CU23526B6 - Método para la restauración morfofuncional de nervios periféricos en la neuropatía diabética - Google Patents
Método para la restauración morfofuncional de nervios periféricos en la neuropatía diabéticaInfo
- Publication number
- CU23526B6 CU23526B6 CU20060192A CU20060192A CU23526B6 CU 23526 B6 CU23526 B6 CU 23526B6 CU 20060192 A CU20060192 A CU 20060192A CU 20060192 A CU20060192 A CU 20060192A CU 23526 B6 CU23526 B6 CU 23526B6
- Authority
- CU
- Cuba
- Prior art keywords
- peripheral nerves
- restoration
- diabetic neuropathy
- morfofunctional
- manifestations
- Prior art date
Links
- 210000000578 peripheral nerve Anatomy 0.000 title abstract 3
- 208000032131 Diabetic Neuropathies Diseases 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 102000009024 Epidermal Growth Factor Human genes 0.000 abstract 4
- 101800003838 Epidermal growth factor Proteins 0.000 abstract 2
- 206010029240 Neuritis Diseases 0.000 abstract 2
- 229940116977 epidermal growth factor Drugs 0.000 abstract 2
- 230000008595 infiltration Effects 0.000 abstract 2
- 238000001764 infiltration Methods 0.000 abstract 2
- 230000000302 ischemic effect Effects 0.000 abstract 2
- VBEQCZHXXJYVRD-GACYYNSASA-N uroanthelone Chemical compound C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CS)C(=O)N[C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(C)C)[C@@H](C)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CCSC)NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)CNC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CS)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CS)NC(=O)CNC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(N)=O)C(C)C)[C@@H](C)CC)C1=CC=C(O)C=C1 VBEQCZHXXJYVRD-GACYYNSASA-N 0.000 abstract 2
- 229940035676 analgesics Drugs 0.000 abstract 1
- 229940035674 anesthetics Drugs 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 210000000609 ganglia Anatomy 0.000 abstract 1
- 239000003193 general anesthetic agent Substances 0.000 abstract 1
- 239000004005 microsphere Substances 0.000 abstract 1
- 208000005877 painful neuropathy Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1808—Epidermal growth factor [EGF] urogastrone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/485—Epidermal growth factor [EGF], i.e. urogastrone
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/12—Growth hormone, growth factor other than t-cell or b-cell growth factor, and growth hormone releasing factor; related peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
La presente invención es aplicable en medicina humana, y se relaciona con un método para la restauración morfofuncional de nervios periféricos en la neuropatía diabética de tipo sensitivo motora, dolorosa; y las manifestaciones de neuritis isquémica, mediante la infiltración del Factor de Crecimiento Epidérmico (del inglés Epidermal Growth Factor, abreviado EGF). También incluye una composición que comprende EGF, el que puede ser formulado junto a anestésicos o analgésicos, o encapsulado en microesferas; que se administra mediante infiltración en la periferia de troncos y/o ganglios neviosos, para la restauración morfofuncional de nervios periféricos en la neuropatía sensitivo-motora, dolorosa, así como las manifestaciones de neuritis isquémica.
