CR20120391A - Sistema y método para la filtración de partículas - Google Patents

Sistema y método para la filtración de partículas

Info

Publication number
CR20120391A
CR20120391A CR20120391A CR20120391A CR20120391A CR 20120391 A CR20120391 A CR 20120391A CR 20120391 A CR20120391 A CR 20120391A CR 20120391 A CR20120391 A CR 20120391A CR 20120391 A CR20120391 A CR 20120391A
Authority
CR
Costa Rica
Prior art keywords
filtration
particles
particle
modalities
methods
Prior art date
Application number
CR20120391A
Other languages
English (en)
Inventor
Lotien Huang
Original Assignee
Cytovera Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cytovera Inc filed Critical Cytovera Inc
Publication of CR20120391A publication Critical patent/CR20120391A/es

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D29/00—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor
    • B01D29/50—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor with multiple filtering elements, characterised by their mutual disposition
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D29/00—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor
    • B01D29/01—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor with flat filtering elements
    • B01D29/03—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor with flat filtering elements self-supporting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5021—Test tubes specially adapted for centrifugation purposes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5025—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures for parallel transport of multiple samples
    • B01L3/50255—Multi-well filtration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
    • B81B1/00—Devices without movable or flexible elements, e.g. microcapillary devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/041—Connecting closures to device or container
    • B01L2300/042—Caps; Plugs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0829—Multi-well plates; Microtitration plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B01L2400/049—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics vacuum
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y80/00—Products made by additive manufacturing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/04—Cell isolation or sorting
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1028—Sorting particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1029—Particle size

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Computer Hardware Design (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Separation Of Solids By Using Liquids Or Pneumatic Power (AREA)
  • Filtering Materials (AREA)
  • Wood Science & Technology (AREA)
  • External Artificial Organs (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Sustainable Development (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

Modalidades de la presente descripción presentan un sistema de filtración que comprende un módulo de filtración para la filtración de partículas y métodos para usar el dispositivo para el aislamiento de partículas.
CR20120391A 2009-12-23 2012-07-23 Sistema y método para la filtración de partículas CR20120391A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28973009P 2009-12-23 2009-12-23
US29461110P 2010-01-13 2010-01-13

Publications (1)

Publication Number Publication Date
CR20120391A true CR20120391A (es) 2012-11-21

Family

ID=44196143

Family Applications (1)

Application Number Title Priority Date Filing Date
CR20120391A CR20120391A (es) 2009-12-23 2012-07-23 Sistema y método para la filtración de partículas

Country Status (16)

Country Link
US (2) US8679751B2 (es)
EP (1) EP2516320A4 (es)
JP (2) JP5624629B2 (es)
KR (1) KR101443133B1 (es)
CN (1) CN102791616B (es)
AU (1) AU2010336424B2 (es)
BR (1) BR112012018376A2 (es)
CA (1) CA2785390C (es)
CR (1) CR20120391A (es)
DO (1) DOP2012000181A (es)
IL (1) IL220274A (es)
MX (1) MX344460B (es)
RU (1) RU2539989C2 (es)
SG (1) SG181676A1 (es)
TW (1) TWI566793B (es)
WO (1) WO2011079217A1 (es)

