ATE431736T1 - Inhibitoren der löslichen adenylatzyklase - Google Patents

Inhibitoren der löslichen adenylatzyklase

Info

Publication number
ATE431736T1
ATE431736T1 AT06762012T AT06762012T ATE431736T1 AT E431736 T1 ATE431736 T1 AT E431736T1 AT 06762012 T AT06762012 T AT 06762012T AT 06762012 T AT06762012 T AT 06762012T AT E431736 T1 ATE431736 T1 AT E431736T1
Authority
AT
Austria
Prior art keywords
soluble
adenyl cyclase
cyclase inhibitors
inhibitors
adenyl
Prior art date
Application number
AT06762012T
Other languages
English (en)
Inventor
Bernd Buchmann
Duy Nguyen
Martin Fritsch
Bernd Menzenbach
Ulf Boemer
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Application granted granted Critical
Publication of ATE431736T1 publication Critical patent/ATE431736T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D333/70Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16Masculine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Saccharide Compounds (AREA)
AT06762012T 2005-06-08 2006-06-07 Inhibitoren der löslichen adenylatzyklase ATE431736T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005027274A DE102005027274A1 (de) 2005-06-08 2005-06-08 Inhibitoren der löslichen Adenylatzyklase
PCT/EP2006/005608 WO2006131398A2 (en) 2005-06-08 2006-06-07 Inhibitors of soluble adenylate cyclase

Publications (1)

Publication Number Publication Date
ATE431736T1 true ATE431736T1 (de) 2009-06-15

Family

ID=37398540

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06762012T ATE431736T1 (de) 2005-06-08 2006-06-07 Inhibitoren der löslichen adenylatzyklase

Country Status (23)

Country Link
EP (1) EP1888058B1 (de)
JP (1) JP2008542422A (de)
KR (1) KR20080016617A (de)
CN (1) CN101193631A (de)
AR (1) AR054378A1 (de)
AT (1) ATE431736T1 (de)
AU (1) AU2006256857A1 (de)
BR (1) BRPI0610934A2 (de)
CA (1) CA2606692A1 (de)
CR (1) CR9578A (de)
DE (2) DE102005027274A1 (de)
DO (1) DOP2006000130A (de)
EA (1) EA200702590A1 (de)
EC (1) ECSP078024A (de)
GT (1) GT200600244A (de)
IL (1) IL186914A0 (de)
MX (1) MX2007015493A (de)
NO (1) NO20080104L (de)
PE (1) PE20061488A1 (de)
TW (1) TW200716090A (de)
UY (1) UY29583A1 (de)
WO (1) WO2006131398A2 (de)
ZA (1) ZA200800153B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006014319B4 (de) * 2006-03-23 2009-01-08 Bayer Schering Pharma Aktiengesellschaft Inhibitoren der löslichen Adenylatzyklase
EP2036906A1 (de) * 2007-09-05 2009-03-18 Bayer Schering Pharma Aktiengesellschaft Azaindole als Inhibitoren der löslichen Adenylatzyklase
AU2022403203B2 (en) 2021-12-01 2025-09-25 Pfizer Inc. 3-phenyl-1-benzothiophene-2-carboxylic acid derivatives as branched-chain alpha keto acid dehydrogenase kinase inhibitors for the treatment of diabetes, kidney diseases, nash and heart failure

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2635776B1 (fr) * 1988-09-01 1993-06-11 Rhone Poulenc Agrochimie Derives amides, procede pour leur fabrication et compositions fongicides les contenant
WO2002020745A1 (en) * 2000-09-05 2002-03-14 University Of Virginia Patent Foundation Human soluble testicular adenylyl cyclase
CN1880304B (zh) * 2001-06-28 2010-11-24 辉瑞产品公司 三酰胺取代的吲哚、苯并呋喃及苯并噻吩
WO2003024448A2 (en) * 2001-09-14 2003-03-27 Methylgene, Inc. Inhibitors of histone deacetylase
UA79504C2 (en) * 2002-11-07 2007-06-25 Organon Nv Indols for treating diseases associated with androgen receptors
EP1663242B1 (de) * 2003-08-07 2011-04-27 Rigel Pharmaceuticals, Inc. 2,4-pyrimidindiamin-verbindungen und verwendungen als antiproliferative mittel
US7935724B2 (en) * 2003-10-09 2011-05-03 Merck Hdac Research, Llc Thiophene and benzothiophene hydroxamic acid derivatives
EP1706114B1 (de) * 2004-01-21 2012-12-26 Cornell Research Foundation, Inc. Chemische inhibitoren löslicher adenylylcyclase (sac)
EP1735319B1 (de) * 2004-03-26 2017-05-03 MethylGene Inc. Histondeacetylase-hemmer
DE102004047272A1 (de) * 2004-09-24 2006-04-06 Schering Ag Inhibitoren der löslichen Adenylatzyklase

Also Published As

Publication number Publication date
DE602006006908D1 (de) 2009-07-02
DOP2006000130A (es) 2006-11-30
EP1888058B1 (de) 2009-05-20
BRPI0610934A2 (pt) 2010-08-03
DE102005027274A1 (de) 2006-12-14
CR9578A (es) 2008-03-06
KR20080016617A (ko) 2008-02-21
AU2006256857A1 (en) 2006-12-14
ZA200800153B (en) 2009-03-25
NO20080104L (no) 2008-03-03
EP1888058A2 (de) 2008-02-20
CN101193631A (zh) 2008-06-04
JP2008542422A (ja) 2008-11-27
IL186914A0 (en) 2008-02-09
EA200702590A1 (ru) 2008-06-30
AR054378A1 (es) 2007-06-20
UY29583A1 (es) 2007-01-31
TW200716090A (en) 2007-05-01
GT200600244A (es) 2007-01-23
WO2006131398A2 (en) 2006-12-14
PE20061488A1 (es) 2007-02-03
MX2007015493A (es) 2008-02-22
ECSP078024A (es) 2008-01-23
WO2006131398A3 (en) 2007-04-19
CA2606692A1 (en) 2006-12-14

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Legal Events

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