CN1196010C - 以硅氧烷为基础的可润湿透镜 - Google Patents

以硅氧烷为基础的可润湿透镜 Download PDF

Info

Publication number: CN1196010C
Authority: CN; China
Prior art keywords: silane; vinyl; coupling agent; aminopropyl; functional
Prior art date: 1998-09-23
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

CNB991202333A

Other languages

English (en)

Chinese (zh)

Other versions

CN1249443A (zh

Inventor

J·S·詹

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Johnson and Johnson Vision Care Inc

Original Assignee

Johnson and Johnson Vision Products Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-09-23

Filing date

1999-09-23

Publication date

2005-04-06

1999-09-23 Application filed by Johnson and Johnson Vision Products Inc filed Critical Johnson and Johnson Vision Products Inc

2000-04-05 Publication of CN1249443A publication Critical patent/CN1249443A/zh

2005-04-06 Application granted granted Critical

2005-04-06 Publication of CN1196010C publication Critical patent/CN1196010C/zh

2019-09-23 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical class [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 title description 18
229920001477 hydrophilic polymer Polymers 0.000 claims abstract description 16
239000006087 Silane Coupling Agent Substances 0.000 claims abstract description 15
BLRPTPMANUNPDV-UHFFFAOYSA-N Silane Chemical compound [SiH4] BLRPTPMANUNPDV-UHFFFAOYSA-N 0.000 claims abstract description 13
229910000077 silane Inorganic materials 0.000 claims abstract description 11
239000011248 coating agent Substances 0.000 claims description 31
238000000576 coating method Methods 0.000 claims description 31
-1 glycidoxypropyl Chemical group 0.000 claims description 28
239000007822 coupling agent Substances 0.000 claims description 26
QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 15
239000000178 monomer Substances 0.000 claims description 15
239000000203 mixture Substances 0.000 claims description 11
LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims description 9
NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 8
229920002554 vinyl polymer Polymers 0.000 claims description 7
WYTZZXDRDKSJID-UHFFFAOYSA-N (3-aminopropyl)triethoxysilane Chemical compound CCO[Si](OCC)(OCC)CCCN WYTZZXDRDKSJID-UHFFFAOYSA-N 0.000 claims description 6
SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims description 6
239000000126 substance Substances 0.000 claims description 6
JECYNCQXXKQDJN-UHFFFAOYSA-N 2-(2-methylhexan-2-yloxymethyl)oxirane Chemical compound CCCCC(C)(C)OCC1CO1 JECYNCQXXKQDJN-UHFFFAOYSA-N 0.000 claims description 4
IMROMDMJAWUWLK-UHFFFAOYSA-N Ethenol Chemical compound OC=C IMROMDMJAWUWLK-UHFFFAOYSA-N 0.000 claims description 4
WOBHKFSMXKNTIM-UHFFFAOYSA-N Hydroxyethyl methacrylate Chemical compound CC(=C)C(=O)OCCO WOBHKFSMXKNTIM-UHFFFAOYSA-N 0.000 claims description 4
WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 claims description 4
229920003171 Poly (ethylene oxide) Polymers 0.000 claims description 4
125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 claims description 4
OMIGHNLMNHATMP-UHFFFAOYSA-N 2-hydroxyethyl prop-2-enoate Chemical compound OCCOC(=O)C=C OMIGHNLMNHATMP-UHFFFAOYSA-N 0.000 claims description 3
KHLRJDNGHBXOSV-UHFFFAOYSA-N 5-trimethoxysilylpentane-1,3-diamine Chemical compound CO[Si](OC)(OC)CCC(N)CCN KHLRJDNGHBXOSV-UHFFFAOYSA-N 0.000 claims description 3
HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 claims description 3
IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 claims description 3
125000002091 cationic group Chemical group 0.000 claims description 3
FQPSGWSUVKBHSU-UHFFFAOYSA-N methacrylamide Chemical compound CC(=C)C(N)=O FQPSGWSUVKBHSU-UHFFFAOYSA-N 0.000 claims description 3
YUYCVXFAYWRXLS-UHFFFAOYSA-N trimethoxysilane Chemical compound CO[SiH](OC)OC YUYCVXFAYWRXLS-UHFFFAOYSA-N 0.000 claims description 3
QDHHCQZDFGDHMP-UHFFFAOYSA-N Chloramine Chemical compound ClN QDHHCQZDFGDHMP-UHFFFAOYSA-N 0.000 claims description 2
239000004593 Epoxy Substances 0.000 claims description 2
239000000460 chlorine Substances 0.000 claims description 2
125000005395 methacrylic acid group Chemical group 0.000 claims description 2
229920000151 polyglycol Polymers 0.000 claims description 2
239000010695 polyglycol Substances 0.000 claims description 2
150000003254 radicals Chemical class 0.000 claims description 2
239000004372 Polyvinyl alcohol Substances 0.000 claims 2
229920002125 Sokalan® Polymers 0.000 claims 2
239000004584 polyacrylic acid Substances 0.000 claims 2
229920002451 polyvinyl alcohol Polymers 0.000 claims 2
