CN1425025A - 作为抗菌剂的新颖的脂肽 - Google Patents

作为抗菌剂的新颖的脂肽 Download PDF

Info

Publication number: CN1425025A
Authority: CN; China
Prior art keywords: alkyl; heteroaryl; aryl; cycloalkyl; heterocyclyl
Prior art date: 1999-12-15
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

CN00818471A

Other languages

English (en)

Chinese (zh)

Inventor

J·赫尔

I·帕尔

M·莫利特克

J·斯德勒克

喻向阳

J·斯尔沃曼

D·凯瑟

J·费恩

D·克瑞斯滕森

T·拉扎罗瓦

A·D·沃特森

张艳

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Cubist Pharmaceuticals LLC

Original Assignee

Cubist Pharmaceuticals LLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-12-15

Filing date

2000-12-15

Publication date

2003-06-18

2000-12-15 Application filed by Cubist Pharmaceuticals LLC filed Critical Cubist Pharmaceuticals LLC

2003-06-18 Publication of CN1425025A publication Critical patent/CN1425025A/zh

Status Pending legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Urology & Nephrology (AREA)
Physical Education & Sports Medicine (AREA)
Heart & Thoracic Surgery (AREA)
Pulmonology (AREA)
Cardiology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

CN00818471A 1999-12-15 2000-12-15 作为抗菌剂的新颖的脂肽 Pending CN1425025A (zh)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US17094399P	1999-12-15	1999-12-15
US60/170,943		1999-12-15

Publications (1)

Publication Number	Publication Date
CN1425025A true CN1425025A (zh)	2003-06-18

Family

ID=22621910

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CN00818471A Pending CN1425025A (zh)	1999-12-15	2000-12-15	作为抗菌剂的新颖的脂肽

Country Status (13)

Country	Link
US (2)	US6911525B2 (2)
EP (4)	EP2298790A1 (2)
JP (2)	JP4990456B2 (2)
KR (1)	KR20020063227A (2)
CN (1)	CN1425025A (2)
AU (1)	AU784755B2 (2)
BR (1)	BR0017026A (2)
CA (1)	CA2393907A1 (2)
IL (2)	IL150223A0 (2)
MX (1)	MXPA02006029A (2)
NO (1)	NO20022888L (2)
WO (1)	WO2001044272A2 (2)
ZA (1)	ZA200205106B (2)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN102939301A (zh) *	2010-03-10	2013-02-20	巴塞罗那大学	作为抗菌剂使用的肽化合物
CN110577581A (zh) *	2018-06-07	2019-12-17	美国蓝博药业公司	一种新型的抑菌脂肽化合物、制备方法及其应用
CN113061164A (zh) *	2021-03-29	2021-07-02	四川大学	环脂肽类化合物及其在抗类风湿关节炎药物中的应用

