CN108138182B - 甲状腺素运载蛋白(TTR)iRNA组合物及其治疗或预防TTR相关疾病的使用方法 - Google Patents

甲状腺素运载蛋白(TTR)iRNA组合物及其治疗或预防TTR相关疾病的使用方法 Download PDF

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CN108138182B
CN108138182B CN201680057293.4A CN201680057293A CN108138182B CN 108138182 B CN108138182 B CN 108138182B CN 201680057293 A CN201680057293 A CN 201680057293A CN 108138182 B CN108138182 B CN 108138182B
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nucleotides
ttr
nucleotide
rnai agent
antisense strand
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CN108138182A (zh
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T·齐默尔曼
A·陈
V·贾达夫
M·迈尔
K·G·拉杰夫
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Alnylam Pharmaceuticals Inc
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CN201680057293.4A 2015-07-31 2016-07-28 甲状腺素运载蛋白(TTR)iRNA组合物及其治疗或预防TTR相关疾病的使用方法 Active CN108138182B (zh)

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US201562199563P 2015-07-31 2015-07-31
US62/199,563 2015-07-31
US201662287518P 2016-01-27 2016-01-27
US62/287,518 2016-01-27
PCT/US2016/044359 WO2017023660A1 (en) 2015-07-31 2016-07-28 TRANSTHYRETIN (TTR) iRNA COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATING OR PREVENTING TTR-ASSOCIATED DISEASES

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CN202210881662.9A Pending CN116064515A (zh) 2015-07-31 2016-07-28 甲状腺素运载蛋白（TTR）iRNA组合物及其治疗或预防TTR相关疾病的使用方法

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