CN1694889A - 用于调节lgE和抑制细胞增殖的苯基－氮杂－苯并咪唑化合物 - Google Patents

用于调节lgE和抑制细胞增殖的苯基－氮杂－苯并咪唑化合物 Download PDF

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Publication number
CN1694889A
CN1694889A CNA038250934A CN03825093A CN1694889A CN 1694889 A CN1694889 A CN 1694889A CN A038250934 A CNA038250934 A CN A038250934A CN 03825093 A CN03825093 A CN 03825093A CN 1694889 A CN1694889 A CN 1694889A
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China
Prior art keywords
substituted
group
alkyl
heteroaryl
phenyl
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Pending
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CNA038250934A
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English (en)
Chinese (zh)
Inventor
伽各蒂施·C·索卡
理查德·J·托马斯
马克·L·理查德斯
安加纳·辛哈
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Avanir Pharmaceuticals Inc
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Avanir Pharmaceuticals Inc
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Publication of CN1694889A publication Critical patent/CN1694889A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D515/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D515/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D515/04—Ortho-condensed systems

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CNA038250934A 2002-09-12 2003-09-12 用于调节lgE和抑制细胞增殖的苯基－氮杂－苯并咪唑化合物 Pending CN1694889A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41076102P 2002-09-12 2002-09-12
US60/410,761 2002-09-12

Publications (1)

Publication Number Publication Date
CN1694889A true CN1694889A (zh) 2005-11-09

Family

ID=31994198

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA038250934A Pending CN1694889A (zh) 2002-09-12 2003-09-12 用于调节lgE和抑制细胞增殖的苯基－氮杂－苯并咪唑化合物

Country Status (17)

Country Link
US (1) US7256287B2 (2)
EP (1) EP1546157A4 (2)
JP (1) JP2006503048A (2)
KR (1) KR20050050102A (2)
CN (1) CN1694889A (2)
AR (1) AR041252A1 (2)
AU (1) AU2003279729A1 (2)
BR (1) BR0314235A (2)
CA (1) CA2498495A1 (2)
MX (1) MXJL05000010A (2)
NZ (1) NZ538547A (2)
PE (1) PE20050036A1 (2)
PL (1) PL375811A1 (2)
RU (1) RU2005109911A (2)
TW (1) TWI276631B (2)
WO (1) WO2004024897A2 (2)
ZA (1) ZA200502738B (2)

Cited By (2)

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CN103819398A (zh) * 2014-01-24 2014-05-28 河北科技大学 4-氨基-2-氯-3-硝基吡啶的合成方法
CN117924278A (zh) * 2024-01-19 2024-04-26 四川大学 一种二胺单体、聚酰亚胺聚合物、芳香族聚酰胺聚合物及其制备方法和用途

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CN103819398A (zh) * 2014-01-24 2014-05-28 河北科技大学 4-氨基-2-氯-3-硝基吡啶的合成方法
CN103819398B (zh) * 2014-01-24 2016-05-04 河北科技大学 4-氨基-2-氯-3-硝基吡啶的合成方法
CN117924278A (zh) * 2024-01-19 2024-04-26 四川大学 一种二胺单体、聚酰亚胺聚合物、芳香族聚酰胺聚合物及其制备方法和用途

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