CR5826A - Preparacion farmaceutica oral que comprende un compuesto de actividad antiulcerosa y procedimiento para su obtencion - Google Patents
Preparacion farmaceutica oral que comprende un compuesto de actividad antiulcerosa y procedimiento para su obtencionInfo
- Publication number
- CR5826A CR5826A CR5826A CR5826A CR5826A CR 5826 A CR5826 A CR 5826A CR 5826 A CR5826 A CR 5826A CR 5826 A CR5826 A CR 5826A CR 5826 A CR5826 A CR 5826A
- Authority
- CR
- Costa Rica
- Prior art keywords
- procedure
- coating
- excipient
- solution
- obtaining
- Prior art date
Links
- 230000000767 anti-ulcer Effects 0.000 title abstract 2
- 230000000694 effects Effects 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title 1
- 239000008183 oral pharmaceutical preparation Substances 0.000 title 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 3
- 239000011248 coating agent Substances 0.000 abstract 2
- 239000011247 coating layer Substances 0.000 abstract 2
- 238000000576 coating method Methods 0.000 abstract 2
- 229920001688 coating polymer Polymers 0.000 abstract 2
- 239000002702 enteric coating Substances 0.000 abstract 2
- 238000009505 enteric coating Methods 0.000 abstract 2
- 239000010410 layer Substances 0.000 abstract 2
- 238000002663 nebulization Methods 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pretreatment Of Seeds And Plants (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
un nucleo inerte, una capa activa soluble o de desintegracion rapida en agua obtenida a partir de una unica solucion-suspension acuosa o hidroalcoholica que comprende: un principio activo de actividad antiulcerosa de formula I, II o III, y por lo menos un excipiente, y una capa de recubrimiento externa gastrorresistente obtenida a partir de una solucion que comprende un polimero de recubrimiento enterico y por lo menos un excipiente. El procedimiento se lleva a cabo mediante un recubrimiento de los nucleos inertes mediante la nebulizacion de la unica suspension-solucion acuosa o hidroalcoholica, un secado de la capa activa formada durante la nebulizacion de la etapa anterior y un recubrimiento de los nucleos cargados mediante la nebulizacion de una solucion que comprende un polýimero de recubrimiento enterico con por lo menos un excipiente para obtener una capa de recubrimiento externa gastrorresistente.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES009701816A ES2137862B1 (es) | 1997-07-31 | 1997-07-31 | Preparacion farmaceutica oral que comprende un compuesto de actividad antiulcerosa y procedimiento para su obtencion. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CR5826A true CR5826A (es) | 1998-09-28 |
Family
ID=8300432
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CR5826A CR5826A (es) | 1997-07-31 | 1998-07-24 | Preparacion farmaceutica oral que comprende un compuesto de actividad antiulcerosa y procedimiento para su obtencion |
Country Status (33)
| Country | Link |
|---|---|
| US (1) | US20020098242A1 (es) |
| EP (1) | EP1010423B1 (es) |
| JP (1) | JP3961217B2 (es) |
| KR (1) | KR100591488B1 (es) |
| AR (1) | AR013242A1 (es) |
| AT (1) | ATE317688T1 (es) |
| AU (1) | AU751609B2 (es) |
| BG (1) | BG64967B1 (es) |
| CA (1) | CA2307037C (es) |
| CR (1) | CR5826A (es) |
| CZ (1) | CZ298700B6 (es) |
| DE (1) | DE69833490T2 (es) |
| DK (1) | DK1010423T3 (es) |
| ES (3) | ES2137862B1 (es) |
| GT (1) | GT199800113A (es) |
| HN (1) | HN1998000113A (es) |
| HR (1) | HRP20000053B1 (es) |
| HU (1) | HU230635B1 (es) |
| IL (1) | IL134158A (es) |
