CR9578A - Inhibidores de la adenilato ciclasa soluble - Google Patents
Inhibidores de la adenilato ciclasa solubleInfo
- Publication number
- CR9578A CR9578A CR9578A CR9578A CR9578A CR 9578 A CR9578 A CR 9578A CR 9578 A CR9578 A CR 9578A CR 9578 A CR9578 A CR 9578A CR 9578 A CR9578 A CR 9578A
- Authority
- CR
- Costa Rica
- Prior art keywords
- adenylate
- cycling
- inhibitors
- soluble
- medicine
- Prior art date
Links
- UDMBCSSLTHHNCD-KQYNXXCUSA-N adenosine 5'-monophosphate Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O UDMBCSSLTHHNCD-KQYNXXCUSA-N 0.000 title 1
- 230000001351 cycling effect Effects 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/16—Masculine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Furan Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Saccharide Compounds (AREA)
Abstract
La invencion se relaciona con compuestos de la formula general (I), y con su preparacion y su uso como medicamento.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102005027274A DE102005027274A1 (de) | 2005-06-08 | 2005-06-08 | Inhibitoren der löslichen Adenylatzyklase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CR9578A true CR9578A (es) | 2008-03-06 |
Family
ID=37398540
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CR9578A CR9578A (es) | 2005-06-08 | 2007-12-07 | Inhibidores de la adenilato ciclasa soluble |
Country Status (23)
| Country | Link |
|---|---|
| EP (1) | EP1888058B1 (es) |
| JP (1) | JP2008542422A (es) |
| KR (1) | KR20080016617A (es) |
| CN (1) | CN101193631A (es) |
| AR (1) | AR054378A1 (es) |
| AT (1) | ATE431736T1 (es) |
| AU (1) | AU2006256857A1 (es) |
| BR (1) | BRPI0610934A2 (es) |
| CA (1) | CA2606692A1 (es) |
| CR (1) | CR9578A (es) |
| DE (2) | DE102005027274A1 (es) |
| DO (1) | DOP2006000130A (es) |
| EA (1) | EA200702590A1 (es) |
| EC (1) | ECSP078024A (es) |
| GT (1) | GT200600244A (es) |
| IL (1) | IL186914A0 (es) |
| MX (1) | MX2007015493A (es) |
| NO (1) | NO20080104L (es) |
| PE (1) | PE20061488A1 (es) |
| TW (1) | TW200716090A (es) |
| UY (1) | UY29583A1 (es) |
| WO (1) | WO2006131398A2 (es) |
| ZA (1) | ZA200800153B (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102006014319B4 (de) * | 2006-03-23 | 2009-01-08 | Bayer Schering Pharma Aktiengesellschaft | Inhibitoren der löslichen Adenylatzyklase |
| EP2036906A1 (de) * | 2007-09-05 | 2009-03-18 | Bayer Schering Pharma Aktiengesellschaft | Azaindole als Inhibitoren der löslichen Adenylatzyklase |
| MX2024006739A (es) | 2021-12-01 | 2024-06-19 | Pfizer | Derivados de acido 3-fenil-1-benzotiofeno-2-carboxilico como inhibidores de alfa cetoacido deshidrogenasa quinasa de cadena ramificada para el tratamiento de diabetes, enfermedad renal, esteatohepatitis no alcoholica (nash) e insuficiencia cardiaca. |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2635776B1 (fr) * | 1988-09-01 | 1993-06-11 | Rhone Poulenc Agrochimie | Derives amides, procede pour leur fabrication et compositions fongicides les contenant |
| AU2001287060A1 (en) * | 2000-09-05 | 2002-03-22 | University Of Virginia Patent Foundation | Human soluble testicular adenylyl cyclase |
| PL367680A1 (en) * | 2001-06-28 | 2005-03-07 | Pfizer Products Inc. | Triamide-substituted indoles, benzofuranes and benzothiophenes as inhibitors of microsomal triglyceride transfer protein (mtp) and/or apolipoprotein b (apo b) secretion |
| JP3795044B2 (ja) * | 2001-09-14 | 2006-07-12 | メシルジーン、インコーポレイテッド | ヒストンデアセチラーゼの阻害剤 |
