CR10775A - Proteinas de dedo de zin no canonicas optimizadas - Google Patents
Proteinas de dedo de zin no canonicas optimizadasInfo
- Publication number
- CR10775A CR10775A CR10775A CR10775A CR10775A CR 10775 A CR10775 A CR 10775A CR 10775 A CR10775 A CR 10775A CR 10775 A CR10775 A CR 10775A CR 10775 A CR10775 A CR 10775A
- Authority
- CR
- Costa Rica
- Prior art keywords
- canonic
- finger proteins
- optimized non
- zin
- zin finger
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
- C12N15/8213—Targeted insertion of genes into the plant genome by homologous recombination
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/80—Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor
- C07K2319/81—Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor containing a Zn-finger domain for DNA binding
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nutrition Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87491106P | 2006-12-14 | 2006-12-14 | |
| US93249707P | 2007-05-30 | 2007-05-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CR10775A true CR10775A (es) | 2009-08-12 |
Family
ID=39472493
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CR10775A CR10775A (es) | 2006-12-14 | 2009-05-07 | Proteinas de dedo de zin no canonicas optimizadas |
Country Status (21)
| Country | Link |
|---|---|
| US (3) | US9187758B2 (es) |
| EP (5) | EP2092068B1 (es) |
| JP (1) | JP5632610B2 (es) |
| KR (4) | KR101574529B1 (es) |
| CN (1) | CN103613646B (es) |
| AR (1) | AR069896A1 (es) |
| AU (1) | AU2007334468B2 (es) |
| BR (1) | BRPI0720048A8 (es) |
| CA (2) | CA2669746C (es) |
| CO (1) | CO6220864A2 (es) |
| CR (1) | CR10775A (es) |
| DK (3) | DK2415872T3 (es) |
| EG (1) | EG26980A (es) |
| ES (1) | ES2586210T3 (es) |
| HU (1) | HUE029238T2 (es) |
| MX (1) | MX2009006303A (es) |
| NZ (2) | NZ597995A (es) |
| PT (4) | PT2415872T (es) |
| SI (2) | SI2092068T1 (es) |
| TW (1) | TWI470079B (es) |
| WO (1) | WO2008076290A2 (es) |
Families Citing this family (146)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY150088A (en) | 2003-05-19 | 2013-11-29 | Irm Llc | Immunosuppressant compounds and compositions |
| US9187758B2 (en) * | 2006-12-14 | 2015-11-17 | Sangamo Biosciences, Inc. | Optimized non-canonical zinc finger proteins |
| DK2205749T3 (en) | 2007-09-27 | 2016-08-22 | Dow Agrosciences Llc | MODIFIED PROTEINS zinc finger, which target the 5-enolpyruvylshikimate-3-phosphate synthase genes |
| US20100316702A1 (en) * | 2008-01-08 | 2010-12-16 | The Regents Of The University Of California | Compositions and methods for regulating erythropoeitin expression and ameliorating anemia and stimulating erythropoiesis |
| JP5763530B2 (ja) * | 2008-06-10 | 2015-08-12 | サンガモ バイオサイエンシーズ, インコーポレイテッド | Bax−およびBak−欠損細胞株の生成のための方法および組成物 |
| ES2654923T3 (es) * | 2008-12-17 | 2018-02-15 | Dow Agrosciences Llc | Integración dirigida en la localización Zp15 |
| KR20100080068A (ko) * | 2008-12-31 | 2010-07-08 | 주식회사 툴젠 | 신규한 징크 핑거 뉴클레아제 및 이의 용도 |
| EP3428289B1 (en) * | 2009-08-11 | 2020-05-20 | Sangamo Therapeutics, Inc. | Organisms homozygous for targeted modification |
| US10172669B2 (en) | 2009-10-09 | 2019-01-08 | Ethicon Llc | Surgical instrument comprising an energy trigger lockout |
| US9476060B2 (en) * | 2009-10-21 | 2016-10-25 | Danziger Innovations Ltd. | Generating genotypic variations in plant genomes by gamete infection |
| RU2712833C2 (ru) | 2009-10-22 | 2020-01-31 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Конструируемые белки с цинковыми пальцами, направленные на гены растений, вовлеченные в биосинтез жирных кислот |
| CN102639695B (zh) * | 2009-10-26 | 2015-01-21 | 独立行政法人农业生物资源研究所 | 转基因植物细胞的制造方法 |
| AR079149A1 (es) | 2009-11-24 | 2011-12-28 | Dow Agrosciences Llc | Evento 416 de aad-12, lineas de soja transgenica relacionadas y su identificacion especifica del evento |
| AU2010325549B2 (en) | 2009-11-27 | 2017-04-20 | Basf Plant Science Company Gmbh | Optimized endonucleases and uses thereof |
| JP2013511979A (ja) | 2009-11-27 | 2013-04-11 | ビーエーエスエフ プラント サイエンス カンパニー ゲーエムベーハー | キメラエンドヌクレアーゼおよびその使用 |
| WO2011064750A1 (en) | 2009-11-27 | 2011-06-03 | Basf Plant Science Company Gmbh | Chimeric endonucleases and uses thereof |
| US20110203012A1 (en) * | 2010-01-21 | 2011-08-18 | Dotson Stanton B | Methods and compositions for use of directed recombination in plant breeding |