| MY (1) | MY121353A (es) |
| NO (1) | NO20000435L (es) |
| NZ (1) | NZ502590A (es) |
| PA (1) | PA8456401A1 (es) |
| PE (1) | PE105199A1 (es) |
| PL (1) | PL192961B1 (es) |
| PT (1) | PT1010423E (es) |
| RU (1) | RU2207114C2 (es) |
| SK (1) | SK284892B6 (es) |
| TR (1) | TR200000264T2 (es) |
| TW (1) | TW533201B (es) |
| UA (1) | UA66800C2 (es) |
| WO (1) | WO1999006032A2 (es) |
| ZA (1) | ZA986893B (es) |
Families Citing this family (66)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8071128B2 (en) | 1996-06-14 | 2011-12-06 | Kyowa Hakko Kirin Co., Ltd. | Intrabuccally rapidly disintegrating tablet and a production method of the tablets |
| US6096340A (en) * | 1997-11-14 | 2000-08-01 | Andrx Pharmaceuticals, Inc. | Omeprazole formulation |
| US6733778B1 (en) | 1999-08-27 | 2004-05-11 | Andrx Pharmaceuticals, Inc. | Omeprazole formulation |
| US6723342B1 (en) | 1999-02-08 | 2004-04-20 | Fmc Corporation | Edible coating composition |
| US6432448B1 (en) | 1999-02-08 | 2002-08-13 | Fmc Corporation | Edible coating composition |
| FR2793688B1 (fr) * | 1999-05-21 | 2003-06-13 | Ethypharm Lab Prod Ethiques | Microgranules gastroproteges, procede d'obtention et preparations pharmaceutiques |
| IL130602A0 (en) * | 1999-06-22 | 2000-06-01 | Dexcel Ltd | Stable benzimidazole formulation |
| US6228400B1 (en) * | 1999-09-28 | 2001-05-08 | Carlsbad Technology, Inc. | Orally administered pharmaceutical formulations of benzimidazole derivatives and the method of preparing the same |
| US6500462B1 (en) | 1999-10-29 | 2002-12-31 | Fmc Corporation | Edible MCC/PGA coating composition |
| IT1319655B1 (it) | 2000-11-15 | 2003-10-23 | Eurand Int | Microsfere di enzimi pancreatici con elevata stabilita' e relativometodo di preparazione. |
| EP1339395A2 (en) | 2000-11-28 | 2003-09-03 | Fmc Corporation | Edible pga (propylene glycol alginate) coating composition |
| US6932861B2 (en) | 2000-11-28 | 2005-08-23 | Fmc Corporation | Edible PGA coating composition |
| US9358214B2 (en) | 2001-10-04 | 2016-06-07 | Adare Pharmaceuticals, Inc. | Timed, sustained release systems for propranolol |
| KR100447085B1 (ko) * | 2001-11-08 | 2004-09-04 | 바램제약주식회사 | 마그네슘이온, 칼슘이온 또는 철이온이 고농도로 결합된알긴산의 제조 방법 |
| KR20050044545A (ko) * | 2001-11-21 | 2005-05-12 | 에자이 가부시키가이샤 | 산에 불안정한 생리활성 화합물을 함유하는 제제 조성물및 그 제법 |
| US20050163846A1 (en) * | 2001-11-21 | 2005-07-28 | Eisai Co., Ltd. | Preparation composition containing acid-unstable physiologically active compound, and process for producing same |
| US6663888B2 (en) | 2001-12-14 | 2003-12-16 | Eurand Pharmaceuticals Ltd. | Pulsatile release histamine H2 antagonist dosage form |
| US7732474B2 (en) * | 2002-08-02 | 2010-06-08 | Ratiopharm, Gmbh | Pharmaceutical preparation containing a benzimidazole compound mixed with microcrystalline cellulose and a method for its preparation |
| CA2503150A1 (en) * | 2002-10-31 | 2004-05-21 | Supergen, Inc. | Pharmaceutical formulations targeting specific regions of the gastrointestinal tract |
| US8367111B2 (en) | 2002-12-31 | 2013-02-05 | Aptalis Pharmatech, Inc. | Extended release dosage forms of propranolol hydrochloride |
| JP2006521366A (ja) * | 2003-03-28 | 2006-09-21 | シグモイド・バイオテクノロジーズ・リミテッド | シームレスマイクロカプセルを含む固形経口剤形 |
| JP2006528181A (ja) * | 2003-07-18 | 2006-12-14 | サンタラス インコーポレイティッド | 酸分泌を阻害するために有用な薬学的製剤ならびにそれらを作製および使用する方法 |
| ES2314646T3 (es) | 2004-03-22 | 2009-03-16 | Solvay Pharmaceuticals Gmbh | Composiciones farmaceuticas por via de productos que contienen lipasa , en particular de pancreatina, que contienen tensioactivos. |
