CN1299116C - 封入信号产生物质的芯－壳型粒子及其制造方法 - Google Patents

封入信号产生物质的芯－壳型粒子及其制造方法 Download PDF

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Publication number
CN1299116C
CN1299116C CNB028111001A CN02811100A CN1299116C CN 1299116 C CN1299116 C CN 1299116C CN B028111001 A CNB028111001 A CN B028111001A CN 02811100 A CN02811100 A CN 02811100A CN 1299116 C CN1299116 C CN 1299116C
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CN
China
Prior art keywords
signal
core
group
generating substance
shell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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CNB028111001A
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English (en)
Chinese (zh)
Other versions
CN1618019A (zh
Inventor
片冈一则
长崎幸夫
柴田直哉
星野信广
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nanokaria K K
Mitsubishi Chemical Safety Institute Ltd
Original Assignee
NanoCarrier Co Ltd
Mitsubishi Kagaku Iatron Inc
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Publication of CN1618019A publication Critical patent/CN1618019A/zh
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Anticipated expiration legal-status Critical
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S525/00—Synthetic resins or natural rubbers -- part of the class 520 series
    • Y10S525/902—Core-shell
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated
    • Y10T428/2998—Coated including synthetic resin or polymer

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Developing Agents For Electrophotography (AREA)
CNB028111001A 2001-05-30 2002-05-30 封入信号产生物质的芯－壳型粒子及其制造方法 Expired - Fee Related CN1299116C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP161787/2001 2001-05-30
JP2001161787 2001-05-30

Publications (2)

Publication Number Publication Date
CN1618019A CN1618019A (zh) 2005-05-18
CN1299116C true CN1299116C (zh) 2007-02-07

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CNB028111001A Expired - Fee Related CN1299116C (zh) 2001-05-30 2002-05-30 封入信号产生物质的芯－壳型粒子及其制造方法

Country Status (8)

Country Link
US (1) US6881484B2 (de)
EP (1) EP1398635B1 (de)
JP (1) JP4167975B2 (de)
KR (1) KR20040010667A (de)
CN (1) CN1299116C (de)
AT (1) ATE423970T1 (de)
DE (1) DE60231301D1 (de)
WO (1) WO2002097436A1 (de)

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WO2004056894A1 (ja) * 2002-12-19 2004-07-08 Nanocarrier Co., Ltd. 蛍光体または造影剤を含有するラテックスポリマー粒子およびそれらの製造方法
US7410699B2 (en) * 2003-10-10 2008-08-12 Japan Science And Technology Agency Finely particulate composite containing carbon compound encapsulated in a polymer micelle of a block copolymer
JP4355190B2 (ja) 2003-10-10 2009-10-28 独立行政法人科学技術振興機構 生物学的被検体の高速検出方法
CA2544262A1 (en) * 2003-10-28 2005-05-12 Bioarray Solutions Ltd. Gel-shell beads with adsorbed or bound biomolecules
US7449605B2 (en) * 2003-11-03 2008-11-11 Ilypsa, Inc. Crosslinked amine polymers
US7335795B2 (en) 2004-03-22 2008-02-26 Ilypsa, Inc. Crosslinked amine polymers
US7608674B2 (en) 2003-11-03 2009-10-27 Ilypsa, Inc. Pharmaceutical compositions comprising cross-linked small molecule amine polymers
WO2005073370A1 (ja) * 2004-01-31 2005-08-11 Transparent Inc. 酵素複合体
US7429394B2 (en) * 2004-03-30 2008-09-30 Relypsa, Inc. Ion binding compositions
US8192758B2 (en) 2004-03-30 2012-06-05 Relypsa, Inc. Ion binding compositions
US8282960B2 (en) * 2004-03-30 2012-10-09 Relypsa, Inc. Ion binding compositions
KR101153035B1 (ko) * 2004-03-30 2012-06-11 리립사, 인크. 이온 결합 조성물
US7854924B2 (en) * 2004-03-30 2010-12-21 Relypsa, Inc. Methods and compositions for treatment of ion imbalances
US7556799B2 (en) * 2004-03-30 2009-07-07 Relypsa, Inc. Ion binding polymers and uses thereof
KR101088579B1 (ko) 2004-10-04 2011-12-05 재단법인서울대학교산학협력재단 젤 타입의 코어-쉘 수지
KR101288729B1 (ko) 2005-04-01 2013-07-23 인터자인 테크놀로지스, 인코포레이티드 약물 전달용 중합체성 마이셀
JP2009510126A (ja) * 2005-09-30 2009-03-12 レリプサ， インコーポレイテッド 哺乳類の胃腸管からカリウムイオンを選択的に除去するための方法および組成物
CN101321519A (zh) * 2005-09-30 2008-12-10 伊立普萨公司 制备含有交联壳的核-壳型复合物的方法及其得到的核-壳型复合物
JP2007146149A (ja) * 2005-11-02 2007-06-14 Fujifilm Corp 蛍光性重合体微粒子、蛍光性重合体微粒子の製造方法、蛍光検出キット及び蛍光検出方法
EP2046492B1 (de) * 2006-07-31 2012-06-06 Topchim N.V. Teilchen in form eines verkapselten tröpfchens und herstellungsverfahren dafür
TWI325025B (en) * 2006-09-14 2010-05-21 Taiwan Textile Res Inst Ph-adjustable fabric made by adding amphoteric polymer composite nanoparticles
JP2008074892A (ja) * 2006-09-19 2008-04-03 Fujifilm Corp 蛍光性重合体微粒子セット、蛍光検出用複合体セット、蛍光性重合体微粒子組成物及び蛍光検出方法
EP4201408B1 (de) * 2008-08-22 2025-06-25 Vifor (International) Ltd. Vernetzte kationenaustauschpolymere, zusammensetzungen und verwendung bei der behandlung von hyperkalämie
WO2010022381A1 (en) * 2008-08-22 2010-02-25 Relypsa, Inc. Treating hyperkalemia with crosslinked cation exchange polymers of improved physical properties
WO2010022380A2 (en) 2008-08-22 2010-02-25 Relypsa, Inc. Linear polyol stabilized polyfluoroacrylate compositions
WO2010129581A1 (en) * 2009-05-04 2010-11-11 Intezyne Technologies, Incorporated Polymer micelles containing sn-38 for the treatment of cancer
ES3059226T3 (en) 2012-10-08 2026-03-19 Vifor Int Ltd Potassium-binding agents for treating hypertension and hyperkalemia
JP2015101613A (ja) * 2013-11-22 2015-06-04 センカ株式会社 油溶性化合物内包水分散型高分子微粒子とその水分散体製造方法
EP2942348B1 (de) 2014-05-07 2017-10-25 Johannes Gutenberg-Universität Mainz Thiol-geschützte Aminosäurederivate und ihre Verwendungen
KR102071511B1 (ko) * 2015-11-27 2020-01-30 (주)아모레퍼시픽 미세 왁스 입자를 포함하는 유화 화장료 조성물 및 그 제조방법
JP2026108003A (ja) * 2024-12-18 2026-06-30 キヤノン株式会社 色素含有樹脂粒子、検体検査用粒子、検体検査試薬、標的物質の検査キット、色素含有樹脂粒子の製造方法、検体検査用粒子の製造方法、標的物質の検出方法
JP2026108007A (ja) * 2024-12-18 2026-06-30 キヤノン株式会社 色素含有樹脂粒子、検体検査用粒子、検体検査試薬、標的物質の検査キット、色素含有樹脂粒子の製造方法、検体検査用粒子の製造方法、標的物質の検出方法

