CU20140082A7 - Pirimidinas y triazinas fusionadas sustituidas y sus uso - Google Patents

Pirimidinas y triazinas fusionadas sustituidas y sus uso

Info

Publication number
CU20140082A7
CU20140082A7 CU2014000082A CU20140082A CU20140082A7 CU 20140082 A7 CU20140082 A7 CU 20140082A7 CU 2014000082 A CU2014000082 A CU 2014000082A CU 20140082 A CU20140082 A CU 20140082A CU 20140082 A7 CU20140082 A7 CU 20140082A7
Authority
CU
Cuba
Prior art keywords
pyrimidines
fusionated
triazins
replaced
prevention
Prior art date
Application number
CU2014000082A
Other languages
English (en)
Inventor
Markus Follmann
Johannes-Peter Stach
Gorden Redlich
Nils Griebenow
Dieter Lang
Frank Wunder
Walter Hübsch
Adrian Tersteegen
Alexandros Vakalopoulos
Original Assignee
Bayer Ip Gmbh
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47559479&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CU20140082(A7) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Ip Gmbh, Bayer Pharma AG filed Critical Bayer Ip Gmbh
Publication of CU20140082A7 publication Critical patent/CU20140082A7/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente solicitud se refiere a pirimidinas y triazinas condensadas sustituidas, a procesos para su preparación, a su uso solas o en combinaciones para el tratamiento y/o la prevención de enfermedades, y a su uso para producir medicamentos para el tratamiento y/o la prevención de enfermedades, en concreto para el tratamiento y/o la prevención de trastornos cardiovasculares.
CU2014000082A 2012-01-11 2014-07-07 Pirimidinas y triazinas fusionadas sustituidas y sus uso CU20140082A7 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102012200349A DE102012200349A1 (de) 2012-01-11 2012-01-11 Substituierte annellierte Pyrimidine und Triazine und ihre Verwendung
PCT/EP2013/050381 WO2013104703A1 (de) 2012-01-11 2013-01-10 Substituierte annellierte pyrimidine und triazine und ihre verwendung

Publications (1)

Publication Number Publication Date
CU20140082A7 true CU20140082A7 (es) 2014-10-30

Family

ID=47559479

Family Applications (1)

Application Number Title Priority Date Filing Date
CU2014000082A CU20140082A7 (es) 2012-01-11 2014-07-07 Pirimidinas y triazinas fusionadas sustituidas y sus uso

Country Status (29)

Country Link
US (2) US20140357637A1 (es)
EP (1) EP2802592A1 (es)
JP (1) JP6251183B2 (es)
KR (1) KR20140114416A (es)
CN (1) CN104812762B (es)
AP (1) AP2014007844A0 (es)
AU (1) AU2013208968A1 (es)
BR (1) BR112014016971A8 (es)
CA (1) CA2860855A1 (es)
CL (1) CL2014001779A1 (es)
CO (1) CO7000776A2 (es)
CR (1) CR20140327A (es)
CU (1) CU20140082A7 (es)
DE (1) DE102012200349A1 (es)
DO (1) DOP2014000160A (es)
EA (1) EA025837B1 (es)
EC (1) ECSP14008556A (es)
GT (1) GT201400147A (es)
HK (1) HK1211585A1 (es)
IL (1) IL233460A0 (es)
MA (1) MA35844B1 (es)
MX (1) MX2014008201A (es)
NZ (1) NZ626394A (es)
PE (1) PE20142293A1 (es)
PH (1) PH12014501595A1 (es)
SG (2) SG11201403345UA (es)
TN (1) TN2014000298A1 (es)
WO (1) WO2013104703A1 (es)
ZA (1) ZA201405042B (es)

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JP6849618B2 (ja) 2015-07-23 2021-03-24 バイエル・ファルマ・アクティエンゲゼルシャフト 中性エンドペプチダーゼの阻害剤（ＮＥＰ阻害剤）および／またはアンジオテンシンＩＩ拮抗薬と組み合わせた可溶性グアニル酸シクラーゼ（ｓＧＣ）の刺激薬および／または活性化薬ならびにその使用
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MA35844B1 (fr) 2014-12-01
EP2802592A1 (de) 2014-11-19
MX2014008201A (es) 2014-08-08
US20140357637A1 (en) 2014-12-04
SG11201403345UA (en) 2014-09-26
AP2014007844A0 (en) 2014-07-31
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JP2015503605A (ja) 2015-02-02
DOP2014000160A (es) 2014-08-31
CN104812762B (zh) 2018-01-16
AU2013208968A1 (en) 2014-07-24
WO2013104703A1 (de) 2013-07-18
GT201400147A (es) 2015-04-06
BR112014016971A8 (pt) 2017-07-04
PE20142293A1 (es) 2014-12-19
CA2860855A1 (en) 2013-07-18
CO7000776A2 (es) 2014-07-21
US9505786B2 (en) 2016-11-29
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US20150274754A1 (en) 2015-10-01
HK1211585A1 (en) 2016-05-27
CR20140327A (es) 2014-11-26
DE102012200349A1 (de) 2013-07-11
ZA201405042B (en) 2016-08-31
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JP6251183B2 (ja) 2017-12-20
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IL233460A0 (en) 2014-08-31
BR112014016971A2 (pt) 2017-06-13
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PH12014501595A1 (en) 2014-10-08

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