CS212304B2 - Method of making the salts of the 6,7-dihalogen-3,4-dihydro-3-oxo-chinxalin-carboxyl acids with defended amines - Google Patents

Method of making the salts of the 6,7-dihalogen-3,4-dihydro-3-oxo-chinxalin-carboxyl acids with defended amines Download PDF

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Publication number
CS212304B2
CS212304B2 CS807188A CS718880A CS212304B2 CS 212304 B2 CS212304 B2 CS 212304B2 CS 807188 A CS807188 A CS 807188A CS 718880 A CS718880 A CS 718880A CS 212304 B2 CS212304 B2 CS 212304B2
Authority
CS
Czechoslovakia
Prior art keywords
oxo
dihydro
carboxylic acid
salt
quinoxaline carboxylic
Prior art date
Application number
CS807188A
Other languages
Czech (cs)
English (en)
Inventor
Riaz F Abdulla
Donald C Delong
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of CS212304B2 publication Critical patent/CS212304B2/cs

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40Benzopyrazines
    • C07D241/44Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/07Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms
    • C07C205/11Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to carbon atoms of six-membered aromatic rings
    • C07C205/12Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to carbon atoms of six-membered aromatic rings the six-membered aromatic ring or a condensed ring system containing that ring being substituted by halogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/33Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C211/39Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton
    • C07C211/41Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing condensed ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/96Spiro-condensed ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/18Systems containing only non-condensed rings with a ring being at least seven-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/36Systems containing two condensed rings the rings having more than two atoms in common
    • C07C2602/42Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing seven carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/56Ring systems containing bridged rings
    • C07C2603/58Ring systems containing bridged rings containing three rings
    • C07C2603/70Ring systems containing bridged rings containing three rings containing only six-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/56Ring systems containing bridged rings
    • C07C2603/58Ring systems containing bridged rings containing three rings
    • C07C2603/70Ring systems containing bridged rings containing three rings containing only six-membered rings
    • C07C2603/74Adamantanes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/56Ring systems containing bridged rings
    • C07C2603/58Ring systems containing bridged rings containing three rings
    • C07C2603/76Ring systems containing bridged rings containing three rings containing at least one ring with more than six ring members

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CS807188A 1979-10-25 1980-10-23 Method of making the salts of the 6,7-dihalogen-3,4-dihydro-3-oxo-chinxalin-carboxyl acids with defended amines CS212304B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/088,275 US4252954A (en) 1979-10-25 1979-10-25 Salts of dihalo-3,4-dihydro-3-oxo-2-quinoxaline carboxylic acids and hindered amines

Publications (1)

Publication Number Publication Date
CS212304B2 true CS212304B2 (en) 1982-03-26

Family

ID=22210429

Family Applications (1)

Application Number Title Priority Date Filing Date
CS807188A CS212304B2 (en) 1979-10-25 1980-10-23 Method of making the salts of the 6,7-dihalogen-3,4-dihydro-3-oxo-chinxalin-carboxyl acids with defended amines

Country Status (20)

Country Link
US (1) US4252954A (fr)
EP (1) EP0029658A1 (fr)
JP (1) JPS5681569A (fr)
AU (1) AU6351280A (fr)
BE (1) BE885793A (fr)
CA (1) CA1149381A (fr)
CS (1) CS212304B2 (fr)
DD (1) DD153689A5 (fr)
DK (1) DK449780A (fr)
ES (1) ES496210A0 (fr)
FI (1) FI803294L (fr)
FR (1) FR2467848A1 (fr)
GB (1) GB2061936A (fr)
GR (1) GR69994B (fr)
IL (1) IL61313A0 (fr)
IT (1) IT1134009B (fr)
PL (1) PL227421A1 (fr)
PT (1) PT71939B (fr)
YU (1) YU268880A (fr)
ZA (1) ZA806437B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD281614A5 (de) * 1988-09-02 1990-08-15 Univ Berlin Humboldt Verfahren zur herstellung von virostatisch wirksamendiazinsubstituierten 1-adamantanen
AU9049391A (en) * 1990-12-20 1992-07-22 Warner-Lambert Company 2-acylamido derivatives of 3,4-dihydro-3-oxo-quinoxaline having pharmaceutical activity
US6348461B1 (en) * 1997-09-01 2002-02-19 Kyorin Pharmaceutical Co., Ltd. 6,7-asymmetrically disubstituted quinoxalinecarboxylic acid derivatives, addition salts thereof, and processes for the preparation of both
US20050026844A1 (en) * 2003-04-03 2005-02-03 Regents Of The University Of California Inhibitors for the soluble epoxide hydrolase
WO2005089380A2 (fr) 2004-03-16 2005-09-29 The Regents Of The University Of California Reduction de la nephropathie au moyen d'inhibiteurs d'hydrolase d'epoxyde soluble et d'epoxyeicosanoides
JP2008517072A (ja) * 2004-10-20 2008-05-22 ザ レジェンツ オブ ザ ユニバーシティー オブ カリフォルニア 可溶性エポキシド加水分解酵素の改良された阻害剤
AR059826A1 (es) * 2006-03-13 2008-04-30 Univ California Inhibidores de urea conformacionalmente restringidos de epoxido hidrolasa soluble
WO2012054093A2 (fr) 2010-01-29 2012-04-26 The Regents Of The University Of California Inhibiteurs d'acyl pipéridine d'époxyde hydrolase soluble
US20130338061A1 (en) * 2010-10-08 2013-12-19 Lipa Shah Salts and Polymorphs of Sulfamide NS3 Inhibitors
JP6406159B2 (ja) 2015-08-04 2018-10-17 株式会社デンソー 車載表示制御装置、車載表示制御方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3355355A (en) * 1965-02-05 1967-11-28 Smith Kline French Lab Antiviral cycloalkylamine compositions and method
DE1770697C3 (de) * 1967-07-06 1981-04-23 Dupher International Research B.V., Weesp 2,2-(N-Methyl-2-azatetramethylen)- -adamantan, dessen Salze, Verfahren zu deren Herstellung und Arzneimittel
GB1438349A (en) * 1973-09-13 1976-06-03 Post Office Conductor assemblies for cables
US4181724A (en) * 1978-09-11 1980-01-01 The Upjohn Company Quinoxalinone compounds useful for expanding the lumina or air passages in mammals
PH15791A (en) * 1978-10-20 1983-03-25 Lilly Co Eli Pharmaceutical composition containing 3,4-dihydro-3-oxoquinoxalines

Also Published As

Publication number Publication date
CA1149381A (fr) 1983-07-05
AU6351280A (en) 1981-04-30
IT8025538A0 (it) 1980-10-23
PL227421A1 (fr) 1981-06-19
US4252954A (en) 1981-02-24
IL61313A0 (en) 1980-12-31
PT71939A (en) 1980-11-01
FI803294A7 (fi) 1981-04-26
FI803294L (fi) 1981-04-26
DK449780A (da) 1981-04-26
ZA806437B (en) 1982-05-26
YU268880A (en) 1983-02-28
GB2061936A (en) 1981-05-20
FR2467848A1 (fr) 1981-04-30
ES8205207A1 (es) 1981-10-01
PT71939B (en) 1981-08-31
EP0029658A1 (fr) 1981-06-03
ES496210A0 (es) 1981-10-01
BE885793A (fr) 1981-04-21
IT1134009B (it) 1986-07-24
JPS5681569A (en) 1981-07-03
GR69994B (fr) 1982-07-23
DD153689A5 (de) 1982-01-27

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