| NZ601247A (en) * | 2010-01-22 | 2014-10-31 | Dow Agrosciences Llc | Targeted genomic alteration |
| JP6208580B2 (ja) | 2010-05-17 | 2017-10-04 | サンガモ セラピューティクス, インコーポレイテッド | 新規のdna結合タンパク質及びその使用 |
| GB2480498A (en) | 2010-05-21 | 2011-11-23 | Ethicon Endo Surgery Inc | Medical device comprising RF circuitry |
| CA2807270A1 (en) * | 2010-08-02 | 2012-02-09 | Cellectis | Method for targeted genomic events in diatoms |
| CN103561564B (zh) | 2010-12-03 | 2016-11-16 | 陶氏益农公司 | 叠加的除草剂耐受性事件8264.44.06.1、相关转基因大豆系、及其检测 |
| WO2012074868A2 (en) | 2010-12-03 | 2012-06-07 | Ms Technologies, Llc | Optimized expression of glyphosate resistance encoding nucleic acid molecules in plant cells |
| EP3375878A1 (en) | 2010-12-30 | 2018-09-19 | Dow AgroSciences LLC | Nucleic acid molecules that target the vacuolar atphase h subunit and confer resistance to coleopteran pests |
| PH12013501410A1 (en) | 2010-12-30 | 2013-08-28 | Dow Agrosciences Llc | Nucleic acid molecules that target the rho1 small gtp-binding protein and confer resistance to coleopteran pests |
| KR20130130804A (ko) | 2010-12-30 | 2013-12-02 | 다우 아그로사이언시즈 엘엘씨 | 공포 atpase c 서브유닛을 표적화하고 딱정벌레목 해충에 대한 저항성을 부여하는 핵산 분자 |
| UY34014A (es) | 2011-04-15 | 2012-11-30 | Dow Agrosciences Llc | Genes sintéticos para expresar proteínas en células de maíz, construcciones, plantas transgénicas, métodos para controlar pestes y composiciones |
| BR102012019434B1 (pt) | 2011-07-26 | 2021-11-09 | Dow Agrosciences Llc | Métodos de controle de pestes, de insetos, molécula e sequência de dna diagnóstica para o evento de soja 9582.814.19.1 |
| CN107287234A (zh) * | 2011-08-22 | 2017-10-24 | 拜尔作物科学公司 | 修饰植物基因组的方法和手段 |
| US9414880B2 (en) | 2011-10-24 | 2016-08-16 | Ethicon Endo-Surgery, Llc | User interface in a battery powered device |
| JP6144691B2 (ja) | 2011-11-16 | 2017-06-07 | サンガモ セラピューティクス, インコーポレイテッド | 修飾されたdna結合タンパク質およびその使用 |
| EP2612918A1 (en) | 2012-01-06 | 2013-07-10 | BASF Plant Science Company GmbH | In planta recombination |
| BR102013001764B1 (pt) | 2012-01-23 | 2022-03-22 | Dow Agrosciences Llc | Método de detecção do evento de algodão pdab4468.19.10.3 em uma amostra que compreende dna de algodão |
| JP6242345B2 (ja) | 2012-02-01 | 2017-12-06 | ダウ アグロサイエンシィズ エルエルシー | グリホサート抵抗性植物および関連する方法 |
| AR089877A1 (es) * | 2012-02-02 | 2014-09-24 | Dow Agrosciences Llc | Motivos de interaccion de transactivacion en plantas y sus usos |
| NZ629427A (en) | 2012-02-29 | 2016-04-29 | Sangamo Biosciences Inc | Methods and compositions for treating huntington’s disease |
| US11518997B2 (en) | 2012-04-23 | 2022-12-06 | BASF Agricultural Solutions Seed US LLC | Targeted genome engineering in plants |
| KR102091298B1 (ko) | 2012-05-02 | 2020-03-19 | 다우 아그로사이언시즈 엘엘씨 | 말산 탈수소효소의 표적화된 변형 |
| CA2871524C (en) * | 2012-05-07 | 2021-07-27 | Sangamo Biosciences, Inc. | Methods and compositions for nuclease-mediated targeted integration of transgenes |
| WO2014028378A2 (en) * | 2012-08-13 | 2014-02-20 | The Regents Of The University Of California | Methods and systems for detecting biological components |
| UA118090C2 (uk) | 2012-09-07 | 2018-11-26 | ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі | Спосіб інтегрування послідовності нуклеїнової кислоти, що представляє інтерес, у ген fad2 у клітині сої та специфічний для локусу fad2 білок, що зв'язується, здатний індукувати спрямований розрив |
| UA119135C2 (uk) * | 2012-09-07 | 2019-05-10 | ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі | Спосіб отримання трансгенної рослини |
| TWI670004B (zh) | 2012-09-07 | 2019-09-01 | 美商陶氏農業科學公司 | 用來產生植物之螢光激活細胞分選富增技術 |
| BR112015004995B1 (pt) | 2012-09-07 | 2023-05-02 | Sangamo Biosciences, Inc. | Método para modificação do genoma de uma célula, uso de uma célula, semente ou planta obtida pelo referido método e nuclease de dedo de zinco sítio específica |
| WO2014093736A1 (en) * | 2012-12-13 | 2014-06-19 | Dow Agrosciences Llc | Dna detection methods for site specific nuclease activity |
| CA2895117A1 (en) | 2012-12-13 | 2014-06-19 | James W. Bing | Precision gene targeting to a particular locus in maize |
| AU2014218931C1 (en) | 2013-02-20 | 2020-05-14 | Regeneron Pharmaceuticals, Inc. | Genetic modification of rats |
