CN1057834A - 用于治疗与白三烯有关的疾病的酰胺连接的吡啶-苯甲酸衍生物 - Google Patents

用于治疗与白三烯有关的疾病的酰胺连接的吡啶-苯甲酸衍生物 Download PDF

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Publication number
CN1057834A
CN1057834A CN91104852A CN91104852A CN1057834A CN 1057834 A CN1057834 A CN 1057834A CN 91104852 A CN91104852 A CN 91104852A CN 91104852 A CN91104852 A CN 91104852A CN 1057834 A CN1057834 A CN 1057834A
Authority
CN
China
Prior art keywords
compound
aliphatic
pharmaceutically acceptable
group
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN91104852A
Other languages
English (en)
Chinese (zh)
Inventor
R·A·戴恩斯
W·D·金斯伯里
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of CN1057834A publication Critical patent/CN1057834A/zh
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN91104852A 1990-06-07 1991-06-07 用于治疗与白三烯有关的疾病的酰胺连接的吡啶-苯甲酸衍生物 Pending CN1057834A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53438790A 1990-06-07 1990-06-07
US534,387 1990-06-07

Publications (1)

Publication Number Publication Date
CN1057834A true CN1057834A (zh) 1992-01-15

Family

ID=24129827

Family Applications (1)

Application Number Title Priority Date Filing Date
CN91104852A Pending CN1057834A (zh) 1990-06-07 1991-06-07 用于治疗与白三烯有关的疾病的酰胺连接的吡啶-苯甲酸衍生物

Country Status (14)

Country Link
EP (1) EP0532621A1 (fr)
JP (1) JPH05507698A (fr)
KR (1) KR930700448A (fr)
CN (1) CN1057834A (fr)
AU (1) AU7982591A (fr)
CA (1) CA2083956A1 (fr)
FI (1) FI925546L (fr)
HU (1) HUT64521A (fr)
IE (1) IE911938A1 (fr)
IL (1) IL98412A0 (fr)
MA (1) MA22197A1 (fr)
PT (1) PT97911A (fr)
WO (1) WO1991018883A1 (fr)
ZA (1) ZA914369B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102060758A (zh) * 2010-12-21 2011-05-18 杭州师范大学 一种4-苄氧基-吡啶-2-酮的制备方法

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ254473A (en) 1992-06-30 1996-11-26 Smithkline Beecham Corp Preparation of phenylthiomethylpyridinylalkenoates
DE4224402A1 (de) * 1992-07-21 1994-01-27 Schering Ag Neue Pyridin-Derivate mit Leukotrien-B¶4¶-antagonistischer Wirkung
ES2065234B1 (es) * 1992-10-27 1995-09-01 Smithkline Beecham Corp Compuestos para tratar enfermedades relacionadas con los leucotrienos.
JP2001501202A (ja) 1996-09-26 2001-01-30 ノバルティス アクチエンゲゼルシャフト ロイコトリエンｂ４（ｌｔｂ―４）レセプターアンタゴニスト活性によるアリル置換アクリルアミド
PL2520654T3 (pl) 2003-08-26 2017-08-31 The Regents Of The University Of Colorado, A Body Corporate Inhibitory aktywności proteazy serynowej i ich zastosowanie w sposobach i kompozycjach do leczenia zakażeń bakteryjnych

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4555520A (en) * 1984-08-20 1985-11-26 E. R. Squibb & Sons, Inc. 2-Pyridylcarboxamides which inhibit arachidonic acid release

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102060758A (zh) * 2010-12-21 2011-05-18 杭州师范大学 一种4-苄氧基-吡啶-2-酮的制备方法
CN102060758B (zh) * 2010-12-21 2012-12-05 杭州师范大学 一种4-苄氧基-吡啶-2-酮的制备方法

Also Published As

Publication number Publication date
CA2083956A1 (fr) 1991-12-08
EP0532621A1 (fr) 1993-03-24
JPH05507698A (ja) 1993-11-04
HUT64521A (en) 1994-01-28
IE911938A1 (en) 1991-12-18
KR930700448A (ko) 1993-03-15
WO1991018883A1 (fr) 1991-12-12
HU9203868D0 (en) 1993-03-29
PT97911A (pt) 1992-03-31
FI925546A7 (fi) 1992-12-07
FI925546A0 (fi) 1992-12-07
MA22197A1 (fr) 1992-04-01
IL98412A0 (en) 1992-07-15
ZA914369B (en) 1992-06-24
AU7982591A (en) 1991-12-31
FI925546L (fi) 1992-12-07

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C06 Publication
PB01 Publication
C01 Deemed withdrawal of patent application (patent law 1993)
WD01 Invention patent application deemed withdrawn after publication