CR9599A - Proteinas de union a il-12/p40 - Google Patents

Proteinas de union a il-12/p40

Info

Publication number
CR9599A
CR9599A CR9599A CR9599A CR9599A CR 9599 A CR9599 A CR 9599A CR 9599 A CR9599 A CR 9599A CR 9599 A CR9599 A CR 9599A CR 9599 A CR9599 A CR 9599A
Authority
CR
Costa Rica
Prior art keywords
proteins
union
antibodies
hil
human
Prior art date
Application number
CR9599A
Other languages
English (en)
Inventor
Susan E Lacy
Emma Fung
Jonathan P Belk
Richard W Dixon
Michael Roguska
Paul R Hinton
Shankar Kumar
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of CR9599A publication Critical patent/CR9599A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6869—Interleukin
    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567—Framework region [FR]
    • C—CHEMISTRY; METALLURGY
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Pulmonology (AREA)
  • Psychiatry (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Pain & Pain Management (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)

Abstract

Proteinas de union a IL-12p40, en particular anticuerpos que se unen a la interleuquina-12 humana (hIL-12) y/o IL-23 humana (hIL-23). Especificamente, ia invencion se relaciona con anticuerpos que son quimericos, con injertos de CDR y anticuerpos humanizados.
CR9599A 2005-06-30 2007-12-18 Proteinas de union a il-12/p40 CR9599A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US69567905P 2005-06-30 2005-06-30

Publications (1)

Publication Number Publication Date
CR9599A true CR9599A (es) 2009-06-05

Family

ID=37605037

Family Applications (10)

Application Number Title Priority Date Filing Date
CR9599A CR9599A (es) 2005-06-30 2007-12-18 Proteinas de union a il-12/p40
CR20130156A CR20130156A (es) 2005-06-30 2013-04-03 Proteínas de la unión a il-12/p40 (divisional 9599)
CR20130153A CR20130153A (es) 2005-06-30 2013-04-03 PROTEÍNAS DE LA UNIÓN A IL-12/P40 (Divisional 9599)
CR20130154A CR20130154A (es) 2005-06-30 2013-04-03 Proteínas de la unión a il-12/p40 (divisional exp. 9599)
CR20130157A CR20130157A (es) 2005-06-30 2013-04-03 PROTEÍNAS DE LA UNIÓN A IL-12/P40 (Divisional 9599)
CR20130155A CR20130155A (es) 2005-06-30 2013-04-03 PROTEÍNAS DE LA UNIÓN A IL-12/P40 (Divisional 9599)
CR20130151A CR20130151A (es) 2005-06-30 2013-04-03 PROTEÍNAS DE LA UNIÓN A IL-12/P40 (Divisional 9599)
CR20130149A CR20130149A (es) 2005-06-30 2013-04-03 Proteínas de la unión a il-12/p40 (divisional 9599)
CR20130152A CR20130152A (es) 2005-06-30 2013-04-03 Proteínas de la unión a il-12/p40 (divisional 9599)
CR20130150A CR20130150A (es) 2005-06-30 2013-04-03 Proteínas de la unión a il-12/p40 (divisional exp. 9599)

Family Applications After (9)

Application Number Title Priority Date Filing Date
CR20130156A CR20130156A (es) 2005-06-30 2013-04-03 Proteínas de la unión a il-12/p40 (divisional 9599)
CR20130153A CR20130153A (es) 2005-06-30 2013-04-03 PROTEÍNAS DE LA UNIÓN A IL-12/P40 (Divisional 9599)
CR20130154A CR20130154A (es) 2005-06-30 2013-04-03 Proteínas de la unión a il-12/p40 (divisional exp. 9599)
CR20130157A CR20130157A (es) 2005-06-30 2013-04-03 PROTEÍNAS DE LA UNIÓN A IL-12/P40 (Divisional 9599)
CR20130155A CR20130155A (es) 2005-06-30 2013-04-03 PROTEÍNAS DE LA UNIÓN A IL-12/P40 (Divisional 9599)
CR20130151A CR20130151A (es) 2005-06-30 2013-04-03 PROTEÍNAS DE LA UNIÓN A IL-12/P40 (Divisional 9599)
CR20130149A CR20130149A (es) 2005-06-30 2013-04-03 Proteínas de la unión a il-12/p40 (divisional 9599)
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