CN1064268A - 制备含有喹啉盐的药物组合物的方法 - Google Patents

制备含有喹啉盐的药物组合物的方法 Download PDF

Info

Publication number
CN1064268A
CN1064268A CN92101029A CN92101029A CN1064268A CN 1064268 A CN1064268 A CN 1064268A CN 92101029 A CN92101029 A CN 92101029A CN 92101029 A CN92101029 A CN 92101029A CN 1064268 A CN1064268 A CN 1064268A
Authority
CN
China
Prior art keywords
salt
quinolinium
strong acid
salts
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN92101029A
Other languages
English (en)
Chinese (zh)
Inventor
R·J·艾夫
C·A·利奇
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Smithkl Ine Beecham
SmithKline Beecham Corp
Original Assignee
Smithkl Ine Beecham
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB919101918A external-priority patent/GB9101918D0/en
Priority claimed from GB919101919A external-priority patent/GB9101919D0/en
Application filed by Smithkl Ine Beecham filed Critical Smithkl Ine Beecham
Publication of CN1064268A publication Critical patent/CN1064268A/zh
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • C07D215/44—Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Quinoline Compounds (AREA)
CN92101029A 1991-01-29 1992-01-28 制备含有喹啉盐的药物组合物的方法 Pending CN1064268A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB919101918A GB9101918D0 (en) 1991-01-29 1991-01-29 Compound
GB9101918.2 1991-01-29
GB9101919.0 1991-01-29
GB919101919A GB9101919D0 (en) 1991-01-29 1991-01-29 Compound

Publications (1)

Publication Number Publication Date
CN1064268A true CN1064268A (zh) 1992-09-09

Family

ID=26298350

Family Applications (1)

Application Number Title Priority Date Filing Date
CN92101029A Pending CN1064268A (zh) 1991-01-29 1992-01-28 制备含有喹啉盐的药物组合物的方法

Country Status (18)

Country Link
EP (1) EP0569396A1 (fr)
JP (1) JPH06504541A (fr)
CN (1) CN1064268A (fr)
AP (1) AP337A (fr)
AU (1) AU652028B2 (fr)
CA (1) CA2099117A1 (fr)
CZ (1) CZ153293A3 (fr)
FI (1) FI933376A0 (fr)
HU (1) HUT67609A (fr)
IE (1) IE920267A1 (fr)
IL (1) IL100791A0 (fr)
MA (1) MA22401A1 (fr)
MX (1) MX9200338A (fr)
NO (1) NO932722L (fr)
NZ (1) NZ241408A (fr)
PT (1) PT100056A (fr)
SK (1) SK70993A3 (fr)
WO (1) WO1992012969A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9126438D0 (en) * 1991-12-12 1992-02-12 Smithkline Beecham Intercredit New quinoline derivatives
US5556863A (en) * 1993-06-11 1996-09-17 Astra Aktiebolag Compound for gastric acid secretion inhibition
IS4164A (is) * 1993-06-11 1994-12-12 Ab Astra Efnasambönd sem hindra flæði magasýru
USRE43932E1 (en) 1997-07-18 2013-01-15 Novartis Ag Crystal modification of a N-phenyl-2-pyrimidineamine derivative, processes for its manufacture and its use
US6852739B1 (en) 1999-02-26 2005-02-08 Nitromed Inc. Methods using proton pump inhibitors and nitric oxide donors
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
CA2467652A1 (fr) * 2001-11-19 2003-05-30 Altana Pharma Ag Agents utiles pour le traitement des troubles des voies aeriennes
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
JP4634144B2 (ja) 2002-08-01 2011-02-16 ニコックス エスエー ニトロソ化プロトンポンプ阻害剤、組成物および使用方法
EP1974730A1 (fr) 2003-11-03 2008-10-01 AstraZeneca AB Dérivés d'imidazo[1,2-a]pyridine pour l'utilisation dans le traitement des troubles du sommeil provoqués par un reflux gastro-oesophagien silencieux

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8804444D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds

Also Published As

Publication number Publication date
FI933376L (fi) 1993-07-28
JPH06504541A (ja) 1994-05-26
FI933376A7 (fi) 1993-07-28
FI933376A0 (fi) 1993-07-28
IL100791A0 (en) 1992-09-06
AP337A (en) 1994-04-08
NO932722D0 (no) 1993-07-28
AU652028B2 (en) 1994-08-11
PT100056A (pt) 1993-03-31
MA22401A1 (fr) 1992-10-01
MX9200338A (es) 1992-12-01
CA2099117A1 (fr) 1992-07-30
NO932722L (no) 1993-07-28
SK70993A3 (en) 1994-01-12
AU1179992A (en) 1992-08-27
NZ241408A (en) 1994-05-26
IE920267A1 (en) 1992-07-29
EP0569396A1 (fr) 1993-11-18
HU9302201D0 (en) 1993-10-28
CZ153293A3 (en) 1993-12-15
HUT67609A (en) 1995-04-28
AP9200352A0 (en) 1992-01-31
WO1992012969A1 (fr) 1992-08-06

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C01 Deemed withdrawal of patent application (patent law 1993)
WD01 Invention patent application deemed withdrawn after publication