Families Citing this family (135)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10632237B2 (en) 2006-10-09 2020-04-28 Minnetronix, Inc. Tangential flow filter system for the filtration of materials from biologic fluids
US10850235B2 (en) 2006-10-09 2020-12-01 Minnetronix, Inc. Method for filtering cerebrospinal fluid (CSF) including monitoring CSF flow
ES2845146T3 (es) 2006-10-09 2021-07-26 Neurofluidics Inc Sistema de purificación de líquido cefalorraquídeo
AU2010336424B2 (en) 2009-12-23 2013-06-13 Cytovera, Inc. A system and method for particle filtration
ITTO20100068U1 (it) * 2010-04-20 2011-10-21 Eltek Spa Dispositivi microfluidici e/o attrezzature per dispositivi microfluidici
ES2725564T3 (es) 2011-11-08 2019-09-24 Auxocell Laboratories Inc Sistemas y métodos de procesamiento celular
MX353212B (es) 2011-12-07 2018-01-08 Cytovera Inc Metodo y dispositivo para el procesamiento de muestras.
JP5963159B2 (ja) * 2012-01-05 2016-08-03 日立化成株式会社 細胞捕捉デバイス
DE102012103256A1 (de) * 2012-04-16 2013-10-17 Karlsruher Institut für Technologie Mikrostrukturapparat mit optischer Oberflächengüte sowie Verfahren zur Herstellung desselben
DE102013209718B4 (de) 2012-06-22 2015-09-10 Human Med Ag Vorrichtung zum Separieren von adulten Stammzellen
KR101303059B1 (ko) * 2012-06-28 2013-09-03 포항공과대학교 산학협력단 물과 기름을 선택적으로 분리할 수 있는 극친수성 여과 구조물
DE102012220250A1 (de) * 2012-11-07 2014-05-08 Hahn-Schickard-Gesellschaft für angewandte Forschung e.V. Fluidikmodul für eine zentrifugale filtration und verfahren zum filtern einer probe
US9386948B2 (en) 2012-12-05 2016-07-12 Theranos, Inc. Systems, devices, and methods for bodily fluid sample transport
US10248765B1 (en) 2012-12-05 2019-04-02 Theranos Ip Company, Llc Systems, devices, and methods for bodily fluid sample collection, transport, and handling
US9862987B2 (en) 2013-01-16 2018-01-09 The Regents Of The University Of California Label free molecular detection methods, systems and devices
WO2014113598A2 (en) * 2013-01-16 2014-07-24 The Regents Of The University Of California Microfluidic devices to extract, concentrate and isolate molecules
JP6116709B2 (ja) * 2013-02-05 2017-04-19 ポカード・ディアグノスティクス・リミテッドＰｏｃａｒｅｄ Ｄｉａｇｎｏｓｔｉｃｓ， Ｌｔｄ． フィルタ装置及びその使用方法
BR112015022738B1 (pt) 2013-03-15 2022-11-29 Labrador Diagnostics Llc Dispositivo para utilização com um componente de amostra líquida formado
US20150273467A1 (en) * 2013-03-15 2015-10-01 Theranos, Inc. Methods and devices for sample collection and sample separation
EP2971287B1 (en) 2013-03-15 2019-08-14 GPB Scientific, LLC On-chip microfluidic processing of particles
US20140342375A1 (en) * 2013-03-15 2014-11-20 University Of Maryland Microfluidic processing of leukocytes for molecular diagnostic testing
US12590955B2 (en) 2013-03-15 2026-03-31 Zeon Corporation Methods and systems for processing particles
US20150064153A1 (en) 2013-03-15 2015-03-05 The Trustees Of Princeton University High efficiency microfluidic purification of stem cells to improve transplants
EP3608022A1 (en) 2013-03-15 2020-02-12 The Trustees of Princeton University Methods and devices for high throughput purification