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WO2001044274A1 (en) *	1999-12-15	2001-06-21	Cubist Pharmaceuticals, Inc.	Lipopeptides as antibacterial agents
US6696412B1 (en)	2000-01-20	2004-02-24	Cubist Pharmaceuticals, Inc.	High purity lipopeptides, Lipopeptide micelles and processes for preparing same
CA2301336A1 (en) *	2000-03-17	2001-09-17	Michael T. Kelly	Topical treatment of rosacea
IL156394A0 (en)	2000-12-18	2004-01-04	Cubist Pharm Inc	Methods for preparing purified lipopeptides
US20060014674A1 (en)	2000-12-18	2006-01-19	Dennis Keith	Methods for preparing purified lipopeptides
EP1932853A1 (en)	2001-08-06	2008-06-18	Cubist Pharmaceutical Inc.	Novel depsipeptides and process for preparing same
RU2348647C2 (ru) *	2001-08-06	2009-03-10	Кьюбист Фармасьютикалз, Инк	Новые депсипептиды и способы их получения
US20030073648A1 (en) *	2001-08-28	2003-04-17	Chao Robert S.	Crystaline clindamycin free base
US6767718B2 (en)	2002-05-10	2004-07-27	Biosource Pharm, Inc.	Lipodepsipeptide antibiotics and methods of preparation
EP1531828A4 (en) *	2002-05-23	2005-11-02	Activbiotics Inc	METHODS OF TREATING BACTERIAL INFECTIONS AND ASSOCIATED DISEASES
US7317001B2 (en)	2002-06-06	2008-01-08	Oscient Pharmaceuticals Corporation	Use of ramoplanin to treat diseases associated with the use of antibiotics
IL150907A (en) *	2002-07-25	2007-07-04	Stephan Cherkez	Process for the preparation of stable amorphous calcium pseudomonate
ITMI20022076A1 (it) *	2002-10-01	2004-04-02	Antibioticos Spa	Sali di intermedi del cefdinir.
US20040132764A1 (en) *	2002-10-23	2004-07-08	Morphochem Aktiengesellschaft Fuer Kombinatorische Chemie	Antibiotics for the treatment of infections in acidic environments
US20060004185A1 (en)	2004-07-01	2006-01-05	Leese Richard A	Peptide antibiotics and peptide intermediates for their prepartion
WO2006110185A2 (en) *	2004-11-12	2006-10-19	Cubist Pharmaceuticals, Inc.	Antiinfective lipopeptides
US20080051326A1 (en) *	2004-11-12	2008-02-28	Alexander Dylan C	Antiinfective Lipopeptides
EP2974718A1 (en) *	2005-04-29	2016-01-20	Cubist Pharmaceuticals, Inc.	Therapeutic compositions
US20100227918A1 (en) *	2006-04-26	2010-09-09	Taro Pharmaceuticals North America, Inc.	Streptomyces-derived antimicrobial compound and method of using same against antibiotic-resistant bacteria
US20090311258A1 (en) *	2006-08-02	2009-12-17	Johannes Gutenberg-Universitaet Mainz	Medicament for lct poisoning
US20080185010A1 (en) *	2007-02-06	2008-08-07	Kesselman Joshua D	Interleaved Transparent Cellulose Paper with Opaque Adhesive
US8584854B2 (en) *	2007-02-06	2013-11-19	BBK Tobacco & Foods, LLP	Reclosable package with magnetic clasp and detachable tray for rolling papers used in smoking articles
US8662086B2 (en)	2007-02-06	2014-03-04	BBK Tobacco & Foods, LLP	Reclosable package with magnetic clasp for rolling papers used in smoking articles
US20090020443A1 (en) *	2007-05-09	2009-01-22	Kesselman Joshua D	Credit Card Carrying Pack for Rolling Papers
US9161572B2 (en) *	2007-06-15	2015-10-20	Bbk Tobacco & Foods, Inc.	Structures for creating smoking articles and methods of packaging same
US9072319B2 (en)	2007-06-15	2015-07-07	Joshua D. Kesselman	Rolling paper structures for creating smoking articles and gummed, coiled inserts for same
US20090014342A1 (en) *	2007-07-14	2009-01-15	Kesselman Joshua D	Rolling papers and methods of packaging same
EP2018864A1 (en)	2007-07-23	2009-01-28	Biomet Deutschland GmbH	Pharmaceutical composition, substrate comprising a pharmaceutical composition, and use of a pharmaceutical composition
CA2710602A1 (en) *	2007-12-26	2009-07-09	Lead Therapeutics, Inc.	Novel semi-synthetic glycopeptides as antibacterial agents
US8393332B2 (en)	2008-08-21	2013-03-12	BBK Tobacco & Foods, LLP	Packaging for rolling papers for smoking articles
USD606858S1 (en)	2008-08-21	2009-12-29	Joshua Kesselman	Packaging for smoking articles
GB2465863A (en) *	2008-12-05	2010-06-09	Lead Therapeutics Inc	Semi-synthetic heptapeptidic glycopeptides for the treatment of bacterial infections
BRPI0923567A2 (pt) *	2008-12-22	2016-09-27	Cubist Pharm Inc	agentes antibactericidas novos para o tratamento de infecções gram positivas
TW201035111A (en)	2008-12-23	2010-10-01	Biosource Pharm Inc	Antibiotic compositions for the treatment of gram negative infections
US8415307B1 (en)	2010-06-23	2013-04-09	Biosource Pharm, Inc.	Antibiotic compositions for the treatment of gram negative infections
WO2012011917A1 (en) *	2010-07-23	2012-01-26	Activbiotics Pharma, Llc	Administration of rifalazil to immunocompromised patients
US10072045B1 (en)	2017-06-26	2018-09-11	Ramapo Pharmaceuticals, Inc.	Antibacterial lipopeptides and methods for their preparation and use
US10526343B2 (en)	2018-03-26	2020-01-07	University Of Sharjah	Heterocyclic systems and pharmaceutical applications thereof
CN109182563B (zh) *	2018-08-01	2020-07-14	浙江大学	检测20种dfrA类甲氧苄胺嘧啶类药物耐药基因的方法及所用试剂盒

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IL68700A0 (en) *	1982-05-21	1983-09-30	Lilly Co Eli	Improvements relating to a-21978c cyclic peptide derivatives and their production
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SU1452484A3 (ru)	1984-10-09	1989-01-15	Эли Лилли Энд Компани (Фирма)	Способ получени производных антибиотиков А-21978С, штамм стрептомицета SтRертомYсеS RoSeoSpoRUS, используемый дл получени антибиотических веществ А-21978С
ZA883887B (en)	1987-06-10	1990-02-28	Lilly Co Eli	Chromatographic purification process
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ES2089133T3 (es)	1990-06-07	1996-10-01	Lilly Co Eli	Desacilasa de lipopeptidos.
JPH04167172A (ja)	1990-10-31	1992-06-15	Nec Corp	ベクトルプロセッサ
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US9393093B2 (en)	2008-02-18	2016-07-19	Covidien Lp	Clip for implant deployment device
KR20220135825A (ko)	2021-03-31	2022-10-07	에스케이하이닉스 주식회사	반도체 장치 제조 방법