Priority Applications (21)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CU20060192A CU23526B6 (es) | 2006-10-03 | 2006-10-03 | Método para la restauración morfofuncional de nervios periféricos en la neuropatía diabética |
| CN2007800422158A CN101573130B (zh) | 2006-10-03 | 2007-10-01 | 表皮生长因子用于在糖尿病性神经病中外周神经的形态功能恢复的用途 |
| PT07817382T PT2075004E (pt) | 2006-10-03 | 2007-10-01 | Uso de fator de crescimento epidérmico na restauração morfofuncional de nervos periféricos na neuropatia diabética |
| RU2009116646/15A RU2460536C2 (ru) | 2006-10-03 | 2007-10-01 | Применение эпидермального фактора роста для морфофункционального восстановления периферических нервов при диабетической невропатии |
| BRPI0719816A BRPI0719816B8 (pt) | 2006-10-03 | 2007-10-01 | uso do fator de crescimento epidérmico (egf) humano para preparar uma composição farmacêutica injetável para a restauração morfofuncional de nervos periféricos em neuropatia diabética e a referida composição |
| ARP070104350A AR063088A1 (es) | 2006-10-03 | 2007-10-01 | Uso del factor de crecimiento epidermico para la restauracion morfofuncoional de nervios perifericos en la neuropatia diabetica |
| US12/443,837 US8642552B2 (en) | 2006-10-03 | 2007-10-01 | Use of epidermal growth factor for the morphofunctional restoration of peripheral nerves in diabetic neuropathy |
| MX2009003678A MX2009003678A (es) | 2006-10-03 | 2007-10-01 | Uso del factor de crecimiento epidermico para la restauracion morfofuncional de nervios perifericos en la neuropatia diabetica. |
| JP2009530751A JP5508853B2 (ja) | 2006-10-03 | 2007-10-01 | 糖尿病性神経障害における末梢神経の形態機能的回復のための上皮増殖因子の使用 |
| ES07817382T ES2386058T3 (es) | 2006-10-03 | 2007-10-01 | Uso del factor del crecimiento epidérmico para la restauración morfofuncional de nervios periféricos en la neuropatía diabética |
| PL07817382T PL2075004T3 (pl) | 2006-10-03 | 2007-10-01 | Zastosowanie naskórkowego czynnika wzrostu do odbudowy morfofunkcjonalnej nerwów obwodowych w neuropatii cukrzycowej |
| AU2007304640A AU2007304640B2 (en) | 2006-10-03 | 2007-10-01 | Use of epidermal growth factor for the morphofunctional restoration of peripheral nerves in diabetic neuropathy |
| PCT/CU2007/000018 WO2008040260A1 (es) | 2006-10-03 | 2007-10-01 | Uso del factor de crecimiento epidérmico para la restauración morfofuncional de nervios periféricos en la neuropatía diabética |
| EP07817382A EP2075004B1 (en) | 2006-10-03 | 2007-10-01 | Use of epidermal growth factor for the morphofunctional restoration of peripheral nerves in diabetic neuropathy |
| CA2665117A CA2665117C (en) | 2006-10-03 | 2007-10-01 | Use of epidermal growth factor for the morphofunctional restoration of peripheral nerves in diabetic neuropathy |
| KR1020097009188A KR101464208B1 (ko) | 2006-10-03 | 2007-10-01 | 당뇨성 신경병증에서 말초 신경의 형태기능의 복원을 위한 상피 성장인자의 용도 |
| DK07817382.0T DK2075004T3 (da) | 2006-10-03 | 2007-10-01 | Anvendelse af epidermal vækstfaktor til morphofunktionel genoprettelse af perifere nerver ved diabetisk neuropati |
| AT07817382T ATE544462T1 (de) | 2006-10-03 | 2007-10-01 | Verwendung des epidermalen wachstumsfaktors zur morphofunktionellen wiederherstellung von peripheren nerven bei diabetischer neuropathie |
| CL200702862A CL2007002862A1 (es) | 2006-10-03 | 2007-10-03 | Uso del factor de crecimiento epidermico (egf) para tratar neuropatia sensitivo-motora, dolorosa y manifestaciones de neuritis isquemicas; composicion farmaceutica que comprende egf; y uso de la composicion antes dicha. |