CN103190245B (zh) * 2013-04-01 2015-01-07 中国水产科学研究院黑龙江水产研究所 冰下着生藻类的采集装置及其方法
SG10201801188XA (en) 2013-08-16 2018-03-28 Massachusetts Inst Technology Selective delivery of material to cells
WO2015044435A1 (en) * 2013-09-30 2015-04-02 Westfaelische Wilhelms-Universitaet Muenster Method of enriching or isolating a target cell population
NO342032B1 (no) * 2013-10-25 2018-03-12 Trilobite Innovation As Fluidraffineringsanordning og -sammenstilling
GB201319139D0 (en) * 2013-10-30 2013-12-11 Exmoor Pharma Concepts Ltd Apparatus and method for filtration of a suspension
CN113640170B (zh) * 2013-12-04 2022-11-18 普凯尔德诊断技术有限公司 用于处理和分析通过切向过滤提取的颗粒的方法和装置
US20150166956A1 (en) 2013-12-16 2015-06-18 General Electric Company Devices for separation of particulates, associated methods and systems
CA2937486A1 (en) * 2014-01-20 2015-07-23 Halcyon Biomedical, Incorporated Passive separation of whole blood
US10518196B2 (en) 2014-01-29 2019-12-31 General Electric Company Devices for separation of particulates, associated methods and systems
CN106413904A (zh) * 2014-01-31 2017-02-15 帝斯曼知识产权资产管理有限公司 脂肪组织离心装置和使用方法
MX2016011474A (es) * 2014-03-05 2016-11-16 Theranos Inc Metodos y dispositivos para recoleccion de muestras y separacion de muestras.
US9782707B2 (en) 2014-03-24 2017-10-10 Fenwal, Inc. Biological fluid filters having flexible walls and methods for making such filters
US10376627B2 (en) 2014-03-24 2019-08-13 Fenwal, Inc. Flexible biological fluid filters
US9968738B2 (en) 2014-03-24 2018-05-15 Fenwal, Inc. Biological fluid filters with molded frame and methods for making such filters
US10159778B2 (en) 2014-03-24 2018-12-25 Fenwal, Inc. Biological fluid filters having flexible walls and methods for making such filters
US9796166B2 (en) 2014-03-24 2017-10-24 Fenwal, Inc. Flexible biological fluid filters
EP3154694B1 (en) 2014-06-13 2025-01-29 Children's Medical Center Corporation Products and methods to isolate mitochondria
USD748462S1 (en) 2014-08-11 2016-02-02 Auxocell Laboratories, Inc. Centrifuge clip
US9993748B2 (en) 2014-08-11 2018-06-12 Auxocell Laboratories, Inc. Centrifuge clip and method
JP6509330B2 (ja) * 2014-09-05 2019-05-08 イマジン ティーエフ，エルエルシー 微細構造分離フィルタ
US10124275B2 (en) * 2014-09-05 2018-11-13 Imagine Tf, Llc Microstructure separation filters
EP3209766A4 (en) 2014-10-20 2018-08-15 University of Utah Research Foundation Tissue sample processing system and associated methods
RU2739794C2 (ru) 2014-10-31 2020-12-28 Массачусетс Инститьют Оф Текнолоджи Доставка биомолекул в клетки иммунной системы
EP3215270B1 (en) 2014-11-03 2020-05-27 The General Hospital Corporation Concentrating particles in a microfluidic device
WO2016080609A1 (ko) 2014-11-20 2016-05-26 울산과학기술원 입자 여과 장치 및 입자 여과 방법
KR101776245B1 (ko) 2014-11-20 2017-09-11 울산과학기술원 입자 여과 장치 및 입자 여과 방법
JP6382699B2 (ja) * 2014-11-28 2018-08-29 株式会社東芝 マイクロ分析チップ
AU2016206870B2 (en) 2015-01-12 2022-02-17 Massachusetts Institute Of Technology Gene editing through microfluidic delivery
GB2534182A (en) 2015-01-15 2016-07-20 Univ Dublin City Microfluidic device
CN104549588B (zh) * 2015-01-20 2016-04-06 重庆科技学院 一种多级微球筛选芯片及使用方法
