CN1142130C - 生产反式-(r,r)-放线菌醇的方法 - Google Patents

生产反式-(r,r)-放线菌醇的方法 Download PDF

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Publication number
CN1142130C
CN1142130C CNB98123951XA CN98123951A CN1142130C CN 1142130 C CN1142130 C CN 1142130C CN B98123951X A CNB98123951X A CN B98123951XA CN 98123951 A CN98123951 A CN 98123951A CN 1142130 C CN1142130 C CN 1142130C
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CN
China
Prior art keywords
amino
formula
methyl
acid amides
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB98123951XA
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English (en)
Chinese (zh)
Other versions
CN1223998A (zh
Inventor
伊沃・克拉梅里
伊沃·克拉梅里
・庞特纳
库尔特·庞特纳
格洛・斯卡龙
米切兰格洛·斯卡龙
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
D Sm Ip Asset Co
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F Hoffmann La Roche AG
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Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of CN1223998A publication Critical patent/CN1223998A/zh
Application granted granted Critical
Publication of CN1142130C publication Critical patent/CN1142130C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0046—Ruthenium compounds
    • C07F15/0053—Ruthenium compounds without a metal-carbon linkage
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
    • B01J31/18—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes containing nitrogen, phosphorus, arsenic or antimony as complexing atoms, e.g. in pyridine ligands, or in resonance therewith, e.g. in isocyanide ligands C=N-R or as complexed central atoms
    • B01J31/1805—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes containing nitrogen, phosphorus, arsenic or antimony as complexing atoms, e.g. in pyridine ligands, or in resonance therewith, e.g. in isocyanide ligands C=N-R or as complexed central atoms the ligands containing nitrogen
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
    • B01J31/22—Organic complexes
    • B01J31/2282—Unsaturated compounds used as ligands
    • B01J31/2295—Cyclic compounds, e.g. cyclopentadienyls
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/64—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/385—Saturated compounds containing a keto group being part of a ring
    • C07C49/487—Saturated compounds containing a keto group being part of a ring containing hydroxy groups
    • C07C49/497—Saturated compounds containing a keto group being part of a ring containing hydroxy groups a keto group being part of a six-membered ring
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2231/00—Catalytic reactions performed with catalysts classified in B01J31/00
    • B01J2231/60—Reduction reactions, e.g. hydrogenation
    • B01J2231/64—Reductions in general of organic substrates, e.g. hydride reductions or hydrogenations
    • B01J2231/641—Hydrogenation of organic substrates, i.e. H2 or H-transfer hydrogenations, e.g. Fischer-Tropsch processes
    • B01J2231/643—Hydrogenation of organic substrates, i.e. H2 or H-transfer hydrogenations, e.g. Fischer-Tropsch processes of R2C=O or R2C=NR (R= C, H)
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
    • B01J2531/80—Complexes comprising metals of Group VIII as the central metal
    • B01J2531/82—Metals of the platinum group
    • B01J2531/821—Ruthenium
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/02—Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
    • B01J31/12—Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides containing organo-metallic compounds or metal hydrides
    • B01J31/121—Metal hydrides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CNB98123951XA 1997-11-06 1998-11-06 生产反式-(r,r)-放线菌醇的方法 Expired - Fee Related CN1142130C (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP97119381.8 1997-11-06
EP97119381 1997-11-06
EP98116697.8 1998-09-03
EP98116697 1998-09-03

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CNB2004100032687A Division CN1269828C (zh) 1997-11-06 1998-11-06 一种氨基－酰胺－钌络合物

Publications (2)

Publication Number Publication Date
CN1223998A CN1223998A (zh) 1999-07-28
CN1142130C true CN1142130C (zh) 2004-03-17

Family

ID=26145874

Family Applications (2)

Application Number Title Priority Date Filing Date
CNB98123951XA Expired - Fee Related CN1142130C (zh) 1997-11-06 1998-11-06 生产反式-(r,r)-放线菌醇的方法
CNB2004100032687A Expired - Fee Related CN1269828C (zh) 1997-11-06 1998-11-06 一种氨基－酰胺－钌络合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
CNB2004100032687A Expired - Fee Related CN1269828C (zh) 1997-11-06 1998-11-06 一种氨基－酰胺－钌络合物

Country Status (10)

Country Link
US (2) US6187961B1 (2)
EP (1) EP0915076B1 (2)
JP (1) JP4422808B2 (2)
KR (1) KR100678794B1 (2)
CN (2) CN1142130C (2)
BR (1) BR9804565A (2)
CA (1) CA2253888C (2)
DE (1) DE59802620D1 (2)
DK (1) DK0915076T3 (2)
ES (1) ES2170443T3 (2)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001276690A1 (en) * 2000-08-01 2002-02-13 Shionogi And Co., Ltd. Process for producing alcohol with transition metal complex having amide compound as ligand
GB0204129D0 (en) * 2002-02-21 2002-04-10 Novartis Ag Process for the manufacture of organic compounds
ATE444284T1 (de) * 2002-06-17 2009-10-15 Saltigo Gmbh Verfahren zur herstellung von mono-n- sulfonylierten diaminen
GB0425320D0 (en) 2004-11-17 2004-12-22 Johnson Matthey Plc Diamines
US9416100B2 (en) * 2009-03-17 2016-08-16 Johnson Matthey Public Limited Company Process for hydrogenating ketones in the presence of Ru(II) catalysts
HRP20150617T1 (hr) * 2011-03-10 2015-07-03 Zach System S.P.A. Asimetriäśni postupak redukcije

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4072715A (en) 1974-08-21 1978-02-07 Hoffmann-La Roche Inc. Optically active cyclohexane derivatives
US5011995A (en) * 1987-07-28 1991-04-30 Ciba-Geigy Corporation Process for the preparation of optically active secondary amines
US5543559A (en) * 1994-07-07 1996-08-06 Hoffman-La Roche Inc. Process for the enantioselective hydrogenation of ketosiophorone derivatives
DE19543619A1 (de) 1995-11-23 1997-05-28 Basf Ag Verfahren zur Reindarstellung von trans- und cis-4-Hydroxy-2,2,6-trimethyl-cyclohexan-l-on aus Isomerengemischen
DE69634639T2 (de) 1995-12-06 2006-03-02 Japan Science And Technology Agency, Kawaguchi Verfahren zur herstellung optische aktive verbindungen
GB9706321D0 (en) 1997-03-26 1997-05-14 Zeneca Ltd Catalytic hydrogenation

Also Published As

Publication number Publication date
JP4422808B2 (ja) 2010-02-24
DE59802620D1 (de) 2002-02-21
CA2253888C (en) 2008-09-09
DK0915076T3 (da) 2002-04-22
CN1550482A (zh) 2004-12-01
KR100678794B1 (ko) 2007-06-04
JPH11236345A (ja) 1999-08-31
EP0915076A1 (de) 1999-05-12
EP0915076B1 (de) 2002-01-16
US6300509B1 (en) 2001-10-09
KR19990045041A (ko) 1999-06-25
CN1223998A (zh) 1999-07-28
ES2170443T3 (es) 2002-08-01
BR9804565A (pt) 2000-04-11
CA2253888A1 (en) 1999-05-06
US6187961B1 (en) 2001-02-13
CN1269828C (zh) 2006-08-16

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Owner name: DSM IP CAPITAL CO., LTD.

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Patentee after: D Sm IP asset company

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Granted publication date: 20040317

Termination date: 20171106

CF01 Termination of patent right due to non-payment of annual fee