| NZ549838A (en) * | 2004-03-26 | 2010-04-30 | Eisai R&D Man Co Ltd | Coated controlled-release preparation containing a gastric acid secretion inhibitor |
| CA2555114C (en) | 2004-03-31 | 2012-05-29 | Bpsi Holdings, Inc. | Enteric coatings for orally ingestible substrates |
| US8747895B2 (en) | 2004-09-13 | 2014-06-10 | Aptalis Pharmatech, Inc. | Orally disintegrating tablets of atomoxetine |
| CA2581816A1 (en) * | 2004-09-27 | 2006-04-06 | Sigmoid Biotechnologies Limited | Microcapsules comprising a methylxanthine and a corticosteroid |
| US9884014B2 (en) | 2004-10-12 | 2018-02-06 | Adare Pharmaceuticals, Inc. | Taste-masked pharmaceutical compositions |
| AU2005299490C1 (en) | 2004-10-21 | 2012-01-19 | Adare Pharmaceuticals, Inc. | Taste-masked pharmaceutical compositions with gastrosoluble pore-formers |
| BRPI0500586A (pt) * | 2005-02-21 | 2006-10-10 | Fundacao Oswaldo Cruz | composição farmacêutica, processo para preparar dita composição, uso da respectiva composição no tratamento da imunodeficiência causada por infecção pelo hiv e respectivo método de tratamento |
| WO2006111980A2 (en) * | 2005-04-20 | 2006-10-26 | Ideal Cures Pvt. Ltd. | Pva based film coating and film coating compositions |
| US9161918B2 (en) | 2005-05-02 | 2015-10-20 | Adare Pharmaceuticals, Inc. | Timed, pulsatile release systems |
| HUE031042T2 (en) | 2005-07-29 | 2017-06-28 | Abbott Laboratories Gmbh | Methods for producing pancreatin powder with low viral content |
| US11266607B2 (en) | 2005-08-15 | 2022-03-08 | AbbVie Pharmaceuticals GmbH | Process for the manufacture and use of pancreatin micropellet cores |
| US9198871B2 (en) | 2005-08-15 | 2015-12-01 | Abbott Products Gmbh | Delayed release pancreatin compositions |
| US20090148519A1 (en) * | 2005-09-29 | 2009-06-11 | Yasuhiro Zaima | Pulsed-release preparation having improved disintegration properties in vivo |
| US10072256B2 (en) | 2006-05-22 | 2018-09-11 | Abbott Products Gmbh | Process for separating and determining the viral load in a pancreatin sample |
| WO2008062320A2 (en) * | 2006-10-06 | 2008-05-29 | Eisai R&D Management Co., Ltd | Extended release formulations of a proton pump inhibitor |
| AU2008218595B2 (en) | 2007-02-20 | 2012-05-24 | Allergan Therapeutics LLC | Stable digestive enzyme compositions |
| EP2061440A2 (en) * | 2007-04-04 | 2009-05-27 | Sigmoid Pharma Limited | A pharmaceutical composition of tacrolimus |
| ES2963291T3 (es) | 2007-04-26 | 2024-03-26 | Sublimity Therapeutics Ltd | Fabricación de múltiples minicápsulas |
| CA2685591A1 (en) * | 2007-05-01 | 2008-11-06 | Sigmoid Pharma Limited | Pharmaceutical nimodipine compositions |
| JPWO2009069280A1 (ja) * | 2007-11-27 | 2011-04-07 | 大原薬品工業株式会社 | 造粒物の製造法 |
| WO2009109856A2 (en) | 2008-03-07 | 2009-09-11 | Axcan Pharma Inc. | Method for detecting infectious parvovirus in pharmaceutical preparations |
| US20110038933A1 (en) * | 2008-05-06 | 2011-02-17 | Dexcell Ltd. | Stable benzimidazole formulation |
| US8840934B2 (en) * | 2009-01-02 | 2014-09-23 | Rainbow Pharmaceutical Sa | Uses of ammonium chloride |
| ES2530049T3 (es) | 2009-05-18 | 2015-02-26 | Sigmoid Pharma Limited | Composición que comprende gotas de aceite |
| BR112012002963A2 (pt) | 2009-08-12 | 2017-10-24 | Sigmoid Pharma Ltd | composições imunomoduladoras compreendendo uma matriz de polímero e uma fase oleosa |
| KR101765357B1 (ko) | 2009-12-02 | 2017-08-04 | 아데어 파마수티컬스 에스.알.엘. | 펙소페나딘 마이크로캡슐 및 그것을 함유하는 조성물 |
| US20110217426A1 (en) * | 2010-03-04 | 2011-09-08 | Perry Stephen C | Enteric coating composition |