229920000191 poly(N-vinyl pyrrolidone) Polymers 0.000 claims 1
229920002401 polyacrylamide Polymers 0.000 claims 1
229920001296 polysiloxane Polymers 0.000 abstract description 10
239000003795 chemical substances by application Substances 0.000 abstract 1
238000000034 method Methods 0.000 description 12
229920000642 polymer Polymers 0.000 description 12
239000000243 solution Substances 0.000 description 9
239000000463 material Substances 0.000 description 8
BAPJBEWLBFYGME-UHFFFAOYSA-N Methyl acrylate Chemical compound COC(=O)C=C BAPJBEWLBFYGME-UHFFFAOYSA-N 0.000 description 7
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 6
239000004205 dimethyl polysiloxane Substances 0.000 description 5
235000013870 dimethyl polysiloxane Nutrition 0.000 description 5
CXQXSVUQTKDNFP-UHFFFAOYSA-N octamethyltrisiloxane Chemical compound C[Si](C)(C)O[Si](C)(C)O[Si](C)(C)C CXQXSVUQTKDNFP-UHFFFAOYSA-N 0.000 description 5
238000004987 plasma desorption mass spectroscopy Methods 0.000 description 5
229920000435 poly(dimethylsiloxane) Polymers 0.000 description 5
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
239000007864 aqueous solution Substances 0.000 description 4
238000009736 wetting Methods 0.000 description 4
NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 description 3
UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 3
CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 description 3
YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 3
230000008859 change Effects 0.000 description 3
238000006243 chemical reaction Methods 0.000 description 3
MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 description 3
VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 3
239000003960 organic solvent Substances 0.000 description 3
238000006116 polymerization reaction Methods 0.000 description 3
PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
239000002253 acid Substances 0.000 description 2
125000003118 aryl group Chemical group 0.000 description 2
125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 description 2
230000000694 effects Effects 0.000 description 2
238000005516 engineering process Methods 0.000 description 2
125000001183 hydrocarbyl group Chemical group 0.000 description 2
239000007943 implant Substances 0.000 description 2
230000004048 modification Effects 0.000 description 2
238000012986 modification Methods 0.000 description 2
BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 2
229920005573 silicon-containing polymer Polymers 0.000 description 2
NLAIHECABDOZBR-UHFFFAOYSA-M sodium 2,2-bis(2-methylprop-2-enoyloxymethyl)butyl 2-methylprop-2-enoate 2-hydroxyethyl 2-methylprop-2-enoate 2-methylprop-2-enoate Chemical compound [Na+].CC(=C)C([O-])=O.CC(=C)C(=O)OCCO.CCC(COC(=O)C(C)=C)(COC(=O)C(C)=C)COC(=O)C(C)=C NLAIHECABDOZBR-UHFFFAOYSA-M 0.000 description 2
238000004381 surface treatment Methods 0.000 description 2
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
GNSFRPWPOGYVLO-UHFFFAOYSA-N 3-hydroxypropyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OCCCO GNSFRPWPOGYVLO-UHFFFAOYSA-N 0.000 description 1
GAWIXWVDTYZWAW-UHFFFAOYSA-N C[CH]O Chemical group C[CH]O GAWIXWVDTYZWAW-UHFFFAOYSA-N 0.000 description 1
VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 description 1
239000005977 Ethylene Substances 0.000 description 1
CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 description 1
239000006057 Non-nutritive feed additive Substances 0.000 description 1
GOOHAUXETOMSMM-UHFFFAOYSA-N Propylene oxide Chemical compound CC1CO1 GOOHAUXETOMSMM-UHFFFAOYSA-N 0.000 description 1
229910020175 SiOH Inorganic materials 0.000 description 1
XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical class [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 1
AACDMFYQIDJLBH-UHFFFAOYSA-N [O].CN(C)[SiH3] Chemical compound [O].CN(C)[SiH3] AACDMFYQIDJLBH-UHFFFAOYSA-N 0.000 description 1
PYGXUPRQBBNETH-UHFFFAOYSA-N acetic acid;2-hydroxypropyl prop-2-enoate Chemical compound CC(O)=O.CC(O)COC(=O)C=C PYGXUPRQBBNETH-UHFFFAOYSA-N 0.000 description 1
VONAITTUXGVFME-UHFFFAOYSA-N acetic acid;oxirane Chemical compound C1CO1.CC(O)=O.CC(O)=O VONAITTUXGVFME-UHFFFAOYSA-N 0.000 description 1
239000002671 adjuvant Substances 0.000 description 1
125000000217 alkyl group Chemical group 0.000 description 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
210000001124 body fluid Anatomy 0.000 description 1
239000010839 body fluid Substances 0.000 description 1
235000008429 bread Nutrition 0.000 description 1
239000003054 catalyst Substances 0.000 description 1
239000003518 caustics Substances 0.000 description 1