| UA79504C2 (en) * | 2002-11-07 | 2007-06-25 | Organon Nv | Indols for treating diseases associated with androgen receptors |
| JP4741491B2 (ja) * | 2003-08-07 | 2011-08-03 | ライジェル ファーマシューティカルズ, インコーポレイテッド | 抗増殖剤としての2,4−ピリミジンジアミン化合物および使用 |
| WO2005034880A2 (en) * | 2003-10-09 | 2005-04-21 | Aton Pharma, Inc. | Thiophene and benzothiophene hydroxamic acid derivatives |
| US9649295B2 (en) * | 2004-01-21 | 2017-05-16 | Cornell Research Foundation, Inc. | Chemical inhibitors of soluble adenylyl cyclase (sAC) |
| WO2005092899A1 (en) * | 2004-03-26 | 2005-10-06 | Methylgene Inc. | Inhibitors of histone deacetylase |
| DE102004047272A1 (de) * | 2004-09-24 | 2006-04-06 | Schering Ag | Inhibitoren der löslichen Adenylatzyklase |
-
2005
- 2005-06-08 DE DE102005027274A patent/DE102005027274A1/de not_active Withdrawn
-
2006
- 2006-06-07 WO PCT/EP2006/005608 patent/WO2006131398A2/en not_active Ceased
- 2006-06-07 EA EA200702590A patent/EA200702590A1/ru unknown
- 2006-06-07 EP EP06762012A patent/EP1888058B1/en not_active Not-in-force
- 2006-06-07 AT AT06762012T patent/ATE431736T1/de not_active IP Right Cessation
- 2006-06-07 DE DE602006006908T patent/DE602006006908D1/de not_active Expired - Fee Related
- 2006-06-07 KR KR1020077028637A patent/KR20080016617A/ko not_active Withdrawn
- 2006-06-07 CN CNA2006800201485A patent/CN101193631A/zh active Pending
- 2006-06-07 MX MX2007015493A patent/MX2007015493A/es not_active Application Discontinuation
- 2006-06-07 GT GT200600244A patent/GT200600244A/es unknown
- 2006-06-07 AR ARP060102365A patent/AR054378A1/es unknown
- 2006-06-07 AU AU2006256857A patent/AU2006256857A1/en not_active Abandoned
- 2006-06-07 UY UY29583A patent/UY29583A1/es not_active Application Discontinuation
- 2006-06-07 BR BRPI0610934-9A patent/BRPI0610934A2/pt not_active IP Right Cessation
- 2006-06-07 PE PE2006000622A patent/PE20061488A1/es not_active Application Discontinuation
- 2006-06-07 JP JP2008515154A patent/JP2008542422A/ja active Pending
- 2006-06-07 CA CA002606692A patent/CA2606692A1/en not_active Abandoned
- 2006-06-08 TW TW095120397A patent/TW200716090A/zh unknown
- 2006-06-08 DO DO2006000130A patent/DOP2006000130A/es unknown
-
2007
- 2007-10-25 IL IL186914A patent/IL186914A0/en unknown
- 2007-12-07 CR CR9578A patent/CR9578A/es not_active Application Discontinuation
- 2007-12-17 EC EC2007008024A patent/ECSP078024A/es unknown
-
2008
- 2008-01-07 NO NO20080104A patent/NO20080104L/no not_active Application Discontinuation
- 2008-01-07 ZA ZA200800153A patent/ZA200800153B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE102005027274A1 (de) | 2006-12-14 |
| EP1888058A2 (en) | 2008-02-20 |
| CN101193631A (zh) | 2008-06-04 |
| ZA200800153B (en) | 2009-03-25 |
| NO20080104L (no) | 2008-03-03 |
| TW200716090A (en) | 2007-05-01 |
| UY29583A1 (es) | 2007-01-31 |
| EA200702590A1 (ru) | 2008-06-30 |
| IL186914A0 (en) | 2008-02-09 |
| ATE431736T1 (de) | 2009-06-15 |
| BRPI0610934A2 (pt) | 2010-08-03 |
| EP1888058B1 (en) | 2009-05-20 |
| AU2006256857A1 (en) | 2006-12-14 |
| ECSP078024A (es) | 2008-01-23 |
| CA2606692A1 (en) | 2006-12-14 |
| PE20061488A1 (es) | 2007-02-03 |
| DE602006006908D1 (de) | 2009-07-02 |
| JP2008542422A (ja) | 2008-11-27 |
| KR20080016617A (ko) | 2008-02-21 |
| GT200600244A (es) | 2007-01-23 |
| WO2006131398A2 (en) | 2006-12-14 |
| DOP2006000130A (es) | 2006-11-30 |
| WO2006131398A3 (en) | 2007-04-19 |
| MX2007015493A (es) | 2008-02-22 |
| AR054378A1 (es) | 2007-06-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal (granting procedure) |