CR9183A - Tiazolidinonas metasustituidas, su preparacion y su uso como medicamento - Google Patents

Tiazolidinonas metasustituidas, su preparacion y su uso como medicamento

Info

Publication number
CR9183A
CR9183A CR9183A CR9183A CR9183A CR 9183 A CR9183 A CR 9183A CR 9183 A CR9183 A CR 9183A CR 9183 A CR9183 A CR 9183A CR 9183 A CR9183 A CR 9183A
Authority
CR
Costa Rica
Prior art keywords
thiazolidinones
preparation
metas
replaced
medicinal product
Prior art date
Application number
CR9183A
Other languages
English (en)
Inventor
Klaus Schulze Volker
Eis Knut
Wortmann Lars
Kosemund Dirk
Prien Olaf
Siemeister Gerhard
Hess-Stumpp Holger
Eberspacher Uwe
E A Brittain Dominic
Islam Imadul
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35895206&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CR9183(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE102004061503A external-priority patent/DE102004061503A1/de
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Publication of CR9183A publication Critical patent/CR9183A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/14—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)

Abstract

La invencion se relaciona con tiazolidinonas de la formula i como tambien con su preparacion y su uso como inhibidores de la polo-quinasa (PIK) para el tratamiento de diferentes enfermedades
CR9183A 2004-12-15 2007-06-13 Tiazolidinonas metasustituidas, su preparacion y su uso como medicamento CR9183A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102004061503A DE102004061503A1 (de) 2004-12-15 2004-12-15 Metasubstituierte Thiazolidinone, deren Herstellung und Verwendung als Arzneimittel
US63777704P 2004-12-22 2004-12-22

Publications (1)

Publication Number Publication Date
CR9183A true CR9183A (es) 2008-01-21

Family

ID=35895206

Family Applications (1)

Application Number Title Priority Date Filing Date
CR9183A CR9183A (es) 2004-12-15 2007-06-13 Tiazolidinonas metasustituidas, su preparacion y su uso como medicamento

Country Status (18)

Country Link
US (2) US20070015759A1 (es)
EP (1) EP1824834A1 (es)
JP (1) JP2008524139A (es)
KR (1) KR20070092740A (es)
AR (1) AR055698A1 (es)
AU (1) AU2005315835A1 (es)
BR (1) BRPI0519040A2 (es)
CA (1) CA2590396A1 (es)
CR (1) CR9183A (es)
GT (1) GT200500366A (es)
IL (1) IL183395A0 (es)
MX (1) MX2007007245A (es)
NO (1) NO20073631L (es)
PA (1) PA8656501A1 (es)
PE (1) PE20061157A1 (es)
TW (1) TW200628458A (es)
UY (1) UY29264A1 (es)
WO (1) WO2006063806A1 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005005395A1 (de) * 2005-02-03 2006-08-10 Schering Aktiengesellschaft Thiazolidinone, deren Herstellung und Verwendung als Arzneimittel
EP1989330A4 (en) * 2006-01-31 2009-10-21 Elan Pharm Inc ALPHA-SYNUCLEINE KINASE
EP2247748A2 (en) * 2008-02-13 2010-11-10 Elan Pharma International Limited Alpha-synuclein kinase
EP2141163A1 (de) * 2008-07-02 2010-01-06 Bayer Schering Pharma AG Substituierte Thiazolidinone, deren Herstellung und Verwendung als Arzneimittel
JP5578705B2 (ja) * 2010-03-29 2014-08-27 公益財団法人相模中央化学研究所 （アリール）ジフルオロ酢酸エステル誘導体及びその製造方法
WO2014069434A1 (ja) * 2012-10-30 2014-05-08 カルナバイオサイエンス株式会社 新規チアゾリジノン誘導体
CN105228982B (zh) * 2013-03-20 2018-03-27 拜耳制药股份公司 用于治疗过度增殖性病症的3‑乙酰基氨基‑1‑(苯基‑杂芳基‑氨基羰基或苯基‑杂芳基‑羰基氨基)苯衍生物
US20160052898A1 (en) * 2013-03-20 2016-02-25 Bayer Pharma Aktiengesellschaft Novel compounds
WO2015116696A1 (en) 2014-01-28 2015-08-06 Massachusetts Institute Of Technology Combination therapies and methods of use thereof for treating cancer
TN2016000550A1 (en) * 2014-06-16 2018-04-04 Centre Hospitalier Regional Univ De Lille Chru Compounds, pharmaceutical composition and their use in treating neurodegenerative diseases
EP4479042A1 (en) 2022-02-18 2024-12-25 Massachusetts Institute Of Technology Cancer treatment by combined inhibition of polo-like kinase and microtubule polymerization

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1501794A1 (de) * 2002-05-03 2005-02-02 Schering Aktiengesellschaft Thiazolidinone und ihre verwendung als polo like kinase inhibitoren
DE10351744A1 (de) * 2003-10-31 2005-06-16 Schering Ag Thiazolidinone, deren Herstellung und Verwendung als Arzneimittel

Also Published As

Publication number Publication date
PA8656501A1 (es) 2006-09-08
JP2008524139A (ja) 2008-07-10
IL183395A0 (en) 2007-09-20
BRPI0519040A2 (pt) 2009-01-13
PE20061157A1 (es) 2006-11-16
WO2006063806A1 (de) 2006-06-22
US20100048891A1 (en) 2010-02-25
KR20070092740A (ko) 2007-09-13
NO20073631L (no) 2007-09-12
UY29264A1 (es) 2006-06-30
AR055698A1 (es) 2007-09-05
MX2007007245A (es) 2008-02-25
CA2590396A1 (en) 2006-06-22
US20070015759A1 (en) 2007-01-18
EP1824834A1 (de) 2007-08-29
GT200500366A (es) 2006-12-04
AU2005315835A1 (en) 2006-06-22
TW200628458A (en) 2006-08-16

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal (granting procedure)