CN1275575A - 合成核苷类似物的方法 - Google Patents

合成核苷类似物的方法 Download PDF

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Publication number
CN1275575A
CN1275575A CN00107145A CN00107145A CN1275575A CN 1275575 A CN1275575 A CN 1275575A CN 00107145 A CN00107145 A CN 00107145A CN 00107145 A CN00107145 A CN 00107145A CN 1275575 A CN1275575 A CN 1275575A
Authority
CN
China
Prior art keywords
yuan
heteroaryls
dmso
halogen
alkylidene group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN00107145A
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English (en)
Chinese (zh)
Inventor
R·W·斯科特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Products Inc
Original Assignee
Pfizer Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc filed Critical Pfizer Products Inc
Publication of CN1275575A publication Critical patent/CN1275575A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/14—Pyrrolo-pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
CN00107145A 1999-05-11 2000-05-10 合成核苷类似物的方法 Pending CN1275575A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13365199P 1999-05-11 1999-05-11
US60/133651 1999-05-11

Publications (1)

Publication Number Publication Date
CN1275575A true CN1275575A (zh) 2000-12-06

Family

ID=22459680

Family Applications (1)

Application Number Title Priority Date Filing Date
CN00107145A Pending CN1275575A (zh) 1999-05-11 2000-05-10 合成核苷类似物的方法

Country Status (22)

Country Link
US (1) US6271370B1 (2)
EP (1) EP1052264B1 (2)
JP (1) JP2001011092A (2)
KR (1) KR100403900B1 (2)
CN (1) CN1275575A (2)
AR (1) AR028991A1 (2)
AT (1) ATE291582T1 (2)
AU (1) AU3401100A (2)
BR (1) BR0002089A (2)
CA (1) CA2307951A1 (2)
CZ (1) CZ20001710A3 (2)
DE (1) DE60018833D1 (2)
HU (1) HUP0001843A3 (2)
ID (1) ID25992A (2)
IL (1) IL136027A0 (2)
IN (1) IN186850B (2)
MX (1) MXPA00004532A (2)
PL (1) PL340109A1 (2)
RU (1) RU2200738C2 (2)
TR (1) TR200001340A2 (2)
YU (1) YU25500A (2)
ZA (1) ZA200002263B (2)

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Also Published As

Publication number Publication date
RU2200738C2 (ru) 2003-03-20
EP1052264A2 (en) 2000-11-15
JP2001011092A (ja) 2001-01-16
ZA200002263B (en) 2001-12-24
KR20010069193A (ko) 2001-07-23
BR0002089A (pt) 2001-01-02
AR028991A1 (es) 2003-06-04
CA2307951A1 (en) 2000-11-11
YU25500A (sh) 2003-08-29
HUP0001843A2 (hu) 2001-06-28
HU0001843D0 (en) 2000-07-28
MXPA00004532A (es) 2002-03-08
KR100403900B1 (ko) 2003-11-01
IN186850B (2) 2001-11-24
PL340109A1 (en) 2000-11-20
IL136027A0 (en) 2001-05-20
ATE291582T1 (de) 2005-04-15
EP1052264B1 (en) 2005-03-23
ID25992A (id) 2000-11-16
DE60018833D1 (de) 2005-04-28
HUP0001843A3 (en) 2001-09-28
TR200001340A2 (tr) 2000-12-21
US6271370B1 (en) 2001-08-07
EP1052264A3 (en) 2001-06-13
CZ20001710A3 (cs) 2001-09-12
AU3401100A (en) 2000-11-16

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