CR6529A - Acidos 3-propil-gama-aminobutiricos mono y disustituidos - Google Patents

Acidos 3-propil-gama-aminobutiricos mono y disustituidos

Info

Publication number
CR6529A
CR6529A CR6529A CR6529A CR6529A CR 6529 A CR6529 A CR 6529A CR 6529 A CR6529 A CR 6529A CR 6529 A CR6529 A CR 6529A CR 6529 A CR6529 A CR 6529A
Authority
CR
Costa Rica
Prior art keywords
acids
disustituted
aminobutiric
propil
range
Prior art date
Application number
CR6529A
Other languages
English (en)
Inventor
Richard Belliotti Thomas
Stephen Briñas Justin
Victor Ekhato Ihoezo
Tobi Osuma Augustine
Michael Schelkun Robert
Bradley Schwarz Jacob
John Thorpe Andrew
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of CR6529A publication Critical patent/CR6529A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A61P25/10—Antiepileptics; Anticonvulsants for petit-mal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/08—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to hydrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/20—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/30—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and unsaturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/32—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

COMPUESTOS DE LA FORMULA I O UNA SAL FARMACEUTICAMENTE ACEPTABLE DE LOS MISMOS, EN LA CUAL R1 ES HIDROGENO, ALQUILO DE CADENA RECTA O RAMIFICADA DE 1 A 6 ATOMOS DE CARBONO O FENILO, R2 ES ALQUILO DE CADENA RECTA O RAMIFICADA DE 2 A 8 ATOMOS DE CARBONO, CICLOALQUILO, ALQUILALCOXI, OH DE ALQUILO, ALQUILFENILO, ALQUILFENOXI, FENILO O FENILO SUBSTITUIDO Y R3 ES ES ALQUILO DE CADENA RECTA O RAMIFICADA DE 1 A 6 ATOMOS DE CARBONO O FENILO CUANDO R2 ES METILO.
CR6529A 1999-06-10 2001-12-07 Acidos 3-propil-gama-aminobutiricos mono y disustituidos CR6529A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13848599P 1999-06-10 1999-06-10

Publications (1)

Publication Number Publication Date
CR6529A true CR6529A (es) 2003-11-25

Family

ID=22482232

Family Applications (1)

Application Number Title Priority Date Filing Date
CR6529A CR6529A (es) 1999-06-10 2001-12-07 Acidos 3-propil-gama-aminobutiricos mono y disustituidos

Country Status (43)

Country Link
EP (1) EP1192125B9 (es)
JP (1) JP3904452B2 (es)
KR (1) KR100694735B1 (es)
CN (2) CN1310872C (es)
AP (1) AP1397A (es)
AR (1) AR033335A1 (es)
AT (1) ATE419231T1 (es)
AU (1) AU776723C (es)
BG (1) BG65561B1 (es)
BR (1) BR0011727A (es)
CA (2) CA2689997A1 (es)
CO (1) CO5200791A1 (es)
CR (1) CR6529A (es)
CU (1) CU23101A3 (es)
CY (1) CY1108827T1 (es)
CZ (2) CZ300834B6 (es)
DE (1) DE60041256D1 (es)
DK (1) DK1192125T3 (es)
DZ (1) DZ3253A1 (es)
EA (1) EA004398B1 (es)
EE (1) EE200100672A (es)
ES (1) ES2317839T3 (es)
GE (1) GEP20074142B (es)
HK (1) HK1046401B (es)
HR (1) HRP20020025A2 (es)
HU (1) HUP0201601A3 (es)
IL (2) IL146969A0 (es)
IS (1) IS6181A (es)
MA (1) MA26804A1 (es)
ME (1) MEP44808A (es)
MX (1) MXPA01012319A (es)
NO (2) NO327746B1 (es)
NZ (1) NZ515668A (es)
OA (1) OA11962A (es)
PE (1) PE20010285A1 (es)
PT (1) PT1192125E (es)
RS (2) RS20090257A (es)
SI (1) SI1192125T1 (es)
SK (2) SK287247B6 (es)
TR (1) TR200103587T2 (es)
UA (1) UA72519C2 (es)
WO (1) WO2000076958A2 (es)
ZA (1) ZA200109711B (es)

