CN1299116C - 封入信号产生物质的芯－壳型粒子及其制造方法 - Google Patents

封入信号产生物质的芯－壳型粒子及其制造方法 Download PDF

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Publication number
CN1299116C
CN1299116C CNB028111001A CN02811100A CN1299116C CN 1299116 C CN1299116 C CN 1299116C CN B028111001 A CNB028111001 A CN B028111001A CN 02811100 A CN02811100 A CN 02811100A CN 1299116 C CN1299116 C CN 1299116C
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China
Prior art keywords
signal
core
group
generating substance
shell
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Expired - Fee Related
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CNB028111001A
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English (en)
Chinese (zh)
Other versions
CN1618019A (zh
Inventor
片冈一则
长崎幸夫
柴田直哉
星野信广
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nanokaria K K
Mitsubishi Chemical Safety Institute Ltd
Original Assignee
Nanokaria K K
Mitsubishi Kagaku Medical Inc
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Publication of CN1618019A publication Critical patent/CN1618019A/zh
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S525/00—Synthetic resins or natural rubbers -- part of the class 520 series
    • Y10S525/902—Core-shell
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated
    • Y10T428/2998—Coated including synthetic resin or polymer

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
CNB028111001A 2001-05-30 2002-05-30 封入信号产生物质的芯－壳型粒子及其制造方法 Expired - Fee Related CN1299116C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP161787/2001 2001-05-30
JP2001161787 2001-05-30

Publications (2)

Publication Number Publication Date
CN1618019A CN1618019A (zh) 2005-05-18
CN1299116C true CN1299116C (zh) 2007-02-07

Family

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CNB028111001A Expired - Fee Related CN1299116C (zh) 2001-05-30 2002-05-30 封入信号产生物质的芯－壳型粒子及其制造方法

Country Status (8)

Country Link
US (1) US6881484B2 (de)
EP (1) EP1398635B1 (de)
JP (1) JP4167975B2 (de)
KR (1) KR20040010667A (de)
CN (1) CN1299116C (de)
AT (1) ATE423970T1 (de)
DE (1) DE60231301D1 (de)
WO (1) WO2002097436A1 (de)

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JP4355190B2 (ja) * 2003-10-10 2009-10-28 独立行政法人科学技術振興機構 生物学的被検体の高速検出方法
AU2004286253A1 (en) * 2003-10-28 2005-05-12 Bioarray Solutions Ltd. Gel-shell beads with adsorbed or bound biomolecules
US7335795B2 (en) 2004-03-22 2008-02-26 Ilypsa, Inc. Crosslinked amine polymers
US7449605B2 (en) * 2003-11-03 2008-11-11 Ilypsa, Inc. Crosslinked amine polymers
US7608674B2 (en) 2003-11-03 2009-10-27 Ilypsa, Inc. Pharmaceutical compositions comprising cross-linked small molecule amine polymers
JPWO2005073370A1 (ja) * 2004-01-31 2008-01-10 株式会社トランスパレント 酵素複合体
US7429394B2 (en) * 2004-03-30 2008-09-30 Relypsa, Inc. Ion binding compositions
US8192758B2 (en) 2004-03-30 2012-06-05 Relypsa, Inc. Ion binding compositions
US8282960B2 (en) * 2004-03-30 2012-10-09 Relypsa, Inc. Ion binding compositions
BRPI0509365B8 (pt) * 2004-03-30 2021-05-25 Ilypsa Inc composição farmacêutica, kit farmacêutico, e, uso da referida composição
US7556799B2 (en) * 2004-03-30 2009-07-07 Relypsa, Inc. Ion binding polymers and uses thereof
US7854924B2 (en) * 2004-03-30 2010-12-21 Relypsa, Inc. Methods and compositions for treatment of ion imbalances
KR101088579B1 (ko) 2004-10-04 2011-12-05 재단법인서울대학교산학협력재단 젤 타입의 코어-쉘 수지
MX2007012157A (es) 2005-04-01 2008-03-14 Intezyne Technologies Llc Micelas polimericas para suministro de farmacos.
WO2007041569A1 (en) 2005-09-30 2007-04-12 Ilypsa, Inc. Methods and compositions for selectively removing potassium ion from the gastrointestinal tract of a mammal
BRPI0616603A2 (pt) * 2005-09-30 2012-12-25 Ilypsa Inc mÉtodo para preparar um compàsito de nécleo-envoltàrio, e para a manufatura de um medicamento, composiÇço farmacÊutica, e, uso da mesma
JP2007146149A (ja) * 2005-11-02 2007-06-14 Fujifilm Corp 蛍光性重合体微粒子、蛍光性重合体微粒子の製造方法、蛍光検出キット及び蛍光検出方法
MY147967A (en) * 2006-07-31 2013-02-28 Topchim N V Particle in the shape of an encapsulated droplet and process for making such a particle.
TWI325025B (en) * 2006-09-14 2010-05-21 Taiwan Textile Res Inst Ph-adjustable fabric made by adding amphoteric polymer composite nanoparticles
JP2008074892A (ja) * 2006-09-19 2008-04-03 Fujifilm Corp 蛍光性重合体微粒子セット、蛍光検出用複合体セット、蛍光性重合体微粒子組成物及び蛍光検出方法
WO2010022381A1 (en) * 2008-08-22 2010-02-25 Relypsa, Inc. Treating hyperkalemia with crosslinked cation exchange polymers of improved physical properties
US8337824B2 (en) 2008-08-22 2012-12-25 Relypsa, Inc. Linear polyol stabilized polyfluoroacrylate compositions
PT2365988E (pt) * 2008-08-22 2015-10-22 Relypsa Inc Polímeros de permuta iónica reticulados, composições e uso no tratamento da hipercalemia
CA2760771A1 (en) * 2009-05-04 2010-11-11 Intezyne Technologies, Incorporated Polymer micelles containing sn-38 for the treatment of cancer
KR20210005314A (ko) 2012-10-08 2021-01-13 리립사, 인크. 고혈압 및 고칼륨혈증을 치료하기 위한 칼륨-결합제
JP2015101613A (ja) * 2013-11-22 2015-06-04 センカ株式会社 油溶性化合物内包水分散型高分子微粒子とその水分散体製造方法
EP2942348B1 (de) 2014-05-07 2017-10-25 Johannes Gutenberg-Universität Mainz Thiol-geschützte Aminosäurederivate und ihre Verwendungen
KR102071511B1 (ko) * 2015-11-27 2020-01-30 (주)아모레퍼시픽 미세 왁스 입자를 포함하는 유화 화장료 조성물 및 그 제조방법

