CY1421A - N-substituted ergoline-and 9,10 didehydro-ergoline-8-carboxamide-and-8-aminomethyl derivatives,their production and their pharmaceutical composition - Google Patents

N-substituted ergoline-and 9,10 didehydro-ergoline-8-carboxamide-and-8-aminomethyl derivatives,their production and their pharmaceutical composition Download PDF

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Publication number
CY1421A
CY1421A CY1421A CY142188A CY1421A CY 1421 A CY1421 A CY 1421A CY 1421 A CY1421 A CY 1421A CY 142188 A CY142188 A CY 142188A CY 1421 A CY1421 A CY 1421A
Authority
CY
Cyprus
Prior art keywords
compound
carboxamide
methyl
formula
alkyl
Prior art date
Application number
CY1421A
Other languages
English (en)
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of CY1421A publication Critical patent/CY1421A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C07D457/06—Lysergic acid amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CY1421A 1981-11-04 1988-09-02 N-substituted ergoline-and 9,10 didehydro-ergoline-8-carboxamide-and-8-aminomethyl derivatives,their production and their pharmaceutical composition CY1421A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH7056/81A CH653333A5 (de) 1981-11-04 1981-11-04 N-substituierte ergolin- und 9,10-didehydroergolinderivate, ihre herstellung und sie enthaltende arzneimittel.

Publications (1)

Publication Number Publication Date
CY1421A true CY1421A (en) 1988-09-02

Family

ID=4319237

Family Applications (1)

Application Number Title Priority Date Filing Date
CY1421A CY1421A (en) 1981-11-04 1988-09-02 N-substituted ergoline-and 9,10 didehydro-ergoline-8-carboxamide-and-8-aminomethyl derivatives,their production and their pharmaceutical composition

Country Status (27)

Country Link
US (1) US4783464A (fr)
JP (1) JPS5885885A (fr)
AT (1) AT382374B (fr)
AU (1) AU561250B2 (fr)
BE (1) BE894844A (fr)
CA (1) CA1193249A (fr)
CH (1) CH653333A5 (fr)
CY (1) CY1421A (fr)
DE (1) DE3239788A1 (fr)
DK (1) DK486582A (fr)
ES (1) ES517082A0 (fr)
FI (1) FI71735C (fr)
FR (1) FR2516084A1 (fr)
GB (1) GB2108502B (fr)
HK (1) HK37188A (fr)
HU (1) HU187798B (fr)
IE (1) IE54122B1 (fr)
IL (1) IL67156A (fr)
IT (1) IT1189409B (fr)
KE (1) KE3797A (fr)
MY (1) MY8600310A (fr)
NL (1) NL8204213A (fr)
NZ (1) NZ202363A (fr)
PH (1) PH20595A (fr)
PT (1) PT75773A (fr)
SE (1) SE450122B (fr)
ZA (1) ZA828104B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4902691A (en) * 1988-12-19 1990-02-20 Eli Lilly And Company Heteroalkylamides of (8-β)-1-alkyl-6-(substituted)ergolines useful for blocking 5HT2 receptors

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3957785A (en) * 1971-12-02 1976-05-18 Societa' Farmaceutici Italia S.P.A. Bβ-Pyrimidino-aminomethyl-10α-ergoline and 10α-methoxyergoline derivatives
BE792515A (fr) * 1971-12-10 1973-06-08 Sandoz Sa Nouveaux derives de l'acide lysergique, leur preparation et leur application comme medicaments
HU172649B (hu) * 1975-04-24 1978-11-28 Gyogyszerkutato Intezet Sposob poluchenija novykh biologicheski aktivnykh lizergamidov
GB1549829A (en) * 1976-05-26 1979-08-08 Farmaceutici Italia 10'-methoxy-1',6'-dimethylergoline-8'-beta-methyl-amino(or thio)-pyrazines
GB1555751A (en) * 1977-02-02 1979-11-14 Farmaceutici Italia Ergoline deritatives
AU553809B2 (en) * 1981-07-21 1986-07-31 Farmitalia Carlo Erba S.P.A. Ergoline derivatives

Also Published As

Publication number Publication date
IT1189409B (it) 1988-02-04
HU187798B (en) 1986-02-28
IL67156A (en) 1985-05-31
PH20595A (en) 1987-02-24
DE3239788A1 (de) 1983-05-11
FI71735B (fi) 1986-10-31
FR2516084A1 (fr) 1983-05-13
IL67156A0 (en) 1983-03-31
SE8206217D0 (sv) 1982-11-02
ZA828104B (en) 1984-06-27
FI823694L (fi) 1983-05-05
JPS5885885A (ja) 1983-05-23
DK486582A (da) 1983-05-05
FR2516084B1 (fr) 1985-01-11
IE822627L (en) 1983-05-04
PT75773A (en) 1982-12-01
SE8206217L (sv) 1983-05-05
IE54122B1 (en) 1989-06-21
NL8204213A (nl) 1983-06-01
BE894844A (fr) 1983-04-28
MY8600310A (en) 1986-12-31
AU561250B2 (en) 1987-05-07
KE3797A (en) 1988-03-11
FI71735C (fi) 1987-02-09
CH653333A5 (de) 1985-12-31
AT382374B (de) 1987-02-25
SE450122B (sv) 1987-06-09
ATA400482A (de) 1986-07-15
IT8249418A0 (it) 1982-11-03
NZ202363A (en) 1985-12-13
US4783464A (en) 1988-11-08
FI823694A0 (fi) 1982-10-28
JPH0366306B2 (fr) 1991-10-16
ES8403898A1 (es) 1984-04-01
CA1193249A (fr) 1985-09-10
GB2108502A (en) 1983-05-18
AU9010782A (en) 1983-05-12
GB2108502B (en) 1985-07-10
HK37188A (en) 1988-05-27
ES517082A0 (es) 1984-04-01

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