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US7164034B2 (en) 1999-06-10 2007-01-16 Pfizer Inc. Alpha2delta ligands for fibromyalgia and other disorders
US6620829B2 (en) 2000-10-17 2003-09-16 Warner-Lambert Company Method of treating noninflammatory cartilage damage
WO2002100347A2 (en) * 2001-06-11 2002-12-19 Xenoport, Inc. Prodrugs of gaba analogs, compositions and uses thereof
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
ITMI20011308A1 (it) 2001-06-21 2002-12-21 Nicox Sa Farmaci per il dolore cronico
KR20040081478A (ko) 2002-01-31 2004-09-21 워너-램버트 캄파니 엘엘씨 이명을 치료하기 위한 알파 2 델타 리간드
NI200300043A (es) * 2002-03-28 2003-11-05 Warner Lambert Co AMINOACIDOS CON AFINIDAD POR LA PROTEINA a2DELTA.
US20030225149A1 (en) * 2002-04-30 2003-12-04 Blazecka Peter G. Process for preparing highly functionalized gamma-butyrolactams and gamma-amino acids
US7071339B2 (en) 2002-08-29 2006-07-04 Warner Lambert Company Llc Process for preparing functionalized γ-butyrolactones from mucohalic acid
ES2341240T3 (es) 2002-12-13 2010-06-17 Warner-Lambert Company Llc Ligando alfa-2-delta para tratar los sintomas del tracto urinario inferior.
EP1572187A1 (en) * 2002-12-13 2005-09-14 Warner-Lambert Company LLC Pregabalin and derivatives thereof for the treatment of fibromyalgia and other related disorders
CA2451267A1 (en) 2002-12-13 2004-06-13 Warner-Lambert Company Llc Pharmaceutical uses for alpha2delta ligands
KR20050085636A (ko) * 2002-12-13 2005-08-29 워너-램버트 캄파니 엘엘씨 섬유근육통 및 기타 질환의 치료를 위한 프레가발린 유도체
ITMI20022658A1 (it) 2002-12-17 2004-06-18 Nicox Sa Farmaci per il dolore cronico.
EP1680125A1 (en) * 2003-07-02 2006-07-19 Warner-Lambert Company LLC Combination of an allosteric inhibitor of matrix metalloproteinase-13 and a ligand to an alpha-2-delta receptor
MXPA06002789A (es) 2003-09-12 2006-06-14 Pfizer Combinaciones que comprenden ligandos alfa-2-delta.
WO2005030700A2 (en) * 2003-09-25 2005-04-07 Warner-Lambert Company Llc Amino acids with affinity for the alpha2delta-protein
CA2540247C (en) 2003-09-25 2011-01-25 Warner-Lambert Company Llc Prodrugs of amino acids with affinity for the .alpha.2.delta.-protein
WO2006043171A2 (en) * 2004-10-23 2006-04-27 Warner-Lambert Company Llc Methods of using alpha2delta-1 selective compounds
ES2530398T3 (es) * 2005-09-15 2015-03-02 Ucb Pharma Sa Pirrolidin-2-onas 4-sustituidas y su uso
US20070141684A1 (en) * 2005-12-21 2007-06-21 Pfizer Inc Preparation of gamma-amino acids having affinity for the alpha-2-delta protein
AR061728A1 (es) * 2006-06-30 2008-09-17 Pfizer Prod Inc Composicion para tratamiento usando compuestos selectivos alfa-2-delta-1
UA94979C2 (uk) 2006-12-22 2011-06-25 Рекордати Айеленд Лимитед КОМБІНОВАНА ТЕРАПІЯ ПОРУШЕНЬ НИЖНІХ СЕЧОВИВІДНИХ ШЛЯХІВ ЛІГАНДАМИ α2δ І НПЗП
WO2009136375A1 (en) * 2008-05-08 2009-11-12 Pfizer Inc Treatment of interstitial cystitis
EP2509596B1 (en) 2009-12-08 2019-08-28 Case Western Reserve University Gamma aminoacids for treating ocular disorders
CN101914031B (zh) * 2010-07-30 2013-08-28 中国广州分析测试中心 普瑞巴林衍生物及其应用
SI3364958T1 (sl) 2015-10-23 2023-05-31 Navitor Pharmaceuticals, Inc. Modulatorji interakcije sestrina in gator2 ter njihova uporaba
ES3040534T3 (en) 2017-04-26 2025-11-03 Navitor Pharm Inc Modulator of sestrin-gator2 interaction for use in the treatment of treatment-resistant depression
CA3117336A1 (en) 2018-10-24 2020-04-30 Navitor Pharmaceuticals, Inc. Polymorphs of (s)-2-amino-5,5-difluoro-4,4-dimethylpentanoic acid for use in modulating mtorc1
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ATE361909T1 (de) * 1996-10-23 2007-06-15 Warner Lambert Co Substituierte gamma-aminobuttersäurederivate als arzneimittel
DE69834204T2 (de) * 1997-10-27 2007-03-29 Warner-Lambert Co. Llc Zyklische aminosäuren und deren derivate als arzneimittel