| US10501748B2 (en) | 2013-04-05 | 2019-12-10 | Dow Agrosciences Llc | Methods and compositions for integration of an exogenous sequence within the genome of plants |
| CA2908697C (en) | 2013-04-16 | 2023-12-12 | Regeneron Pharmaceuticals, Inc. | Targeted modification of rat genome |
| CA2920899C (en) | 2013-08-28 | 2023-02-28 | Sangamo Biosciences, Inc. | Compositions for linking dna-binding domains and cleavage domains |
| RU2668819C2 (ru) | 2013-09-04 | 2018-10-02 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Быстрый направленный анализ сельскохозяйственных культур для определения донорной вставки |
| WO2015066634A2 (en) | 2013-11-04 | 2015-05-07 | Dow Agrosciences Llc | Optimal soybean loci |
| EP3066110B1 (en) | 2013-11-04 | 2021-12-29 | Corteva Agriscience LLC | Optimal maize loci |
| KR102269769B1 (ko) | 2013-11-04 | 2021-06-28 | 코르테바 애그리사이언스 엘엘씨 | 최적 메이즈 유전자좌 |
| EP3066202B1 (en) | 2013-11-04 | 2021-03-03 | Dow AgroSciences LLC | Optimal soybean loci |
| PL3068881T3 (pl) * | 2013-11-13 | 2019-08-30 | Children's Medical Center Corporation | Regulacja ekspresji genów, w której pośredniczą nukleazy |
| SG10201700961TA (en) | 2013-12-11 | 2017-04-27 | Regeneron Pharma | Methods and compositions for the targeted modification of a genome |
| HUE041331T2 (hu) | 2013-12-11 | 2019-05-28 | Regeneron Pharma | Módszerek és készítmények a genom célzott módosításához |
| US10683513B2 (en) | 2013-12-31 | 2020-06-16 | Dow Agrosciences Llc | Tissue-specific expression and hybrid plant production |
| US10774338B2 (en) | 2014-01-16 | 2020-09-15 | The Regents Of The University Of California | Generation of heritable chimeric plant traits |
| HUE049776T2 (hu) | 2014-06-06 | 2020-10-28 | Regeneron Pharma | Módszerek és készítmények egy célzott lókusz módosítására |
| MX384887B (es) | 2014-06-23 | 2025-03-14 | Regeneron Pharma | Ensamblaje de adn mediado por nucleasa. |
| EP3161128B1 (en) | 2014-06-26 | 2018-09-26 | Regeneron Pharmaceuticals, Inc. | Methods and compositions for targeted genetic modifications and methods of use |
| US20170159065A1 (en) | 2014-07-08 | 2017-06-08 | Vib Vzw | Means and methods to increase plant yield |
| CA2955203C (en) | 2014-07-14 | 2022-01-04 | Washington State University | Nanos knock-out that ablates germline cells |
| WO2016037161A2 (en) | 2014-09-07 | 2016-03-10 | Selecta Biosciences, Inc. | Methods and compositions for attenuating gene editing anti-viral transfer vector immune responses |
| DK3207124T3 (da) | 2014-10-15 | 2019-08-12 | Regeneron Pharma | Fremgangsmåder og sammensætninger til generering eller bevaring af pluripotente celler |
| WO2016084084A1 (en) | 2014-11-27 | 2016-06-02 | Danziger Innovations Ltd. | Nucleic acid constructs for genome editing |
| JP6840077B2 (ja) | 2014-12-19 | 2021-03-10 | リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. | 単一ステップの複数標的化を通じた標的化された遺伝子修飾のための方法及び組成物 |
| US10159524B2 (en) | 2014-12-22 | 2018-12-25 | Ethicon Llc | High power battery powered RF amplifier topology |
| JP2018508198A (ja) | 2015-02-04 | 2018-03-29 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 別個の実体におけるバーコード付加による核酸のシーケンシング |
| US20160281055A1 (en) | 2015-03-20 | 2016-09-29 | Dow Agrosciences Llc | Incorporation of phosphatidylcholine in a media composition |
| US20180080051A1 (en) | 2015-03-31 | 2018-03-22 | Exeligen Scientific, Inc. | Cas 9 retroviral integrase and cas 9 recombinase systems for targeted incorporation of a dna sequence into a genome of a cell or organism |
| US10314638B2 (en) | 2015-04-07 | 2019-06-11 | Ethicon Llc | Articulating radio frequency (RF) tissue seal with articulating state sensing |
| EP3331355B1 (en) | 2015-08-06 | 2024-04-03 | The Curators of the University of Missouri | Porcine reproductive and respiratory syndrome virus (prrsv)-resistant porcine and cells having modified cd163 genes |
| US11606940B2 (en) | 2015-08-07 | 2023-03-21 | Commonwealth Scientific And Industrial Research Organisation | Method for producing an animal comprising a germline genetic modification |
| US10959771B2 (en) | 2015-10-16 | 2021-03-30 | Ethicon Llc | Suction and irrigation sealing grasper |
| EP3380616A4 (en) | 2015-11-24 | 2019-11-06 | Commonwealth Scientific and Industrial Research Organisation | MANUFACTURE OF VIRUSES IN BIRDS |
| CN108603188A (zh) | 2015-11-24 | 2018-09-28 | 联邦科学技术研究组织 | 在细胞培养物中产生病毒 |