| UA111726C2 (uk) | 2010-10-01 | 2016-06-10 | Апталіс Фарма Лімітед | Препарат панкреліпази низької сили з кишковорозчинним покриттям |
| GB201020032D0 (en) | 2010-11-25 | 2011-01-12 | Sigmoid Pharma Ltd | Composition |
| WO2012166474A1 (en) * | 2011-06-01 | 2012-12-06 | Fmc Corporation | Controlled release solid dose forms |
| US10953025B2 (en) * | 2011-07-14 | 2021-03-23 | Able Cerebral, Llc | Composition, device and method for delayed and sustained release of brain energy molecules |
| EP2731593A4 (en) * | 2011-07-14 | 2015-07-01 | Able Cerebral Llc | COMPOSITION, DEVICE AND METHOD FOR DELAYED AND PROLONGED DELIVERY OF ENERGY MOLECULES TO THE BRAIN |
| MX351014B (es) | 2011-08-08 | 2017-09-28 | Aptalis Pharma Ltd | Metodo para la prueba de disolucion de composiciones solidas que contienen enzimas digestivas. |
| GB201212010D0 (en) | 2012-07-05 | 2012-08-22 | Sigmoid Pharma Ltd | Formulations |
| US10184121B2 (en) | 2013-06-28 | 2019-01-22 | Allergan Pharmaceuticals International Limited | Methods for removing viral contaminants from pancreatic extracts |
| CN106163544A (zh) | 2013-08-09 | 2016-11-23 | 阿勒根制药国际有限公司 | 适于经肠施用的消化酶组合物 |
| GB201319791D0 (en) | 2013-11-08 | 2013-12-25 | Sigmoid Pharma Ltd | Formulations |
| MX2014008314A (es) * | 2014-07-07 | 2016-01-06 | Andres Abelino Choza Romero | Procedimiento para mezclar sustancias, mediante nebulizacion. |
| TWI535784B (zh) | 2014-08-26 | 2016-06-01 | 財團法人工業技術研究院 | 剪切增稠配方、及包含其之複合材料 |
| EA036036B1 (ru) | 2014-11-07 | 2020-09-16 | Сигмойд Фарма Лимитед | Композиции, содержащие циклоспорин |
| US20170042806A1 (en) | 2015-04-29 | 2017-02-16 | Dexcel Pharma Technologies Ltd. | Orally disintegrating compositions |
| US10076494B2 (en) | 2016-06-16 | 2018-09-18 | Dexcel Pharma Technologies Ltd. | Stable orally disintegrating pharmaceutical compositions |
| CZ2017315A3 (cs) | 2017-06-02 | 2018-12-12 | Zentiva, K.S. | Dávkovací jednotka s PPI (inhibitory protonové pumpy) |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2799241A (en) * | 1949-01-21 | 1957-07-16 | Wisconsin Alumni Res Found | Means for applying coatings to tablets or the like |
| JPS517116A (en) * | 1974-06-11 | 1976-01-21 | Shinetsu Chemical Co | Choyoseihifukuyakuzaino seizohoho |
| CA1327010C (en) * | 1986-02-13 | 1994-02-15 | Tadashi Makino | Stabilized solid pharmaceutical composition containing antiulcer benzimidazole compound and its production |
| GB2189699A (en) * | 1986-04-30 | 1987-11-04 | Haessle Ab | Coated acid-labile medicaments |
| GB2189698A (en) * | 1986-04-30 | 1987-11-04 | Haessle Ab | Coated omeprazole tablets |
| US5026560A (en) * | 1987-01-29 | 1991-06-25 | Takeda Chemical Industries, Ltd. | Spherical granules having core and their production |
| KR930000861B1 (ko) * | 1990-02-27 | 1993-02-08 | 한미약품공업 주식회사 | 오메프라졸 직장투여 조성물 |
| SE9002043D0 (sv) * | 1990-06-07 | 1990-06-07 | Astra Ab | Improved method for synthesis |
| US5232706A (en) * | 1990-12-31 | 1993-08-03 | Esteve Quimica, S.A. | Oral pharmaceutical preparation containing omeprazol |
| YU48263B (sh) * | 1991-06-17 | 1997-09-30 | Byk Gulden Lomberg Chemische Fabrik Gmbh. | Postupak za dobijanje farmaceutskog preparata na bazi pantoprazola |
| ATE156707T1 (de) * | 1991-06-21 | 1997-08-15 | Ilsan Ilac Ve Hammaddeleri San | Neues galenisches verfahren für omeprazol enthaltende pellets |
| FR2692146B1 (fr) * | 1992-06-16 | 1995-06-02 | Ethypharm Sa | Compositions stables de microgranules d'omeprazole gastro-protégés et leur procédé d'obtention. |
