AR031176A1 - Nuevos derivados de pirazolpiridina sustituidos con piridina - Google Patents

Nuevos derivados de pirazolpiridina sustituidos con piridina

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Publication number
AR031176A1
AR031176A1 ARP010105099A ARP010105099A AR031176A1 AR 031176 A1 AR031176 A1 AR 031176A1 AR P010105099 A ARP010105099 A AR P010105099A AR P010105099 A ARP010105099 A AR P010105099A AR 031176 A1 AR031176 A1 AR 031176A1
Authority
AR
Argentina
Prior art keywords
pirazolpiridina
piridine
substituted
new derivatives
pyridinyl
Prior art date
Application number
ARP010105099A
Other languages
English (en)
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10131987A external-priority patent/DE10131987A1/de
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of AR031176A1 publication Critical patent/AR031176A1/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
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    • A61P31/18—Antivirals for RNA viruses for HIV
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    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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    • A—HUMAN NECESSITIES
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychology (AREA)
  • Pulmonology (AREA)
  • Hospice & Palliative Care (AREA)
  • Virology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Addiction (AREA)
  • Gynecology & Obstetrics (AREA)
  • Tropical Medicine & Parasitology (AREA)

Abstract

La presente se refiere a nuevos derivados de pirazolpiridina de formula (1), en la que R1 representa 4-piridinilo o 3-piridinilo; R2 representa H, NH2 o halogeno; así como sales, isomeros e hidratos de los mismos como estimuladores de la guanilato ciclasa soluble y para la utilizacion como agentes para el tratamiento de desordenes cardiovasculares, hipertension desordenes tromboembolicos e isquemias, disfuncion sexual o inflamaciones así como para el tratamiento de desordenes del sistema nervioso central.
ARP010105099A 2000-11-22 2001-10-31 Nuevos derivados de pirazolpiridina sustituidos con piridina AR031176A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10057753 2000-11-22
DE10131987A DE10131987A1 (de) 2000-11-22 2001-07-02 Neue Pyridin-substituierte Pyrazolopyridinderivate

Publications (1)

Publication Number Publication Date
AR031176A1 true AR031176A1 (es) 2003-09-10

Family

ID=26007730

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP010105099A AR031176A1 (es) 2000-11-22 2001-10-31 Nuevos derivados de pirazolpiridina sustituidos con piridina

Country Status (28)

Country Link
US (1) US6693102B2 (es)
EP (1) EP1343786B1 (es)
JP (1) JP4246991B2 (es)
CN (1) CN1555374A (es)
AR (1) AR031176A1 (es)
AT (1) ATE298752T1 (es)
AU (1) AU2002220692A1 (es)
BG (1) BG107804A (es)
BR (1) BR0115477A (es)
CA (1) CA2429312C (es)
CZ (1) CZ294648B6 (es)
DK (1) DK1343786T3 (es)
EE (1) EE200300243A (es)
ES (1) ES2243598T3 (es)
HR (1) HRP20030489A2 (es)
HU (1) HUP0303283A2 (es)
IL (1) IL155974A0 (es)
MA (1) MA26060A1 (es)
MX (1) MXPA03004500A (es)
NO (1) NO20032299L (es)
NZ (1) NZ525963A (es)
PL (1) PL366090A1 (es)
PT (1) PT1343786E (es)
SI (1) SI1343786T1 (es)
SK (1) SK5912003A3 (es)
TW (1) TW582998B (es)
UY (1) UY27029A1 (es)
WO (1) WO2002042301A1 (es)

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DE102007042754A1 (de) * 2007-09-07 2009-03-12 Bayer Healthcare Ag Substituierte 6-Phenylnikotinsäuren und ihre Verwendung
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DE102008018675A1 (de) 2008-04-14 2009-10-15 Bayer Schering Pharma Aktiengesellschaft Oxo-heterocyclisch substituierte Carbonsäure-Derivate und ihre Verwendung
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DE102008030206A1 (de) 2008-06-25 2009-12-31 Bayer Schering Pharma Aktiengesellschaft 3-Cyanoalky- und 3-Hydroxyalkyl-Indole und ihre Verwendung
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