JO3516B1 - مُعدِّلات بنزإيميدازول-2-يل بيريميدين لمستقبل الهستامين h4 - Google Patents

مُعدِّلات بنزإيميدازول-2-يل بيريميدين لمستقبل الهستامين h4

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Publication number
JO3516B1
JO3516B1 JOP/2014/0074A JOP20140074A JO3516B1 JO 3516 B1 JO3516 B1 JO 3516B1 JO P20140074 A JOP20140074 A JO P20140074A JO 3516 B1 JO3516 B1 JO 3516B1
Authority
JO
Jordan
Prior art keywords
benzimidazole
histamine
ylpyrimidine
modulators
receptor
Prior art date
Application number
JOP/2014/0074A
Other languages
English (en)
Inventor
B Hickey Magali
Conza Matteo
Lochner Susanne
Horns Stefan
Original Assignee
Janssen Pharmaceutica Nv
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Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of JO3516B1 publication Critical patent/JO3516B1/ar

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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Abstract

يتعلق هذا الاختراع ببنزإيميدازول-2-يل بيريميدينات وطرق تنقيتها وتركيبات صيدلانية وطرق للحصول لمعالجة حالات مرضية واضطرابات وحالات تحدث نتيجة لنشاط مستقبل الهستامين H4، بما في ذلك الحساسية والربو وأمراض المناعة الذاتية والحكة
JOP/2014/0074A 2013-03-06 2014-03-06 مُعدِّلات بنزإيميدازول-2-يل بيريميدين لمستقبل الهستامين h4 JO3516B1 (ar)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361773706P 2013-03-06 2013-03-06
US201361776260P 2013-03-11 2013-03-11
US201361784909P 2013-03-14 2013-03-14

Publications (1)

Publication Number Publication Date
JO3516B1 true JO3516B1 (ar) 2020-07-05

Family

ID=51488591

Family Applications (1)

Application Number Title Priority Date Filing Date
JOP/2014/0074A JO3516B1 (ar) 2013-03-06 2014-03-06 مُعدِّلات بنزإيميدازول-2-يل بيريميدين لمستقبل الهستامين h4

Country Status (38)

Country Link
US (4) US8859575B2 (ar)
EP (2) EP2964229B1 (ar)
JP (1) JP6471103B2 (ar)
KR (1) KR102230383B1 (ar)
CN (1) CN105025898B (ar)
AU (1) AU2014225675B2 (ar)
BR (1) BR112015021463A8 (ar)
CA (1) CA2903737C (ar)
CL (1) CL2015002434A1 (ar)
CR (1) CR20150435A (ar)
CY (1) CY1122545T1 (ar)
DK (1) DK2964229T3 (ar)
DO (1) DOP2016000027A (ar)
EA (1) EA201591648A1 (ar)
ES (1) ES2773543T3 (ar)
GT (1) GT201500243A (ar)
HR (1) HRP20200253T1 (ar)
HU (1) HUE047681T2 (ar)
IL (1) IL240247B (ar)
JO (1) JO3516B1 (ar)
LT (1) LT2964229T (ar)
MX (1) MX373874B (ar)
MY (1) MY180726A (ar)
NZ (1) NZ710640A (ar)
PE (1) PE20151536A1 (ar)
PH (1) PH12015501731A1 (ar)
PL (1) PL2964229T3 (ar)
PT (1) PT2964229T (ar)
RS (1) RS59909B1 (ar)
SA (1) SA515360981B1 (ar)
SG (1) SG11201507117XA (ar)
SI (1) SI2964229T1 (ar)
SM (1) SMT202000084T1 (ar)
TW (1) TWI617554B (ar)
UA (1) UA118754C2 (ar)
UY (1) UY35370A (ar)
WO (1) WO2014138368A1 (ar)
ZA (1) ZA201507351B (ar)

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ATE478067T1 (de) 2006-03-31 2010-09-15 Janssen Pharmaceutica Nv Benzoimidazol-2-yl pyridine und pyrazine als modulatoren des histamin-h4-rezeptors
US9371311B2 (en) 2008-06-30 2016-06-21 Janssen Pharmaceutica Nv Benzoimidazol-2-yl pyrimidine derivatives
JO3516B1 (ar) 2013-03-06 2020-07-05 Janssen Pharmaceutica Nv مُعدِّلات بنزإيميدازول-2-يل بيريميدين لمستقبل الهستامين h4
JP6294953B2 (ja) 2013-03-14 2018-03-14 ヤンセン ファーマシューティカ エヌ．ベー． Ｐ２ｘ７調節物質
TWI599567B (zh) 2013-03-14 2017-09-21 健生藥品公司 Ｐ２ｘ７調節劑
ES2689526T3 (es) 2013-03-14 2018-11-14 Janssen Pharmaceutica Nv Moduladores de P2X7
JO3509B1 (ar) 2013-03-14 2020-07-05 Janssen Pharmaceutica Nv معدلات p2x7
WO2016039977A1 (en) 2014-09-12 2016-03-17 Janssen Pharmaceutica Nv P2x7 modulators
AU2015315693B2 (en) 2014-09-12 2020-01-16 Janssen Pharmaceutica Nv P2X7 modulating n-acyl-triazolopyrazines
WO2018133139A1 (zh) 2017-01-21 2018-07-26 宁波知明生物科技有限公司 芍药苷-6'-o-苯磺酸酯在治疗干燥综合征的应用
JP7413368B2 (ja) 2018-09-28 2024-01-15 ヤンセン ファーマシューティカ エヌ．ベー． モノアシルグリセロールリパーゼ調節因子
MA53721A (fr) 2018-09-28 2021-09-15 Janssen Pharmaceutica Nv Modulateurs de la monoacylglycérol lipase
CA3156100A1 (en) 2019-09-30 2021-04-08 Janssen Pharmaceutica Nv Radiolabelled mgl pet ligands
CA3176946A1 (en) 2020-03-26 2021-09-30 Janssen Pharmaceutica Nv Monoacylglycerol lipase modulators

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