JPH05507698A - ロイコトリエン関連疾患治療用アミド結合ピリジル―安息香酸誘導体 - Google Patents

ロイコトリエン関連疾患治療用アミド結合ピリジル―安息香酸誘導体

Info

Publication number
JPH05507698A
JPH05507698A JP91510669A JP51066991A JPH05507698A JP H05507698 A JPH05507698 A JP H05507698A JP 91510669 A JP91510669 A JP 91510669A JP 51066991 A JP51066991 A JP 51066991A JP H05507698 A JPH05507698 A JP H05507698A
Authority
JP
Japan
Prior art keywords
pharmaceutically acceptable
aliphatic group
group
pyridyl
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP91510669A
Other languages
English (en)
Japanese (ja)
Inventor
デイニーズ，ロバート・エイ
キングスベリー，ウイリアム・デニス
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of JPH05507698A publication Critical patent/JPH05507698A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP91510669A 1990-06-07 1991-06-05 ロイコトリエン関連疾患治療用アミド結合ピリジル―安息香酸誘導体 Pending JPH05507698A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US53438790A 1990-06-07 1990-06-07
US534,387 1990-06-07
PCT/US1991/003940 WO1991018883A1 (fr) 1990-06-07 1991-06-05 Derives d'acide pyridyle-benzoique a liaison amide utilises dans le traitement de maladies associees aux leucotrienes

Publications (1)

Publication Number Publication Date
JPH05507698A true JPH05507698A (ja) 1993-11-04

Family

ID=24129827

Family Applications (1)

Application Number Title Priority Date Filing Date
JP91510669A Pending JPH05507698A (ja) 1990-06-07 1991-06-05 ロイコトリエン関連疾患治療用アミド結合ピリジル―安息香酸誘導体

Country Status (14)

Country Link
EP (1) EP0532621A1 (fr)
JP (1) JPH05507698A (fr)
KR (1) KR930700448A (fr)
CN (1) CN1057834A (fr)
AU (1) AU7982591A (fr)
CA (1) CA2083956A1 (fr)
FI (1) FI925546L (fr)
HU (1) HUT64521A (fr)
IE (1) IE911938A1 (fr)
IL (1) IL98412A0 (fr)
MA (1) MA22197A1 (fr)
PT (1) PT97911A (fr)
WO (1) WO1991018883A1 (fr)
ZA (1) ZA914369B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ254473A (en) 1992-06-30 1996-11-26 Smithkline Beecham Corp Preparation of phenylthiomethylpyridinylalkenoates
DE4224402A1 (de) * 1992-07-21 1994-01-27 Schering Ag Neue Pyridin-Derivate mit Leukotrien-B¶4¶-antagonistischer Wirkung
ES2065234B1 (es) * 1992-10-27 1995-09-01 Smithkline Beecham Corp Compuestos para tratar enfermedades relacionadas con los leucotrienos.
JP2001501202A (ja) 1996-09-26 2001-01-30 ノバルティス アクチエンゲゼルシャフト ロイコトリエンｂ４（ｌｔｂ―４）レセプターアンタゴニスト活性によるアリル置換アクリルアミド
PL2520654T3 (pl) 2003-08-26 2017-08-31 The Regents Of The University Of Colorado, A Body Corporate Inhibitory aktywności proteazy serynowej i ich zastosowanie w sposobach i kompozycjach do leczenia zakażeń bakteryjnych
CN102060758B (zh) * 2010-12-21 2012-12-05 杭州师范大学 一种4-苄氧基-吡啶-2-酮的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4555520A (en) * 1984-08-20 1985-11-26 E. R. Squibb & Sons, Inc. 2-Pyridylcarboxamides which inhibit arachidonic acid release

Also Published As

Publication number Publication date
CA2083956A1 (fr) 1991-12-08
EP0532621A1 (fr) 1993-03-24
CN1057834A (zh) 1992-01-15
HUT64521A (en) 1994-01-28
IE911938A1 (en) 1991-12-18
KR930700448A (ko) 1993-03-15
WO1991018883A1 (fr) 1991-12-12
HU9203868D0 (en) 1993-03-29
PT97911A (pt) 1992-03-31
FI925546A7 (fi) 1992-12-07
FI925546A0 (fi) 1992-12-07
MA22197A1 (fr) 1992-04-01
IL98412A0 (en) 1992-07-15
ZA914369B (en) 1992-06-24
AU7982591A (en) 1991-12-31
FI925546L (fi) 1992-12-07

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