150000001875 compounds Chemical class 0.000 description 1
210000004087 cornea Anatomy 0.000 description 1
230000007797 corrosion Effects 0.000 description 1
238000005260 corrosion Methods 0.000 description 1
230000008878 coupling Effects 0.000 description 1
238000010168 coupling process Methods 0.000 description 1
238000005859 coupling reaction Methods 0.000 description 1
238000004132 cross linking Methods 0.000 description 1
230000007812 deficiency Effects 0.000 description 1
210000003560 epithelium corneal Anatomy 0.000 description 1
125000005670 ethenylalkyl group Chemical group 0.000 description 1
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
239000004811 fluoropolymer Substances 0.000 description 1
229920002313 fluoropolymer Polymers 0.000 description 1
235000011187 glycerol Nutrition 0.000 description 1
239000000017 hydrogel Substances 0.000 description 1
239000001257 hydrogen Substances 0.000 description 1
229910052739 hydrogen Inorganic materials 0.000 description 1
230000002209 hydrophobic effect Effects 0.000 description 1
238000006459 hydrosilylation reaction Methods 0.000 description 1
230000006872 improvement Effects 0.000 description 1
239000004615 ingredient Substances 0.000 description 1
238000001746 injection moulding Methods 0.000 description 1
150000002632 lipids Chemical class 0.000 description 1
238000004519 manufacturing process Methods 0.000 description 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
238000002156 mixing Methods 0.000 description 1
YPHQUSNPXDGUHL-UHFFFAOYSA-N n-methylprop-2-enamide Chemical compound CNC(=O)C=C YPHQUSNPXDGUHL-UHFFFAOYSA-N 0.000 description 1
230000003287 optical effect Effects 0.000 description 1
239000001301 oxygen Substances 0.000 description 1
229910052760 oxygen Inorganic materials 0.000 description 1
239000003973 paint Substances 0.000 description 1
230000035699 permeability Effects 0.000 description 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
238000002360 preparation method Methods 0.000 description 1
125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
102000004169 proteins and genes Human genes 0.000 description 1
108090000623 proteins and genes Proteins 0.000 description 1
239000000985 reactive dye Substances 0.000 description 1
FZHAPNGMFPVSLP-UHFFFAOYSA-N silanamine Chemical compound [SiH3]N FZHAPNGMFPVSLP-UHFFFAOYSA-N 0.000 description 1
229920000260 silastic Polymers 0.000 description 1
229920002379 silicone rubber Polymers 0.000 description 1
210000001519 tissue Anatomy 0.000 description 1
125000003944 tolyl group Chemical group 0.000 description 1
238000002834 transmittance Methods 0.000 description 1
ZIBGPFATKBEMQZ-UHFFFAOYSA-N triethylene glycol Chemical compound OCCOCCOCCO ZIBGPFATKBEMQZ-UHFFFAOYSA-N 0.000 description 1
125000000026 trimethylsilyl group Chemical group [H]C([H])([H])[Si]([*])(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
UKRDPEFKFJNXQM-UHFFFAOYSA-N vinylsilane Chemical class [SiH3]C=C UKRDPEFKFJNXQM-UHFFFAOYSA-N 0.000 description 1
125000005023 xylyl group Chemical group 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
- A61F2/16—Intraocular lenses
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J7/00—Chemical treatment or coating of shaped articles made of macromolecular substances
- C08J7/04—Coating
- C08J7/0427—Coating with only one layer of a composition containing a polymer binder
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J7/00—Chemical treatment or coating of shaped articles made of macromolecular substances
- C08J7/04—Coating
- C08J7/043—Improving the adhesiveness of the coatings per se, e.g. forming primers
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J7/00—Chemical treatment or coating of shaped articles made of macromolecular substances
- C08J7/04—Coating
- C08J7/056—Forming hydrophilic coatings
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J7/00—Chemical treatment or coating of shaped articles made of macromolecular substances
- C08J7/04—Coating
- C08J7/06—Coating with compositions not containing macromolecular substances
- C08J7/065—Low-molecular-weight organic substances, e.g. absorption of additives in the surface of the article
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
- G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
- G02B1/041—Lenses
- G02B1/043—Contact lenses
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2383/00—Characterised by the use of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon with or without sulfur, nitrogen, oxygen, or carbon only; Derivatives of such polymers
- C08J2383/04—Polysiloxanes

