CY1654A - Process for resolution and race mization of amines with acidic alpha-hydrogens - Google Patents

Process for resolution and race mization of amines with acidic alpha-hydrogens

Info

Publication number
CY1654A
CY1654A CY165493A CY165493A CY1654A CY 1654 A CY1654 A CY 1654A CY 165493 A CY165493 A CY 165493A CY 165493 A CY165493 A CY 165493A CY 1654 A CY1654 A CY 1654A
Authority
CY
Cyprus
Prior art keywords
mization
hydrogens
race
amines
resolution
Prior art date
Application number
CY165493A
Other languages
English (en)
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of CY1654A publication Critical patent/CY1654A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CY165493A 1986-07-14 1993-05-14 Process for resolution and race mization of amines with acidic alpha-hydrogens CY1654A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US88504786A 1986-07-14 1986-07-14

Publications (1)

Publication Number Publication Date
CY1654A true CY1654A (en) 1993-05-14

Family

ID=25386005

Family Applications (1)

Application Number Title Priority Date Filing Date
CY165493A CY1654A (en) 1986-07-14 1993-05-14 Process for resolution and race mization of amines with acidic alpha-hydrogens

Country Status (7)

Country Link
EP (1) EP0253571B1 (fr)
JP (1) JPS6323824A (fr)
CA (1) CA1310316C (fr)
CY (1) CY1654A (fr)
DE (1) DE3760472D1 (fr)
HK (1) HK59292A (fr)
SG (1) SG58192G (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4859771A (en) * 1986-07-14 1989-08-22 Merck & Co., Inc. Process for resolution and racemization of amines with acidic α-hydrogens
US5969186A (en) * 1996-03-28 1999-10-19 Nagase & Company, Ltd. Process for racemizing of optically active amines
JPH10143660A (ja) * 1996-11-11 1998-05-29 Hitachi Ltd 欠陥判定処理方法およびその装置
WO2005103005A1 (fr) * 2004-04-26 2005-11-03 Astellas Pharma Inc. PROCÉDÉ SERVANT À PRODUIRE SÉLECTIVEMENT UN ISOMÈRE OPTIQUEMENT ACTIF DE LA β-PYRIDYLALANINE
US12503449B2 (en) * 2020-02-16 2025-12-23 Immunome, Inc. Methods of preparing chiral benzodiazepinone derivatives

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH601263A5 (fr) * 1974-10-21 1978-06-30 Hoffmann La Roche
NL7602544A (nl) * 1976-03-11 1977-09-13 Stamicarbon Werkwijze voor de bereiding van optisch aktief fenylglycine.
NL188407C (nl) * 1977-10-18 1992-06-16 Kessels Gerard Werkwijze voor de bereiding van d(-)-alfa-fenylglycine.
JPS5686138A (en) * 1979-12-18 1981-07-13 Hiroyuki Nohira Optical resolution of (+-)phenylglycine and (+-)camphorsulfonic acid
JPS59170059A (ja) * 1983-03-16 1984-09-26 Tanabe Seiyaku Co Ltd 光学活性α―アミノ酸の製法
CA1332410C (fr) * 1984-06-26 1994-10-11 Roger M. Freidinger Analogues de benzodiazepines

Also Published As

Publication number Publication date
EP0253571B1 (fr) 1989-08-23
SG58192G (en) 1992-07-24
HK59292A (en) 1992-08-14
JPS6323824A (ja) 1988-02-01
CA1310316C (fr) 1992-11-17
DE3760472D1 (en) 1989-09-28
EP0253571A1 (fr) 1988-01-20

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