US10702647B2 (en) * 2015-03-10 2020-07-07 Viatar LLC Systems, methods, and devices for removing circulating tumor cells from blood
US9868659B2 (en) 2015-04-17 2018-01-16 General Electric Company Subsurface water purification method
EP3302764A1 (en) 2015-06-08 2018-04-11 Becton, Dickinson and Company Filtration cell and method for filtering a biological sample
US20160367918A1 (en) * 2015-06-22 2016-12-22 Fuji Electric Co., Ltd. Filter system
US11147540B2 (en) 2015-07-01 2021-10-19 Minnetronix, Inc. Introducer sheath and puncture tool for the introduction and placement of a catheter in tissue
AU2016289530B2 (en) 2015-07-09 2021-05-06 Massachusetts Institute Of Technology Delivery of materials to anucleate cells
US10371606B2 (en) 2015-07-21 2019-08-06 Theraos IP Company, LLC Bodily fluid sample collection and transport
WO2017023419A1 (en) 2015-08-05 2017-02-09 Minnetronix, Inc. Tangential flow filter system for the filtration of materials from biologic fluids
US10976232B2 (en) 2015-08-24 2021-04-13 Gpb Scientific, Inc. Methods and devices for multi-step cell purification and concentration
WO2017041051A1 (en) 2015-09-04 2017-03-09 Sqz Biotechnologies Company Intracellular delivery of biomolecules to cells comprising a cell wall
WO2017044888A1 (en) 2015-09-09 2017-03-16 Theranos, Inc. Methods and devices for sample collection and sample separation
CN105203375B (zh) * 2015-09-16 2018-05-22 北京大学 一种高通量的血浆分离器件及其制备方法
KR101891890B1 (ko) * 2015-10-23 2018-08-28 울산과학기술원 원심력 기반 나노 입자 분리장치 및 이를 이용한 나노 입자 분리방법
WO2017077385A1 (en) * 2015-11-05 2017-05-11 Abi Micro Filters Multi-layered water purifying device for the protection of the washing machine and dish washer
CA3006975C (en) 2015-12-04 2022-02-22 Minnetronix, Inc. Systems and methods for the conditioning of cerebrospinal fluid
KR101791671B1 (ko) 2015-12-31 2017-11-20 주식회사 큐리오시스 미세입자 분리 및 정렬 장치, 및 그 방법
ES3057779T3 (en) 2016-01-15 2026-03-04 Childrens Medical Ct Corp Therapeutic use of mitochondria and combined mitochondrial agents
US10493409B2 (en) * 2016-03-02 2019-12-03 Becton, Dickinson And Company Biological fluid separation device
US11325948B2 (en) 2016-03-19 2022-05-10 Exuma Biotech Corp. Methods and compositions for genetically modifying lymphocytes to express polypeptides comprising the intracellular domain of MPL
US12590321B2 (en) 2016-03-19 2026-03-31 Exuma Biotech Corp. Methods and compositions for genetically modifying and expanding lymphocytes and regulating the activity thereof
US11111505B2 (en) 2016-03-19 2021-09-07 Exuma Biotech, Corp. Methods and compositions for transducing lymphocytes and regulating the activity thereof
WO2017182776A1 (en) * 2016-04-18 2017-10-26 Momentum Bioscience Limited Filter arrangement
CN109070077B (zh) 2016-04-28 2022-04-01 惠普发展公司，有限责任合伙企业 微流体过滤
RU2770492C2 (ru) 2016-05-03 2022-04-18 ЭсКьюЗед БАЙОТЕКНОЛОДЖИЗ КОМПАНИ Внутриклеточная доставка биологических молекул для индуцирования толерантности
RU2747878C2 (ru) * 2016-05-03 2021-05-17 ЭсКьюЗед БАЙОТЕКНОЛОДЖИЗ КОМПАНИ Внутриклеточная доставка биомолекул для индукции толерантности
JP6933212B2 (ja) * 2016-06-20 2021-09-08 凸版印刷株式会社 液体媒体の置換方法及び該方法のための流路デバイス
