DK0915076T3 - Fremgangsmåde til fremstilling af trans-(R,R)-actinol - Google Patents

Fremgangsmåde til fremstilling af trans-(R,R)-actinol

Info

Publication number
DK0915076T3
DK0915076T3 DK98120544T DK98120544T DK0915076T3 DK 0915076 T3 DK0915076 T3 DK 0915076T3 DK 98120544 T DK98120544 T DK 98120544T DK 98120544 T DK98120544 T DK 98120544T DK 0915076 T3 DK0915076 T3 DK 0915076T3
Authority
DK
Denmark
Prior art keywords
actinol
trans
preparation
Prior art date
Application number
DK98120544T
Other languages
English (en)
Inventor
Yvo Crameri
Kurt Puentener
Michelangelo Scalone
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK0915076T3 publication Critical patent/DK0915076T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0046—Ruthenium compounds
    • C07F15/0053—Ruthenium compounds without a metal-carbon linkage
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
    • B01J31/18—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes containing nitrogen, phosphorus, arsenic or antimony as complexing atoms, e.g. in pyridine ligands, or in resonance therewith, e.g. in isocyanide ligands C=N-R or as complexed central atoms
    • B01J31/1805—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes containing nitrogen, phosphorus, arsenic or antimony as complexing atoms, e.g. in pyridine ligands, or in resonance therewith, e.g. in isocyanide ligands C=N-R or as complexed central atoms the ligands containing nitrogen
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
    • B01J31/22—Organic complexes
    • B01J31/2282—Unsaturated compounds used as ligands
    • B01J31/2295—Cyclic compounds, e.g. cyclopentadienyls
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/64—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/385—Saturated compounds containing a keto group being part of a ring
    • C07C49/487—Saturated compounds containing a keto group being part of a ring containing hydroxy groups
    • C07C49/497—Saturated compounds containing a keto group being part of a ring containing hydroxy groups a keto group being part of a six-membered ring
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2231/00—Catalytic reactions performed with catalysts classified in B01J31/00
    • B01J2231/60—Reduction reactions, e.g. hydrogenation
    • B01J2231/64—Reductions in general of organic substrates, e.g. hydride reductions or hydrogenations
    • B01J2231/641—Hydrogenation of organic substrates, i.e. H2 or H-transfer hydrogenations, e.g. Fischer-Tropsch processes
    • B01J2231/643—Hydrogenation of organic substrates, i.e. H2 or H-transfer hydrogenations, e.g. Fischer-Tropsch processes of R2C=O or R2C=NR (R= C, H)
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
    • B01J2531/80—Complexes comprising metals of Group VIII as the central metal
    • B01J2531/82—Metals of the platinum group
    • B01J2531/821—Ruthenium
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/02—Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
    • B01J31/12—Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides containing organo-metallic compounds or metal hydrides
    • B01J31/121—Metal hydrides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK98120544T 1997-11-06 1998-10-30 Fremgangsmåde til fremstilling af trans-(R,R)-actinol DK0915076T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97119381 1997-11-06
EP98116697 1998-09-03

Publications (1)

Publication Number Publication Date
DK0915076T3 true DK0915076T3 (da) 2002-04-22

Family

ID=26145874

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98120544T DK0915076T3 (da) 1997-11-06 1998-10-30 Fremgangsmåde til fremstilling af trans-(R,R)-actinol

Country Status (10)

Country Link
US (2) US6187961B1 (da)
EP (1) EP0915076B1 (da)
JP (1) JP4422808B2 (da)
KR (1) KR100678794B1 (da)
CN (2) CN1142130C (da)
BR (1) BR9804565A (da)
CA (1) CA2253888C (da)
DE (1) DE59802620D1 (da)
DK (1) DK0915076T3 (da)
ES (1) ES2170443T3 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001276690A1 (en) * 2000-08-01 2002-02-13 Shionogi And Co., Ltd. Process for producing alcohol with transition metal complex having amide compound as ligand
GB0204129D0 (en) * 2002-02-21 2002-04-10 Novartis Ag Process for the manufacture of organic compounds
ES2331911T3 (es) * 2002-06-17 2010-01-20 Saltigo Gmbh Procedimiento para la preparacion de diaminas mono-n-sulfoniladas.
GB0425320D0 (en) 2004-11-17 2004-12-22 Johnson Matthey Plc Diamines
ES2863542T3 (es) * 2009-03-17 2021-10-11 Johnson Matthey Plc Proceso para la hidrogenación de cetonas en presencia de catalizadores de Ru (II)
JP6013379B2 (ja) * 2011-03-10 2016-10-25 ザック システム エス.ピー.エー.ZaCh System S.p.A. 不斉還元法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4072715A (en) 1974-08-21 1978-02-07 Hoffmann-La Roche Inc. Optically active cyclohexane derivatives
US5011995A (en) * 1987-07-28 1991-04-30 Ciba-Geigy Corporation Process for the preparation of optically active secondary amines
US5543559A (en) * 1994-07-07 1996-08-06 Hoffman-La Roche Inc. Process for the enantioselective hydrogenation of ketosiophorone derivatives
DE19543619A1 (de) 1995-11-23 1997-05-28 Basf Ag Verfahren zur Reindarstellung von trans- und cis-4-Hydroxy-2,2,6-trimethyl-cyclohexan-l-on aus Isomerengemischen
US6184381B1 (en) 1995-12-06 2001-02-06 Japan Science & Technology Corp. Process for preparing optically active compounds
GB9706321D0 (en) 1997-03-26 1997-05-14 Zeneca Ltd Catalytic hydrogenation

Also Published As

Publication number Publication date
CN1269828C (zh) 2006-08-16
US6187961B1 (en) 2001-02-13
JP4422808B2 (ja) 2010-02-24
JPH11236345A (ja) 1999-08-31
CN1550482A (zh) 2004-12-01
EP0915076B1 (de) 2002-01-16
DE59802620D1 (de) 2002-02-21
KR19990045041A (ko) 1999-06-25
US6300509B1 (en) 2001-10-09
CA2253888A1 (en) 1999-05-06
CA2253888C (en) 2008-09-09
KR100678794B1 (ko) 2007-06-04
CN1223998A (zh) 1999-07-28
BR9804565A (pt) 2000-04-11
CN1142130C (zh) 2004-03-17
ES2170443T3 (es) 2002-08-01
EP0915076A1 (de) 1999-05-12

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