| ZA200902311A ZA200902311B (en) | 2006-10-03 | 2009-04-02 | Use of epidermal growth factor for the morphofunctional restoration of peripheral nerves in diabetic neuropathy |
| US14/140,849 US9034826B2 (en) | 2006-10-03 | 2013-12-26 | Use of epidermal growth factor for the morphofunctional restoration of peripheral nerves in diabetic neuropathy |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CU20060192A CU23526B6 (es) | 2006-10-03 | 2006-10-03 | Método para la restauración morfofuncional de nervios periféricos en la neuropatía diabética |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CU23526B6 true CU23526B6 (es) | 2010-05-19 |
Family
ID=38925545
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CU20060192A CU23526B6 (es) | 2006-10-03 | 2006-10-03 | Método para la restauración morfofuncional de nervios periféricos en la neuropatía diabética |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US8642552B2 (es) |
| EP (1) | EP2075004B1 (es) |
| JP (1) | JP5508853B2 (es) |
| KR (1) | KR101464208B1 (es) |
| CN (1) | CN101573130B (es) |
| AR (1) | AR063088A1 (es) |
| AT (1) | ATE544462T1 (es) |
| AU (1) | AU2007304640B2 (es) |
| BR (1) | BRPI0719816B8 (es) |
| CA (1) | CA2665117C (es) |
| CL (1) | CL2007002862A1 (es) |
| CU (1) | CU23526B6 (es) |
| DK (1) | DK2075004T3 (es) |
| ES (1) | ES2386058T3 (es) |
| MX (1) | MX2009003678A (es) |
| PL (1) | PL2075004T3 (es) |
| PT (1) | PT2075004E (es) |
| RU (1) | RU2460536C2 (es) |
| WO (1) | WO2008040260A1 (es) |
| ZA (1) | ZA200902311B (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101252740B1 (ko) * | 2011-05-25 | 2013-04-11 | 연세대학교 산학협력단 | 센서 및 센싱방법 |
| EP2737895A1 (en) * | 2012-11-30 | 2014-06-04 | Praxis Pharmaceutical, S.A. | Microparticles with EGF, method of preparation and use |
| CA2891855A1 (en) * | 2012-12-21 | 2014-06-26 | Sykehuset Sorlandet Hf | Egfr targeted therapy of neurological disorders and pain |
| CA2920835A1 (en) | 2013-08-20 | 2015-02-26 | Anutra Medical, Inc. | Syringe fill system and method |
| IL312865B2 (en) | 2013-09-11 | 2025-06-01 | Eagle Biologics Inc | Liquid protein formulations containing viscosity-lowering agents |
| USD763433S1 (en) | 2014-06-06 | 2016-08-09 | Anutra Medical, Inc. | Delivery system cassette |
| USD750768S1 (en) | 2014-06-06 | 2016-03-01 | Anutra Medical, Inc. | Fluid administration syringe |
| USD774182S1 (en) | 2014-06-06 | 2016-12-13 | Anutra Medical, Inc. | Anesthetic delivery device |
| AU2015325055B2 (en) | 2014-10-01 | 2021-02-25 | Eagle Biologics, Inc. | Polysaccharide and nucleic acid formulations containing viscosity-lowering agents |
| RU2585421C1 (ru) * | 2014-12-24 | 2016-05-27 | Артур Владимирович Маргасов | Способ восстановления поврежденного нерва |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5130298A (en) * | 1989-05-16 | 1992-07-14 | Ethicon, Inc. | Stabilized compositions containing epidermal growth factor |
| SE9601243D0 (sv) | 1996-03-29 | 1996-03-29 | Hans Arne Hansson | Promotion of regeneration of organized tissues |
| AU2231399A (en) * | 1998-01-20 | 1999-08-02 | Aurx, Inc. | A herpes virus vector |
| US6444205B2 (en) * | 1998-09-30 | 2002-09-03 | Diacrin, Inc. | Transplantation of neural cells for the treatment of chronic pain or spasticity |
| SE9804064D0 (sv) | 1998-11-25 | 1998-11-25 | A & Science Invest Ab | Medicinal product and method for treatment of conditions affecting neural stem cells or progenitor cells |
| CA2365434A1 (en) * | 1999-04-15 | 2000-10-26 | St. Elizabeth's Medical Center Of Boston | Angiogenic growth factors for treatment of peripheral neuropathy |