| US10959806B2 (en) | 2015-12-30 | 2021-03-30 | Ethicon Llc | Energized medical device with reusable handle |
| US10856934B2 (en) | 2016-04-29 | 2020-12-08 | Ethicon Llc | Electrosurgical instrument with electrically conductive gap setting and tissue engaging members |
| US10987156B2 (en) | 2016-04-29 | 2021-04-27 | Ethicon Llc | Electrosurgical instrument with electrically conductive gap setting member and electrically insulative tissue engaging members |
| RU2721125C1 (ru) | 2016-07-29 | 2020-05-18 | Регенерон Фармасьютикалз, Инк. | Мыши, содержащие мутации, вследствие которых экспрессируется укороченный на с-конце фибриллин-1 |
| US10751117B2 (en) | 2016-09-23 | 2020-08-25 | Ethicon Llc | Electrosurgical instrument with fluid diverter |
| WO2018136758A1 (en) | 2017-01-23 | 2018-07-26 | Regeneron Pharmaceuticals, Inc. | Hsd17b13 variants and uses thereof |
| US11033325B2 (en) | 2017-02-16 | 2021-06-15 | Cilag Gmbh International | Electrosurgical instrument with telescoping suction port and debris cleaner |
| US10799284B2 (en) | 2017-03-15 | 2020-10-13 | Ethicon Llc | Electrosurgical instrument with textured jaws |
| US11497546B2 (en) | 2017-03-31 | 2022-11-15 | Cilag Gmbh International | Area ratios of patterned coatings on RF electrodes to reduce sticking |
| US11913015B2 (en) | 2017-04-17 | 2024-02-27 | University Of Maryland, College Park | Embryonic cell cultures and methods of using the same |
| US10603117B2 (en) | 2017-06-28 | 2020-03-31 | Ethicon Llc | Articulation state detection mechanisms |
| ES3038389T3 (en) | 2017-08-29 | 2025-10-13 | Kws Saat Se & Co Kgaa | Improved blue aleurone and other segregation systems |
| US11490951B2 (en) | 2017-09-29 | 2022-11-08 | Cilag Gmbh International | Saline contact with electrodes |
| US11033323B2 (en) | 2017-09-29 | 2021-06-15 | Cilag Gmbh International | Systems and methods for managing fluid and suction in electrosurgical systems |
| US11484358B2 (en) | 2017-09-29 | 2022-11-01 | Cilag Gmbh International | Flexible electrosurgical instrument |
| ES2962277T3 (es) | 2017-09-29 | 2024-03-18 | Regeneron Pharma | Roedores que comprenden un locus Ttr humanizado y métodos de uso |
| GB201716254D0 (en) * | 2017-10-05 | 2017-11-22 | Univ Leuven Kath | Live-attenuated flaviruses with heterologous antigens |
| AU2018347583A1 (en) | 2017-10-13 | 2020-05-21 | Selecta Biosciences, Inc. | Methods and compositions for attenuating anti-viral transfer vector IgM responses |
| US12178908B2 (en) | 2018-02-26 | 2024-12-31 | AnTolRx, Inc. | Tolerogenic liposomes and methods of use thereof |
| US20210037798A1 (en) | 2018-03-20 | 2021-02-11 | Tsinghua University | Alzheimers disease animal model and use thereof |
| EP3781677A4 (en) | 2018-04-16 | 2022-01-19 | University of Massachusetts | COMPOSITIONS AND METHODS FOR IMPROVED GENE EDITTING |
| WO2020036653A2 (en) * | 2018-04-25 | 2020-02-20 | The Regents Of The University Of California | Improved method for homology directed repair in cells |
| GB201809273D0 (en) | 2018-06-06 | 2018-07-25 | Vib Vzw | Novel mutant plant cinnamoyl-coa reductase proteins |
| GB201820109D0 (en) | 2018-12-11 | 2019-01-23 | Vib Vzw | Plants with a lignin trait and udp-glycosyltransferase mutation |
| US11690362B2 (en) | 2018-12-20 | 2023-07-04 | Regeneran Pharmaceuticals, Inc. | Nuclease-mediated repeat expansion |
| AU2020256225B9 (en) | 2019-04-03 | 2025-04-10 | Regeneron Pharmaceuticals, Inc. | Methods and compositions for insertion of antibody coding sequences into a safe harbor locus |
| WO2020206139A1 (en) | 2019-04-04 | 2020-10-08 | Regeneron Pharmaceuticals, Inc. | Non-human animals comprising a humanized coagulation factor 12 locus |
| US11111504B2 (en) | 2019-04-04 | 2021-09-07 | Regeneron Pharmaceuticals, Inc. | Methods for scarless introduction of targeted modifications into targeting vectors |
| CA3141159A1 (en) | 2019-05-21 | 2020-11-26 | Sangamo Therapeutics, Inc. | Controlled transgene expression in regulatory t cells |
| WO2020243261A1 (en) | 2019-05-28 | 2020-12-03 | Selecta Biosciences, Inc. | Methods and compositions for attenuated anti-viral transfer vector immune response |
| EP3801011A1 (en) | 2019-06-04 | 2021-04-14 | Regeneron Pharmaceuticals, Inc. | Non-human animals comprising a humanized ttr locus with a beta-slip mutation and methods of use |
