CY1122020T1 - Μορια δεσμευσης σε cd3 ικανα να δεσμευονται σε ανθρωπινα και μη ανθρωπινα cd3 - Google Patents
Μορια δεσμευσης σε cd3 ικανα να δεσμευονται σε ανθρωπινα και μη ανθρωπινα cd3Info
- Publication number
- CY1122020T1 CY1122020T1 CY20191100442T CY191100442T CY1122020T1 CY 1122020 T1 CY1122020 T1 CY 1122020T1 CY 20191100442 T CY20191100442 T CY 20191100442T CY 191100442 T CY191100442 T CY 191100442T CY 1122020 T1 CY1122020 T1 CY 1122020T1
- Authority
- CY
- Cyprus
- Prior art keywords
- human
- bind
- binding molecules
- binding
- relates
- Prior art date
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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- C—CHEMISTRY; METALLURGY
- C03—GLASS; MINERAL OR SLAG WOOL
- C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
- C03C17/00—Surface treatment of glass, not in the form of fibres or filaments, by coating
- C03C17/34—Surface treatment of glass, not in the form of fibres or filaments, by coating with at least two coatings having different compositions
- C03C17/36—Surface treatment of glass, not in the form of fibres or filaments, by coating with at least two coatings having different compositions at least one coating being a metal
- C03C17/38—Surface treatment of glass, not in the form of fibres or filaments, by coating with at least two coatings having different compositions at least one coating being a metal at least one coating being a coating of an organic material
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2809—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
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- C—CHEMISTRY; METALLURGY
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- C03C17/00—Surface treatment of glass, not in the form of fibres or filaments, by coating
- C03C17/34—Surface treatment of glass, not in the form of fibres or filaments, by coating with at least two coatings having different compositions
- C03C17/42—Surface treatment of glass, not in the form of fibres or filaments, by coating with at least two coatings having different compositions at least one coating of an organic material and at least one non-metal coating
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- C—CHEMISTRY; METALLURGY
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- C07K16/2827—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
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- C—CHEMISTRY; METALLURGY
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- C03C2217/00—Coatings on glass
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- C03C2217/00—Coatings on glass
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- C03C2217/00—Coatings on glass
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- C03C2217/43—Coatings comprising at least one inhomogeneous layer consisting of a dispersed phase in a continuous phase
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- C07—ORGANIC CHEMISTRY
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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Abstract
Η παρούσα εφεύρεση σχετίζεται με μόρια δέσμευσης του CD3 ικανά να δεσμεύονται σε ανθρώπινο και μη ανθρώπινο CD3, και ειδικότερα με τέτοια μόρια που έχουν διασταυρούμενη αντίδραση με το CD3 ενός μη ανθρώπινου θηλαστικού (π.χ., ένας πίθηκος cynomolgus). Η εφεύρεση επίσης αναφέρεται σε χρήσεις τέτοιων αντισωμάτων και θραυσμάτων δέσμευσης αντιγόνου στη θεραπεία του καρκίνου, αυτοάνοσων και/ή φλεγμονωδών νόσων και άλλων καταστάσεων.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161488716P | 2011-05-21 | 2011-05-21 | |
| US201161530353P | 2011-09-01 | 2011-09-01 | |
| PCT/US2012/038219 WO2012162067A2 (en) | 2011-05-21 | 2012-05-16 | Cd3-binding molecules capable of binding to human and non-human cd3 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1122020T1 true CY1122020T1 (el) | 2020-10-14 |
Family
ID=47217980
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20191100442T CY1122020T1 (el) | 2011-05-21 | 2019-04-23 | Μορια δεσμευσης σε cd3 ικανα να δεσμευονται σε ανθρωπινα και μη ανθρωπινα cd3 |
Country Status (33)
| Country | Link |
|---|---|
| US (5) | US9587021B2 (el) |
| EP (2) | EP2714733B1 (el) |
| JP (4) | JP6141831B2 (el) |
| KR (2) | KR102060389B1 (el) |
| CN (3) | CN107827985A (el) |
| AU (3) | AU2012259161B2 (el) |
| BR (2) | BR122016016837A2 (el) |
| CA (1) | CA2836857C (el) |
| CL (3) | CL2013003329A1 (el) |
| CO (1) | CO6970560A2 (el) |
| CY (1) | CY1122020T1 (el) |
| DK (1) | DK2714733T3 (el) |
| EA (1) | EA033677B1 (el) |
| EC (1) | ECSP13013101A (el) |
| ES (1) | ES2732213T3 (el) |
| HR (1) | HRP20190756T1 (el) |
| HU (1) | HUE044209T2 (el) |
| IL (3) | IL229575B (el) |
| LT (1) | LT2714733T (el) |
| MA (1) | MA35174B1 (el) |
| ME (1) | ME03440B (el) |
| MX (2) | MX391107B (el) |
| MY (1) | MY173899A (el) |
| NZ (1) | NZ703939A (el) |
| PL (1) | PL2714733T4 (el) |
| PT (1) | PT2714733T (el) |
| RS (1) | RS58765B1 (el) |
| SG (3) | SG10201703425RA (el) |
| SI (1) | SI2714733T1 (el) |
| SM (1) | SMT201900239T1 (el) |
| UA (3) | UA115402C2 (el) |
| WO (1) | WO2012162067A2 (el) |
| ZA (1) | ZA201308602B (el) |
Families Citing this family (226)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9963510B2 (en) | 2005-04-15 | 2018-05-08 | Macrogenics, Inc. | Covalent diabodies and uses thereof |
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