KR101711792B1 (ko) * 2016-06-27 2017-03-06 한국기계연구원 고속처리 미세유체소자
JPWO2018003476A1 (ja) * 2016-06-30 2019-01-17 富士フイルム株式会社 細胞懸濁液の膜分離方法及び細胞培養装置
US11097270B2 (en) 2016-07-15 2021-08-24 Hewlett-Packard Development Company, L.P. Microfluidic filtering system
CN113663749B (zh) * 2016-07-21 2023-06-20 新加坡科技研究局 用于高体积分数颗粒微滤的外壁聚焦的设备及其制造方法
CN107884562B (zh) 2016-09-30 2020-10-16 爱科来株式会社 粒子的磁标记方法和标记装置
WO2018073767A1 (en) * 2016-10-18 2018-04-26 Menarini Silicon Biosystems S.P.A. Microfluidic device, microfluidic system and method for the isolation of particles
IT201600104645A1 (it) * 2016-10-18 2018-04-18 Menarini Silicon Biosystems Spa Dispositivo microfluidico e metodo per l'isolamento di particelle
IT201600104612A1 (it) * 2016-10-18 2018-04-18 Menarini Silicon Biosystems Spa Sistema microfluidico e metodo per l'isolamento di particelle
US10471425B2 (en) * 2017-02-16 2019-11-12 International Business Machines Corporation Automated machine for sorting of biological fluids
US11857966B1 (en) 2017-03-15 2024-01-02 Labrador Diagnostics Llc Methods and devices for sample collection and sample separation
WO2018183744A1 (en) 2017-03-29 2018-10-04 The Research Foundation For The State University Of New York Microfluidic device and methods
WO2019005833A1 (en) 2017-06-26 2019-01-03 Mendoza Estevan SAMPLE FILTERING DEVICE
TWI671397B (zh) * 2017-07-14 2019-09-11 國立中興大學 粒線體萃取裝置
CN107523481B (zh) * 2017-08-17 2020-11-13 北京旌准医疗科技有限公司 一种基于微流控芯片的微纳生物粒子分选设备
EP3675876A4 (en) 2017-09-01 2021-06-02 GPB Scientific, Inc. METHOD FOR PRODUCING THERAPEUTICALLY ACTIVE CELLS USING MICROFLUIDICS
WO2019084410A1 (en) * 2017-10-26 2019-05-02 Repligen Corporation MICRO-ALTERNATIVE TANGENTIALLY FLOWING INFUSION FILTER, TREATMENT CONTAINER, AND METHODS OF USING THE SAME
US11524293B2 (en) * 2018-01-17 2022-12-13 Sartorius Stedim North America Inc. Cell separation device, method and system
KR102056938B1 (ko) * 2018-01-26 2019-12-17 (주)메타포어 매트릭스 구조를 가진 멤브레인 구조체 및 이를 이용한 생체분자 필터
EP3752828A4 (en) * 2018-02-16 2021-11-24 Astrego Diagnostics AB MICROFLUIDIC DEVICE
MA52003A (fr) 2018-03-12 2021-01-20 Sqz Biotechnologies Co Procédés de traitement de maladies associées au hpv
CN108949522B (zh) * 2018-07-19 2022-02-08 重庆医科大学附属第三医院(捷尔医院） 整形美容用自体脂肪活性细胞过滤装置
DE102018212930B3 (de) * 2018-08-02 2019-11-07 Hahn-Schickard-Gesellschaft für angewandte Forschung e.V. Vorrichtung und Verfahren zum Leiten einer Flüssigkeit durch ein poröses Medium
EP3837035B1 (en) 2018-08-16 2026-05-20 Emd Millipore Corp Closed bioprocessing device
ES2983667T3 (es) * 2019-01-25 2024-10-24 Becton Dickinson Co Métodos y aparatos para extraer de manera selectiva los constituyentes de muestras biológicas
JP7610773B2 (ja) 2019-02-28 2025-01-09 ステムセル テクノロジーズ カナダ インコーポレーテッド 免疫応答を改変するためのｐｂｍｃへの生体分子の送達
EP3938084A1 (en) * 2019-03-11 2022-01-19 Genzyme Corporation Tangential viral filtration
KR20210149791A (ko) 2019-04-08 2021-12-09 에스큐지 바이오테크놀로지스 컴퍼니 페이로드를 세포 내로 전달하기 위한 시스템에서 이용하기 위한 카트리지
GB2580723A (en) * 2019-05-02 2020-07-29 Renishaw Plc Powder handling apparatus
