CN1867310B - 促进毛发生长的组合物及其用途 - Google Patents

促进毛发生长的组合物及其用途 Download PDF

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Publication number
CN1867310B
CN1867310B CN2004800298049A CN200480029804A CN1867310B CN 1867310 B CN1867310 B CN 1867310B CN 2004800298049 A CN2004800298049 A CN 2004800298049A CN 200480029804 A CN200480029804 A CN 200480029804A CN 1867310 B CN1867310 B CN 1867310B
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CN
China
Prior art keywords
compound
alkyl
ethyl
dihydro
saturated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN2004800298049A
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English (en)
Chinese (zh)
Other versions
CN1867310A (zh
Inventor
上野隆司
波部豪
关田隆
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
R Tech Ueno Ltd
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Sucampo GmbH
Co Ltd R Tech Ueno
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34135320&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN1867310(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sucampo GmbH, Co Ltd R Tech Ueno filed Critical Sucampo GmbH
Publication of CN1867310A publication Critical patent/CN1867310A/zh
Application granted granted Critical
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Anticipated expiration legal-status Critical
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN2004800298049A 2003-08-12 2004-08-12 促进毛发生长的组合物及其用途 Expired - Fee Related CN1867310B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US49412103P 2003-08-12 2003-08-12
US60/494,121 2003-08-12
PCT/JP2004/011864 WO2005013928A1 (fr) 2003-08-12 2004-08-12 Composition et methode pour favoriser la croissance capillaire

Publications (2)

Publication Number Publication Date
CN1867310A CN1867310A (zh) 2006-11-22
CN1867310B true CN1867310B (zh) 2010-06-16

Family

ID=34135320

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2004800298049A Expired - Fee Related CN1867310B (zh) 2003-08-12 2004-08-12 促进毛发生长的组合物及其用途

Country Status (15)

Country Link
US (2) US8686035B2 (fr)
EP (2) EP1673058B1 (fr)
JP (2) JP4642021B2 (fr)
KR (3) KR101166738B1 (fr)
CN (1) CN1867310B (fr)
AT (1) ATE526008T1 (fr)
CA (1) CA2534645C (fr)
CY (1) CY1112076T1 (fr)
DK (1) DK1673058T3 (fr)
ES (1) ES2369892T3 (fr)
PL (1) PL1673058T3 (fr)
PT (1) PT1673058E (fr)
SI (1) SI1673058T1 (fr)
TW (2) TWI495471B (fr)
WO (1) WO2005013928A1 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI495471B (zh) 2003-08-12 2015-08-11 R Tech Ueno Ltd 促進毛髮生長之組成物及方法
WO2006070942A1 (fr) 2004-12-29 2006-07-06 R-Tech Ueno, Ltd Preparation et methode pour le traitement du cuir chevelu et des cheveux
US8455547B2 (en) * 2008-02-05 2013-06-04 Allergan, Inc. Substituted cyclopentanes having prostaglandin activity
US7964596B2 (en) * 2008-03-07 2011-06-21 Allergan, Inc. Therapeutic compounds
US7732443B2 (en) * 2008-03-18 2010-06-08 Yariv Donde Therapeutic substituted cyclopentanes
US7964599B2 (en) * 2008-05-09 2011-06-21 Allergan, Inc. Therapeutic compounds
JP5850862B2 (ja) * 2010-02-24 2016-02-03 アドヴァンジェン・インターナショナル・プロプライアタリー・リミテッド 脱毛の治療もしくは予防または毛の成長の促進のための方法
WO2012176792A1 (fr) 2011-06-21 2012-12-27 株式会社アールテック・ウエノ Composition pharmaceutique pour des maladies inflammatoires, maladies allergiques et maladies auto-immunes
US20160128926A1 (en) * 2013-05-10 2016-05-12 Topical Solutions, Inc. Compositions and methods for treating nails, claws, and hoofs
US11253518B2 (en) 2019-08-07 2022-02-22 Aneira Pharma, Inc. Methods and compositions for the treatment of hair loss
US12539302B2 (en) 2019-08-07 2026-02-03 Aneira Pharma, Inc. Methods and compositions for the treatment of hair loss

