CR9930A - Compuestos - Google Patents

Compuestos

Info

Publication number
CR9930A
CR9930A CR9930A CR9930A CR9930A CR 9930 A CR9930 A CR 9930A CR 9930 A CR9930 A CR 9930A CR 9930 A CR9930 A CR 9930A CR 9930 A CR9930 A CR 9930A
Authority
CR
Costa Rica
Prior art keywords
compounds
antibacterials
compounds containing
containing tricyclic
tricyclic nitrogen
Prior art date
Application number
CR9930A
Other languages
English (en)
Inventor
Nathalie Cailleau
David Thomas Davies
Joel Michael Esken
Alan Joseph Hennessy
Sukumar Senthil Kumar Kusalakumari
Roger Edward Markwell
Timothy James Miles
Neil David Pearson
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of CR9930A publication Critical patent/CR9930A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Compuestos que contienen nitrogeno triciclico y sus usos como antibacterianos.
CR9930A 2005-10-21 2008-04-25 Compuestos CR9930A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72897505P 2005-10-21 2005-10-21
US82659006P 2006-09-22 2006-09-22

Publications (1)

Publication Number Publication Date
CR9930A true CR9930A (es) 2008-07-29

Family

ID=38256822

Family Applications (1)

Application Number Title Priority Date Filing Date
CR9930A CR9930A (es) 2005-10-21 2008-04-25 Compuestos

Country Status (26)

