CR20140412A - Inhibidores de la metalproteinasa matriz - Google Patents

Inhibidores de la metalproteinasa matriz

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Publication number
CR20140412A
CR20140412A CR20140412A CR20140412A CR20140412A CR 20140412 A CR20140412 A CR 20140412A CR 20140412 A CR20140412 A CR 20140412A CR 20140412 A CR20140412 A CR 20140412A CR 20140412 A CR20140412 A CR 20140412A
Authority
CR
Costa Rica
Prior art keywords
inhibitors
matrix
metalproteinase
carboxylic acids
present
Prior art date
Application number
CR20140412A
Other languages
English (en)
Inventor
Viswajanani J Sattigeri
Venkata P Palle
Manoj Kumar Khera
Ranadheer Reddy
Manoj Kumar Towari
Ajay Soni
Abdul Rehnian Abdul Rauf
Sony Joseph
Arpita Musib
Sunanda G Dastidar
Punit Kumar Srivastava
Original Assignee
Ranbaxy Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Lab Ltd filed Critical Ranbaxy Lab Ltd
Publication of CR20140412A publication Critical patent/CR20140412A/es

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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/4035—Isoindoles, e.g. phthalimide
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  • Thiazole And Isothizaole Compounds (AREA)

Abstract

El presente invento se relacion con ácidos carboxílicos sustituidos mediante B-hidroxi y amino, que actúan como inhibidores de la metaloproteasa matriz, ácidos carboxílicos B-hidroxi diastereoméricamente puros, procesos correspondientes para la síntesis de composiciones farmacéuticas que contienen los compuestos del presente invento.
CR20140412A 2006-08-22 2014-09-08 Inhibidores de la metalproteinasa matriz CR20140412A (es)

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PCT/IB2007/053340 WO2008023336A2 (en) 2006-08-22 2007-08-21 Matrix metalloproteinase inhibitors

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CA2661299A1 (en) 2008-02-28
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AU2007287230A1 (en) 2008-02-28
US8507670B2 (en) 2013-08-13
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NZ574905A (en) 2011-12-22
US20130302378A1 (en) 2013-11-14
SI2074093T1 (sl) 2012-12-31
EA016567B1 (ru) 2012-05-30
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US8816073B2 (en) 2014-08-26
HK1135684A1 (en) 2010-06-11
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EP2474531A2 (en) 2012-07-11
WO2008023336A2 (en) 2008-02-28
AP2690A (en) 2013-07-15
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TW201336829A (zh) 2013-09-16
AR063945A1 (es) 2009-03-04
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GEP20125458B (en) 2012-03-26
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