US20220298489A1 (en) * 2019-06-17 2022-09-22 Georgia Tech Research Corporation Filtration-based systems and methods for isolation of clustered particles
CN110160942B (zh) * 2019-07-01 2022-03-29 重庆交通大学 一种河流水域鱼卵监测装置
JP7384207B2 (ja) * 2019-09-09 2023-11-21 株式会社村田製作所 濃縮装置及び濃縮方法
CN110608989B (zh) * 2019-10-11 2021-12-21 西安石油大学 一种纳米尺度聚合物微球在中高渗油藏适用性的筛选方法
KR20210053010A (ko) * 2019-11-01 2021-05-11 주식회사라이브셀인스트루먼트 세포 분주 및 배양용 디스크, 실시간 모니터링 시스템 및 세포 분주 및 배양 방법
US20230111159A1 (en) * 2020-03-05 2023-04-13 Exuma Biotech Corp Methods and compositions for the delivery of modified lymphocyte aggregates
CN112304827B (zh) * 2020-04-07 2024-02-02 中国石油天然气股份有限公司 油田产出液中聚合物微球含量获取方法及装置
WO2022079494A2 (en) * 2020-10-15 2022-04-21 Sartorius Stedim Biotech Gmbh Channel designs and components
JP7682619B2 (ja) * 2020-10-19 2025-05-26 キヤノンメディカルシステムズ株式会社 誘導多能性幹細胞樹立装置及び方法
RU2757639C1 (ru) * 2021-02-12 2021-10-19 Общество с ограниченной ответственностью «ЭНЕРДЖИН» Способ выделения опухолевых клеток из периферической крови
US20220313962A1 (en) * 2021-04-01 2022-10-06 Xcath, Inc. Guidewire controller cassette and using method thereof
DE102021204675B4 (de) * 2021-05-07 2023-05-17 Lpkf Laser & Electronics Se Vorrichtung und Verfahren zur Zellkultivierung
CN117460670A (zh) * 2021-06-07 2024-01-26 普莱克斯姆公司 具有珠大小排除的用于测定装置的转移分配器
US20240269678A1 (en) * 2021-06-07 2024-08-15 Plexium, Inc. Transfer dispensers for assay devices with bead size exclusion
DE102021208831A1 (de) * 2021-08-12 2023-02-16 Robert Bosch Gesellschaft mit beschränkter Haftung Mikrofluidische Vorrichtung und Verfahren zu ihrem Betrieb
US20230139871A1 (en) * 2021-11-02 2023-05-04 Terumo Bct, Inc. Systems and Methods For Using Microfluidic Devices With Apheresis Systems
US11892445B2 (en) 2021-12-08 2024-02-06 Western Digital Technologies, Inc. Devices, systems, and methods of using smart fluids to control translocation speed through a nanopore
US12487229B2 (en) 2021-12-08 2025-12-02 Western Digital Technologies, Inc. Devices, systems, and methods of using smart fluids to control molecule speeds
WO2023230229A1 (en) * 2022-05-27 2023-11-30 Bendbio, Inc. Systems and methods for filtration
JP2024013994A (ja) * 2022-07-21 2024-02-01 株式会社Ｓｃｒｅｅｎホールディングス 流路チップ
US11821828B1 (en) * 2022-12-20 2023-11-21 Kuwait University System and method for determining physical stability of dispersed particles in flowing liquid suspensions
US12461064B2 (en) 2023-06-23 2025-11-04 Western Digital Technologies, Inc. Magnetic control of molecule translocation speed through a nanopore
CN121752363A (zh) * 2023-07-18 2026-03-27 波特尔生物技术有限公司 用于细胞内递送的离心装置和方法
EP4574969A1 (en) * 2023-12-22 2025-06-25 Sartorius Stedim Biotech GmbH A method of producing differentiated cells from pluripotent stem cells, cell populations obtained by the method, corresponding pharmaceutical compositions and a system for producing differentiated cells from pluripotent stem cells
WO2025247997A1 (en) * 2024-05-29 2025-12-04 Sartorius Stedim FMT S.A.S. Fluidic modules comprising membranes and associated methods
CN118636420B (zh) * 2024-06-18 2025-02-25 东莞市睿欣环保材料有限公司 一种环保哑光触感膜及其生产方法
CN118914015B (zh) * 2024-07-30 2025-09-09 中国石油大学(北京) 一种分散体系在多孔介质中孔隙尺寸下滞留率的测定方法

