CN1154746C - 酶促合成手性胺的改进 - Google Patents

酶促合成手性胺的改进 Download PDF

Info

Publication number: CN1154746C
Authority: CN; China
Prior art keywords: aminopropane; amino; chiral; transaminase; amine
Prior art date: 1998-03-11
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

CNB99803651XA

Other languages

English (en)

Chinese (zh)

Other versions

CN1292828A (zh

Inventor

吴薇

͵�

M·B·巴蒂亚

C·M·刘易斯

��ǡķ

郎伟

王俐

G·W·马恰姆

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

CELGRO Co

Original Assignee

CELGRO Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-03-11

Filing date

1999-03-10

Publication date

2004-06-23

1999-03-10 Application filed by CELGRO Co filed Critical CELGRO Co

2001-04-25 Publication of CN1292828A publication Critical patent/CN1292828A/zh

2004-06-23 Application granted granted Critical

2004-06-23 Publication of CN1154746C publication Critical patent/CN1154746C/zh

2019-03-10 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/001—Amines; Imines
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/005—Amino acids other than alpha- or beta amino acids, e.g. gamma amino acids
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/12—Methionine; Cysteine; Cystine
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures

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Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
Genetics & Genomics (AREA)
General Chemical & Material Sciences (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Analytical Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

CNB99803651XA 1998-03-11 1999-03-10 酶促合成手性胺的改进 Expired - Fee Related CN1154746C (zh)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US7752098P	1998-03-11	1998-03-11
US60/077,520		1998-03-11

Publications (2)

Publication Number	Publication Date
CN1292828A CN1292828A (zh)	2001-04-25
CN1154746C true CN1154746C (zh)	2004-06-23

Family

ID=22138554

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CNB99803651XA Expired - Fee Related CN1154746C (zh)	1998-03-11	1999-03-10	酶促合成手性胺的改进

Country Status (23)

Country	Link
EP (1)	EP1075534B8 (cs)
JP (1)	JP2002505884A (cs)
KR (1)	KR20010034561A (cs)
CN (1)	CN1154746C (cs)
AT (1)	ATE295424T1 (cs)
AU (1)	AU753904B2 (cs)
BR (1)	BR9908797A (cs)
CA (1)	CA2322605A1 (cs)
CZ (1)	CZ295882B6 (cs)
DE (1)	DE69925267T2 (cs)
ES (1)	ES2243051T3 (cs)
FI (1)	FI20001805A7 (cs)
HU (1)	HUP0101056A3 (cs)
MX (1)	MXPA00008573A (cs)
NO (1)	NO319671B1 (cs)
NZ (1)	NZ506405A (cs)
PL (1)	PL342882A1 (cs)
PT (1)	PT1075534E (cs)
RU (1)	RU2213142C2 (cs)
SK (1)	SK284352B6 (cs)
TR (1)	TR200002604T2 (cs)
UA (1)	UA64784C2 (cs)
WO (1)	WO1999046398A1 (cs)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE60013939T2 (de)	1999-03-19	2005-10-06	Sumitomo Chemical Co. Ltd.	Stereoselektive Transaminase, deren kodierende Gen und deren Verwendungen
JP2001190298A (ja) *	2000-01-13	2001-07-17	Kanegafuchi Chem Ind Co Ltd	光学活性ｎ−メチルアミノ酸の製造方法
EP1818411A1 (en) *	2006-02-13	2007-08-15	Lonza AG	Process for the preparation of optically active chiral amines
DE102007042600A1 (de)	2007-09-07	2009-03-12	Evonik Degussa Gmbh	Verfahren zur Herstellung von enantiomerenangereichten Aminen
HUE052297T2 (hu)	2009-01-08	2021-04-28	Codexis Inc	Transzamináz polipeptidek
JP5707344B2 (ja)	2009-02-26	2015-04-30	コデクシス，インコーポレイテッド	トランスアミナーゼ生体触媒
WO2011005477A1 (en)	2009-06-22	2011-01-13	Codexis, Inc.	Transaminase reactions
SG178842A1 (en) *	2009-09-02	2012-04-27	Lonza Ag	A process for the identification and preparation of a (r)-specific omega-transaminase
HUE038434T2 (hu)	2010-06-17	2018-10-29	Codexis Inc	Biokatalizátorok és módszerek (S)-3(1-aminoetil)-fenol szintéziséhez
EP2606139B1 (en)	2010-08-16	2015-07-15	Codexis, Inc.	Biocatalysts and methods for the synthesis of (1r,2r)-2-(3,4-dimethoxyphenethoxy)cyclohexanamine
KR20130119503A (ko) *	2011-08-16	2013-10-31	엠비오 리미티드	광학활성 키랄 아민의 효소적 합성
CN104630170A (zh) *	2013-11-08	2015-05-20	中国科学院天津工业生物技术研究所	一种来源于里氏木霉的新(r)-转氨酶及其应用
CN114134126B (zh) *	2021-10-28	2023-12-05	浙江大学杭州国际科创中心	转氨酶及其突变体在制备(s)-1-甲氧基-2-丙胺中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4950606A (en) *	1989-06-22	1990-08-21	Celgene Corporation	Enantiomeric enrichment and stereoselective synthesis of chiral amines
US5300437A (en) *	1989-06-22	1994-04-05	Celgene Corporation	Enantiomeric enrichment and stereoselective synthesis of chiral amines
DE69635082T2 (de) *	1995-10-23	2006-06-01	Kaneka Corp.	Verfahren zur herstellung optisch aktiver aminoverbindungen