| WO2002012335A2 (en) * | 2000-08-10 | 2002-02-14 | Pharmacia Corporation | A NEW EGF MOTIF REPEAT PROTEIN OBTAINED FROM A cDNA LIBRARY FROM HS-5 STROMAL CELL LINE |
| CU23157A1 (es) | 2001-01-03 | 2006-07-18 | Ct Ingenieria Genetica Biotech | COMPOSICION FARMACéUTICA PARA EL TRATAMIENTO DEL DANO TISULAR DEBIDO A FALTA DE IRRIGACION SANGUINEA ARTERIAL |
| DE60220894T2 (de) * | 2001-03-12 | 2008-02-28 | Institute Of Gene And Brain Science | Verwendung von interleukin-12 zur behandlung von nervenschäden |
| JP2006152001A (ja) * | 2001-03-12 | 2006-06-15 | Institute Of Gene & Brain Science | 神経損傷の治療薬 |
| CU23043A1 (es) * | 2001-12-20 | 2005-05-20 | Ct Ingenieria Genetica Biotech | Composicion farmaceutica que contiene factor de crecimiento epidrmico (egf) para la prevencion de la amputacion de pie diabetico. |
| US7465463B2 (en) | 2002-09-04 | 2008-12-16 | Polyheal, Ltd. | Compositions comprising microspheres with anti-inflammatory properties for healing of ocular tissues |
| US20070122487A1 (en) * | 2003-03-19 | 2007-05-31 | University Of Kentucky Research Foundation | (Poly(acryloyl-hydroxyethyl starch)-plga composition microspheres |
| CN103230415B (zh) * | 2003-04-25 | 2016-05-04 | 匹兹堡大学联邦制高等教育 | 用于促进和增强神经修复和再生的肌肉来源的细胞（mdc） |
| WO2006012707A1 (en) * | 2004-08-06 | 2006-02-09 | Gropep Limited | Method for treating diabetes |
| AU2006206194A1 (en) * | 2005-01-21 | 2006-07-27 | Northwestern University | Methods and compositions for encapsulation of cells |
| KR100765496B1 (ko) * | 2005-12-09 | 2007-10-10 | 경희대학교 산학협력단 | 히레귤린 베타1의 ｅｇｆ-성 도메인 펩타이드를 암호화하는ｄｎａ 서열을 포함하는 재조합 아데노바이러스 및 이를포함하는 신경세포 분화 및 재생용 약학 조성물 |
-
2006
- 2006-10-03 CU CU20060192A patent/CU23526B6/es active IP Right Grant
-
2007
- 2007-10-01 BR BRPI0719816A patent/BRPI0719816B8/pt not_active IP Right Cessation
- 2007-10-01 CN CN2007800422158A patent/CN101573130B/zh not_active Expired - Fee Related
- 2007-10-01 AT AT07817382T patent/ATE544462T1/de active
- 2007-10-01 AU AU2007304640A patent/AU2007304640B2/en not_active Ceased
- 2007-10-01 ES ES07817382T patent/ES2386058T3/es active Active
- 2007-10-01 PT PT07817382T patent/PT2075004E/pt unknown
- 2007-10-01 JP JP2009530751A patent/JP5508853B2/ja active Active
- 2007-10-01 MX MX2009003678A patent/MX2009003678A/es active IP Right Grant
- 2007-10-01 RU RU2009116646/15A patent/RU2460536C2/ru active
- 2007-10-01 DK DK07817382.0T patent/DK2075004T3/da active
- 2007-10-01 EP EP07817382A patent/EP2075004B1/en not_active Not-in-force
- 2007-10-01 PL PL07817382T patent/PL2075004T3/pl unknown
- 2007-10-01 KR KR1020097009188A patent/KR101464208B1/ko not_active Expired - Fee Related
- 2007-10-01 WO PCT/CU2007/000018 patent/WO2008040260A1/es not_active Ceased
- 2007-10-01 AR ARP070104350A patent/AR063088A1/es unknown
- 2007-10-01 CA CA2665117A patent/CA2665117C/en not_active Expired - Fee Related
- 2007-10-01 US US12/443,837 patent/US8642552B2/en not_active Expired - Fee Related
- 2007-10-03 CL CL200702862A patent/CL2007002862A1/es unknown
-
2009
- 2009-04-02 ZA ZA200902311A patent/ZA200902311B/xx unknown
-
2013
- 2013-12-26 US US14/140,849 patent/US9034826B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN101573130A (zh) | 2009-11-04 |
| CL2007002862A1 (es) | 2008-05-23 |
| RU2009116646A (ru) | 2010-11-10 |
| US8642552B2 (en) | 2014-02-04 |
| EP2075004A1 (en) | 2009-07-01 |
| ATE544462T1 (de) | 2012-02-15 |
| ZA200902311B (en) | 2010-04-28 |
| US20140105990A1 (en) | 2014-04-17 |