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4422939A (en) * 1979-11-07 1983-12-27 Texas Medical Products, Inc. Blood and perfusate filter
DE3546091A1 (de) 1985-12-24 1987-07-02 Kernforschungsz Karlsruhe Querstrom-mikrofilter
US5427663A (en) 1993-06-08 1995-06-27 British Technology Group Usa Inc. Microlithographic array for macromolecule and cell fractionation
US5601711A (en) * 1994-10-31 1997-02-11 Gelman Sciences Inc. Selective separation filter device
US5715946A (en) * 1995-06-07 1998-02-10 Reichenbach; Steven H. Method and apparatus for sorting particles suspended in a fluid
US6635430B1 (en) * 1999-07-16 2003-10-21 Dupont Pharmaceuticals Company Filtrate plate device and reversible-well plate device
CN2411833Y (zh) * 2000-03-31 2000-12-27 新汶矿业集团有限责任公司莱芜医院 简易液体过滤器
EP1343800A4 (en) 2000-12-18 2005-06-29 Univ Princeton FRACTIONATION OF MACROMOLECULES BY ELECTROPHORESIS IN ASYMMETRIC PULSE FIELD
US7597791B2 (en) 2001-10-19 2009-10-06 The Trustees Of Princeton University Method and apparatus for generating electric fields and flow distributions for rapidly separating molecules
JP2004042012A (ja) * 2001-10-26 2004-02-12 Nec Corp 分離装置、分析システム、分離方法および分離装置の製造方法
US7318902B2 (en) 2002-02-04 2008-01-15 Colorado School Of Mines Laminar flow-based separations of colloidal and cellular particles
WO2003085379A2 (en) 2002-04-01 2003-10-16 Fluidigm Corporation Microfluidic particle-analysis systems
US7455770B2 (en) * 2002-09-09 2008-11-25 Cytonome, Inc. Implementation of microfluidic components in a microfluidic system
CA2500392C (en) * 2002-09-27 2012-11-27 The General Hospital Corporation Microfluidic device for cell separation and uses thereof
EP1585583B1 (en) 2002-10-23 2010-04-07 The Trustees of Princeton University Method for continuous particle separation using obstacle arrays asymmetrically aligned to fields
JP2004354364A (ja) * 2002-12-02 2004-12-16 Nec Corp 微粒子操作ユニット、それを搭載したチップと検出装置、ならびにタンパク質の分離、捕獲、および検出方法
JP2004228382A (ja) 2003-01-23 2004-08-12 Nikon Corp 露光装置
DE10313201A1 (de) * 2003-03-21 2004-10-07 Steag Microparts Gmbh Mikrostrukturierte Trennvorrichtung und mikrofluidisches Verfahren zum Abtrennen von flüssigen Bestandteilen aus einer Flüssigkeit, die Partikel enthält
US7291450B2 (en) 2003-03-28 2007-11-06 Smith & Nephew, Inc. Preparation of a cell concentrate from a physiological solution
WO2004113877A1 (en) 2003-06-13 2004-12-29 The General Hospital Corporation Microfluidic systems for size based removal of red blood cells and platelets from blood
JP2005007352A (ja) 2003-06-20 2005-01-13 Sharp Corp 粒子の分離方法及び分離装置並びに検出装置
US20060046305A1 (en) * 2003-10-15 2006-03-02 National University Of Singapore Method and apparatus for detecting analyte with filter
US7790039B2 (en) * 2003-11-24 2010-09-07 Northwest Biotherapeutics, Inc. Tangential flow filtration devices and methods for stem cell enrichment
JP2005205387A (ja) 2004-01-24 2005-08-04 Minoru Seki 連続粒子分級方法
US7575681B2 (en) * 2004-07-06 2009-08-18 Schlumberger Technology Corporation Microfluidic separator
US20060204400A1 (en) 2004-11-24 2006-09-14 Christoph Blattert Process for separation of dispersions and an apparatus
JP2006263693A (ja) 2005-03-22 2006-10-05 Minoru Seki 微粒子の連続分離機構及び装置
US20070196820A1 (en) * 2005-04-05 2007-08-23 Ravi Kapur Devices and methods for enrichment and alteration of cells and other particles
EP1887021A4 (en) 2005-05-17 2010-02-03 Asahi Glass Co Ltd HARDENABLE COMPOSITION AND NEW ADAMANTAN COMPOUND
JP2007021465A (ja) 2005-07-12 2007-02-01 Minoru Seki 粒子を連続的に濃縮・分離するための流路構造および方法
US20070059774A1 (en) * 2005-09-15 2007-03-15 Michael Grisham Kits for Prenatal Testing
JP2007175684A (ja) 2005-12-26 2007-07-12 Minoru Seki 微粒子の濃縮・分級のための流路構造および方法
US7735652B2 (en) 2006-06-01 2010-06-15 The Trustees Of Princeton University Apparatus and method for continuous particle separation
WO2008024070A1 (en) * 2006-08-22 2008-02-28 Agency For Science, Technology And Research Microfluidic filtration unit, device and methods thereof
US7718420B2 (en) * 2006-10-10 2010-05-18 Postech Academy-Industry Foundation Microfluidic biochip for blood typing based on agglutination reaction
KR100843339B1 (ko) 2006-12-07 2008-07-03 한국전자통신연구원 혈액 중의 혈장 분리를 위하여 마이크로채널을 이용한혈장분리기 및 이에 의한 혈장분리방법
US20080290037A1 (en) * 2007-05-23 2008-11-27 Applera Corporation Methods and Apparatuses for Separating Biological Particles
FR2931085B1 (fr) * 2008-05-13 2011-05-27 Commissariat Energie Atomique Procede de tri de particules ou d'amas de particules dans un fluide circulant dans un canal
RU87084U1 (ru) * 2009-06-16 2009-09-27 Закрытое акционерное общество Научно-производственный комплекс "КБ ВЗЛЕТ" Фильтр для вакуумируемого кардиотомического резервуара
AU2010336424B2 (en) 2009-12-23 2013-06-13 Cytovera, Inc. A system and method for particle filtration