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Polymers & Plastics (AREA)
Organic Chemistry (AREA)
Physics & Mathematics (AREA)
General Physics & Mathematics (AREA)
Optics & Photonics (AREA)
Ophthalmology & Optometry (AREA)
Biomedical Technology (AREA)
General Health & Medical Sciences (AREA)
Transplantation (AREA)
Engineering & Computer Science (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Vascular Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Oral & Maxillofacial Surgery (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Materials For Medical Uses (AREA)
Coating Of Shaped Articles Made Of Macromolecular Substances (AREA)
Eyeglasses (AREA)
Compositions Of Macromolecular Compounds (AREA)
Laminated Bodies (AREA)
Paints Or Removers (AREA)
Silicon Polymers (AREA)

CNB991202333A 1998-09-23 1999-09-23 以硅氧烷为基础的可润湿透镜 Expired - Fee Related CN1196010C (zh)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US09/159034		1998-09-23
US09/159,034 US6099852A (en)	1998-09-23	1998-09-23	Wettable silicone-based lenses

Publications (2)

Publication Number	Publication Date
CN1249443A CN1249443A (zh)	2000-04-05
CN1196010C true CN1196010C (zh)	2005-04-06

Family

ID=22570803

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CNB991202333A Expired - Fee Related CN1196010C (zh)	1998-09-23	1999-09-23	以硅氧烷为基础的可润湿透镜

Country Status (11)