Country Link
US (2) US20080221110A1 (es)
EP (1) EP1954697B1 (es)
JP (1) JP2009512695A (es)
KR (1) KR20080064173A (es)
AR (1) AR057981A1 (es)
AT (1) ATE458737T1 (es)
AU (1) AU2006335042A1 (es)
BR (1) BRPI0617467A2 (es)
CA (1) CA2626641A1 (es)
CR (1) CR9930A (es)
CY (1) CY1110137T1 (es)
DE (1) DE602006012535D1 (es)
DK (1) DK1954697T3 (es)
EA (1) EA200801128A1 (es)
ES (1) ES2340531T3 (es)
HR (1) HRP20100194T8 (es)
IL (1) IL190803A0 (es)
MA (1) MA29873B1 (es)
NO (1) NO20082191L (es)
NZ (1) NZ567315A (es)
PE (1) PE20070793A1 (es)
PL (1) PL1954697T3 (es)
PT (1) PT1954697E (es)
SI (1) SI1954697T1 (es)
TW (1) TW200736263A (es)
WO (1) WO2007081597A2 (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2340531T3 (es) * 2005-10-21 2010-06-04 Glaxo Group Limited Compuestos triciclos peri-condensados utiles como agentes antibacterianos.
ATE465163T1 (de) * 2005-12-22 2010-05-15 Glaxo Group Ltd Heterocyclische verbindungen, ihre herstellung und ihre verwendung als antibakterielle mittel
EP2001887B1 (en) 2006-04-06 2010-09-15 Glaxo Group Limited Pyrrolo-quinoxalinone derivatives as antibacterials
GB0608263D0 (en) 2006-04-26 2006-06-07 Glaxo Group Ltd Compounds
GB0613208D0 (en) * 2006-07-03 2006-08-09 Glaxo Group Ltd Compounds
GB0705672D0 (en) * 2007-03-23 2007-05-02 Glaxo Group Ltd Compounds
CL2008001002A1 (es) 2007-04-11 2008-10-17 Actelion Pharmaceuticals Ltd Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana.
AU2008240764C1 (en) 2007-04-20 2011-10-20 Glaxo Group Limited Tricyclic nitrogen containing compounds as antibacterial agents
GB0707706D0 (en) * 2007-04-20 2007-05-30 Glaxo Group Ltd Compounds
EP2005995A1 (en) * 2007-06-22 2008-12-24 Glaxo Group Limited Heterocyclic compounds for the treatment of tuberculosis
EP2080761A1 (en) 2008-01-18 2009-07-22 Glaxo Group Limited Compounds
ES2411930T3 (es) 2008-02-20 2013-07-09 Actelion Pharmaceuticals Ltd. Compuestos antibióticos azatricíclicos
TW200944529A (en) 2008-04-15 2009-11-01 Actelion Pharmaceuticals Ltd Tricyclic antibiotics
CN102105467A (zh) 2008-08-04 2011-06-22 埃科特莱茵药品有限公司 三环烷氨基甲基噁唑烷酮衍生物
DK2344495T3 (en) * 2008-10-07 2015-02-02 Actelion Pharmaceuticals Ltd TRICYCLIC OXAZOLIDINON ANTIBIOTIC COMPOUNDS
EP2352734A1 (en) 2008-10-17 2011-08-10 Glaxo Group Limited Tricyclic nitrogen compounds used as antibacterials
AU2009325902B2 (en) 2008-12-12 2015-01-29 Idorsia Pharmaceuticals Ltd 5-amino-2-(1-hydroxy-ethyl)-tetrahydropyran derivatives
US8318940B2 (en) 2009-01-15 2012-11-27 Glaxo Group Limited Naphthyridin-2 (1 H)-one compounds useful as antibacterials
AR087875A1 (es) 2011-09-16 2014-04-23 Actelion Pharmaceuticals Ltd Proceso para la elaboracion de derivados de piridazina como intermediarios de sintesis de antibioticos
TW201326180A (zh) 2011-11-30 2013-07-01 Actelion Pharmaceuticals Ltd ３，７－二取代八氫－２Ｈ－吡啶并［４，３－ｅ］［１，３］□嗪－２－酮抗生素
US10702521B2 (en) 2014-08-22 2020-07-07 Glaxosmithkline Intellectual Property Development Limited Methods for treating neisseria gonorrhoeae infection with substituted 1,2-dihydro-2A,5,8A-triazaacenaphthylene-3,8-diones
US11185076B2 (en) 2017-02-28 2021-11-30 Mitsui Chemicals Agro, Inc. Composition for controlling plant diseases and method for controlling plant diseases applying the same
EP3621649A2 (en) * 2017-05-10 2020-03-18 Albajuna Therapeutics, S.L. Fc-fusion protein derivatives with high dual hiv antiviral and immunomodulatory activity
CN115151540A (zh) 2019-12-02 2022-10-04 风暴治疗有限公司 作为mettl3抑制剂的多杂环化合物
BR112022010924A2 (pt) 2019-12-06 2022-09-06 Vertex Pharma Tetra-hidrofuranos substituídos como moduladores de canais de sódio
SMT202500481T1 (it) 2021-06-04 2026-01-12 Vertex Pharma N-(idrossialchil(etero)aril)tetraidrofuran carbossammidi come modulatori di canali del sodio

