CN110317810A - Tmprss6 irna组合物及其使用方法 - Google Patents

Tmprss6 irna组合物及其使用方法 Download PDF

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Publication number
CN110317810A
CN110317810A CN201910593463.6A CN201910593463A CN110317810A CN 110317810 A CN110317810 A CN 110317810A CN 201910593463 A CN201910593463 A CN 201910593463A CN 110317810 A CN110317810 A CN 110317810A
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China
Prior art keywords
nucleotides
double
stranded rnai
strand
rnai agent
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CN201910593463.6A
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Chinese (zh)
Inventor
J·巴特勒
B·贝腾考特
K·G·雷杰夫
M·迈尔
K·查里斯
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Alnylam Pharmaceuticals Inc
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Alnylam Pharmaceuticals Inc
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Publication of CN110317810A publication Critical patent/CN110317810A/zh
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    • C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
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CN201910593463.6A 2013-05-22 2014-05-22 Tmprss6 irna组合物及其使用方法 Pending CN110317810A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361826178P 2013-05-22 2013-05-22
US61/826,178 2013-05-22
US201361912988P 2013-12-06 2013-12-06
US61/912,988 2013-12-06
CN201480040477.0A CN105452463B (zh) 2013-05-22 2014-05-22 Tmprss6 irna组合物及其使用方法

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CN110317810A true CN110317810A (zh) 2019-10-11

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CN201480040477.0A Active CN105452463B (zh) 2013-05-22 2014-05-22 Tmprss6 irna组合物及其使用方法

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Country Link
US (6) US9783806B2 (2)
EP (3) EP2999786A1 (2)
JP (5) JP2016520593A (2)
KR (3) KR102234623B1 (2)
CN (2) CN110317810A (2)
AP (1) AP2015008862A0 (2)
AU (4) AU2014268529C1 (2)
BR (1) BR112015029276B1 (2)
CA (3) CA2912834C (2)
CL (2) CL2015003440A1 (2)
EA (1) EA201592225A1 (2)
HK (1) HK1221978A1 (2)
IL (6) IL324706A (2)
MY (1) MY181888A (2)
RU (1) RU2015154738A (2)
SG (2) SG10202103166XA (2)
TW (3) TW202342750A (2)
UY (1) UY35583A (2)
WO (1) WO2014190157A1 (2)
ZA (1) ZA202110854B (2)

Cited By (1)

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CN117136236A (zh) * 2022-09-29 2023-11-28 广州必贝特医药股份有限公司 用于抑制TMPRSS6基因表达的siRNA或其盐、药物及其应用

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SI3366775T2 (sl) 2011-11-18 2025-12-31 Alnylam Pharmaceuticals, Inc. Modificirana sredstva RNAI
EP2925337B1 (en) * 2012-11-21 2019-07-03 The Trustees of Columbia University in the City of New York Mutant ngal proteins and uses thereof
KR102234623B1 (ko) 2013-05-22 2021-04-02 알닐람 파마슈티칼스 인코포레이티드 Ｔｍｐｒｓｓ6 조성물 및 이의 사용 방법
WO2015099122A1 (ja) 2013-12-26 2015-07-02 学校法人東京医科大学 遺伝子発現制御のための人工ミミックｍｉＲＮＡおよびその用途
CN106068324B (zh) 2013-12-27 2020-12-29 株式会社博纳克 控制基因表达的人工匹配型miRNA及其用途
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DK3607069T3 (da) * 2017-04-05 2022-11-21 Silence Therapeutics Gmbh Produkter og sammensætninger
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JP7406793B2 (ja) 2017-06-23 2023-12-28 ユニバーシティー オブ マサチューセッツ ２テイル自己デリバリー型ｓｉＲＮＡおよび関連方法
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