1999
- 1999-03-10 RU RU2000125535/13A patent/RU2213142C2/ru active IP Right Revival
- 1999-03-10 NZ NZ506405A patent/NZ506405A/en not_active IP Right Cessation
- 1999-03-10 DE DE69925267T patent/DE69925267T2/de not_active Expired - Fee Related
- 1999-03-10 MX MXPA00008573A patent/MXPA00008573A/es active IP Right Grant
- 1999-03-10 AT AT99911250T patent/ATE295424T1/de not_active IP Right Cessation
- 1999-03-10 SK SK1338-2000A patent/SK284352B6/sk unknown
- 1999-03-10 JP JP2000535765A patent/JP2002505884A/ja not_active Withdrawn
- 1999-03-10 CZ CZ20003177A patent/CZ295882B6/cs not_active IP Right Cessation
- 1999-03-10 CA CA002322605A patent/CA2322605A1/en not_active Abandoned
- 1999-03-10 EP EP99911250A patent/EP1075534B8/en not_active Expired - Lifetime
- 1999-03-10 TR TR2000/02604T patent/TR200002604T2/xx unknown
- 1999-03-10 KR KR1020007009945A patent/KR20010034561A/ko not_active Abandoned
- 1999-03-10 ES ES99911250T patent/ES2243051T3/es not_active Expired - Lifetime
- 1999-03-10 AU AU29938/99A patent/AU753904B2/en not_active Ceased
- 1999-03-10 WO PCT/US1999/005150 patent/WO1999046398A1/en not_active Ceased
- 1999-03-10 CN CNB99803651XA patent/CN1154746C/zh not_active Expired - Fee Related
- 1999-03-10 BR BR9908797-9A patent/BR9908797A/pt not_active IP Right Cessation
- 1999-03-10 PL PL99342882A patent/PL342882A1/xx not_active IP Right Cessation
- 1999-03-10 HU HU0101056A patent/HUP0101056A3/hu unknown
- 1999-03-10 PT PT99911250T patent/PT1075534E/pt unknown
- 1999-10-03 UA UA2000105759A patent/UA64784C2/uk unknown
2000
- 2000-08-11 NO NO20004036A patent/NO319671B1/no unknown
- 2000-08-15 FI FI20001805A patent/FI20001805A7/fi not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP1075534B1 (en)	2005-05-11
RU2213142C2 (ru)	2003-09-27
EP1075534A1 (en)	2001-02-14
NO20004036D0 (no)	2000-08-11
NO319671B1 (no)	2005-09-05
HUP0101056A2 (hu)	2001-07-30
JP2002505884A (ja)	2002-02-26
EP1075534B8 (en)	2005-07-06
CZ295882B6 (cs)	2005-11-16
MXPA00008573A (es)	2003-07-14
SK13382000A3 (sk)	2001-05-10
ATE295424T1 (de)	2005-05-15
AU753904B2 (en)	2002-10-31
HUP0101056A3 (en)	2006-03-28
NZ506405A (en)	2003-08-29
TR200002604T2 (tr)	2000-11-21
NO20004036L (no)	2000-10-27
FI20001805A7 (fi)	2000-09-11
KR20010034561A (ko)	2001-04-25
AU2993899A (en)	1999-09-27
CA2322605A1 (en)	1999-09-16
WO1999046398A1 (en)	1999-09-16
HK1035000A1 (en)	2001-11-09
UA64784C2 (en)	2004-03-15
PL342882A1 (en)	2001-07-16
SK284352B6 (sk)	2005-02-04
CN1292828A (zh)	2001-04-25
CZ20003177A3 (cs)	2000-12-13
EP1075534A4 (en)	2003-07-09
BR9908797A (pt)	2000-12-12
PT1075534E (pt)	2005-09-30
DE69925267T2 (de)	2006-01-26
FI20001805L (fi)	2000-08-15
ES2243051T3 (es)	2005-11-16
DE69925267D1 (de)	2005-06-16

