DK3719128T3 - Dobbelt-strenget oligonukleotid, sammensætning og konjugat bestaende dobbelt-strenget oligonukleotid, fremgangsmåde herfor og anvendelse heraf - Google Patents

Dobbelt-strenget oligonukleotid, sammensætning og konjugat bestaende dobbelt-strenget oligonukleotid, fremgangsmåde herfor og anvendelse heraf Download PDF

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DK3719128T3
DK3719128T3 DK18884492.2T DK18884492T DK3719128T3 DK 3719128 T3 DK3719128 T3 DK 3719128T3 DK 18884492 T DK18884492 T DK 18884492T DK 3719128 T3 DK3719128 T3 DK 3719128T3
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straindicated
oligonucleotide
double
composition
conjugate consisting
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DK18884492.2T
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Hongyan Zhang
Shan Gao
Daiwu Kang
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Suzhou Ribo Life Science Co Ltd
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    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1131—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
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DK18884492.2T 2017-12-01 2018-11-29 Dobbelt-strenget oligonukleotid, sammensætning og konjugat bestaende dobbelt-strenget oligonukleotid, fremgangsmåde herfor og anvendelse heraf DK3719128T3 (da)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
CN201711249356 2017-12-01
CN201711249333 2017-12-01
CN201711249345 2017-12-01
CN201711479058 2017-12-29
CN201810951752 2018-08-21
CN201811165363 2018-09-30
PCT/CN2018/118212 WO2019105418A1 (zh) 2017-12-01 2018-11-29 双链寡核苷酸、含双链寡核苷酸的组合物与缀合物及制备方法和用途

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DK3719128T3 true DK3719128T3 (da) 2025-03-03

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DK18884492.2T DK3719128T3 (da) 2017-12-01 2018-11-29 Dobbelt-strenget oligonukleotid, sammensætning og konjugat bestaende dobbelt-strenget oligonukleotid, fremgangsmåde herfor og anvendelse heraf

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US (2) US11492620B2 (da)
EP (1) EP3719128B1 (da)
JP (2) JP7727308B2 (da)
KR (1) KR102756073B1 (da)
CN (1) CN110997919B (da)
AU (1) AU2018374219C1 (da)
CA (1) CA3083968C (da)
DK (1) DK3719128T3 (da)
HR (1) HRP20250277T1 (da)
TW (1) TWI791696B (da)
WO (1) WO2019105418A1 (da)

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JP2025512450A (ja) * 2022-04-14 2025-04-17 スーチョウ リボ ライフ サイエンス カンパニー、リミテッド アプタマー、複合体及び組成物並びに製造方法及び使用
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WO2024140101A1 (zh) * 2022-12-28 2024-07-04 北京炫景瑞医药科技有限公司 修饰的双链寡核苷酸分子、修饰的双链寡核苷酸缀合物及其用途
JP2026507087A (ja) * 2023-02-24 2026-02-27 重▲慶▼葯友制葯有限責任公司 ＲおよびＥを含む二本鎖ｓｉＲＮＡアナログおよびそのコンジュゲート
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