CY1120088T1 - Παραγωγα τυπου αζαϊνδαζολιου ή διαζαϊνδαζολιου ως φαρμακo - Google Patents

Παραγωγα τυπου αζαϊνδαζολιου ή διαζαϊνδαζολιου ως φαρμακo

Info

Publication number: CY1120088T1
Authority: CY; Cyprus
Prior art keywords: diazandazolo; azazine; medicine; type products; mixture
Prior art date: 2011-01-27

Application number

CY20181100338T

Other languages

Greek (el)

English (en)

Inventor

El Bachir Kaloun

Karim Bedjeguelal

Rémi RABOT

Anna Kruczynski

Philippe Schmitt

Michel Perez

Nicolas Rahier

Original Assignee

Pierre Fabre Médicament

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2011-01-27

Filing date

2018-03-26

Publication date

2018-12-12

2018-03-26 Application filed by Pierre Fabre Médicament filed Critical Pierre Fabre Médicament

2018-12-12 Publication of CY1120088T1 publication Critical patent/CY1120088T1/el

Links

239000000203 mixture Substances 0.000 abstract 2
HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
208000024827 Alzheimer disease Diseases 0.000 abstract 1
206010061218 Inflammation Diseases 0.000 abstract 1
206010028980 Neoplasm Diseases 0.000 abstract 1
201000011510 cancer Diseases 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000004054 inflammatory process Effects 0.000 abstract 1
229940043355 kinase inhibitor Drugs 0.000 abstract 1
229940126601 medicinal product Drugs 0.000 abstract 1
230000004770 neurodegeneration Effects 0.000 abstract 1
208000015122 neurodegenerative disease Diseases 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
239000003757 phosphotransferase inhibitor Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
239000012453 solvate Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)

CY20181100338T 2011-01-27 2018-03-26 Παραγωγα τυπου αζαϊνδαζολιου ή διαζαϊνδαζολιου ως φαρμακo CY1120088T1 (el)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR1150651A FR2970967B1 (fr)	2011-01-27	2011-01-27	Derives de type azaindazole ou diazaindazole comme medicament
PCT/EP2012/051283 WO2012101239A1 (en)	2011-01-27	2012-01-27	Derivatives of azaindazole or diazaindazole type as medicament

Publications (1)

Publication Number	Publication Date
CY1120088T1 true CY1120088T1 (el)	2018-12-12

Family

ID=44318089

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CY20181100338T CY1120088T1 (el)	2011-01-27	2018-03-26	Παραγωγα τυπου αζαϊνδαζολιου ή διαζαϊνδαζολιου ως φαρμακo

Country Status (30)

Country	Link
US (2)	US20130172360A1 (2)
EP (1)	EP2668184B1 (2)
JP (1)	JP5931926B2 (2)
KR (2)	KR20180122028A (2)
CN (1)	CN103339129B (2)
AR (1)	AR084935A1 (2)
AU (1)	AU2012210467B2 (2)
BR (1)	BR112013018852B1 (2)
CA (1)	CA2823824C (2)
CY (1)	CY1120088T1 (2)
DK (1)	DK2668184T3 (2)
ES (1)	ES2661695T3 (2)
FR (1)	FR2970967B1 (2)
HR (1)	HRP20180524T1 (2)
HU (1)	HUE037153T2 (2)
IL (2)	IL227496B (2)
LT (1)	LT2668184T (2)
MA (1)	MA34903B1 (2)
MX (1)	MX356411B (2)
MY (1)	MY180666A (2)
PL (1)	PL2668184T3 (2)
PT (1)	PT2668184T (2)
RS (1)	RS57101B1 (2)
RU (1)	RU2600976C2 (2)
SI (1)	SI2668184T1 (2)
TN (1)	TN2013000293A1 (2)
TR (1)	TR201802944T4 (2)
TW (1)	TWI546303B (2)
UA (1)	UA109698C2 (2)
WO (1)	WO2012101239A1 (2)

