CR20160155A - Tienouracilcarboxamidas cíclicas y usos de las mismas - Google Patents

Tienouracilcarboxamidas cíclicas y usos de las mismas

Info

Publication number
CR20160155A
CR20160155A CR20160155A CR20160155A CR20160155A CR 20160155 A CR20160155 A CR 20160155A CR 20160155 A CR20160155 A CR 20160155A CR 20160155 A CR20160155 A CR 20160155A CR 20160155 A CR20160155 A CR 20160155A
Authority
CR
Costa Rica
Prior art keywords
prevention
treatment
tienouracilcarboxamidas
same
diseases
Prior art date
Application number
CR20160155A
Other languages
English (en)
Inventor
Michael Härter
Martina Delbeck
Bernd Kalthof
Klemens Lustig
Niels Lindner
Raimund Kast
Pierre Wasnaire
Frank Süssmeier
Original Assignee
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Pharma AG filed Critical Bayer Pharma AG
Publication of CR20160155A publication Critical patent/CR20160155A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La presente solicitud se relaciona con novedosos derivados de 2,4-dioxo-1,2,3,4-tetrahidrotieno[2,3-d]pirimidina-6-carboxamida ("tienouracil"-carboxamidas), con procesos para su preparación, con su uso solo o en combinaciones para el tratamiento y/o prevención 5 de enfermedades y con su uso para la preparación de medicamentos para el tratamiento y/o prevención de enfermedades, en particular para el tratamiento y/o prevención de trastornos pulmonares y cardiovasculares.
CR20160155A 2013-10-07 2016-04-04 Tienouracilcarboxamidas cíclicas y usos de las mismas CR20160155A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13187487 2013-10-07
EP14152518 2014-01-24
PCT/EP2014/071113 WO2015052065A1 (de) 2013-10-07 2014-10-02 Cyclische thienouracil-carboxamide und ihre verwendung

Publications (1)

Publication Number Publication Date
CR20160155A true CR20160155A (es) 2016-07-21

Family

ID=51655757

Family Applications (1)

Application Number Title Priority Date Filing Date
CR20160155A CR20160155A (es) 2013-10-07 2016-04-04 Tienouracilcarboxamidas cíclicas y usos de las mismas

Country Status (24)

Country Link
US (2) US9604996B2 (es)
EP (1) EP3055313B1 (es)
JP (1) JP2016532721A (es)
KR (1) KR20160065957A (es)
CN (1) CN105793267B (es)
AP (1) AP2016009128A0 (es)
AU (1) AU2014334040A1 (es)
BR (1) BR112016007238A2 (es)
CA (1) CA2926223A1 (es)
CR (1) CR20160155A (es)
CU (1) CU20160044A7 (es)
DO (1) DOP2016000076A (es)
EA (1) EA201600318A1 (es)
ES (1) ES2659043T3 (es)
IL (1) IL244751A0 (es)
MX (1) MX2016004250A (es)
NI (1) NI201600047A (es)
PE (1) PE20160562A1 (es)
PH (1) PH12016500608A1 (es)
SG (1) SG11201602397XA (es)
TN (1) TN2016000121A1 (es)
TW (1) TW201607950A (es)
UY (1) UY35771A (es)
WO (1) WO2015052065A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI3215498T1 (sl) * 2014-11-03 2018-11-30 Bayer Pharma Aktiengesellschaft Hidroksialkil-substituirani derivati feniltriazola in njihove uporabe
UY36586A (es) * 2015-03-26 2016-10-31 Bayer Pharma AG Heterociclilmetiltienouracilos y uso de los mismos
KR20190049691A (ko) * 2016-07-07 2019-05-09 카듀리온 파마슈티칼스, 엘엘씨 심부전의 치료 방법
WO2018041771A1 (de) 2016-09-02 2018-03-08 Bayer Pharma Aktiengesellschaft (1-methylcyclopropyl)methyl-substituierte thienouracile und ihre verwendung
CA3037642A1 (en) 2016-09-23 2018-03-29 Bayer Aktiengesellschaft N 3 -cyclically substituted thienouraciles and use thereof
US12569481B2 (en) 2020-06-12 2026-03-10 Vanderbilt University Methods of treatment for gastrointestinal motility disorders
AU2023325806A1 (en) * 2022-08-16 2025-03-06 Cms Research & Development Pte. Ltd. Salt type and crystal form of thienopyrimidinone derivative

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SE9702001D0 (sv) * 1997-05-28 1997-05-28 Astra Pharma Prod Novel compounds
DE19834047A1 (de) 1998-07-29 2000-02-03 Bayer Ag Substituierte Pyrazolderivate
DE19834044A1 (de) 1998-07-29 2000-02-03 Bayer Ag Neue substituierte Pyrazolderivate
DE69912618T2 (de) * 1998-08-28 2004-10-28 Astrazeneca Ab NEUE THIENO[2,3-d]PYRIMIDINDIONE, VERFAHREN FÜR IHRE HERSTELLUNG UND IHRE VERWENDUNG IN DER THERAPIE
DE19943636A1 (de) 1999-09-13 2001-03-15 Bayer Ag Neuartige Dicarbonsäurederivate mit pharmazeutischen Eigenschaften
DE19943635A1 (de) 1999-09-13 2001-03-15 Bayer Ag Neuartige Aminodicarbonsäurederivate mit pharmazeutischen Eigenschaften
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AR031176A1 (es) 2000-11-22 2003-09-10 Bayer Ag Nuevos derivados de pirazolpiridina sustituidos con piridina
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EP1370562A1 (en) * 2001-02-14 2003-12-17 Warner-Lambert Company LLC Thieno[2,3-d]pyrimidindione derivatives as matrix metalloproteinase inhibitors
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Also Published As

Publication number Publication date
CN105793267A (zh) 2016-07-20
CA2926223A1 (en) 2015-04-16
TN2016000121A1 (en) 2017-10-06
WO2015052065A1 (de) 2015-04-16
PH12016500608A1 (en) 2016-06-13
MX2016004250A (es) 2016-07-12
EP3055313B1 (de) 2017-11-22
SG11201602397XA (en) 2016-05-30
JP2016532721A (ja) 2016-10-20
CN105793267B (zh) 2018-02-06
US20170145029A1 (en) 2017-05-25
ES2659043T3 (es) 2018-03-13
IL244751A0 (en) 2016-04-21
US20160244461A1 (en) 2016-08-25
DOP2016000076A (es) 2016-05-15
TW201607950A (zh) 2016-03-01
AP2016009128A0 (en) 2016-04-30
KR20160065957A (ko) 2016-06-09
CU20160044A7 (es) 2016-09-30
NI201600047A (es) 2016-09-21
AU2014334040A1 (en) 2016-04-28
BR112016007238A2 (pt) 2017-08-01
US9604996B2 (en) 2017-03-28
EA201600318A1 (ru) 2016-09-30
PE20160562A1 (es) 2016-06-05
UY35771A (es) 2015-04-30
EP3055313A1 (de) 2016-08-17

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