CN103289908B - 发酵阿拉伯糖的真核细胞的代谢工程改造 - Google Patents

发酵阿拉伯糖的真核细胞的代谢工程改造 Download PDF

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Publication number
CN103289908B
CN103289908B CN201210316338.9A CN201210316338A CN103289908B CN 103289908 B CN103289908 B CN 103289908B CN 201210316338 A CN201210316338 A CN 201210316338A CN 103289908 B CN103289908 B CN 103289908B
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nucleotide sequence
arabinose
cell
xylose
encoding
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Chinese (zh)
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CN103289908A (zh
Inventor
安东尼斯·杰若恩·阿迪瑞安·马里斯·范
雅各布斯·托马斯·普若克
汉迪瑞克·乌特尔·威塞林克
强汉斯·皮埃特·范迪肯
亚伦·阿迪瑞安·文科勒
强汉斯·汉迪瑞克·温迪·德
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DSM IP Assets BV
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DSM IP Assets BV
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C12P7/08—Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate
    • C12P7/10—Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate substrate containing cellulosic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/01—Phosphotransferases with an alcohol group as acceptor (2.7.1)
    • C12Y207/01016—Ribulokinase (2.7.1.16)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y501/00—Racemaces and epimerases (5.1)
    • C12Y501/03—Racemaces and epimerases (5.1) acting on carbohydrates and derivatives (5.1.3)
    • C12Y501/03004—L-Ribulose-5-phosphate 4-epimerase (5.1.3.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y503/00—Intramolecular oxidoreductases (5.3)
    • C12Y503/01—Intramolecular oxidoreductases (5.3) interconverting aldoses and ketoses (5.3.1)
    • C12Y503/01003—Arabinose isomerase (5.3.1.3)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CN201210316338.9A 2006-10-02 2007-10-01 发酵阿拉伯糖的真核细胞的代谢工程改造 Active CN103289908B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US84835706P 2006-10-02 2006-10-02
EP06121633.9 2006-10-02
EP06121633 2006-10-02
US60/848,357 2006-10-02
CN200780036866.6A CN101522886B (zh) 2006-10-02 2007-10-01 发酵阿拉伯糖的真核细胞的代谢工程改造

Related Parent Applications (1)

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CN200780036866.6A Division CN101522886B (zh) 2006-10-02 2007-10-01 发酵阿拉伯糖的真核细胞的代谢工程改造

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CN103289908A CN103289908A (zh) 2013-09-11
CN103289908B true CN103289908B (zh) 2018-05-11

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CN201210316338.9A Active CN103289908B (zh) 2006-10-02 2007-10-01 发酵阿拉伯糖的真核细胞的代谢工程改造
CN200780036866.6A Expired - Fee Related CN101522886B (zh) 2006-10-02 2007-10-01 发酵阿拉伯糖的真核细胞的代谢工程改造

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Country Status (5)

Country Link
CN (2) CN103289908B (da)
BR (1) BRPI0719262B1 (da)
DK (1) DK2069476T3 (da)
ES (1) ES2601052T3 (da)
PL (1) PL2069476T3 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR081827A1 (es) * 2010-04-21 2012-10-24 Dsm Ip Assets Bv Proceso para producir celulas capaces de convertir arabinosa
CN103555646B (zh) * 2013-10-29 2016-08-31 南京工业大学 一种共表达l-阿拉伯糖异构酶基因和甘露糖-6-磷酸异构酶的基因工程菌
MY188314A (en) * 2014-12-19 2021-11-28 Dsm Ip Assets Bv Fermentation process with improved glycerol and acetic acid conversion
CN109609540B (zh) * 2018-12-27 2022-02-18 吉林中粮生化有限公司 重组酿酒酵母菌株及其制备方法和应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006009434A1 (en) * 2004-07-16 2006-01-26 Technische Universiteit Delft Metabolic engineering of xylose fermenting eukaryotic cells

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006009434A1 (en) * 2004-07-16 2006-01-26 Technische Universiteit Delft Metabolic engineering of xylose fermenting eukaryotic cells

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
A Modified Saccharomyces cerevisiae Strain That Consumes L-Arabinose and Produces Ethanol;Jessica Becker et al;《APPLIED AND ENVIRONMENTAL MICROBIOLOGY》;20030731;第69卷(第7期);4144–4150 *
Complete genome sequence of Lactobacillus plantarum WCFS1;Michiel Kleerebezem et al;《PNAS》;20030218;第100卷(第4期);1990–1995 *
Expression of E. coli araBAD operon encoding enzymes for metabolizing L-arabinose in Saccharomyces cerevisiae;Miroslav Sedlak et al;《Enzyme and Microbial Technology》;20011231;第28卷;16–24 *

Also Published As

Publication number Publication date
CN103289908A (zh) 2013-09-11
CN101522886B (zh) 2015-05-13
BRPI0719262A2 (pt) 2014-03-25
DK2069476T3 (da) 2016-11-28
CN101522886A (zh) 2009-09-02
PL2069476T3 (pl) 2017-02-28
ES2601052T3 (es) 2017-02-14
BRPI0719262B1 (pt) 2017-09-12

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