| WO2020244759A1 (en) | 2019-06-05 | 2020-12-10 | Klemm & Sohn Gmbh & Co. Kg | New plants having a white foliage phenotype |
| AU2020289581B2 (en) | 2019-06-07 | 2024-11-21 | Regeneron Pharmaceuticals, Inc. | Non-human animals comprising a humanized albumin locus |
| CA3137765A1 (en) | 2019-06-14 | 2020-12-17 | Regeneron Pharmaceuticals, Inc. | Models of tauopathy |
| EP3987024A4 (en) | 2019-06-20 | 2023-11-01 | University Of Massachusetts | COMPOSITIONS AND METHODS FOR ENHANCED GENOMIC EDITING |
| WO2021022043A2 (en) | 2019-07-30 | 2021-02-04 | Pairwise Plants Services, Inc. | Morphogenic regulators and methods of using the same |
| WO2021028359A1 (en) | 2019-08-09 | 2021-02-18 | Sangamo Therapeutics France | Controlled expression of chimeric antigen receptors in t cells |
| AU2020379046B2 (en) | 2019-11-08 | 2025-03-13 | Regeneron Pharmaceuticals, Inc. | CRISPR and AAV strategies for X-linked juvenile retinoschisis therapy |
| WO2021108363A1 (en) | 2019-11-25 | 2021-06-03 | Regeneron Pharmaceuticals, Inc. | Crispr/cas-mediated upregulation of humanized ttr allele |
| JP2023515671A (ja) | 2020-03-04 | 2023-04-13 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | 免疫療法に対する腫瘍細胞の感作のための方法及び組成物 |
| WO2021191870A1 (en) | 2020-03-27 | 2021-09-30 | Dcprime B.V. | Ex vivo use of modified cells of leukemic origin for enhancing the efficacy of adoptive cell therapy |
| JP2023531537A (ja) | 2020-06-30 | 2023-07-24 | メンドゥス・ベスローテン・フェンノートシャップ | 卵巣癌ワクチンでの白血病由来細胞の使用 |
| MX2023005665A (es) | 2020-11-16 | 2023-08-01 | Pig Improvement Co Uk Ltd | Animales resistentes a la influenza a que tienen genes de anp32 editados. |
| US12471982B2 (en) | 2020-12-02 | 2025-11-18 | Cilag Gmbh International | Method for tissue treatment by surgical instrument |
| EP4281102A1 (en) | 2021-01-22 | 2023-11-29 | Mendus B.V. | Methods of tumor vaccination |
| CA3212351A1 (en) | 2021-03-12 | 2022-09-15 | Mendus B.V. | Methods of vaccination and use of cd47 blockade |
| WO2023064367A1 (en) | 2021-10-12 | 2023-04-20 | Selecta Biosciences, Inc. | Methods and compositions for attenuating anti-viral transfer vector igm responses |
| US12508021B2 (en) | 2021-11-01 | 2025-12-30 | Cilag Gmbh International | Devices, systems, and methods for detecting tissue and foreign objects during a surgical operation |
| US11957342B2 (en) | 2021-11-01 | 2024-04-16 | Cilag Gmbh International | Devices, systems, and methods for detecting tissue and foreign objects during a surgical operation |
| EP4430206A1 (en) | 2021-11-10 | 2024-09-18 | Encodia, Inc. | Methods for barcoding macromolecules in individual cells |
| WO2023105244A1 (en) | 2021-12-10 | 2023-06-15 | Pig Improvement Company Uk Limited | Editing tmprss2/4 for disease resistance in livestock |
| CA3241882A1 (en) | 2021-12-29 | 2023-07-06 | Bristol-Myers Squibb Company | Generation of landing pad cell lines |
| WO2023131616A1 (en) | 2022-01-05 | 2023-07-13 | Vib Vzw | Means and methods to increase abiotic stress tolerance in plants |
| WO2023131637A1 (en) | 2022-01-06 | 2023-07-13 | Vib Vzw | Improved silage grasses |
| WO2023144199A1 (en) | 2022-01-26 | 2023-08-03 | Vib Vzw | Plants having reduced levels of bitter taste metabolites |
| WO2023172624A1 (en) | 2022-03-09 | 2023-09-14 | Selecta Biosciences, Inc. | Immunosuppressants in combination with anti-igm agents and related dosing |
| WO2023220603A1 (en) | 2022-05-09 | 2023-11-16 | Regeneron Pharmaceuticals, Inc. | Vectors and methods for in vivo antibody production |
| WO2024013514A2 (en) | 2022-07-15 | 2024-01-18 | Pig Improvement Company Uk Limited | Gene edited livestock animals having coronavirus resistance |
| AU2023314808A1 (en) | 2022-07-29 | 2025-03-20 | Regeneron Pharmaceuticals, Inc. | Compositions and methods for transferrin receptor (tfr)-mediated delivery to the brain and muscle |
| CA3261296A1 (en) | 2022-08-05 | 2024-02-08 | Regeneron Pharmaceuticals, Inc. | TDP-43 VARIANTS RESISTANT TO AGGREGATION |
| WO2024107765A2 (en) | 2022-11-14 | 2024-05-23 | Regeneron Pharmaceuticals, Inc. | Compositions and methods for fibroblast growth factor receptor 3-mediated delivery to astrocytes |
| EP4658061A1 (en) | 2023-02-01 | 2025-12-10 | United Beet Seeds | Beet yellows virus resistance |
