CU24095B1 - ISOLATED MONOCLONAL ANTIBODY FOR PBP2a PROTEINS - Google Patents

ISOLATED MONOCLONAL ANTIBODY FOR PBP2a PROTEINS

Info

Publication number
CU24095B1
CU24095B1 CU2012000026A CU20120026A CU24095B1 CU 24095 B1 CU24095 B1 CU 24095B1 CU 2012000026 A CU2012000026 A CU 2012000026A CU 20120026 A CU20120026 A CU 20120026A CU 24095 B1 CU24095 B1 CU 24095B1
Authority
CU
Cuba
Prior art keywords
pbp2a
proteins
monoclonal antibody
isolated monoclonal
pbp2a proteins
Prior art date
Application number
CU2012000026A
Other languages
Spanish (es)
Other versions
CU20120026A7 (en
Inventor
José Procópio Moreno Senna
Jo O Luiz Sampaio Qufiroz
Nadia Maria Batoreau
Maria Da Glória Martin Teixeira
Original Assignee
Fundaç O Oswaldo Cruz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from BRPI0914508-7A external-priority patent/BRPI0914508B1/en
Application filed by Fundaç O Oswaldo Cruz filed Critical Fundaç O Oswaldo Cruz
Priority claimed from PCT/BR2010/000263 external-priority patent/WO2011017791A1/en
Publication of CU20120026A7 publication Critical patent/CU20120026A7/en
Publication of CU24095B1 publication Critical patent/CU24095B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Gram-positive bacteria
    • C07K16/1271—Micrococcaceae (F); Staphylococcaceae (F), e.g. Staphylococcus (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

La presente invención se refiere a anticuerpos monoclonales capaces de reconocer y unirse a proteínas PBP2a y PBP5 y otras proteínas que presentan secuencias homólogas a PBP2a, incluyendo los patógenos Staphylococcus aureus resistentes a meticilina-MRSA y Enterococcus faecalis.The present invention relates to monoclonal antibodies capable of recognizing and binding to PBP2a and PBP5 proteins and other proteins that have sequences homologous to PBP2a, including the pathogens Staphylococcus aureus resistant to methicillin-MRSA and Enterococcus faecalis.

CU2012000026A 2009-08-10 2010-08-10 ISOLATED MONOCLONAL ANTIBODY FOR PBP2a PROTEINS CU24095B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BRPI0914508-7A BRPI0914508B1 (en) 2009-08-10 2009-08-10 Monoclonal Antibodies to PBP2a PROTEIN, AND PHARMACEUTICAL COMPOSITION
PCT/BR2010/000263 WO2011017791A1 (en) 2009-08-10 2010-08-10 Monoclonal antibodies against the pbp2-a protein and homologous sequences for the treatment of infections by and immunodiagnostics of bacteria of the firmicutes phylum

Publications (2)

Publication Number Publication Date
CU20120026A7 CU20120026A7 (en) 2012-06-21
CU24095B1 true CU24095B1 (en) 2015-04-29

Family

ID=45896895

Family Applications (2)

Application Number Title Priority Date Filing Date
CU20140101A CU24180B1 (en) 2009-08-10 2010-08-10 MONOCLONAL ANTIBODY ISOLATED FOR PROTEIN PBP5
CU2012000026A CU24095B1 (en) 2009-08-10 2010-08-10 ISOLATED MONOCLONAL ANTIBODY FOR PBP2a PROTEINS

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CU20140101A CU24180B1 (en) 2009-08-10 2010-08-10 MONOCLONAL ANTIBODY ISOLATED FOR PROTEIN PBP5

Country Status (6)

Country Link
JP (1) JP5785544B2 (en)
CN (1) CN102741281B (en)
AU (1) AU2010282162B2 (en)
CA (1) CA2770771C (en)
CU (2) CU24180B1 (en)
SG (1) SG178346A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3415160B1 (en) * 2014-03-04 2021-08-18 Klinikum der Universität München Polypeptides derived from enterococcus and their use for vaccination and the generation of therapeutic antibodies
CN105315367B (en) * 2014-07-29 2019-01-29 广州瑞博奥生物科技有限公司 For detecting the enzyme linked immunological kit of methicillin-resistant staphylococcus aureus
BR102020016890A2 (en) * 2020-08-19 2022-05-03 Fundação Oswaldo Cruz Protein, polynucleotide, vector, host cell, composition, method of treating a disease, in vitro method of prognosticating multiple sclerosis, and, use of a protein or composition
CN113150139B (en) * 2021-02-01 2022-09-09 深圳市龙华区疾病预防控制中心 A kind of PBP2a monoclonal antibody and its preparation method and application

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003503015A (en) * 1999-05-03 2003-01-28 メダレツクス・インコーポレーテツド Human antibodies to Staphylococcus aureus

Also Published As

Publication number Publication date
CA2770771A1 (en) 2011-02-17
RU2012108941A (en) 2013-09-20
CN102741281B (en) 2015-02-25
AU2010282162B2 (en) 2016-06-02
CU20140101A7 (en) 2015-01-29
SG178346A1 (en) 2012-03-29
CU24180B1 (en) 2016-04-25
JP2013501732A (en) 2013-01-17
AU2010282162A8 (en) 2012-05-24
CN102741281A (en) 2012-10-17
AU2010282162A1 (en) 2012-04-05
CA2770771C (en) 2019-12-03
JP5785544B2 (en) 2015-09-30
CU20120026A7 (en) 2012-06-21
HK1176077A1 (en) 2013-07-19

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Legal Events

Date Code Title Description
FG Grant of patent