JO3516B1 - مُعدِّلات بنزإيميدازول-2-يل بيريميدين لمستقبل الهستامين h4 - Google Patents

مُعدِّلات بنزإيميدازول-2-يل بيريميدين لمستقبل الهستامين h4

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Publication number
JO3516B1
JO3516B1 JOP/2014/0074A JOP20140074A JO3516B1 JO 3516 B1 JO3516 B1 JO 3516B1 JO P20140074 A JOP20140074 A JO P20140074A JO 3516 B1 JO3516 B1 JO 3516B1
Authority
JO
Jordan
Prior art keywords
benzimidazole
histamine
ylpyrimidine
modulators
receptor
Prior art date
Application number
JOP/2014/0074A
Other languages
English (en)
Inventor
B Hickey Magali
Conza Matteo
Lochner Susanne
Horns Stefan
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of JO3516B1 publication Critical patent/JO3516B1/ar

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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Abstract

يتعلق هذا الاختراع ببنزإيميدازول-2-يل بيريميدينات وطرق تنقيتها وتركيبات صيدلانية وطرق للحصول لمعالجة حالات مرضية واضطرابات وحالات تحدث نتيجة لنشاط مستقبل الهستامين H4، بما في ذلك الحساسية والربو وأمراض المناعة الذاتية والحكة
JOP/2014/0074A 2013-03-06 2014-03-06 مُعدِّلات بنزإيميدازول-2-يل بيريميدين لمستقبل الهستامين h4 JO3516B1 (ar)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361773706P 2013-03-06 2013-03-06
US201361776260P 2013-03-11 2013-03-11
US201361784909P 2013-03-14 2013-03-14

Publications (1)

Publication Number Publication Date
JO3516B1 true JO3516B1 (ar) 2020-07-05

Family

ID=51488591

Family Applications (1)

Application Number Title Priority Date Filing Date
JOP/2014/0074A JO3516B1 (ar) 2013-03-06 2014-03-06 مُعدِّلات بنزإيميدازول-2-يل بيريميدين لمستقبل الهستامين h4

Country Status (38)

Country Link
US (4) US8859575B2 (ar)
EP (2) EP2964229B1 (ar)
JP (1) JP6471103B2 (ar)
KR (1) KR102230383B1 (ar)
CN (1) CN105025898B (ar)
AU (1) AU2014225675B2 (ar)
BR (1) BR112015021463A8 (ar)
CA (1) CA2903737C (ar)
CL (1) CL2015002434A1 (ar)
CR (1) CR20150435A (ar)
CY (1) CY1122545T1 (ar)
DK (1) DK2964229T3 (ar)
DO (1) DOP2016000027A (ar)
EA (1) EA201591648A1 (ar)
ES (1) ES2773543T3 (ar)
GT (1) GT201500243A (ar)
HR (1) HRP20200253T1 (ar)
HU (1) HUE047681T2 (ar)
IL (1) IL240247B (ar)
JO (1) JO3516B1 (ar)
LT (1) LT2964229T (ar)
MX (1) MX373874B (ar)
MY (1) MY180726A (ar)
NZ (1) NZ710640A (ar)
PE (1) PE20151536A1 (ar)
PH (1) PH12015501731A1 (ar)
PL (1) PL2964229T3 (ar)
PT (1) PT2964229T (ar)
RS (1) RS59909B1 (ar)
SA (1) SA515360981B1 (ar)
SG (1) SG11201507117XA (ar)
SI (1) SI2964229T1 (ar)
SM (1) SMT202000084T1 (ar)
TW (1) TWI617554B (ar)
UA (1) UA118754C2 (ar)
UY (1) UY35370A (ar)
WO (1) WO2014138368A1 (ar)
ZA (1) ZA201507351B (ar)

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US9371311B2 (en) 2008-06-30 2016-06-21 Janssen Pharmaceutica Nv Benzoimidazol-2-yl pyrimidine derivatives
SMT202000084T1 (it) 2013-03-06 2020-03-13 Janssen Pharmaceutica Nv Modulatori benzoimidazol-2-il pirimidinici del recettore h4 dell'istamina
JO3509B1 (ar) 2013-03-14 2020-07-05 Janssen Pharmaceutica Nv معدلات p2x7
US9040534B2 (en) 2013-03-14 2015-05-26 Janssen Pharmaceutica Nv [1,2,4]triazolo[4,3-a]pyrazines as P2X7 modulators
TWI644671B (zh) 2013-03-14 2018-12-21 比利時商健生藥品公司 Ｐ２ｘ７調節劑
US9604982B2 (en) 2013-03-14 2017-03-28 Janssen Pharmaceutica Nv P2X7 modulators
WO2016039977A1 (en) 2014-09-12 2016-03-17 Janssen Pharmaceutica Nv P2x7 modulators
AU2015315693B2 (en) 2014-09-12 2020-01-16 Janssen Pharmaceutica Nv P2X7 modulating n-acyl-triazolopyrazines
US20180325931A1 (en) 2017-01-21 2018-11-15 Ningbo Zhiming Biotechnology Co., Ltd. Use of paeoniflorin-6'-o-benzenesulfonate in treatment of sjögren's syndrome
KR20210069079A (ko) 2018-09-28 2021-06-10 얀센 파마슈티카 엔.브이. 모노아실글리세롤 리파아제 조절제
MY205440A (en) 2018-09-28 2024-10-21 Janssen Pharmaceutica Nv Monoacylglycerol lipase modulators
JP7697934B2 (ja) 2019-09-30 2025-06-24 ヤンセン ファーマシューティカ エヌ．ベー． 放射線標識されたｍｇｌ ｐｅｔリガンド
BR112022019077A2 (pt) 2020-03-26 2022-12-27 Janssen Pharmaceutica Nv Moduladores da monoacilglicerol lipase

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