| WO2024163615A1 (en) | 2023-02-02 | 2024-08-08 | University Of Florida Research Foundation, Incorporated | Brain-derived neurotrophic factor-nano luciferase transgenic rodents and methods of use thereof |
| US12239091B2 (en) | 2023-03-27 | 2025-03-04 | Redsea Science And Technology Inc. | Tomato plant designated ‘MX20-06’ |
| CN116491599A (zh) * | 2023-06-26 | 2023-07-28 | 云南大台农台标农业科技有限公司 | 一种复合菌剂及其在猪饲料中的应用 |
| WO2025128981A1 (en) | 2023-12-14 | 2025-06-19 | Sohm, Inc. | Compositions and methods for genome editing |
| WO2025235388A1 (en) | 2024-05-06 | 2025-11-13 | Regeneron Pharmaceuticals, Inc. | Transgene genomic identification by nuclease-mediated long read sequencing |
Family Cites Families (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL8300698A (nl) | 1983-02-24 | 1984-09-17 | Univ Leiden | Werkwijze voor het inbouwen van vreemd dna in het genoom van tweezaadlobbige planten; agrobacterium tumefaciens bacterien en werkwijze voor het produceren daarvan; planten en plantecellen met gewijzigde genetische eigenschappen; werkwijze voor het bereiden van chemische en/of farmaceutische produkten. |
| EP0222493A1 (en) | 1985-10-04 | 1987-05-20 | Lubrizol Genetics Inc. | TR-based sub-TI plasmids |
| US5422251A (en) | 1986-11-26 | 1995-06-06 | Princeton University | Triple-stranded nucleic acids |
| US5176996A (en) | 1988-12-20 | 1993-01-05 | Baylor College Of Medicine | Method for making synthetic oligonucleotides which bind specifically to target sites on duplex DNA molecules, by forming a colinear triplex, the synthetic oligonucleotides and methods of use |
| US5550318A (en) * | 1990-04-17 | 1996-08-27 | Dekalb Genetics Corporation | Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof |
| US5436150A (en) | 1992-04-03 | 1995-07-25 | The Johns Hopkins University | Functional domains in flavobacterium okeanokoities (foki) restriction endonuclease |
| US5356802A (en) | 1992-04-03 | 1994-10-18 | The Johns Hopkins University | Functional domains in flavobacterium okeanokoites (FokI) restriction endonuclease |
| US5487994A (en) | 1992-04-03 | 1996-01-30 | The Johns Hopkins University | Insertion and deletion mutants of FokI restriction endonuclease |
| DE69334225D1 (de) | 1992-07-07 | 2008-07-31 | Japan Tobacco Inc | Verfahren zur transformation einer monokotyledon pflanze |
| US6242568B1 (en) | 1994-01-18 | 2001-06-05 | The Scripps Research Institute | Zinc finger protein derivatives and methods therefor |
| US6140466A (en) | 1994-01-18 | 2000-10-31 | The Scripps Research Institute | Zinc finger protein derivatives and methods therefor |
| CA2181548C (en) | 1994-01-18 | 2009-11-03 | Carlos F. Barbas, Iii | Zinc finger protein derivatives and methods therefor |
| US5585245A (en) | 1994-04-22 | 1996-12-17 | California Institute Of Technology | Ubiquitin-based split protein sensor |
| GB9824544D0 (en) | 1998-11-09 | 1999-01-06 | Medical Res Council | Screening system |
| DE69535829D1 (de) | 1994-08-20 | 2008-10-16 | Gendaq Ltd | Verbesserung in bezug auf bindungsproteine bei der erkennung von dna |
| US5789538A (en) | 1995-02-03 | 1998-08-04 | Massachusetts Institute Of Technology | Zinc finger proteins with high affinity new DNA binding specificities |
| US5773695A (en) | 1996-01-26 | 1998-06-30 | North Carolina State University | Plant nuclear scaffold attachment region and method for increasing gene expression in transgenic cells |
| US5925523A (en) | 1996-08-23 | 1999-07-20 | President & Fellows Of Harvard College | Intraction trap assay, reagents and uses thereof |
| GB2338237B (en) | 1997-02-18 | 2001-02-28 | Actinova Ltd | In vitro peptide or protein expression library |
| GB9703369D0 (en) | 1997-02-18 | 1997-04-09 | Lindqvist Bjorn H | Process |
| US6342345B1 (en) | 1997-04-02 | 2002-01-29 | The Board Of Trustees Of The Leland Stanford Junior University | Detection of molecular interactions by reporter subunit complementation |
| GB9710807D0 (en) | 1997-05-23 | 1997-07-23 | Medical Res Council | Nucleic acid binding proteins |
| GB9710809D0 (en) | 1997-05-23 | 1997-07-23 | Medical Res Council | Nucleic acid binding proteins |
| US6506559B1 (en) | 1997-12-23 | 2003-01-14 | Carnegie Institute Of Washington | Genetic inhibition by double-stranded RNA |
