CR20110029A - Moduladores de diamino-piridina, pirimidina, y piridazina del receptor h4 de histamina - Google Patents

Moduladores de diamino-piridina, pirimidina, y piridazina del receptor h4 de histamina

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Publication number
CR20110029A
CR20110029A CR20110029A CR20110029A CR20110029A CR 20110029 A CR20110029 A CR 20110029A CR 20110029 A CR20110029 A CR 20110029A CR 20110029 A CR20110029 A CR 20110029A CR 20110029 A CR20110029 A CR 20110029A
Authority
CR
Costa Rica
Prior art keywords
modulators
pyridazine
diamino
pyrimidine
pyridine
Prior art date
Application number
CR20110029A
Other languages
English (en)
Inventor
Hui Cai
Ronald L Wolin
Frank Chavez
Paul J Dunford
Andrew J Greenspan
Steven P Meduna
Jorge A Quiroz
Brad M Savall
Kevin L Tays
Jianmei Wei
Xiaohu Zhang
Robin L Thurmond
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41417123&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CR20110029(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of CR20110029A publication Critical patent/CR20110029A/es

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    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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  • Transplantation (AREA)
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Abstract

Compuestos que se pueden usar como moduladores del receptor H4, y en composiciones farmacéuticas y métodos para el tratamiento de estados de enfermedad, transtornos y afecciones.
CR20110029A 2008-06-12 2011-01-12 Moduladores de diamino-piridina, pirimidina, y piridazina del receptor h4 de histamina CR20110029A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6103908P 2008-06-12 2008-06-12
US11441608P 2008-11-13 2008-11-13
US11442508P 2008-11-13 2008-11-13

Publications (1)

Publication Number Publication Date
CR20110029A true CR20110029A (es) 2011-07-06

Family

ID=41417123

Family Applications (1)

Application Number Title Priority Date Filing Date
CR20110029A CR20110029A (es) 2008-06-12 2011-01-12 Moduladores de diamino-piridina, pirimidina, y piridazina del receptor h4 de histamina

Country Status (20)

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US (3) US8841287B2 (es)
EP (1) EP2315521B1 (es)
JP (1) JP5658662B2 (es)
KR (1) KR101600278B1 (es)
CN (1) CN102118969B (es)
AU (1) AU2009257434B2 (es)
BR (1) BRPI0915720A2 (es)
CA (1) CA2727684C (es)
CO (1) CO6321192A2 (es)
CR (1) CR20110029A (es)
EA (1) EA018198B1 (es)
EC (1) ECSP10010675A (es)
IL (1) IL209593A (es)
MX (1) MX2010013726A (es)
MY (1) MY158927A (es)
NI (1) NI201000214A (es)
NZ (1) NZ589532A (es)
PE (1) PE20110061A1 (es)
WO (1) WO2009152325A1 (es)
ZA (1) ZA201100298B (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101460483B (zh) 2006-03-31 2013-05-08 詹森药业有限公司 作为组胺h4受体调节剂的苯并咪唑-2-基嘧啶和吡嗪
EA019143B1 (ru) * 2008-06-12 2014-01-30 Янссен Фармацевтика Нв Использование антагонистов н4-гистаминовых рецепторов для лечения послеоперационных спаек
CN102118969B (zh) 2008-06-12 2017-03-08 詹森药业有限公司 组胺h4受体的二氨基吡啶、二氨基嘧啶和二氨基哒嗪调节剂
US9371311B2 (en) 2008-06-30 2016-06-21 Janssen Pharmaceutica Nv Benzoimidazol-2-yl pyrimidine derivatives
NZ596123A (en) * 2009-05-19 2014-08-29 Dow Agrosciences Llc Compounds and methods for controlling fungi
WO2011078143A1 (ja) * 2009-12-22 2011-06-30 塩野義製薬株式会社 ピリミジン誘導体およびそれらを含有する医薬組成物
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