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3323868A (en) * 1961-12-14 1967-06-06 Laporte Chemical Manufacture of hydrogen peroxide
NL294427A (es) * 1962-06-23
GB1394373A (en) * 1972-05-17 1975-05-14 Pfizer Ltd Control of plant diseases
US4066706A (en) * 1975-04-21 1978-01-03 Halcon International, Inc. Preparation of ethylbenzene hydroperoxide
DE2805915C3 (de) * 1978-02-13 1981-11-05 Dynamit Nobel Ag, 5210 Troisdorf Reaktor zur Oxidation von Gemischen aus p-Xylol und p-Toluylsäuremethylester mit sauerstoffhaltigen Gasen in flüssiger Phase
DE2914218C2 (de) * 1978-04-12 1985-10-24 Otsuka Pharmaceutical Co. Ltd., Tokio/Tokyo N-Acylderivate des Ampicillins und Amoxicillins, Verfahren zu deren Herstellung und pharmazeutische Zubereitungen, welche die Verbindungen enthalten
US4416884A (en) * 1978-04-12 1983-11-22 Otsuka Pharmaceutical Co., Ltd. Piperazinylbenzoheterocyclic compounds
NO156828C (no) * 1980-11-10 1987-12-02 Otsuka Pharma Co Ltd Analogifremgangsm te for fremstilling av antibakterielt virksomme benzoheterocykliske forbindelser.
EP0090769B1 (de) * 1982-03-25 1986-08-20 Ciba-Geigy Ag Verfahren zur Herstellung von 1,2,5,6-Tetrahydro-4H-pyrrolo(3,2,1-ij)-chinolin-4-on und neue 5-Halogen-1,2,3-(1,2-dihydropyrrolo)-4-chinolone als Zwischenprodukte zur Durchführung des Verfahrens
US4595755A (en) * 1982-03-25 1986-06-17 Ciba-Geigy Corporation 5-halo-1,2,3-(1,2-dihydropyrrolo)-4-quinolones
US4603199A (en) * 1982-10-25 1986-07-29 Riker Laboratories, Inc. Phenyl-substituted tricyclic antibacterial agent intermediates
US4443447A (en) * 1982-10-25 1984-04-17 Riker Laboratories, Inc. Phenyl-substituted tricyclic antibacterial agents
US6121285A (en) * 1995-11-22 2000-09-19 Daiichi Pharmaceutical Co., Ltd. Substituted aminocycloalkylpyrrolidine derivatives and cis-substituted aminocycloalkylpyrrolidine derivatives
GB9622386D0 (en) * 1996-10-28 1997-01-08 Sandoz Ltd Organic compounds
JPH11222407A (ja) * 1997-11-14 1999-08-17 Sankyo Co Ltd 新規殺菌剤
US6689765B2 (en) * 1999-05-04 2004-02-10 Schering Corporation Piperazine derivatives useful as CCR5 antagonists
US7825121B2 (en) * 1999-05-04 2010-11-02 Schering Corporation Piperazine derivatives useful as CCR5 antagonists
US6289745B1 (en) * 1999-05-04 2001-09-18 James Bowers High temperature insertion type flow element and mounting extension
US6391865B1 (en) * 1999-05-04 2002-05-21 Schering Corporation Piperazine derivatives useful as CCR5 antagonists
GB0101577D0 (en) * 2001-01-22 2001-03-07 Smithkline Beecham Plc Compounds
AR032920A1 (es) * 2001-03-01 2003-12-03 Smithkline Beecham Corp Compuestos inhibidores de las peptido-deformilasas y medios para tratar infecciones bacterianas utilizando dichos inhibidores
GB0112836D0 (en) * 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
EP1470131A2 (en) * 2002-01-29 2004-10-27 Glaxo Group Limited Aminopiperidine compounds, process for their preparation, and pharmaceutical compositions containing them
AR040336A1 (es) * 2002-06-26 2005-03-30 Glaxo Group Ltd Compuesto de piperidina, uso del mismo para la fabricacion de un medicamento, composicion farmaceutica que lo comprende y procedimiento para preparar dicho compuesto
US7196090B2 (en) * 2002-07-25 2007-03-27 Warner-Lambert Company Kinase inhibitors
AR042486A1 (es) * 2002-12-18 2005-06-22 Glaxo Group Ltd Compuesto de quinolina y naftiridina halosustituido en la posicion 3, procedimiento para preparar el compuesto, composicion farmaceutica que lo comprende y su uso para preparar dicha composicion .
WO2005033108A1 (en) * 2003-09-22 2005-04-14 Janssen Pharmaceutica, N.V. 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones
WO2006002047A2 (en) * 2004-06-15 2006-01-05 Glaxo Group Limited Antibacterial agents
JP2008505920A (ja) * 2004-07-08 2008-02-28 グラクソ　グループ　リミテッド 抗菌剤
US7732612B2 (en) * 2004-09-09 2010-06-08 Janssen Pharmaceutica, N.V. 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones
MY150958A (en) * 2005-06-16 2014-03-31 Astrazeneca Ab Compounds for the treatment of multi-drug resistant bacterial infections
EP1900732A4 (en) * 2005-06-24 2009-11-18 Toyama Chemical Co Ltd NEW NITROGENATED HETEROCYCLIC COMPOUND AND SALT THEREOF
DE102005050892A1 (de) * 2005-10-21 2007-04-26 Boehringer Ingelheim Pharma Gmbh & Co. Kg Ausgewählte CGRP-Antagonisten, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel
ES2340531T3 (es) * 2005-10-21 2010-06-04 Glaxo Group Limited Compuestos triciclos peri-condensados utiles como agentes antibacterianos.
GB0521563D0 (en) * 2005-10-21 2005-11-30 Glaxo Group Ltd Novel compounds
ATE465163T1 (de) * 2005-12-22 2010-05-15 Glaxo Group Ltd Heterocyclische verbindungen, ihre herstellung und ihre verwendung als antibakterielle mittel
EP2001887B1 (en) * 2006-04-06 2010-09-15 Glaxo Group Limited Pyrrolo-quinoxalinone derivatives as antibacterials
GB0608263D0 (en) * 2006-04-26 2006-06-07 Glaxo Group Ltd Compounds
AU2007268749B2 (en) * 2006-05-26 2012-07-26 Taisho Pharmaceutical Co., Ltd. Novel heterocyclic compound or salt thereof and intermediate thereof
GB0613208D0 (en) * 2006-07-03 2006-08-09 Glaxo Group Ltd Compounds
EP1992628A1 (en) * 2007-05-18 2008-11-19 Glaxo Group Limited Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones
GB0705672D0 (en) * 2007-03-23 2007-05-02 Glaxo Group Ltd Compounds
EP1980251A1 (en) * 2007-04-13 2008-10-15 Glaxo Group Limited Pyrrolo[3,2,1-ij]quinoline-4-one derivatives for treating tuberculosis
GB0707708D0 (en) * 2007-04-20 2007-05-30 Glaxo Group Ltd Compounds
GB0707706D0 (en) * 2007-04-20 2007-05-30 Glaxo Group Ltd Compounds
AU2008240764C1 (en) * 2007-04-20 2011-10-20 Glaxo Group Limited Tricyclic nitrogen containing compounds as antibacterial agents

