CN107308024A - 鼠尾草精油口腔护理凝胶及制备方法 - Google Patents
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Abstract
本发明属于口腔护理凝胶，鼠尾草精油口腔护理凝胶及其制备方法。现有技术使用牙膏在刷牙时进行口腔护理，缺点是：作用时间短，护理效果不理想。本发明由下列重量比物质组成:葡萄糖酸洗必泰0.01～0.012重量份，鼠尾草精油0.85～0.9重量份，没药精油0.1～0.15重量份，薄荷精油0.1～0.15重量份，咪唑啉1～3重量份，甘油4～7重量份，聚氧乙烯聚氧丙烯醚1～3重量份，山梨醇1～2重量份，卡波姆0.5～0.8重量份，去离子水加至100重量份。本发明优点是:口腔护理时间长,抑制口腔有害微生物效果好；抑制口腔微生物繁殖，减少口腔感染发生；镇痛、调节患者情绪；应用广泛。
Description
技术领域
本发明属于口腔护理凝胶，具体地涉及一种鼠尾草精油口腔护理凝胶及其制备方法。
背景技术
口腔健康流行病学临床调查结果我国成年人牙龈出血的发生率为77.3％，牙石检出率97.3％，龋齿发生率88.1％，牙周健康率仅为14.5％。口腔健康问题普遍严重,光靠普通刷牙来保护口腔健康、预防口腔疾病，远远不够。口腔微生物存在于牙菌斑、口腔黏膜、牙结石、龈袋、唾液、术后的牙髓中，特别是牙菌斑具有独特的“生物膜”结构，是造成口腔严重疾患的隐忧。植物精油是从植物中萃取的特有芳香物质，精油中含有的多种物质具有促进粘膜细胞新陈代谢，促进唾液腺分泌，激发自身免疫功能，抑制口腔有害微生物繁殖的作用。洗必泰是一种广谱抗生素，它能与唾液糖蛋白结合，使牙面吸附蛋白减少，干扰菌斑形成。洗必泰还可与细菌细胞外多糖结合，使细菌不易吸附到获得膜上，达到预防和减少牙周病和龋病的目的。现有技术使用牙膏在刷牙时进行口腔护理，缺点是：作用时间短，效果不理想。
凝胶是指颗粒大小在1埃到10埃之间的混合物。高分子溶液在适当的条件下，整个体系会转变成一种弹性的半固体状态的稠厚物质，失去流动性,所形成的产物叫做凝胶。本发明将卡波姆与洗必泰、鼠尾草精油、没药精油等制成口腔护理凝胶,具有抑制口腔有害微生物，提高机体免疫、促进粘膜愈合的功能，改变了原来传统口腔医疗简单杀菌的思维模式，洗必泰可杀灭致病微生物，精油能促进人体益生菌新陈代谢，让益生菌天天生产溶菌酶、生物素去抵御有害菌，从而各司其职形成口腔良性循环，共同创建口腔健康微生态。使用凝胶进行口腔护理，具有作用时间长,抑制口腔有害微生物效果好的优点。本发明使用方便、成本低、口腔预防护理效果好、应用广泛。
发明内容
本发明的目的是提供一种抑制口腔有害微生物繁殖，调整微生态环境、提高免疫功能、促进口腔粘膜愈合的鼠尾草精油口腔护理凝胶。
本发明的另一目的是提供该鼠尾草精油口腔护理凝胶的制备方法。
本发明的目的是这样实现的：
一种鼠尾草精油口腔护理凝胶,由下列重量比物质组成:
一种鼠尾草精油口腔护理凝胶的制备方法,步骤如下:
(1)混合精油制备:按权利要求1所述的重量份准确称鼠尾草、没药精油、薄荷精油，置入同一容器，加入咪唑啉乳化剂1～3重量份，充分搅拌混合，制成乳化精油备用；
(2)分别按权利要求1所述重量份称取葡萄糖酸洗必泰、甘油、聚氧乙烯聚氧丙烯醚、山梨醇、卡波姆置入同一容器，充分搅拌混合；
(3)将步骤(1)产物加入步骤(2)产物中；
(4)向步骤(3)产物加入去离子水，至100重量份；
(5)将步骤(4)产物充分搅拌混合，用均质机二次均质；
(6)将步骤(5)产物抽真空、包装。
本发明的要点是：
将卡波姆与鼠尾草、没药、薄荷混合精油、洗必泰等组合，制备口腔护理凝胶。本发明利用洗必泰与唾液糖蛋白结合，使牙面吸附的蛋白减少；同时与细菌细胞外多糖结合，干扰菌斑的形成并可吸附细菌胞浆膜的渗透屏障，使细胞内容物漏出，低浓度时呈抑菌作用，高浓度时则呈杀菌作用。鼠尾草精油中含有的甙类物质促进人体粘膜细胞新陈代谢，激发粘膜细胞提高自身免疫作用，有效护理口腔；利用没药精油能中和鼠尾草精油的苦味,达到调节凝胶口感，减轻痛感、调节人的情绪。利用薄荷精油清咽润喉、消除口臭。