| WO2008040260A1 (es) | 2008-04-10 |
| RU2460536C2 (ru) | 2012-09-10 |
| US9034826B2 (en) | 2015-05-19 |
| CN101573130B (zh) | 2012-10-31 |
| MX2009003678A (es) | 2009-04-22 |
| EP2075004B1 (en) | 2012-02-08 |
| JP5508853B2 (ja) | 2014-06-04 |
| BRPI0719816B1 (pt) | 2018-04-24 |
| CA2665117A1 (en) | 2008-04-10 |
| AU2007304640B2 (en) | 2013-01-17 |
| KR101464208B1 (ko) | 2014-12-04 |
| PL2075004T3 (pl) | 2012-09-28 |
| DK2075004T3 (da) | 2012-05-14 |
| CA2665117C (en) | 2015-04-14 |
| AR063088A1 (es) | 2008-12-23 |
| JP2010505773A (ja) | 2010-02-25 |
| BRPI0719816A2 (pt) | 2015-09-08 |
| KR20090103862A (ko) | 2009-10-01 |
| US20100136062A1 (en) | 2010-06-03 |
| ES2386058T3 (es) | 2012-08-08 |
| PT2075004E (pt) | 2012-05-02 |
| BRPI0719816B8 (pt) | 2021-05-25 |
| AU2007304640A1 (en) | 2008-04-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR063088A1 (es) | Uso del factor de crecimiento epidermico para la restauracion morfofuncoional de nervios perifericos en la neuropatia diabetica | |
| ECSP12011631A (es) | Composición de insulina de acción prolongada | |
| ECSP077339A (es) | Capuchón para dispositivos para la administración de fármacos | |
| BRPI0915439B8 (pt) | composição de gel tópica, bem como uso de um agente ativo para tratamento de ceratose actínica em combinação com um agente ceratoliticamente ativo para preparação da referida composição | |
| CO6400181A2 (es) | Compuestos de tiazolopiridina moduladores de sirtuina | |
| PE20140105A1 (es) | Analogos deuterados de pridopidina utiles como estabilizadores dopaminergicos | |
| MX369259B (es) | Dosificacion oral de compuestos peptido similar al glaucon-1 (glp-1). | |
| DOP2006000057A (es) | Composición farmaceútica para el tratamiento del cáncer | |
| NI201400083A (es) | Compuesto de imidazopirrolidinona | |
| NI200800169A (es) | Uso de derivados de sulfamidas heterocíclicas benzo-fusionadas para el tratamiento del dolor | |
| MX382411B (es) | Soluciones midriáticas y antiinflamatorias inyectables, estables y libres de conservantes. | |
| UY30833A1 (es) | Nanoemulsion | |
| MX2020008468A (es) | Mejoramiento de autofagia o incremento de longevidad por administracion de urolitinas o precursores de las mismas. | |
| UY32543A (es) | Análogos de isoxazol-3(2h)-ona como agentes terapéuticos | |
| UY31170A1 (es) | Compuestos moduladores de sirtuina | |
| UY32923A (es) | Compuestos policíclicos como antagonistas del receptor de ácido lisofosfatídico | |
| BR112015019657A2 (pt) | composições tópicas e métodos de uso das mesmas | |
| MX366906B (es) | Purificacion de iduronato-2-sulfatasa. | |
| UY30158A1 (es) | Uso de derivados de benzo-heteroaril sulfamida para el tratamiento del dolor | |
| CO6470899A2 (es) | 2,4-diaminopirimidinas para el tratamiento de enfermedades caracterizadas por proliferación celular excesiva o normal | |
| CO6331308A2 (es) | Derivados de carboxamidaindazol con actividad sobre el receptor cb1 y composiciones farmaceuticas que los comprenden | |
| DOP2015000169A (es) | Compuestos tetracíclicos sustituidos con heterociclo y usos de los mismos para el tratamiento de enfermedades víricas | |
| NI201100117A (es) | Antagonistas de 4 -- azetidinil - 1 - heteroaril - ciclohexanol del ccr2. | |
| PE20121556A1 (es) | 3,6-diazabiciclo[3.1.1]heptanos como ligandos de receptores nicotinicos neuronales de acetilcolina | |
| MX2023012851A (es) | Métodos de tratamiento y seguimiento de la enfermedad de parkinson. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant of patent |