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US8754114B2 (en)	2010-12-22	2014-06-17	Incyte Corporation	Substituted imidazopyridazines and benzimidazoles as inhibitors of FGFR3
FR2970967B1 (fr) *	2011-01-27	2013-02-15	Pf Medicament	Derives de type azaindazole ou diazaindazole comme medicament
EP2817292B1 (en)	2012-02-22	2019-12-18	Sanford-Burnham Medical Research Institute	Sulfonamide compounds and uses as tnap inhibitors
ES2704744T3 (es)	2012-06-13	2019-03-19	Incyte Holdings Corp	Compuestos tricíclicos sustituidos como inhibidores de FGFR
EP2689778A1 (en) *	2012-07-27	2014-01-29	Pierre Fabre Medicament	Derivatives of azaindoles or diazaindoles for treating pain
EP2689779A1 (en) *	2012-07-27	2014-01-29	Pierre Fabre Medicament	Derivatives of azaindazole or diazaindazole type for treating a cancer overexpressing trk
US9388185B2 (en)	2012-08-10	2016-07-12	Incyte Holdings Corporation	Substituted pyrrolo[2,3-b]pyrazines as FGFR inhibitors
US9266892B2 (en)	2012-12-19	2016-02-23	Incyte Holdings Corporation	Fused pyrazoles as FGFR inhibitors
EA035095B1 (ru)	2013-04-19	2020-04-27	Инсайт Холдингс Корпорейшн	Бициклические гетероциклы в качестве ингибиторов fgfr
US10851105B2 (en)	2014-10-22	2020-12-01	Incyte Corporation	Bicyclic heterocycles as FGFR4 inhibitors
US10336707B2 (en)	2014-12-16	2019-07-02	Eudendron S.R.L.	Heterocyclic derivatives modulating activity of certain protein kinases
MX373169B (es)	2015-02-20	2020-04-24	Incyte Holdings Corp	Heterociclos bicíclicos como inhibidores de receptores del factor de crecimiento fibroblástico (fgfr).
WO2016134294A1 (en)	2015-02-20	2016-08-25	Incyte Corporation	Bicyclic heterocycles as fgfr4 inhibitors
MA41551A (fr)	2015-02-20	2017-12-26	Incyte Corp	Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
US10211205B2 (en) *	2016-04-27	2019-02-19	International Business Machines Corporation	Field effect transistor structure for reducing contact resistance
CN108570052A (zh) *	2017-03-13	2018-09-25	中国科学院上海药物研究所	五元杂环并吡嗪化合物、制备方法、中间体、组合和应用
AR111960A1 (es)	2017-05-26	2019-09-04	Incyte Corp	Formas cristalinas de un inhibidor de fgfr y procesos para su preparación
CA3098988A1 (en)	2018-05-02	2019-11-07	Jw Pharmaceutical Corporation	Heterocycle derivative
MA52493A (fr)	2018-05-04	2021-03-10	Incyte Corp	Sels d'un inhibiteur de fgfr
CR20200590A (es)	2018-05-04	2021-04-26	Incyte Corp	Formas sólidas de un inhibidor de fgfr y procesos para prepararlas
WO2020185532A1 (en)	2019-03-08	2020-09-17	Incyte Corporation	Methods of treating cancer with an fgfr inhibitor
EP3725777A1 (en) *	2019-04-17	2020-10-21	Rottapharm Biotech S.r.l.	Benzo- and pyrido-pyrazoles as protein kinase inhibitors
WO2021007269A1 (en)	2019-07-09	2021-01-14	Incyte Corporation	Bicyclic heterocycles as fgfr inhibitors
WO2021009568A1 (en)	2019-07-17	2021-01-21	2692372 Ontario, Inc.	Benzenesulfonamide derivatives and uses thereof
WO2021067374A1 (en)	2019-10-01	2021-04-08	Incyte Corporation	Bicyclic heterocycles as fgfr inhibitors
TWI891666B (zh)	2019-10-14	2025-08-01	美商英塞特公司	作為ｆｇｆｒ抑制劑之雙環雜環
WO2021076728A1 (en)	2019-10-16	2021-04-22	Incyte Corporation	Bicyclic heterocycles as fgfr inhibitors
EP4069696A1 (en)	2019-12-04	2022-10-12	Incyte Corporation	Tricyclic heterocycles as fgfr inhibitors
BR112022010664A2 (pt)	2019-12-04	2022-08-16	Incyte Corp	Derivados de um inibidor de fgfr
EP4085061A1 (en) *	2019-12-31	2022-11-09	IFM Due, Inc.	Compounds and compositions for treating conditions associated with sting activity
WO2021146424A1 (en)	2020-01-15	2021-07-22	Incyte Corporation	Bicyclic heterocycles as fgfr inhibitors
WO2021197467A1 (zh) *	2020-04-02	2021-10-07	上海华汇拓医药科技有限公司	多靶点的抗肿瘤化合物及其制备方法和应用
GB2617477A (en) *	2020-11-20	2023-10-11	2692372 Ontario Inc	Benzenesulfonamide derivatives and uses thereof
TW202304459A (zh)	2021-04-12	2023-02-01	美商英塞特公司	包含ｆｇｆｒ抑制劑及ｎｅｃｔｉｎ－４靶向劑之組合療法
EP4352059A1 (en)	2021-06-09	2024-04-17	Incyte Corporation	Tricyclic heterocycles as fgfr inhibitors
WO2022261159A1 (en)	2021-06-09	2022-12-15	Incyte Corporation	Tricyclic heterocycles as fgfr inhibitors

