CU24095B1 - ANTICUERPO MONOCLONAL AISLADO PARA PROTEÍNAS PBP2a - Google Patents

ANTICUERPO MONOCLONAL AISLADO PARA PROTEÍNAS PBP2a

Info

Publication number
CU24095B1
CU24095B1 CU2012000026A CU20120026A CU24095B1 CU 24095 B1 CU24095 B1 CU 24095B1 CU 2012000026 A CU2012000026 A CU 2012000026A CU 20120026 A CU20120026 A CU 20120026A CU 24095 B1 CU24095 B1 CU 24095B1
Authority
CU
Cuba
Prior art keywords
pbp2a
proteins
monoclonal antibody
isolated monoclonal
pbp2a proteins
Prior art date
Application number
CU2012000026A
Other languages
English (en)
Other versions
CU20120026A7 (es
Inventor
José Procópio Moreno Senna
Jo O Luiz Sampaio Qufiroz
Nadia Maria Batoreau
Maria Da Glória Martin Teixeira
Original Assignee
Fundaç O Oswaldo Cruz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from BRPI0914508-7A external-priority patent/BRPI0914508B1/pt
Application filed by Fundaç O Oswaldo Cruz filed Critical Fundaç O Oswaldo Cruz
Priority claimed from PCT/BR2010/000263 external-priority patent/WO2011017791A1/pt
Publication of CU20120026A7 publication Critical patent/CU20120026A7/es
Publication of CU24095B1 publication Critical patent/CU24095B1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Gram-positive bacteria
    • C07K16/1271—Micrococcaceae (F); Staphylococcaceae (F), e.g. Staphylococcus (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

La presente invención se refiere a anticuerpos monoclonales capaces de reconocer y unirse a proteínas PBP2a y PBP5 y otras proteínas que presentan secuencias homólogas a PBP2a, incluyendo los patógenos Staphylococcus aureus resistentes a meticilina-MRSA y Enterococcus faecalis.
CU2012000026A 2009-08-10 2010-08-10 ANTICUERPO MONOCLONAL AISLADO PARA PROTEÍNAS PBP2a CU24095B1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BRPI0914508-7A BRPI0914508B1 (pt) 2009-08-10 2009-08-10 ANTICORPOS MONOCLONAIS PARA A PROTEÍNA PBP2a, E, COMPOSIÇÃO FARMACÊUTICA
PCT/BR2010/000263 WO2011017791A1 (pt) 2009-08-10 2010-08-10 Anticorpos monoclonais para a proteína pbp2-a e sequências homólogas para o tratamento de infeçcões e imunodiagnóstico em bactérias do filo firmicutes

Publications (2)

Publication Number Publication Date
CU20120026A7 CU20120026A7 (es) 2012-06-21
CU24095B1 true CU24095B1 (es) 2015-04-29

Family

ID=45896895

Family Applications (2)

Application Number Title Priority Date Filing Date
CU20140101A CU24180B1 (es) 2009-08-10 2010-08-10 Anticuerpo monoclonal aislado para proteina pbp5
CU2012000026A CU24095B1 (es) 2009-08-10 2010-08-10 ANTICUERPO MONOCLONAL AISLADO PARA PROTEÍNAS PBP2a

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CU20140101A CU24180B1 (es) 2009-08-10 2010-08-10 Anticuerpo monoclonal aislado para proteina pbp5

Country Status (6)

Country Link
JP (1) JP5785544B2 (es)
CN (1) CN102741281B (es)
AU (1) AU2010282162B2 (es)
CA (1) CA2770771C (es)
CU (2) CU24180B1 (es)
SG (1) SG178346A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3415160B1 (en) * 2014-03-04 2021-08-18 Klinikum der Universität München Polypeptides derived from enterococcus and their use for vaccination and the generation of therapeutic antibodies
CN105315367B (zh) * 2014-07-29 2019-01-29 广州瑞博奥生物科技有限公司 用于检测耐甲氧西林金黄色葡萄球菌的酶联免疫试剂盒
BR102020016890A2 (pt) * 2020-08-19 2022-05-03 Fundação Oswaldo Cruz Proteina, polinucleotídeo, vetor, célula hospedeira, composição, método para tratar uma doença, método in vitro para prognosticar esclerose múltipla, e, uso de uma proteína ou composição
CN113150139B (zh) * 2021-02-01 2022-09-09 深圳市龙华区疾病预防控制中心 一种PBP2a单克隆抗体及其制备方法和应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003503015A (ja) * 1999-05-03 2003-01-28 メダレツクス・インコーポレーテツド スタフィロコッカス・アウレウスに対するヒト抗体

Also Published As

Publication number Publication date
CA2770771A1 (en) 2011-02-17
RU2012108941A (ru) 2013-09-20
CN102741281B (zh) 2015-02-25
AU2010282162B2 (en) 2016-06-02
CU20140101A7 (es) 2015-01-29
SG178346A1 (en) 2012-03-29
CU24180B1 (es) 2016-04-25
JP2013501732A (ja) 2013-01-17
AU2010282162A8 (en) 2012-05-24
CN102741281A (zh) 2012-10-17
AU2010282162A1 (en) 2012-04-05
CA2770771C (en) 2019-12-03
JP5785544B2 (ja) 2015-09-30
CU20120026A7 (es) 2012-06-21
HK1176077A1 (en) 2013-07-19

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