NO20064953L - Human GLP-1 mimetilegemer, sammensetninger, fremgangsmater og anvendelser - Google Patents
Human GLP-1 mimetilegemer, sammensetninger, fremgangsmater og anvendelserInfo
- Publication number
- NO20064953L NO20064953L NO20064953A NO20064953A NO20064953L NO 20064953 L NO20064953 L NO 20064953L NO 20064953 A NO20064953 A NO 20064953A NO 20064953 A NO20064953 A NO 20064953A NO 20064953 L NO20064953 L NO 20064953L
- Authority
- NO
- Norway
- Prior art keywords
- mimetic
- methods
- bodies
- compositions
- applications
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 101000788682 Homo sapiens GATA-type zinc finger protein 1 Proteins 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 101001032756 Rattus norvegicus Granzyme-like protein 1 Proteins 0.000 abstract 2
- 238000002360 preparation method Methods 0.000 abstract 2
- 102100025101 GATA-type zinc finger protein 1 Human genes 0.000 abstract 1
- 101710198884 GATA-type zinc finger protein 1 Proteins 0.000 abstract 1
- DTHNMHAUYICORS-KTKZVXAJSA-N Glucagon-like peptide 1 Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CC=1N=CNC=1)[C@@H](C)O)[C@@H](C)O)C(C)C)C1=CC=CC=C1 DTHNMHAUYICORS-KTKZVXAJSA-N 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 230000009261 transgenic effect Effects 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Toxicology (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Wood Science & Technology (AREA)
- Veterinary Medicine (AREA)
- General Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Biotechnology (AREA)
- Emergency Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Obesity (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Foreliggende oppfinnelse gjelder minst et nytt, humant GLP- I -Mimetistoff eller en spesifisert del eller variant derav, innbefattet isolerte nukleinsyrer som koder for minst et GLP- 1 -mimetistoff eller en spesifisert del eller variant derav, GLP- I -mimetistoff eller spesifiserte deler eller varianter derav, vektorer, vertsceller, transgene dyr eller planter og fremgangsmåter for fremstilling og anvendelse derav, innbefattet terapeutiske preparater, fremgangsmåter og innretninger.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55798304P | 2004-03-31 | 2004-03-31 | |
| US61298104P | 2004-09-24 | 2004-09-24 | |
| PCT/US2005/010456 WO2005097175A2 (en) | 2004-03-31 | 2005-03-28 | Human glp-1 mimetibodies, compositions, methods and uses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20064953L true NO20064953L (no) | 2006-12-18 |
Family
ID=35125618
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20064953A NO20064953L (no) | 2004-03-31 | 2006-10-30 | Human GLP-1 mimetilegemer, sammensetninger, fremgangsmater og anvendelser |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20070135338A1 (no) |
| EP (1) | EP1750754A4 (no) |
| JP (1) | JP2008537873A (no) |
| KR (1) | KR20070004078A (no) |
| AR (1) | AR049014A1 (no) |
| AU (1) | AU2005231359A1 (no) |
| BR (1) | BRPI0509528A (no) |
| CA (1) | CA2563379A1 (no) |
| CR (1) | CR8706A (no) |
| EA (2) | EA011583B1 (no) |
| IL (1) | IL178432A0 (no) |
| MX (1) | MXPA06011425A (no) |
| NO (1) | NO20064953L (no) |
| SG (1) | SG151315A1 (no) |
| TW (1) | TW200602491A (no) |
| WO (1) | WO2005097175A2 (no) |
| ZA (1) | ZA200709266B (no) |
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| ME01234B (me) * | 2004-10-25 | 2013-06-20 | Centocor Inc | Mimetička tijela koja vezuju receptore melanokortina, smjese, postupci i upotrebe |
| US7910101B2 (en) | 2004-10-25 | 2011-03-22 | Centocor, Inc. | Melanocortin receptor binding mimetibodies, compositions, methods and uses |
| KR20070090036A (ko) * | 2004-12-22 | 2007-09-04 | 센토코 인코포레이티드 | Glp-1 작용제, 조성물, 방법 및 용도 |
| TW200643033A (en) * | 2005-03-08 | 2006-12-16 | Chugai Pharmaceutical Co Ltd | Conjugate of water-soluble modified hyaluronic acid and glp-1 analogue |
| JP2008546373A (ja) * | 2005-03-28 | 2008-12-25 | セントカー・インコーポレーテツド | ヒトglp−1ミメティボディ、組成物、方法および用途 |
| US9284375B2 (en) * | 2005-04-15 | 2016-03-15 | Macrogenics, Inc. | Covalent diabodies and uses thereof |