Also Published As

Publication number Publication date
JP5624629B2 (ja) 2014-11-12
EP2516320A1 (en) 2012-10-31
WO2011079217A1 (en) 2011-06-30
JP2015062414A (ja) 2015-04-09
US20140190903A1 (en) 2014-07-10
IL220274A0 (en) 2012-07-31
RU2539989C2 (ru) 2015-01-27
RU2012131424A (ru) 2014-01-27
KR20120117834A (ko) 2012-10-24
JP2013515599A (ja) 2013-05-09
CN102791616A (zh) 2012-11-21
CA2785390C (en) 2016-02-09
DOP2012000181A (es) 2012-12-15
CN102791616B (zh) 2015-07-29
MX2012007372A (es) 2012-10-05
AU2010336424B2 (en) 2013-06-13
AU2010336424A1 (en) 2012-08-02
US8679751B2 (en) 2014-03-25
BR112012018376A2 (pt) 2017-10-10
MX344460B (es) 2016-12-14
US20120258459A1 (en) 2012-10-11
US9174212B2 (en) 2015-11-03
TWI566793B (zh) 2017-01-21
CA2785390A1 (en) 2011-06-30
EP2516320A4 (en) 2015-03-04
SG181676A1 (en) 2012-07-30
TW201132371A (en) 2011-10-01
KR101443133B1 (ko) 2014-11-03
IL220274A (en) 2016-10-31

Similar Documents

Publication Publication Date Title
CR20140234A (es) Carenado de carro inferior para remolques
BRPI1006041A2 (pt) conjunto, sistema e métodos para filtrar líquidos
BRPI0922018A2 (pt) métodos implementado por computador e sistema configurado para gerar imagens relativas a uma região subterrânea.
CR20130576A (es) Sistema de enfriamiento de gas de síntesis y método de operación
BRPI0917591A2 (pt) sistema para gerar uma imagem e método para gerar uma imagem
BRPI0818708A2 (pt) Aparelho de interface eletrônica e método e sistema para produção do mesmo
BRPI0911922A2 (pt) sistema de entrada interativo e conjunto de iluminação para o mesmo
BRPI0810709A2 (pt) método e sistema implementados por computador e mídia legível por computador
BR112014012419A2 (pt) método implementado por computador e sistema
BR112013030471A2 (pt) método implementado por computador e sistema.
BR112012001170A2 (pt) método e sistema para criar uma pressão de solicitação negativa
BRPI1006434A2 (pt) encosto para um sistema de ressuscitação cardiopulmonar automatizado e sistema de ressuscitação cardiopulmonar automatizado
BR112013008644A2 (pt) dispositivo, sistema e método para produzir um efeito visual magneticamente induzido
BRPI0920286A2 (pt) método e sistema para identificar um item e utilização do sistema
CL2011001271A1 (es) Sistema autonomo de navegacion y metodo para plataforma maniobrable que comprende un modulo de conocimiento de la situacion y un modulo de decision
BR112013032183A2 (pt) sistema e método de avaliação de recursos
WO2013048154A3 (en) Group-wise device management system and method
BR112015002550A2 (pt) sistema para inspeção e monitoramento de uma superfície interna de uma tubulação e método de inspeção e monitoramento de uma superfície interna de uma tubulação.
BRPI0819876A2 (pt) Sistema de enumeração e método para exibição de led.
CO6970563A2 (es) Sistema y métodos para el aprendizaje de idiomas
BRPI0924874A2 (pt) Método e dispositivo para tratamento de exceções no sistema incorporado
BR112013032548A2 (pt) sistema de pilhas de combustível e método para controlá-lo
CL2011002478A1 (es) Metodo y un sistema para controlar el uso de un dispositivo electronico al menos por un usuario que comprende verificar si al menos una condicion restrictiva relacionada al uso de dicho dispositivo ha sido satisfecha.
EP2821668A4 (en) VIBRATING INSULATING DEVICE AND SYSTEM THEREWITH
WO2014093534A3 (en) Data sharing system for aircraft training