
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Wyeth LLC
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Application filed by Wyeth LLC filed Critical Wyeth LLC
Publication of CN101432026A publication Critical patent/CN101432026A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CNA2007800156766A 2006-03-03 2007-03-02 通过抑制利于软骨形成的分子来治疗肌腱病变 Pending CN101432026A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77916506P 2006-03-03 2006-03-03
US60/779,165 2006-03-03

Publications (1)

Publication Number Publication Date
CN101432026A true CN101432026A (zh) 2009-05-13

Family

ID=38190750

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2007800156766A Pending CN101432026A (zh) 2006-03-03 2007-03-02 通过抑制利于软骨形成的分子来治疗肌腱病变

Country Status (8)

Country Link
EP (1) EP1991276A2 (fr)
JP (1) JP2009533321A (fr)
CN (1) CN101432026A (fr)
AU (1) AU2007223383A1 (fr)
BR (1) BRPI0708527A2 (fr)
CA (1) CA2644708A1 (fr)
MX (1) MX2008011138A (fr)
WO (1) WO2007103787A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2217249A4 (fr) * 2007-11-06 2011-10-12 Benaroya Res Inst Inhibition de versicane par de l'arnsi et autres molécules
DK3169334T3 (da) 2014-07-16 2021-07-05 Ethris Gmbh Rna til anvendelse til behandling af ledbånds- eller senelæsioner
WO2018180005A1 (fr) * 2017-03-31 2018-10-04 国立研究開発法人日本医療研究開発機構 Acide nucléique antisens pour l'inhibition de la biosynthèse de sulfate de chondroïtine
RU2757081C1 (ru) * 2020-09-21 2021-10-11 Федеральное государственное бюджетное образовательное учреждение высшего образования "Московская государственная академия ветеринарной медицины и биотехнологии - МВА имени К.И. Скрябина" (ФГБОУ ВО МГАВМиБ - МВА имени К.И. Скрябина) Способ стимуляции репаративной регенерации при тендопатиях

Also Published As

Publication number Publication date
EP1991276A2 (fr) 2008-11-19
WO2007103787A2 (fr) 2007-09-13
WO2007103787A3 (fr) 2007-11-15
JP2009533321A (ja) 2009-09-17
AU2007223383A1 (en) 2007-09-13
BRPI0708527A2 (pt) 2011-05-31
MX2008011138A (es) 2008-09-08
CA2644708A1 (fr) 2007-09-13

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Open date: 20090513