Country	Link
US (1)	US6099852A (de)
EP (1)	EP0989418A3 (de)
JP (1)	JP2000137195A (de)
KR (1)	KR20000034933A (de)
CN (1)	CN1196010C (de)
AR (1)	AR025805A1 (de)
AU (1)	AU757262B2 (de)
BR (1)	BR9904255B1 (de)
CA (1)	CA2283041A1 (de)
SG (1)	SG85676A1 (de)
TW (1)	TWI229759B (de)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6367929B1 (en) *	1998-03-02	2002-04-09	Johnson & Johnson Vision Care, Inc.	Hydrogel with internal wetting agent
US7052131B2 (en) *	2001-09-10	2006-05-30	J&J Vision Care, Inc.	Biomedical devices containing internal wetting agents
US6822016B2 (en)	2001-09-10	2004-11-23	Johnson & Johnson Vision Care, Inc.	Biomedical devices containing internal wetting agents
US6440571B1 (en) *	1999-05-20	2002-08-27	Bausch & Lomb Incorporated	Surface treatment of silicone medical devices with reactive hydrophilic polymers
WO2001034311A1 (en) *	1999-11-05	2001-05-17	Bausch & Lomb Incorporated	Surface treatment of rigid gas permeable contact lenses
AU1583601A (en) *	1999-11-05	2001-06-06	Bausch & Lomb Incorporated	Surface treatment of non-plasma treated silicone hydrogel contact lenses
US6599559B1 (en) *	2000-04-03	2003-07-29	Bausch & Lomb Incorporated	Renewable surface treatment of silicone medical devices with reactive hydrophilic polymers
US6689480B2 (en) *	2000-05-10	2004-02-10	Toray Industries, Inc.	Surface-treated plastic article and method of surface treatment
US6773107B2 (en) *	2000-08-17	2004-08-10	Novartis Ag	Soft translating contact lens for presbyopia
US6852353B2 (en)	2000-08-24	2005-02-08	Novartis Ag	Process for surface modifying substrates and modified substrates resulting therefrom
SK2152003A3 (en)	2000-08-24	2003-08-05	Novartis Ag	Process for surface modifying substrates and modified substrates resulting therefrom
CN1266197C (zh) *	2000-09-19	2006-07-26	博士伦公司	施涂聚合物透镜涂层的方法
US6861123B2 (en) *	2000-12-01	2005-03-01	Johnson & Johnson Vision Care, Inc.	Silicone hydrogel contact lens
US7060288B2 (en) *	2001-02-28	2006-06-13	Timothy Charles Hughes	Biomedical devices
US20050064012A1 (en) *	2001-07-17	2005-03-24	Baylor College Of Medicine	Process for causing myopic shift in vision
US7879267B2 (en) *	2001-08-02	2011-02-01	J&J Vision Care, Inc.	Method for coating articles by mold transfer
GB0122393D0 (en) *	2001-09-17	2001-11-07	Polybiomed Ltd	Treating metal surfaces to enhance bio-compatibility
US7270678B2 (en) *	2002-06-28	2007-09-18	Bausch & Lomb Incorporated	Surface modification of functional group-containing medical devices with catalyst-containing reactive polymer system
US7083646B2 (en) *	2002-06-28	2006-08-01	Bausch & Lomb Incorporated	Surface modification of functional group-containing intraocular lenses
US20070138692A1 (en) *	2002-09-06	2007-06-21	Ford James D	Process for forming clear, wettable silicone hydrogel articles
US20040120982A1 (en) *	2002-12-19	2004-06-24	Zanini Diana	Biomedical devices with coatings attached via latent reactive components
US20060193894A1 (en) *	2005-02-28	2006-08-31	Jen James S	Methods for providing biomedical devices with hydrophilic antimicrobial coatings
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1998
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1999
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- 1999-09-16 AU AU48767/99A patent/AU757262B2/en not_active Ceased
- 1999-09-20 BR BRPI9904255-0A patent/BR9904255B1/pt not_active IP Right Cessation
- 1999-09-21 KR KR1019990040604A patent/KR20000034933A/ko not_active Withdrawn
- 1999-09-22 JP JP11269140A patent/JP2000137195A/ja active Pending
- 1999-09-22 EP EP99307497A patent/EP0989418A3/de not_active Withdrawn
- 1999-09-22 AR ARP990104768A patent/AR025805A1/es active IP Right Grant
- 1999-09-23 CA CA002283041A patent/CA2283041A1/en not_active Abandoned
- 1999-09-23 CN CNB991202333A patent/CN1196010C/zh not_active Expired - Fee Related
- 1999-10-21 TW TW088116336A patent/TWI229759B/zh not_active IP Right Cessation

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EP0989418A2 (de)	2000-03-29
EP0989418A3 (de)	2001-04-04
KR20000034933A (ko)	2000-06-26
BR9904255B1 (pt)	2011-05-31
US6099852A (en)	2000-08-08
CN1249443A (zh)	2000-04-05
SG85676A1 (en)	2002-01-15
AU757262B2 (en)	2003-02-13
AR025805A1 (es)	2002-12-18
CA2283041A1 (en)	2000-03-23
AU4876799A (en)	2000-03-30
JP2000137195A (ja)	2000-05-16
TWI229759B (en)	2005-03-21
BR9904255A (pt)	2001-04-17

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2005-04-06	C14	Grant of patent or utility model
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