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3962218A (en) * 1973-05-30 1976-06-08 Schering Aktiengesellschaft Novel prostanoic acid derivatives and processes for the preparation thereof
US4088775A (en) * 1974-07-12 1978-05-09 Schering Aktiengesellschaft 15-Ethylenedioxy-prostanoic acid derivatives and esters thereof and intermediates thereof
EP0308135A2 (fr) * 1987-09-18 1989-03-22 R-Tech Ueno Ltd. Agents hypotenseurs ophtalmologiques
US6262105B1 (en) * 1997-02-04 2001-07-17 Murray A. Johnstone Method of enhancing hair growth
US6353014B1 (en) * 1996-11-12 2002-03-05 Alcon Laboratories, Inc. 15-ketal postaglandins for the treatment of glaucoma or ocular hypertension

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CS230650B1 (cs) 1983-01-14 1984-08-13 Jan Stanek Způsob výroby acetalů prostanoidů
DE3325175A1 (de) 1983-07-08 1985-01-17 Schering AG, 1000 Berlin und 4709 Bergkamen 11-halogen-prostanderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
JPH0818989B2 (ja) 1984-01-12 1996-02-28 株式会社ミドリ十字 脂肪乳剤中のプロスタグランジンの安定化方法
JPS61218510A (ja) * 1985-03-22 1986-09-29 Dai Ichi Seiyaku Co Ltd 毛髪用剤
US5380709A (en) 1987-01-28 1995-01-10 K.K. Ueno Seiyaku Oyo Kenkyujo Prostaglandins E and anti ulcers containing same
CA1322749C (fr) 1987-01-28 1993-10-05 Ryuzo Ueno Prostaglandines de la serie d, et tranquilisants et soporifiques en contenant
US5166174A (en) 1987-01-28 1992-11-24 K.K. Ueno Seiyaku Oyo Kenkyujo Prostaglandins E and anti-ulcers containing same
CA1324129C (fr) * 1987-04-30 1993-11-09 Ryuzo Ueno Prostaglandines de la serie f
US5221763A (en) 1987-04-30 1993-06-22 R-Tech Ueno, Ltd. Prostaglandins of the F series
US5591887A (en) 1987-04-30 1997-01-07 R-Tech Ueno, Ltd. Prostaglandins of the F series
US5166178B1 (en) 1987-09-18 1998-07-21 R Tech Ueno Ltd Ocular hypotensive agents
US5212200A (en) 1987-09-18 1993-05-18 R-Tech Ueno, Ltd. Ocular hypotensive agents
TW224942B (fr) 1990-04-04 1994-06-11 Adka Ueno Kk
ATE117208T1 (de) 1990-05-22 1995-02-15 R Tech Ueno Ltd Behandlung von intraokularem druck mit einer ophthalmischen synergistischen kombination.
US5175189A (en) 1990-05-22 1992-12-29 K.K. Ueno Seiyaku Oyo Kenkyujo Treatment of ocular hypertension with a synergistic combination for ophthalmic use
US5166175A (en) 1990-05-22 1992-11-24 K.K. Ueno Seiyaku Oyo Kenkyujo Treatment of ocular hypertension with a synergistic combination
DE69105349T2 (de) 1990-05-22 1995-04-06 Ueno Seiyaku Oyo Kenkyujo Kk Behandlung von intraocularem Druck mit einer synergistischen Kombination zur ophthalmischen Verwendung.
TW210287B (fr) 1991-03-01 1993-08-01 Kabushikaisha Ueno Seiyaku Oyo Kenkyujo
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EP0668076B1 (fr) 1992-08-26 2002-09-04 Sucampo AG Stabilisation de dérivés de l'acide prostanoique
SE9303444D0 (sv) 1993-10-20 1993-10-20 Kabi Pharmacia Ab New use of prostaglandins
SE9402816D0 (sv) 1994-08-24 1994-08-24 Pharmacia Ab Method and meams for drug administration
US6242485B1 (en) * 1996-06-10 2001-06-05 R-Tech Ueno Endothelin antagonist
AU3588797A (en) 1996-07-03 1998-01-21 Board Of Regents Of The University Of Oklahoma, The Enhancement of skin pigmentation by prostaglandins
JP3217293B2 (ja) * 1997-04-17 2001-10-09 株式会社アールテック・ウエノ 発毛・育毛剤
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US6225348B1 (en) 1998-08-20 2001-05-01 Alfred W. Paulsen Method of treating macular degeneration with a prostaglandin derivative
DE60039727D1 (de) 1999-10-15 2008-09-11 Sucampo Ag Neue Zusammensetzung enthaltend eine bicyclische Verbindung und ein Glycerid
US20020037914A1 (en) 2000-03-31 2002-03-28 Delong Mitchell Anthony Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins
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SE0100158D0 (sv) 2001-01-19 2001-01-19 Synphora Ab Novel method and composition for local treatment of Meniere´s disease and tinnitus
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JP2003155218A (ja) * 2001-09-10 2003-05-27 Lion Corp 養育毛組成物
US7351404B2 (en) 2002-02-04 2008-04-01 Allergan, Inc. Method of enhancing hair growth
US20030199590A1 (en) 2002-07-25 2003-10-23 Cagle Gerald D Prostaglandin analogues for promotion of hair growth
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WO2006070942A1 (fr) 2004-12-29 2006-07-06 R-Tech Ueno, Ltd Preparation et methode pour le traitement du cuir chevelu et des cheveux
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US20070160562A1 (en) 2006-01-06 2007-07-12 Brinkenhoff Michael C Delivery devices for hair-promoting cosmetic agent
US20070286890A1 (en) 2006-06-07 2007-12-13 John Garnett Walt Eyelash applicator and method
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WO2009035565A1 (fr) 2007-09-07 2009-03-19 Qlt Plug Delivery, Inc Analogues de prostaglandines pour des dispositifs d'implant et procédés
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WO2009054787A1 (fr) * 2007-10-26 2009-04-30 Astrazeneca Ab Dérivés d'acide 1,2,4-triazole carboxylique utilisés en tant que modulateurs de mglur5
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Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3962218A (en) * 1973-05-30 1976-06-08 Schering Aktiengesellschaft Novel prostanoic acid derivatives and processes for the preparation thereof
US4088775A (en) * 1974-07-12 1978-05-09 Schering Aktiengesellschaft 15-Ethylenedioxy-prostanoic acid derivatives and esters thereof and intermediates thereof
EP0308135A2 (fr) * 1987-09-18 1989-03-22 R-Tech Ueno Ltd. Agents hypotenseurs ophtalmologiques
US6353014B1 (en) * 1996-11-12 2002-03-05 Alcon Laboratories, Inc. 15-ketal postaglandins for the treatment of glaucoma or ocular hypertension
US6262105B1 (en) * 1997-02-04 2001-07-17 Murray A. Johnstone Method of enhancing hair growth

