CR20140042A - Indazoles - Google Patents
IndazolesInfo
- Publication number
- CR20140042A CR20140042A CR20140042A CR20140042A CR20140042A CR 20140042 A CR20140042 A CR 20140042A CR 20140042 A CR20140042 A CR 20140042A CR 20140042 A CR20140042 A CR 20140042A CR 20140042 A CR20140042 A CR 20140042A
- Authority
- CR
- Costa Rica
- Prior art keywords
- indazoles
- compounds
- formula
- relates
- present
- Prior art date
Links
- BAXOFTOLAUCFNW-UHFFFAOYSA-N 1H-indazole Chemical compound C1=CC=C2C=NNC2=C1 BAXOFTOLAUCFNW-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Ophthalmology & Optometry (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Neurosurgery (AREA)
- Communicable Diseases (AREA)
- Endocrinology (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Reproductive Health (AREA)
- Toxicology (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Psychiatry (AREA)
- Child & Adolescent Psychology (AREA)
Abstract
La presente invención se refiere a los compuestos de fórmula (I):
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161512144P | 2011-07-27 | 2011-07-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CR20140042A true CR20140042A (es) | 2014-03-19 |
Family
ID=46826868
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CR20140042A CR20140042A (es) | 2011-07-27 | 2014-01-27 | Indazoles |
Country Status (30)
| Country | Link |
|---|---|
| US (2) | US8575336B2 (es) |
| EP (1) | EP2736907B1 (es) |
| JP (1) | JP5579351B1 (es) |
| KR (1) | KR20140026627A (es) |
| CN (1) | CN103717599B (es) |
| AP (1) | AP2014007372A0 (es) |
| AR (1) | AR087348A1 (es) |
| AU (1) | AU2012288491A1 (es) |
| BR (1) | BR112014001801A2 (es) |
| CA (1) | CA2841882A1 (es) |
| CL (1) | CL2014000122A1 (es) |
| CO (1) | CO6862160A2 (es) |
| CR (1) | CR20140042A (es) |
| CU (1) | CU20140009A7 (es) |
| DO (1) | DOP2014000016A (es) |
| EA (1) | EA201490357A1 (es) |
| EC (1) | ECSP14013222A (es) |
| GT (1) | GT201400016A (es) |
| IL (1) | IL230662A0 (es) |
| MA (1) | MA35285B1 (es) |
| MD (1) | MD20140002A2 (es) |
| MX (1) | MX2014001004A (es) |
| NI (1) | NI201400005A (es) |
| PE (1) | PE20141059A1 (es) |
| PH (1) | PH12014500199A1 (es) |
| TN (1) | TN2014000033A1 (es) |
| TW (1) | TWI462922B (es) |
| UA (1) | UA108442C2 (es) |
| UY (1) | UY34220A (es) |
| WO (1) | WO2013014567A1 (es) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8575336B2 (en) | 2011-07-27 | 2013-11-05 | Pfizer Limited | Indazoles |
| EP3143021B1 (en) * | 2014-05-14 | 2019-06-12 | Pfizer Inc | Pyrazolopyridines and pyrazolopyrimidines |
| WO2016139212A1 (en) | 2015-03-04 | 2016-09-09 | F. Hoffmann-La Roche Ag | Triazolopyridine compounds and methods of use thereof |
| SG11201707752SA (en) | 2015-04-22 | 2017-11-29 | Rigel Pharmaceuticals Inc | Pyrazole compounds and method for making and using the compounds |
| EP3371184A1 (en) | 2015-11-03 | 2018-09-12 | Topivert Pharma Limited | 4,5,6,7-tetrahydro-1h-imidazo[4,5-c]pyridine and 1,4,5,6,7,8-hexahydroimidazo[4,5-d]azepine derivatives as janus kinase inhibitors |
| KR20180073687A (ko) | 2015-11-03 | 2018-07-02 | 세라밴스 바이오파마 알앤디 아이피, 엘엘씨 | 호흡기 질환의 치료를 위한 jak 키나제 저해제 화합물 |
| ES2840650T3 (es) | 2015-11-03 | 2021-07-07 | Topivert Pharma Ltd | Derivados de 4,5,6,7-tetrahidro-1h-imidazo[4,5-c]piridina y 1,4,5,6,7,8-hexahidroimidazo[4,5-d]azepina como inhibidores de la quinasa janus |
| TW201720828A (zh) | 2015-11-23 | 2017-06-16 | 赫孚孟拉羅股份公司 | 治療性化合物及組合物以及其使用方法 |
| WO2017096262A1 (en) | 2015-12-04 | 2017-06-08 | Jomoco, Corp. | Compositions and methods to mitigate or prevent an immune response to an immunogenic therapeutic molecule in non-human primates |
| EP3416967B1 (en) | 2016-02-18 | 2022-02-09 | F. Hoffmann-La Roche AG | Therapeutic compounds, compositions and methods of use thereof |
| WO2017191098A1 (en) | 2016-05-05 | 2017-11-09 | F. Hoffmann-La Roche Ag | Pyrazole derivatives, compositions and therapeutic use thereof |
| RU2743170C2 (ru) * | 2016-06-01 | 2021-02-15 | Байер Энимал Хелс Гмбх | Замещенные индазолы, пригодные для лечения и предупреждения аллергических и/или воспалительных заболеваний у животных |
| JP7050761B2 (ja) | 2016-09-06 | 2022-04-08 | エフ．ホフマン－ラ ロシュ アーゲー | ８－（アゼチジン－１－イル）－［１，２，４］トリアゾロ［１，５－ａ］ピリジニル化合物、組成物及びその使用方法 |
| CR20190310A (es) | 2016-12-29 | 2019-08-21 | Hoffmann La Roche | Compuestos de pirazolopirimidina y métodos de uso de los mismos |
| EA037748B1 (ru) | 2017-03-09 | 2021-05-18 | ТЕРЕВАНС БАЙОФАРМА Ар энд Ди АйПи, ЭлЭлСи | Конденсированные имидазо-пиперидиновые ингибиторы jak |
| JP2020510061A (ja) | 2017-03-14 | 2020-04-02 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | ピラゾロクロロフェニル化合物、組成物及びその使用方法 |
| AR111495A1 (es) | 2017-05-01 | 2019-07-17 | Theravance Biopharma R&D Ip Llc | Compuestos de imidazo-piperidina fusionada como inhibidores de jak |
| SG11201909019SA (en) | 2017-05-01 | 2019-10-30 | Theravance Biopharma R&D Ip Llc | Methods of treatment using a jak inhibitor compound |
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| BR112021004087A2 (pt) * | 2018-09-04 | 2021-05-25 | Theravance Biopharma R&D Ip, Llc | processo para preparar inibidores de jak e seus intermediários |
| KR102826491B1 (ko) * | 2018-09-04 | 2025-06-27 | 세라밴스 바이오파마 알앤디 아이피, 엘엘씨 | Jak 억제제로서 디메틸 아미노 아제티딘 아마이드 |
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| US5376645A (en) | 1990-01-23 | 1994-12-27 | University Of Kansas | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
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| WO2000035298A1 (en) | 1996-11-27 | 2000-06-22 | Wm. Wrigley Jr. Company | Chewing gum containing medicament active agents |
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