| ES2145102T3 (es) * | 1993-09-09 | 2000-07-01 | Takeda Chemical Industries Ltd | Formulacion que comprende una sustancia antibacteriana y una sustancia antiulcerosa. |
| SE9402431D0 (sv) | 1994-07-08 | 1994-07-08 | Astra Ab | New tablet formulation |
| ES2094694B1 (es) * | 1995-02-01 | 1997-12-16 | Esteve Quimica Sa | Nueva formulacion farmaceuticamente estable de un compuesto de bencimidazol y su proceso de obtencion. |
| US5945124A (en) * | 1995-07-05 | 1999-08-31 | Byk Gulden Chemische Fabrik Gmbh | Oral pharmaceutical composition with delayed release of active ingredient for pantoprazole |
| SE9600070D0 (sv) * | 1996-01-08 | 1996-01-08 | Astra Ab | New oral pharmaceutical dosage forms |
| SE9600072D0 (sv) * | 1996-01-08 | 1996-01-08 | Astra Ab | New oral formulation of two active ingredients II |
-
1997
- 1997-07-31 ES ES009701816A patent/ES2137862B1/es not_active Expired - Fee Related
-
1998
- 1998-07-07 TW TW087110962A patent/TW533201B/zh not_active IP Right Cessation
- 1998-07-13 AU AU82173/98A patent/AU751609B2/en not_active Expired
- 1998-07-13 PT PT98932185T patent/PT1010423E/pt unknown
- 1998-07-13 TR TR2000/00264T patent/TR200000264T2/xx unknown
- 1998-07-13 SK SK103-2000A patent/SK284892B6/sk unknown
- 1998-07-13 CA CA002307037A patent/CA2307037C/en not_active Expired - Lifetime
- 1998-07-13 KR KR1020007001023A patent/KR100591488B1/ko not_active Expired - Lifetime
- 1998-07-13 DE DE69833490T patent/DE69833490T2/de not_active Expired - Lifetime
- 1998-07-13 PL PL338613A patent/PL192961B1/pl unknown
- 1998-07-13 CZ CZ20000344A patent/CZ298700B6/cs not_active IP Right Cessation
- 1998-07-13 ES ES98932185T patent/ES2256943T4/es not_active Expired - Lifetime
- 1998-07-13 WO PCT/ES1998/000204 patent/WO1999006032A2/es not_active Ceased
- 1998-07-13 EP EP98932185A patent/EP1010423B1/en not_active Revoked
- 1998-07-13 JP JP2000504847A patent/JP3961217B2/ja not_active Expired - Lifetime
- 1998-07-13 HR HR20000053A patent/HRP20000053B1/xx not_active IP Right Cessation
- 1998-07-13 AT AT98932185T patent/ATE317688T1/de active
- 1998-07-13 HU HU0002524A patent/HU230635B1/hu unknown
- 1998-07-13 RU RU2000104866/14A patent/RU2207114C2/ru not_active IP Right Cessation
- 1998-07-13 IL IL13415898A patent/IL134158A/en not_active IP Right Cessation
- 1998-07-13 UA UA2000020750A patent/UA66800C2/uk unknown
- 1998-07-13 DK DK98932185T patent/DK1010423T3/da active
- 1998-07-13 NZ NZ502590A patent/NZ502590A/en not_active IP Right Cessation
- 1998-07-22 AR ARP980103576A patent/AR013242A1/es unknown
- 1998-07-23 HN HN1998000113A patent/HN1998000113A/es unknown
- 1998-07-23 PE PE1998000660A patent/PE105199A1/es not_active Application Discontinuation
- 1998-07-24 CR CR5826A patent/CR5826A/es not_active Application Discontinuation
- 1998-07-27 GT GT199800113A patent/GT199800113A/es unknown
- 1998-07-28 MY MYPI98003435A patent/MY121353A/en unknown
- 1998-07-30 PA PA19988456401A patent/PA8456401A1/es unknown
- 1998-07-31 ZA ZA986893A patent/ZA986893B/xx unknown
-
1999
- 1999-01-27 ES ES009900157A patent/ES2156699B1/es not_active Expired - Fee Related
-
2000
- 2000-01-26 US US09/491,624 patent/US20020098242A1/en not_active Abandoned
- 2000-01-27 NO NO20000435A patent/NO20000435L/no not_active Application Discontinuation
- 2000-02-25 BG BG104193A patent/BG64967B1/bg unknown
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| Date | Code | Title | Description |
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| FA | Abandonment or withdrawal (granting procedure) |