2000
- 2000-12-15 CN CN00818471A patent/CN1425025A/zh active Pending
- 2000-12-15 EP EP10182947A patent/EP2298790A1/en not_active Withdrawn
- 2000-12-15 AU AU22682/01A patent/AU784755B2/en not_active Ceased
- 2000-12-15 CA CA002393907A patent/CA2393907A1/en not_active Abandoned
- 2000-12-15 WO PCT/US2000/034118 patent/WO2001044272A2/en not_active Ceased
- 2000-12-15 EP EP00986444A patent/EP1240181A2/en not_active Withdrawn
- 2000-12-15 EP EP07022686A patent/EP1884520A3/en not_active Withdrawn
- 2000-12-15 US US09/738,742 patent/US6911525B2/en not_active Expired - Lifetime
- 2000-12-15 KR KR1020027007665A patent/KR20020063227A/ko not_active Withdrawn
- 2000-12-15 IL IL15022300A patent/IL150223A0/xx unknown
- 2000-12-15 MX MXPA02006029A patent/MXPA02006029A/es unknown
- 2000-12-15 EP EP10182938A patent/EP2295444A3/en not_active Withdrawn
- 2000-12-15 BR BR0017026-7A patent/BR0017026A/pt not_active Application Discontinuation
- 2000-12-15 JP JP2001544761A patent/JP4990456B2/ja not_active Expired - Fee Related
2002
- 2002-06-13 IL IL150223A patent/IL150223A/en not_active IP Right Cessation
- 2002-06-17 NO NO20022888A patent/NO20022888L/no not_active Application Discontinuation
- 2002-06-25 ZA ZA200205106A patent/ZA200205106B/xx unknown
2005
- 2005-05-04 US US11/121,851 patent/US7335725B2/en not_active Expired - Fee Related
2012
- 2012-01-27 JP JP2012015294A patent/JP2012140432A/ja active Pending

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN102939301A (zh) *	2010-03-10	2013-02-20	巴塞罗那大学	作为抗菌剂使用的肽化合物
CN110577581A (zh) *	2018-06-07	2019-12-17	美国蓝博药业公司	一种新型的抑菌脂肽化合物、制备方法及其应用
CN113061164A (zh) *	2021-03-29	2021-07-02	四川大学	环脂肽类化合物及其在抗类风湿关节炎药物中的应用
CN113061164B (zh) *	2021-03-29	2023-01-10	四川大学	环脂肽类化合物及其在抗类风湿关节炎药物中的应用

Also Published As

Publication number	Publication date
ZA200205106B (en)	2003-09-25
NO20022888D0 (no)	2002-06-17
EP2298790A1 (en)	2011-03-23
JP2012140432A (ja)	2012-07-26
KR20020063227A (ko)	2002-08-01
BR0017026A (pt)	2003-01-07
AU2268201A (en)	2001-06-25
IL150223A (en)	2013-09-30
MXPA02006029A (es)	2004-08-23
EP1884520A2 (en)	2008-02-06
WO2001044272A3 (en)	2001-11-29
JP2003517004A (ja)	2003-05-20
US6911525B2 (en)	2005-06-28
IL150223A0 (en)	2002-12-01
EP1884520A3 (en)	2008-03-05
US20020025924A1 (en)	2002-02-28
EP2295444A3 (en)	2011-03-23
NO20022888L (no)	2002-08-02
US7335725B2 (en)	2008-02-26
CA2393907A1 (en)	2001-06-21
EP1240181A2 (en)	2002-09-18
EP2295444A2 (en)	2011-03-16
AU784755B2 (en)	2006-06-08
US20050203006A1 (en)	2005-09-15
JP4990456B2 (ja)	2012-08-01
WO2001044272A2 (en)	2001-06-21

Legal Events

Date	Code	Title
2003-06-18	C06	Publication
2003-06-18	PB01	Publication
2003-12-17	C02	Deemed withdrawal of patent application after publication (patent law 2001)
2003-12-17	WD01	Invention patent application deemed withdrawn after publication

Publication	Publication Date	Title
CN1425025A (zh)	2003-06-18	作为抗菌剂的新颖的脂肽
CN1423656A (zh)	2003-06-11	作为抗菌剂的脂肽
CN1423655A (zh)	2003-06-11	作为抗菌剂的新颖的脂肽
CN1551887A (zh)	2004-12-01	新颖的缩肽和制备它们的方法
CN1088456C (zh)	2002-07-31	取代的噁唑烷需钙蛋白酶和/或组织蛋白酶b抑制剂
CN1251041A (zh)	2000-04-19	精细调节的protegrin
CN1597698A (zh)	2005-03-23	阳离子抗菌肽
HK1155465A (en)	2012-05-18	Daptomycin analogs as antibacterial agents
HK1112926A (en)	2008-09-19	Daptomycin analogs as antibacterial agents
HK1156040A (en)	2012-06-01	Lipopeptides as antibacterial agents