CS235524B2 - Method of levonantradole derivatives solubilization - Google Patents

Method of levonantradole derivatives solubilization Download PDF

Info

Publication number
CS235524B2
CS235524B2 CS82174A CS17482A CS235524B2 CS 235524 B2 CS235524 B2 CS 235524B2 CS 82174 A CS82174 A CS 82174A CS 17482 A CS17482 A CS 17482A CS 235524 B2 CS235524 B2 CS 235524B2
Authority
CS
Czechoslovakia
Prior art keywords
concentration
sodium
levonantradol
solution
added
Prior art date
Application number
CS82174A
Other languages
Czech (cs)
English (en)
Inventor
Armando J Agniar
Bijan Rasadi
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of CS235524B2 publication Critical patent/CS235524B2/cs

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Neurology (AREA)
  • Otolaryngology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CS82174A 1981-01-09 1982-01-08 Method of levonantradole derivatives solubilization CS235524B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/223,672 US4406888A (en) 1981-01-09 1981-01-09 Aqueous micellar solutions of levonantradol and N-methyllevonantradol and lyophilic forms thereof for reconstitution

Publications (1)

Publication Number Publication Date
CS235524B2 true CS235524B2 (en) 1985-05-15

Family

ID=22837540

Family Applications (1)

Application Number Title Priority Date Filing Date
CS82174A CS235524B2 (en) 1981-01-09 1982-01-08 Method of levonantradole derivatives solubilization

Country Status (17)

Country Link
US (1) US4406888A (de)
EP (1) EP0056681A3 (de)
JP (1) JPS57136512A (de)
AU (1) AU528316B2 (de)
CA (1) CA1172569A (de)
CS (1) CS235524B2 (de)
DK (1) DK4382A (de)
ES (1) ES8304429A1 (de)
FI (1) FI813969A7 (de)
GR (1) GR76514B (de)
HU (1) HU186462B (de)
IL (1) IL64731A0 (de)
NO (1) NO820045L (de)
NZ (1) NZ199415A (de)
PH (1) PH17593A (de)
PT (1) PT74257B (de)
ZA (1) ZA82118B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE33239E (en) * 1983-09-06 1990-06-26 Farmaceutisk Laboratorium Ferring A/S Packaged stable enema solution or suspension containing 5-aminosalicyclic acid
US4657900A (en) * 1983-09-27 1987-04-14 Rowell Laboratories Pharmaceutical article of manufacture comprising a bisulfite stabilized aqueous solution of 5-aminosalicylic acid and method
GB9512854D0 (en) * 1995-06-23 1995-08-23 Wellcome Found Novel formulation
RU2117481C1 (ru) * 1997-07-15 1998-08-20 Государственный научно-исследовательский институт органической химии и технологии Анальгетическое средство и способ его приготовления
US8163797B2 (en) * 2003-12-31 2012-04-24 Actavis Elizabeth Llc Method of treating with stable pravastatin formulation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2391552A (en) * 1942-02-25 1945-12-25 Curtis David Stabilized aromatic compounds
BE786427A (fr) * 1971-07-19 1973-01-18 Pfizer Compositions aqueuses de doxycycline
SE7704749L (sv) * 1976-05-17 1977-12-05 Pfizer Kinoliner och forfarande och mellanprodukter for framstellning derav
BE854655A (fr) 1976-05-17 1977-11-16 Pfizer 9-hydroxyhexahydrobenzo (c) quinoleines et intermediaires de synthese
US4260764A (en) * 1976-12-22 1981-04-07 Pfizer Inc. 9-Hydroxyoctahydrobenzo [C] quinolines and intermediates therefor
US4320124A (en) * 1980-10-17 1982-03-16 Pfizer Inc. Composition for enhancing binding of a benzodiazepine to central benzodiazepine receptors and use thereof

Also Published As

Publication number Publication date
EP0056681A2 (de) 1982-07-28
ES508609A0 (es) 1983-03-01
FI813969L (fi) 1982-07-10
DK4382A (da) 1982-07-10
HU186462B (en) 1985-08-28
ZA82118B (en) 1982-11-24
PT74257B (en) 1984-05-29
AU7940482A (en) 1982-07-22
CA1172569A (en) 1984-08-14
US4406888A (en) 1983-09-27
AU528316B2 (en) 1983-04-21
EP0056681A3 (de) 1983-07-20
IL64731A0 (en) 1982-03-31
NZ199415A (en) 1985-04-30
ES8304429A1 (es) 1983-03-01
JPS57136512A (en) 1982-08-23
FI813969A7 (fi) 1982-07-10
PH17593A (en) 1984-10-02
NO820045L (no) 1982-07-12
PT74257A (en) 1982-02-01
GR76514B (de) 1984-08-10

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