CR20230528A - Anticuerpo anti componente del complemento 1s (c1s) - Google Patents

Anticuerpo anti componente del complemento 1s (c1s)

Info

Publication number
CR20230528A
CR20230528A CR20230528A CR20230528A CR20230528A CR 20230528 A CR20230528 A CR 20230528A CR 20230528 A CR20230528 A CR 20230528A CR 20230528 A CR20230528 A CR 20230528A CR 20230528 A CR20230528 A CR 20230528A
Authority
CR
Costa Rica
Prior art keywords
individual
antibodies
complement
disorder
mediated disease
Prior art date
Application number
CR20230528A
Other languages
English (en)
Inventor
Hikaru Koga
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of CR20230528A publication Critical patent/CR20230528A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/32—Immunoglobulins specific features characterized by aspects of specificity or valency specific for a neo-epitope on a complex, e.g. antibody-antigen or ligand-receptor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C07K2317/524—CH2 domain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C07K2317/526—CH3 domain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/71—Decreased effector function due to an Fc-modification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CR20230528A 2021-04-15 2022-04-14 Anticuerpo anti componente del complemento 1s (c1s) CR20230528A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2021068964 2021-04-15
PCT/JP2022/017780 WO2022220275A1 (ja) 2021-04-15 2022-04-14 抗Ｃ１ｓ抗体

Publications (1)

Publication Number Publication Date
CR20230528A true CR20230528A (es) 2023-12-05

Family

ID=83640739

Family Applications (1)

Application Number Title Priority Date Filing Date
CR20230528A CR20230528A (es) 2021-04-15 2022-04-14 Anticuerpo anti componente del complemento 1s (c1s)

Country Status (15)

Country Link
US (1) US20240287163A1 (es)
EP (1) EP4324925A4 (es)
JP (2) JP7760581B2 (es)
KR (2) KR102967554B1 (es)
CN (1) CN117120615A (es)
AR (1) AR125344A1 (es)
AU (1) AU2022257471B2 (es)
CA (1) CA3213912A1 (es)
CL (1) CL2023003047A1 (es)
CO (1) CO2023012831A2 (es)
CR (1) CR20230528A (es)
IL (1) IL305041A (es)
MX (1) MX2023010764A (es)
PE (1) PE20242224A1 (es)
WO (1) WO2022220275A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2865158C (en) 2012-02-24 2022-11-01 Chugai Seiyaku Kabushiki Kaisha Antigen-binding molecule for promoting disappearance of antigen via fc.gamma.riib
SG11201508170TA (en) 2013-04-02 2015-11-27 Chugai Pharmaceutical Co Ltd Fc REGION VARIANT
EP4640703A3 (en) 2017-11-14 2026-04-08 Chugai Seiyaku Kabushiki Kaisha Anti-c1s antibodies and methods of use
CA3137649A1 (en) 2019-05-15 2020-11-19 Chugai Seiyaku Kabushiki Kaisha An antigen-binding molecule, a pharmaceutical composition, and a method
EP4644548A1 (en) 2022-12-27 2025-11-05 Chugai Seiyaku Kabushiki Kaisha Polypeptide with controlled association
WO2026076063A2 (en) * 2024-10-01 2026-04-09 Dianthus Therapeutics Opco, Inc. Compositions, doses, and methods for treatment of c1s mediated diseases and disorders

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CA3137649A1 (en) * 2019-05-15 2020-11-19 Chugai Seiyaku Kabushiki Kaisha An antigen-binding molecule, a pharmaceutical composition, and a method
BR112022006014A2 (pt) * 2019-10-16 2022-07-12 Chugai Pharmaceutical Co Ltd Anticorpo, composição farmacêutica e método

Also Published As

Publication number Publication date
CN117120615A (zh) 2023-11-24
MX2023010764A (es) 2023-09-22
BR112023015422A2 (pt) 2023-11-07
US20240287163A1 (en) 2024-08-29
EP4324925A4 (en) 2025-04-09
TW202304977A (zh) 2023-02-01
PE20242224A1 (es) 2024-11-19
AR125344A1 (es) 2023-07-05
JP7760581B2 (ja) 2025-10-27
KR102967554B1 (ko) 2026-05-20
WO2022220275A1 (ja) 2022-10-20
CO2023012831A2 (es) 2023-10-19
AU2022257471A1 (en) 2023-08-24
KR20230170017A (ko) 2023-12-18
CL2023003047A1 (es) 2024-03-15
KR20260088614A (ko) 2026-06-12
JPWO2022220275A1 (es) 2022-10-20
EP4324925A1 (en) 2024-02-21
JP2026012762A (ja) 2026-01-27
IL305041A (en) 2023-10-01
CA3213912A1 (en) 2022-10-20
AU2022257471A9 (en) 2024-07-18
AU2022257471B2 (en) 2026-01-22

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