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JPH05262809A (ja) * 1992-03-19 1993-10-12 Konica Corp 着色重合体粒子及びその製造方法
JPH10195152A (ja) * 1996-12-27 1998-07-28 Kazunori Kataoka コア−シエル型ミクロスフイアーおよびその製造方法
CN1207810A (zh) * 1995-11-22 1999-02-10 阿比翁参股及管理股份有限公司 一种耐贮藏的微粒,特别是一种用于载体结合反应的载体及其生产方法
JP2001066312A (ja) * 1999-08-25 2001-03-16 Bio Meito:Kk 診断試薬用着色ラテックス
WO2001032230A2 (en) * 1999-11-04 2001-05-10 Kazunori Kataoka A polymer micelle as monolayer or layer-laminated surface

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JP2001208754A (ja) 2000-01-26 2001-08-03 Kazunori Kataoka 生物学的な被検体を検出するための組成物
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Patent Citations (5)

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JPH05262809A (ja) * 1992-03-19 1993-10-12 Konica Corp 着色重合体粒子及びその製造方法
CN1207810A (zh) * 1995-11-22 1999-02-10 阿比翁参股及管理股份有限公司 一种耐贮藏的微粒,特别是一种用于载体结合反应的载体及其生产方法
JPH10195152A (ja) * 1996-12-27 1998-07-28 Kazunori Kataoka コア−シエル型ミクロスフイアーおよびその製造方法
JP2001066312A (ja) * 1999-08-25 2001-03-16 Bio Meito:Kk 診断試薬用着色ラテックス
WO2001032230A2 (en) * 1999-11-04 2001-05-10 Kazunori Kataoka A polymer micelle as monolayer or layer-laminated surface

Also Published As

Publication number Publication date
EP1398635A1 (de) 2004-03-17
ATE423970T1 (de) 2009-03-15
JP4167975B2 (ja) 2008-10-22
EP1398635A4 (de) 2004-12-22
US6881484B2 (en) 2005-04-19
CN1618019A (zh) 2005-05-18
KR20040010667A (ko) 2004-01-31
JPWO2002097436A1 (ja) 2004-09-16
WO2002097436A1 (fr) 2002-12-05
DE60231301D1 (de) 2009-04-09
EP1398635B1 (de) 2009-02-25
US20040171771A1 (en) 2004-09-02

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Owner name: MITSUBISHI CHEMICAL SAFETY INSTITUTE LTD.

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Co-patentee after: Nanokaria K. K.

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