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AU2003245700A1 (en) *	2002-02-12	2003-09-04	Glaxo Group Limited	Pyrazolopyridine derivatives
DE102004061288A1 (de) *	2004-12-14	2006-06-29	Schering Ag	3-Amino-Pyrazolo[3,4b]pyridine als Inhibitoren von Proteintyrosinkinasen, deren Herstellung und Verwendung als Arzneimittel
RU2008110941A (ru) *	2005-08-25	2009-09-27	Ф.Хоффманн-Ля Рош Аг (Ch)	ИНГИБИТОРЫ КИНАЗЫ p38 МАР И СПОСОБЫ ИХ ПРИМЕНЕНИЯ
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FR2970967B1 (fr) *	2011-01-27	2013-02-15	Pf Medicament	Derives de type azaindazole ou diazaindazole comme medicament

2011
- 2011-01-27 FR FR1150651A patent/FR2970967B1/fr active Active
2012
- 2012-01-20 TW TW101102531A patent/TWI546303B/zh active
- 2012-01-27 KR KR1020187031264A patent/KR20180122028A/ko not_active Ceased
- 2012-01-27 HR HRP20180524TT patent/HRP20180524T1/hr unknown
- 2012-01-27 PT PT127018844T patent/PT2668184T/pt unknown
- 2012-01-27 RS RS20180418A patent/RS57101B1/sr unknown
- 2012-01-27 KR KR1020137022330A patent/KR101923751B1/ko not_active Expired - Fee Related
- 2012-01-27 PL PL12701884T patent/PL2668184T3/pl unknown
- 2012-01-27 HU HUE12701884A patent/HUE037153T2/hu unknown
- 2012-01-27 MY MYPI2013002799A patent/MY180666A/en unknown
- 2012-01-27 MA MA36177A patent/MA34903B1/fr unknown
- 2012-01-27 TR TR2018/02944T patent/TR201802944T4/tr unknown
- 2012-01-27 JP JP2013550886A patent/JP5931926B2/ja active Active
- 2012-01-27 WO PCT/EP2012/051283 patent/WO2012101239A1/en not_active Ceased
- 2012-01-27 ES ES12701884.4T patent/ES2661695T3/es active Active
- 2012-01-27 US US13/823,658 patent/US20130172360A1/en not_active Abandoned
- 2012-01-27 CA CA2823824A patent/CA2823824C/en active Active
- 2012-01-27 AR ARP120100272A patent/AR084935A1/es active IP Right Grant
- 2012-01-27 RU RU2013138624/04A patent/RU2600976C2/ru active
- 2012-01-27 UA UAA201310425A patent/UA109698C2/ru unknown
- 2012-01-27 AU AU2012210467A patent/AU2012210467B2/en not_active Ceased
- 2012-01-27 CN CN201280006671.8A patent/CN103339129B/zh not_active Expired - Fee Related
- 2012-01-27 SI SI201231273T patent/SI2668184T1/en unknown