| AR014491A1 (es) | 1998-01-29 | 2001-02-28 | Dow Agrosciences Llc | Metodo para obtener plantas transgenicas fertiles de gossypium hirsutum. |
| US6410248B1 (en) | 1998-01-30 | 2002-06-25 | Massachusetts Institute Of Technology | General strategy for selecting high-affinity zinc finger proteins for diverse DNA target sites |
| ES2341926T3 (es) | 1998-03-02 | 2010-06-29 | Massachusetts Institute Of Technology | Poliproteinas con dedos de cinc que tienen enlazadores mejorados. |
| US6140081A (en) | 1998-10-16 | 2000-10-31 | The Scripps Research Institute | Zinc finger binding domains for GNN |
| US6453242B1 (en) | 1999-01-12 | 2002-09-17 | Sangamo Biosciences, Inc. | Selection of sites for targeting by zinc finger proteins and methods of designing zinc finger proteins to bind to preselected sites |
| US6534261B1 (en) * | 1999-01-12 | 2003-03-18 | Sangamo Biosciences, Inc. | Regulation of endogenous gene expression in cells using zinc finger proteins |
| US7013219B2 (en) | 1999-01-12 | 2006-03-14 | Sangamo Biosciences, Inc. | Regulation of endogenous gene expression in cells using zinc finger proteins |
| US6794136B1 (en) | 2000-11-20 | 2004-09-21 | Sangamo Biosciences, Inc. | Iterative optimization in the design of binding proteins |
| US20030104526A1 (en) * | 1999-03-24 | 2003-06-05 | Qiang Liu | Position dependent recognition of GNN nucleotide triplets by zinc fingers |
| US7030215B2 (en) | 1999-03-24 | 2006-04-18 | Sangamo Biosciences, Inc. | Position dependent recognition of GNN nucleotide triplets by zinc fingers |
| WO2001052620A2 (en) | 2000-01-21 | 2001-07-26 | The Scripps Research Institute | Methods and compositions to modulate expression in plants |
| CA2398155C (en) | 2000-01-24 | 2011-07-19 | Sangamo Biosciences, Inc. | Methods and compositions for linking binding domains in nucleic acid binding proteins |
| US20020061512A1 (en) | 2000-02-18 | 2002-05-23 | Kim Jin-Soo | Zinc finger domains and methods of identifying same |
| DE60126483T2 (de) | 2000-04-28 | 2007-12-06 | Sangamo BioSciences, Inc., Richmond | Gezielte Modifikation der Chromatinstruktur |
| AU2001263155A1 (en) | 2000-05-16 | 2001-11-26 | Massachusetts Institute Of Technology | Methods and compositions for interaction trap assays |
| JP2002060786A (ja) | 2000-08-23 | 2002-02-26 | Kao Corp | 硬質表面用殺菌防汚剤 |
| AU2002213431A1 (en) | 2000-09-29 | 2002-04-08 | Sangamo Biosciences, Inc. | Modulation of gene expression using localization domains |
| DK1353941T3 (da) * | 2001-01-22 | 2013-06-17 | Sangamo Biosciences Inc | Modificerede zinkfingerbindingsproteiner |
| GB0108491D0 (en) | 2001-04-04 | 2001-05-23 | Gendaq Ltd | Engineering zinc fingers |
| WO2003016496A2 (en) | 2001-08-20 | 2003-02-27 | The Scripps Research Institute | Zinc finger binding domains for cnn |
| ATE347593T1 (de) | 2002-01-23 | 2006-12-15 | Univ Utah Res Found | Zielgerichtete chromosomale mutagenese mit zinkfingernukleasen |
| EP1504092B2 (en) | 2002-03-21 | 2014-06-25 | Sangamo BioSciences, Inc. | Methods and compositions for using zinc finger endonucleases to enhance homologous recombination |
| WO2004037977A2 (en) | 2002-09-05 | 2004-05-06 | California Institute Of Thechnology | Use of chimeric nucleases to stimulate gene targeting |
| WO2005014794A2 (en) * | 2003-08-07 | 2005-02-17 | Duke University | Generation of low phytate plants by molecular disruption of inositol polyphosphate kinases |
| US7888121B2 (en) | 2003-08-08 | 2011-02-15 | Sangamo Biosciences, Inc. | Methods and compositions for targeted cleavage and recombination |
| ES2808687T3 (es) * | 2003-08-08 | 2021-03-01 | Sangamo Therapeutics Inc | Métodos y composiciones para escisión dirigida y recombinación |
| US8409861B2 (en) | 2003-08-08 | 2013-04-02 | Sangamo Biosciences, Inc. | Targeted deletion of cellular DNA sequences |
| CA2539439C (en) * | 2003-09-19 | 2012-10-23 | Sangamo Biosciences, Inc. | Engineered zinc finger proteins for regulation of gene expression |
| US7714187B2 (en) * | 2004-02-09 | 2010-05-11 | Pioneer Hi-Bred International, Inc. | Phytate polynucleotides and methods of use |
| JP4903689B2 (ja) | 2004-04-08 | 2012-03-28 | サンガモ バイオサイエンシズ インコーポレイテッド | 神経障害および神経変性症状を治療するための方法と組成物 |
| CN1984558B (zh) | 2004-04-30 | 2011-01-12 | 美国陶氏益农公司 | 新除草剂抗性基因 |
| AR050866A1 (es) | 2004-09-09 | 2006-11-29 | Dow Agrosciences Llc | Genes de inositol polifosfato 2-quinasa y usos de los mismos |