| EP3479844B1 (en) | 2005-04-15 | 2023-11-22 | MacroGenics, Inc. | Covalent diabodies and uses thereof |
| US11254748B2 (en) | 2005-04-15 | 2022-02-22 | Macrogenics, Inc. | Covalent diabodies and uses thereof |
| US9963510B2 (en) * | 2005-04-15 | 2018-05-08 | Macrogenics, Inc. | Covalent diabodies and uses thereof |
| CA2658673A1 (en) * | 2005-07-27 | 2008-02-01 | Gerald J. Prud'homme | Composition and method for prevention and treatment of type i and type ii diabetes |
| PL1767545T3 (pl) | 2005-09-22 | 2010-04-30 | Biocompatibles Uk Ltd | Polipeptydy fuzyjne GLP-1 (glukagonopodobny peptyd-1) o zwiększonej odporności na peptydazy |
| WO2007067828A2 (en) * | 2005-10-24 | 2007-06-14 | Centocor, Inc. | Glp-2 mimetibodies, polypeptides, compositions, methods and uses |
| EP1968645A4 (en) * | 2005-12-22 | 2009-11-04 | Centocor Ortho Biotech Inc | HUMAN GLP-1 MIMETIC BODIES AND COMPOSITIONS FOR THE TREATMENT OF ADIPOSITAS AND RELATED DISEASES, METHODS AND APPLICATIONS |
| WO2007115148A2 (en) * | 2006-03-31 | 2007-10-11 | Centocor, Inc. | Human mimetic epo hinge core mimetibodies |
| ATE444741T1 (de) | 2006-05-10 | 2009-10-15 | Biocompatibles Uk Ltd | Glp-1 peptide enthaltende kugelförmige mikrokapseln, deren produktion und deren verwendung |
| AU2007275294A1 (en) * | 2006-07-18 | 2008-01-24 | Centocor, Inc. | Human GLP-1 mimetibodies, compositions, methods and uses |
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| ES2675730T3 (es) * | 2008-06-04 | 2018-07-12 | Macrogenics, Inc. | Anticuerpos con unión alterada a FcRn y métodos de uso de los mismos |
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| CN102256618A (zh) | 2008-10-17 | 2011-11-23 | 赛诺菲-安万特德国有限公司 | 胰岛素和glp-1激动剂的组合 |
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| CN111879948A (zh) | 2013-10-17 | 2020-11-03 | 综合医院公司 | 鉴定响应于用于自身免疫性疾病的治疗的受试者的方法以及用于治疗该疾病的组合物 |
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| TWI748945B (zh) | 2015-03-13 | 2021-12-11 | 德商賽諾菲阿凡提斯德意志有限公司 | 第2型糖尿病病患治療 |
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-
2005
- 2005-03-28 JP JP2007506454A patent/JP2008537873A/ja active Pending
- 2005-03-28 SG SG200902141-1A patent/SG151315A1/en unknown
- 2005-03-28 EA EA200601603A patent/EA011583B1/ru not_active IP Right Cessation
- 2005-03-28 EP EP05730437A patent/EP1750754A4/en not_active Withdrawn
- 2005-03-28 AU AU2005231359A patent/AU2005231359A1/en not_active Abandoned
- 2005-03-28 KR KR1020067022887A patent/KR20070004078A/ko not_active Ceased
- 2005-03-28 US US11/091,181 patent/US20070135338A1/en not_active Abandoned
- 2005-03-28 MX MXPA06011425A patent/MXPA06011425A/es not_active Application Discontinuation
- 2005-03-28 CA CA002563379A patent/CA2563379A1/en not_active Abandoned
- 2005-03-28 WO PCT/US2005/010456 patent/WO2005097175A2/en not_active Ceased
- 2005-03-28 BR BRPI0509528-0A patent/BRPI0509528A/pt not_active Application Discontinuation
- 2005-03-30 TW TW094109910A patent/TW200602491A/zh unknown
- 2005-03-31 AR ARP050101276A patent/AR049014A1/es unknown
- 2005-12-22 EA EA200702093A patent/EA200702093A1/ru unknown
-
2006
- 2006-10-03 IL IL178432A patent/IL178432A0/en unknown
- 2006-10-25 CR CR8706A patent/CR8706A/es not_active Application Discontinuation
- 2006-10-30 NO NO20064953A patent/NO20064953L/no not_active Application Discontinuation
-
2007
- 2007-10-26 ZA ZA200709266A patent/ZA200709266B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EA011583B1 (ru) | 2009-04-28 |
| JP2008537873A (ja) | 2008-10-02 |
| KR20070004078A (ko) | 2007-01-05 |
| ZA200709266B (en) | 2009-05-27 |
| IL178432A0 (en) | 2007-02-11 |
| BRPI0509528A (pt) | 2007-08-07 |
| EP1750754A4 (en) | 2010-09-22 |
| AU2005231359A1 (en) | 2005-10-20 |
| SG151315A1 (en) | 2009-04-30 |
| CR8706A (es) | 2009-01-16 |
| US20070135338A1 (en) | 2007-06-14 |
| WO2005097175A3 (en) | 2009-11-19 |
| TW200602491A (en) | 2006-01-16 |
| EP1750754A2 (en) | 2007-02-14 |
| MXPA06011425A (es) | 2007-03-12 |
| EA200702093A1 (ru) | 2009-06-30 |
| WO2005097175A2 (en) | 2005-10-20 |
| CA2563379A1 (en) | 2005-10-20 |
| AR049014A1 (es) | 2006-06-21 |
| EA200601603A1 (ru) | 2007-08-31 |
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