Legal Events

Date	Code	Title
2001-04-25	C06	Publication
2001-04-25	PB01	Publication
2001-05-30	C10	Entry into substantive examination
2001-05-30	SE01	Entry into force of request for substantive examination
2004-06-23	C14	Grant of patent or utility model
2004-06-23	GR01	Patent grant
2008-05-07	C19	Lapse of patent right due to non-payment of the annual fee
2008-05-07	CF01	Termination of patent right due to non-payment of annual fee

Publication	Publication Date	Title
RU2116347C1 (ru)	1998-07-27	Способ стереоселективного синтеза хиральных аминов
US4518692A (en)	1985-05-21	Production of L-amino acids by transamination
US4826766A (en)	1989-05-02	Production of amino acids using coupled aminotransferases
CN1154746C (zh)	2004-06-23	酶促合成手性胺的改进
US20090325224A1 (en)	2009-12-31	Process for preparation of optically active n-protected 3-aminopyrrolidine or optically active n-protected 3-aminopiperidine and the corresponding ketones by optical resolution of the racemic amine mixtures employing a bacterial omega-transaminase
EP0135846B1 (en)	1990-08-16	Production of l-amino acids by transamination
Kamphuis et al.	2005	New developments in the chemo-enzymatic production of amino acids
JPS63500004A (ja)	1988-01-07	光学活性な有機化合物の調整方法
US6133018A (en)	2000-10-17	Enzymatic synthesis of chiral amines using -2-amino propane as amine donor
EP0330695A1 (en)	1989-09-06	Process for preparation of organic chemicals
US4880738A (en)	1989-11-14	Production of amino acids using coupled enzyme systems
Winkler et al.	1995	Principles and results of stable isotope labelling of L-α-Aminoacids by combined chemical and enzymatic methods
US5587319A (en)	1996-12-24	Process for the preparation of L-phosphinothricin using transaminases of different specificities in a linked process
HK1035000B (en)	2005-12-23	Improvements in the enzymatic synthesis of chiral amines
JP2674078B2 (ja)	1997-11-05	Ｄ−α−アミノ酸の製造法
JP2004057014A (ja)	2004-02-26	芳香族アミノ酸のラセミ化方法、芳香族アミノ酸の光学活性体の製造方法並びに芳香族アミノ酸のラセミ化活性を有する微生物および酵素
JPH02124087A (ja)	1990-05-11	シユードモナス属細菌の培養方法
CZ355697A3 (cs)	1998-06-17	Způsob stereoselektivní syntézy jedné chirální formy aminu