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JPH05262809A (ja) * 1992-03-19 1993-10-12 Konica Corp 着色重合体粒子及びその製造方法
JPH10195152A (ja) * 1996-12-27 1998-07-28 Kazunori Kataoka コア−シエル型ミクロスフイアーおよびその製造方法
CN1207810A (zh) * 1995-11-22 1999-02-10 阿比翁参股及管理股份有限公司 一种耐贮藏的微粒,特别是一种用于载体结合反应的载体及其生产方法
JP2001066312A (ja) * 1999-08-25 2001-03-16 Bio Meito:Kk 診断試薬用着色ラテックス
WO2001032230A2 (en) * 1999-11-04 2001-05-10 Kazunori Kataoka A polymer micelle as monolayer or layer-laminated surface

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US10A (en) * 1836-08-10 Bariah Swift Dye-wood and dye-stuff cutting and shaving machine
US2002A (en) * 1841-03-12 Tor and planter for plowing
US2000A (en) * 1841-03-12 Improvement in the manufacture of starch
US5A (en) * 1836-08-10 Thomas Blanchard Machine for mortising solid wooden shells of ships' tackle-blocks
US2001A (en) * 1841-03-12 Sawmill
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IE60710B1 (en) 1987-08-26 1994-08-10 Rohm & Haas Process for microencapsulation, uses of polymers prepared by said process, and compositions containing polymers prepared by said process
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SI9620067A (sl) 1995-04-19 1998-06-30 Kazunori Kataoka Heteroteleheličen blok-kopolimer in postopek za njegovo proizvodnjo
JP2001208754A (ja) 2000-01-26 2001-08-03 Kazunori Kataoka 生物学的な被検体を検出するための組成物
JP2001324507A (ja) 2000-05-18 2001-11-22 Nano Career Kk イムノナノスフェアーを含有する免疫測定用組成物
JP2002080903A (ja) 2000-09-08 2002-03-22 Japan Science & Technology Corp 分散安定化機能性金族微粒子及び半導体微粒子およびその製造方法

Patent Citations (5)

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Publication number Priority date Publication date Assignee Title
JPH05262809A (ja) * 1992-03-19 1993-10-12 Konica Corp 着色重合体粒子及びその製造方法
CN1207810A (zh) * 1995-11-22 1999-02-10 阿比翁参股及管理股份有限公司 一种耐贮藏的微粒,特别是一种用于载体结合反应的载体及其生产方法
JPH10195152A (ja) * 1996-12-27 1998-07-28 Kazunori Kataoka コア−シエル型ミクロスフイアーおよびその製造方法
JP2001066312A (ja) * 1999-08-25 2001-03-16 Bio Meito:Kk 診断試薬用着色ラテックス
WO2001032230A2 (en) * 1999-11-04 2001-05-10 Kazunori Kataoka A polymer micelle as monolayer or layer-laminated surface

Also Published As

Publication number Publication date
US6881484B2 (en) 2005-04-19
JP4167975B2 (ja) 2008-10-22
WO2002097436A1 (fr) 2002-12-05
ATE423970T1 (de) 2009-03-15
EP1398635B1 (de) 2009-02-25
US20040171771A1 (en) 2004-09-02
JPWO2002097436A1 (ja) 2004-09-16
EP1398635A1 (de) 2004-03-17
DE60231301D1 (de) 2009-04-09
CN1618019A (zh) 2005-05-18
KR20040010667A (ko) 2004-01-31
EP1398635A4 (de) 2004-12-22

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SE01 Entry into force of request for substantive examination
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Owner name: MITSUBISHI CHEMICAL SAFETY INSTITUTE LTD.

Free format text: FORMER OWNER: MITSUBISHI KAGAKU MEDICAL, INC

Effective date: 20101222

C41 Transfer of patent application or patent right or utility model
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Effective date of registration: 20101222

Address after: Tokyo, Japan, Japan

Co-patentee after: Nanokaria K. K.

Patentee after: Mitsubishi Chemical Safety Institute Ltd.

Address before: Tokyo, Japan, Japan

Co-patentee before: Nanokaria K. K.

Patentee before: Mitsubishi Kagaku Medical, INC

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CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20070207

Termination date: 20120530