本发明中的原料卡波姆，中文名称:丙烯酸树脂，分子式:(C3H4O2)n，分子量:72.06。丙烯酸树脂色浅、水白透明；涂膜性能优异，耐光、耐热，耐化学品性及耐腐蚀等性能都极好。本发明中卡波姆起凝结作用，用量极低，以保证使用安全。
本发明中的其它原料，均为现有公知技术，市场公开销售和使用的原料。
本发明的优点是:
1.凝胶剂作用护理时间更长、效果更好,洗必泰抑制口腔有害微生物。
2.多种天然精油配方，充分利用精油小分子高渗透性，给口腔细胞营养，滋润、养护，提高人体自身免疫力，从而调整口腔微生态，抑制口腔微生物繁殖，减少口腔感染发生。
3.具有镇痛、调节患者情绪的作用。
4.应用广泛，除住院和手术人群适用外，长期卧床人群都可使用。
具体实施方式
下面通过具体实施方式对本发明做进一步说明。
实施例1：
(1)混合精油制备:准确称鼠尾草精油0.9公斤、没药精油0.12公斤，薄荷精油0.12公斤，置入同一容器，加入咪唑啉乳化剂1.2公斤，充分搅拌混合，制成乳化精油备用；
(2)分别称取葡萄糖酸洗必泰0.01公斤、甘油4公斤、聚氧乙烯聚氧丙烯醚1.2公斤、山梨醇1公斤、卡波姆0.5公斤置入同一容器，充分搅拌混合；
(3)将乳化精油加入步骤(2)产物中；
(4)向步骤(3)产物加入去离子水，至100公斤；
(5)将步骤(4)产物充分搅拌混合，用均质机二次均质；
(6)将步骤(5)产物抽真空、灌装入袋内。
本发明鼠尾草精油口腔护理凝胶制成。
实施例2：
(1)混合精油制备:准确称鼠尾草精油0.9公斤、没药精油0.15公斤、薄荷精油0.15公斤，置入同一容器，加入咪唑啉乳化剂2公斤，充分搅拌混合，制成乳化精油备用；
(2)分别称取葡萄糖酸洗必泰0.01公斤、甘油5公斤、聚氧乙烯聚氧丙烯醚2公斤、山梨醇1公斤、卡波姆0.8公斤置入同一容器，充分搅拌混合；
(3)将乳化精油加入步骤(2)产物中；
(4)向步骤(3)产物加入去离子水，至100公斤；
(5)将步骤(4)产物充分搅拌混合，用均质机二次均质；
(6)将步骤(5)产物抽真空、灌装入袋内。
本发明鼠尾草精油口腔护理凝胶制成。
实施例3：
口腔溃疡患者，取实施例1制成的凝胶2克，放入口腔溃疡处，每天三次，连续七天，口腔细菌杀灭，溃疡康复。
实施例4：
牙痛患者，取实施例2制成的凝胶2克，放入牙根，1分钟后，牙痛减轻。3分钟后，牙齿不痛。
实施例5：
牙龈出血患者，取实施例2制成的凝胶2克，放入出血患处，1分钟后，疼痛减轻。每天二次，连续三天，牙龈恢复正常。
上述实施例仅为本发明的优选例，并不用来限制本发明，凡在本发明的原则之内，所做的任何修改和变化，均在本发明的保护范围之内。
Claims (2)
1.一种鼠尾草精油口腔护理凝胶,由下列重量比物质组成:
2.一种鼠尾草精油口腔护理凝胶的制备方法,步骤如下:
(1)混合精油制备:按权利要求1所述的重量份准确称鼠尾草、没药精油、薄荷精油，置入同一容器，加入咪唑啉乳化剂1～3重量份，充分搅拌混合，制成乳化精油备用；
(2)分别按权利要求1所述重量份称取葡萄糖酸洗必泰、甘油、聚氧乙烯聚氧丙烯醚、山梨醇、卡波姆置入同一容器，充分搅拌混合；
(3)将步骤(1)产物加入步骤(2)产物中；
(4)向步骤(3)产物加入去离子水，至100重量份；
(5)将步骤(4)产物充分搅拌混合，用均质机二次均质；
(6)将步骤(5)产物抽真空、包装。
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| CN110856702A (zh) * | 2018-08-23 | 2020-03-03 | 上海利康消毒高科技有限公司 | 种植牙口腔护理凝胶及其制备方法 |
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| CN110856702A (zh) * | 2018-08-23 | 2020-03-03 | 上海利康消毒高科技有限公司 | 种植牙口腔护理凝胶及其制备方法 |
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