Also Published As

Publication number Publication date
HRP20100194T1 (hr) 2010-05-31
KR20080064173A (ko) 2008-07-08
PE20070793A1 (es) 2007-08-23
TW200736263A (en) 2007-10-01
SI1954697T1 (sl) 2010-05-31
JP2009512695A (ja) 2009-03-26
AR057981A1 (es) 2008-01-09
PT1954697E (pt) 2010-05-17
ES2340531T3 (es) 2010-06-04
EP1954697B1 (en) 2010-02-24
NO20082191L (no) 2008-07-16
CY1110137T1 (el) 2015-01-14
US20080221110A1 (en) 2008-09-11
EA200801128A1 (ru) 2008-10-30
PL1954697T3 (pl) 2010-07-30
BRPI0617467A2 (pt) 2011-07-26
WO2007081597A2 (en) 2007-07-19
HRP20100194T8 (hr) 2010-06-30
IL190803A0 (en) 2008-12-29
ATE458737T1 (de) 2010-03-15
CA2626641A1 (en) 2007-07-19
NZ567315A (en) 2011-01-28
DK1954697T3 (da) 2010-06-14
EP1954697A2 (en) 2008-08-13
HK1118546A1 (en) 2009-02-13
DE602006012535D1 (de) 2010-04-08
WO2007081597A3 (en) 2008-06-12
AU2006335042A1 (en) 2007-07-19
MA29873B1 (fr) 2008-10-03
US20080280892A1 (en) 2008-11-13

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal (granting procedure)