Also Published As

Publication number Publication date
CO5200791A1 (es) 2002-09-27
IL146969A0 (en) 2002-08-14
BG106292A (bg) 2002-05-31
EA200101134A1 (ru) 2002-06-27
SK17642001A3 (sk) 2002-10-08
ES2317839T3 (es) 2009-05-01
IL146969A (en) 2008-03-20
ATE419231T1 (de) 2009-01-15
MEP44808A (en) 2011-02-10
AR033335A1 (es) 2003-12-17
HUP0201601A3 (en) 2002-11-28
HK1046401B (zh) 2005-12-02
GEP20074142B (en) 2007-07-10
AP1397A (en) 2005-04-19
PT1192125E (pt) 2009-03-05
WO2000076958A3 (en) 2001-04-12
HK1046401A1 (en) 2003-01-10
NO20015949L (no) 2001-12-05
NO20091094L (no) 2001-12-05
JP3904452B2 (ja) 2007-04-11
RS50352B (sr) 2009-11-10
HUP0201601A2 (en) 2002-10-28
AU776723C (en) 2005-06-02
BG65561B1 (bg) 2008-12-30
DZ3253A1 (fr) 2000-12-21
UA72519C2 (en) 2005-03-15
BR0011727A (pt) 2002-03-05
NO20015949D0 (no) 2001-12-05
CA2374755A1 (en) 2000-12-21
SK287399B6 (sk) 2010-08-09
ZA200109711B (en) 2003-03-20
CZ301608B6 (cs) 2010-04-28
PL352431A1 (en) 2003-08-25
SK287247B6 (sk) 2010-04-07
MA26804A1 (fr) 2004-12-20
CN1355784A (zh) 2002-06-26
CZ20014285A3 (cs) 2002-07-17
WO2000076958A2 (en) 2000-12-21
CY1108827T1 (el) 2014-04-09
NO327746B1 (no) 2009-09-14
CN1660779A (zh) 2005-08-31
KR20020009631A (ko) 2002-02-01
CA2374755C (en) 2010-03-30
OA11962A (en) 2006-04-17
MXPA01012319A (es) 2002-07-22
PE20010285A1 (es) 2001-03-22
AU5311900A (en) 2001-01-02
JP2003502308A (ja) 2003-01-21
CU23101A3 (es) 2005-12-20
HK1076626A1 (en) 2006-01-20
IS6181A (is) 2001-11-28
EP1192125B9 (en) 2009-09-16
SI1192125T1 (sl) 2009-04-30
DK1192125T3 (da) 2009-02-16
HRP20020025A2 (en) 2003-12-31
TR200103587T2 (tr) 2002-04-22
CA2689997A1 (en) 2000-12-21
CZ300834B6 (cs) 2009-08-19
KR100694735B1 (ko) 2007-03-14
EA004398B1 (ru) 2004-04-29
CN1196671C (zh) 2005-04-13
DE60041256D1 (de) 2009-02-12
EP1192125B1 (en) 2008-12-31
AP2002002388A0 (en) 2002-03-31
NZ515668A (en) 2004-02-27
AU776723B2 (en) 2004-09-16
CN1310872C (zh) 2007-04-18
RS20090257A (sr) 2010-03-02
YU87001A (sh) 2004-07-15
EE200100672A (et) 2003-02-17
EP1192125A2 (en) 2002-04-03

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