Also Published As

Publication number Publication date
JP2011012076A (ja) 2011-01-20
KR101166738B1 (ko) 2012-07-23
DK1673058T3 (da) 2011-10-24
JP2007518685A (ja) 2007-07-12
EP2243771A3 (fr) 2011-01-12
US20080033036A1 (en) 2008-02-07
SI1673058T1 (sl) 2011-11-30
EP1673058A1 (fr) 2006-06-28
US20140171496A1 (en) 2014-06-19
KR101137750B1 (ko) 2012-04-24
TWI495471B (zh) 2015-08-11
CY1112076T1 (el) 2015-12-09
TWI348386B (en) 2011-09-11
CN1867310A (zh) 2006-11-22
EP2243771A2 (fr) 2010-10-27
TW201039831A (en) 2010-11-16
EP1673058B1 (fr) 2011-09-28
US8686035B2 (en) 2014-04-01
PL1673058T3 (pl) 2012-02-29
ATE526008T1 (de) 2011-10-15
KR20110087351A (ko) 2011-08-02
HK1098949A1 (en) 2007-08-03
PT1673058E (pt) 2011-10-12
TW200505494A (en) 2005-02-16
KR20060058708A (ko) 2006-05-30
JP4642021B2 (ja) 2011-03-02
CA2534645A1 (fr) 2005-02-17
CA2534645C (fr) 2013-05-07
KR20120008080A (ko) 2012-01-25
JP5318837B2 (ja) 2013-10-16
ES2369892T3 (es) 2011-12-07
WO2005013928A1 (fr) 2005-02-17

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