| EP1913149A4 (en) * | 2005-07-26 | 2009-08-05 | Sangamo Biosciences Inc | TARGETED INTEGRATION AND EXPRESSION OF EXOGENOUS NUCLEIC ACID SEQUENCES |
| CA2660485C (en) * | 2006-08-11 | 2016-04-12 | Sangamo Biosciences, Inc. | Zinc finger nuclease-mediated homologous recombination |
| US9187758B2 (en) * | 2006-12-14 | 2015-11-17 | Sangamo Biosciences, Inc. | Optimized non-canonical zinc finger proteins |
-
2007
- 2007-12-13 US US12/001,939 patent/US9187758B2/en active Active
- 2007-12-13 EP EP07853356.9A patent/EP2092068B1/en active Active
- 2007-12-13 DK DK11184934.5T patent/DK2415872T3/en active
- 2007-12-13 KR KR1020147036403A patent/KR101574529B1/ko not_active Expired - Fee Related
- 2007-12-13 JP JP2009541373A patent/JP5632610B2/ja not_active Expired - Fee Related
- 2007-12-13 MX MX2009006303A patent/MX2009006303A/es active IP Right Grant
- 2007-12-13 SI SI200731579T patent/SI2092068T1/sl unknown
- 2007-12-13 NZ NZ597995A patent/NZ597995A/xx not_active IP Right Cessation
- 2007-12-13 KR KR1020097012260A patent/KR101520507B1/ko not_active Expired - Fee Related
- 2007-12-13 WO PCT/US2007/025455 patent/WO2008076290A2/en not_active Ceased
- 2007-12-13 CN CN201310586968.2A patent/CN103613646B/zh not_active Expired - Fee Related
- 2007-12-13 EP EP16163183.3A patent/EP3070169B1/en not_active Not-in-force
- 2007-12-13 CA CA2669746A patent/CA2669746C/en active Active
- 2007-12-13 HU HUE11184934A patent/HUE029238T2/en unknown
- 2007-12-13 BR BRPI0720048A patent/BRPI0720048A8/pt not_active Application Discontinuation
- 2007-12-13 TW TW96147782A patent/TWI470079B/zh not_active IP Right Cessation
- 2007-12-13 SI SI200731809A patent/SI2415872T1/sl unknown
- 2007-12-13 PT PT111849345T patent/PT2415872T/pt unknown
- 2007-12-13 DK DK07853356.9T patent/DK2092068T3/en active
- 2007-12-13 ES ES11184934.5T patent/ES2586210T3/es active Active
- 2007-12-13 NZ NZ576800A patent/NZ576800A/xx not_active IP Right Cessation
- 2007-12-13 PT PT78533569T patent/PT2092068E/pt unknown
- 2007-12-13 DK DK11184941.0T patent/DK2412812T3/en active
- 2007-12-13 EP EP11184938.6A patent/EP2415873B1/en active Active
- 2007-12-13 EP EP11184934.5A patent/EP2415872B1/en active Active
- 2007-12-13 KR KR1020157033891A patent/KR101613624B1/ko not_active Expired - Fee Related
- 2007-12-13 PT PT11184938T patent/PT2415873E/pt unknown
- 2007-12-13 AU AU2007334468A patent/AU2007334468B2/en not_active Ceased
- 2007-12-13 KR KR1020167009592A patent/KR101723350B1/ko not_active Expired - Fee Related
- 2007-12-13 EP EP11184941.0A patent/EP2412812B1/en active Active
- 2007-12-13 CA CA2962856A patent/CA2962856A1/en not_active Abandoned
- 2007-12-13 PT PT111849410T patent/PT2412812E/pt unknown
- 2007-12-14 AR ARP070105643A patent/AR069896A1/es not_active Application Discontinuation
-
2008
- 2008-10-01 US US12/286,668 patent/US8921112B2/en active Active
-
2009
- 2009-05-07 CR CR10775A patent/CR10775A/es unknown
- 2009-05-26 EG EG2009050768A patent/EG26980A/xx active
- 2009-06-11 CO CO09061116A patent/CO6220864A2/es not_active Application Discontinuation
-
2015
- 2015-11-12 US US14/939,719 patent/US10662434B2/en active Active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CR10775A (es) | Proteinas de dedo de zin no canonicas optimizadas | |
| DK2046826T3 (da) | Exendin-fusionsproteiner | |
| FR2909857B1 (fr) | Endovalve. | |
| DE602006011613D1 (de) | Absaugsteuerung | |
| DE602006008264D1 (de) | Turbo-Auflader | |
| DK1849352T3 (da) | Mejetærsker | |
| EP2070658A4 (en) | CLAMP MACHINE | |
| FR2895920B1 (fr) | Pipette multivolumes. | |
| SE0702067L (sv) | Bestick | |
| DE502007000666D1 (de) | Endrohrblende | |
| EP2015785A4 (en) | AGRM2 ANTIGEN | |
| DE502005004418D1 (de) | Turbolader | |
| DE502007004910D1 (de) | Turbolader | |
| DE102006032477A8 (de) | Dunstabzugshaube | |
| DK2081952T3 (da) | Peptider | |
| BRPI0718609A2 (pt) | Anticorpos modificadores de doença cancerosa. | |
| ITCE20060002A1 (it) | Patok. | |
| FI20065208A0 (fi) | Peptidikonjugaatteja | |
| ITVT20060004A1 (it) | Rastrello arpionato | |
| FIU20060430U0 (fi) | Järjestelijä | |
| EE00628U1 (et) | Mäekombaini hambahoidja-tükimurdja | |
| ES1062681Y (es) | Grapadora | |
| TR200502727Y (tr) | Turbosarjör | |
| AT500662A3 (de) | Abgasturbolader | |
| FI20060992L (fi) | Sormiliitos |