- 2012-01-27 LT LTEP12701884.4T patent/LT2668184T/lt unknown
- 2012-01-27 MX MX2013008673A patent/MX356411B/es active IP Right Grant
- 2012-01-27 BR BR112013018852-9A patent/BR112013018852B1/pt not_active IP Right Cessation
- 2012-01-27 EP EP12701884.4A patent/EP2668184B1/en active Active
- 2012-01-27 DK DK12701884.4T patent/DK2668184T3/en active
- 2012-11-27 US US13/686,334 patent/US8883821B2/en active Active
2013
- 2013-07-11 TN TNP2013000293A patent/TN2013000293A1/fr unknown
- 2013-07-16 IL IL227496A patent/IL227496B/en active IP Right Grant
2018
- 2018-02-26 IL IL257748A patent/IL257748B/en active IP Right Grant
- 2018-03-26 CY CY20181100338T patent/CY1120088T1/el unknown

Also Published As

Publication number	Publication date
HRP20180524T1 (hr)	2018-05-04
HUE037153T2 (hu)	2018-08-28
TWI546303B (zh)	2016-08-21
RU2600976C2 (ru)	2016-10-27
FR2970967B1 (fr)	2013-02-15
TN2013000293A1 (en)	2015-01-20
BR112013018852B1 (pt)	2021-12-21
CA2823824A1 (en)	2012-08-02
ES2661695T3 (es)	2018-04-03
IL257748A (en)	2018-04-30
HK1186737A1 (en)	2014-03-21
AU2012210467A1 (en)	2013-09-12
IL257748B (en)	2020-06-30
RU2013138624A (ru)	2015-03-10
MX356411B (es)	2018-05-24
SI2668184T1 (en)	2018-06-29
NZ614432A (en)	2015-03-27
MY180666A (en)	2020-12-04
DK2668184T3 (en)	2018-03-12
EP2668184B1 (en)	2018-01-10
TR201802944T4 (tr)	2018-03-21
KR20140014147A (ko)	2014-02-05
UA109698C2 (xx)	2015-09-25
US8883821B2 (en)	2014-11-11
BR112013018852A2 (pt)	2017-08-15
KR20180122028A (ko)	2018-11-09
MX2013008673A (es)	2013-12-02
US20130172360A1 (en)	2013-07-04
PT2668184T (pt)	2018-03-13
US20130085144A1 (en)	2013-04-04
CN103339129A (zh)	2013-10-02
PL2668184T3 (pl)	2018-06-29
EP2668184A1 (en)	2013-12-04
KR101923751B1 (ko)	2018-11-29
AU2012210467B2 (en)	2016-07-07
IL227496A0 (en)	2013-09-30
FR2970967A1 (fr)	2012-08-03
CN103339129B (zh)	2015-07-29
MA34903B1 (fr)	2014-02-01
JP5931926B2 (ja)	2016-06-08
LT2668184T (lt)	2018-04-10
CA2823824C (en)	2018-12-11
JP2014503574A (ja)	2014-02-13
TW201247664A (en)	2012-12-01
WO2012101239A1 (en)	2012-08-02
AR084935A1 (es)	2013-07-10
RS57101B1 (sr)	2018-06-29
IL227496B (en)	2019-02-28

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