CY2471B1 - Fungal protease. - Google Patents

Fungal protease.

Info

Publication number
CY2471B1
CY2471B1 CY0400062A CY0400062A CY2471B1 CY 2471 B1 CY2471 B1 CY 2471B1 CY 0400062 A CY0400062 A CY 0400062A CY 0400062 A CY0400062 A CY 0400062A CY 2471 B1 CY2471 B1 CY 2471B1
Authority
CY
Cyprus
Prior art keywords
aspergillus
protease
preparation
mutant strain
aspartic
Prior art date
Application number
CY0400062A
Other languages
English (en)
Inventor
Frank Buxton
Gabor Jarai
Jacob Visser
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of CY2471B1 publication Critical patent/CY2471B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
    • C12N9/62—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi from Aspergillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Detergent Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CY0400062A 1993-11-03 2004-08-10 Fungal protease. CY2471B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP93810764 1993-11-03

Publications (1)

Publication Number Publication Date
CY2471B1 true CY2471B1 (en) 2005-06-03

Family

ID=8215057

Family Applications (1)

Application Number Title Priority Date Filing Date
CY0400062A CY2471B1 (en) 1993-11-03 2004-08-10 Fungal protease.

Country Status (18)

Country Link
US (2) US5674728A (fr)
EP (1) EP0655497B1 (fr)
JP (1) JP3727678B2 (fr)
KR (1) KR100378507B1 (fr)
AT (1) ATE235556T1 (fr)
AU (1) AU688379B2 (fr)
CA (1) CA2134863C (fr)
CY (1) CY2471B1 (fr)
DE (1) DE69432336T2 (fr)
DK (1) DK0655497T3 (fr)
ES (1) ES2196019T3 (fr)
FI (1) FI119060B (fr)
HU (1) HU220360B (fr)
IL (2) IL168245A (fr)
NO (1) NO315330B1 (fr)
NZ (1) NZ264839A (fr)
PT (1) PT655497E (fr)
ZA (1) ZA948619B (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1203627A (zh) * 1995-12-07 1998-12-30 诺沃挪第克公司 酶活性的选择性灭活
CN1160465C (zh) * 1995-12-15 2004-08-04 诺沃奇梅兹有限公司 其中areA、pepC和/或pepE基因已被灭活的真菌
JP2000511429A (ja) * 1996-06-05 2000-09-05 ギスト ブロカデス ベスローテン フェンノートシャップ 真菌メタロプロテアーゼ遺伝子
AU4200897A (en) * 1996-09-19 1998-04-14 Novo Nordisk A/S Novel host cells and methods of producing proteins
KR100880087B1 (ko) * 2001-02-23 2009-01-23 디에스엠 아이피 어셋츠 비.브이. 신규 단백질 분해효소를 암호화하는 신규 유전자
AU2006202723B2 (en) * 2001-02-23 2008-06-26 Dsm Ip Assets B.V. Novel genes encoding novel proteolytic enzymes
US7323327B2 (en) * 2001-02-23 2008-01-29 Dsm Ip Assets B.V. Genes encoding novel proteolytic enzymes
US20090253173A1 (en) * 2008-04-08 2009-10-08 Danisco Us Inc., Genencor Division Filamentous fungi with inactivated protease genes for altered protein production
FI121712B (fi) * 2009-04-30 2011-03-15 Ab Enzymes Oy Uusi sieniperäinen proteaasi ja sen käyttö
EP2800809B1 (fr) 2012-01-05 2018-03-07 Glykos Finland Oy Cellules fongiques filamenteuses déficientes en protéase et procédés d'utilisation de celles-ci
DK2852610T3 (en) 2012-05-23 2018-09-03 Glykos Finland Oy PRODUCTION OF FUCOSYLED GLYCOPROTEIN
DK3019602T3 (en) 2013-07-10 2018-11-12 Glykos Finland Oy MULTIPLE PROTEASE-DEFECTED FILAMENTARY FUNGAL CELLS AND PROCEDURES FOR USE THEREOF
AU2015293949B2 (en) 2014-07-21 2019-07-25 Teknologian Tutkimuskeskus Vtt Oy Production of glycoproteins with mammalian-like N-glycans in filamentous fungi
CN106222096B (zh) * 2016-08-18 2018-02-23 滨州学院 一株塔宾曲霉菌ct1及其在盐碱地解磷方面的应用
CN121022803B (zh) * 2025-10-29 2026-01-09 内蒙古科为博生物科技有限公司 一种耐热性提高的酸性蛋白酶突变体PepA4及其应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8415186D0 (en) * 1984-06-14 1984-07-18 Ciba Geigy Ag Polypeptides
US4885249A (en) * 1984-12-05 1989-12-05 Allelix, Inc. Aspergillus niger transformation system
GB8521496D0 (en) * 1985-08-29 1985-10-02 Ciba Geigy Ag Repressible yeast promoters
GB8702475D0 (en) * 1987-02-04 1987-03-11 Ciba Geigy Ag Expression system
WO1988007076A1 (fr) * 1987-03-12 1988-09-22 Genex Corporation Production d'analogues de proteines precurseur bioadhesifs par des organismes mis au point genetiquement
US4871824A (en) * 1987-03-13 1989-10-03 Minnesota Mining And Manufacturing Company Variably crosslinked polymeric supports
US5252726A (en) * 1987-09-04 1993-10-12 Novo Nordisk A/S Promoters for use in aspergillus
CA1333777C (fr) * 1988-07-01 1995-01-03 Randy M. Berka Champignons filamenteux deficients en proteinase aspartique
EP0353188B2 (fr) * 1988-07-28 2002-03-06 Novartis AG Système d'expression
EP0421919A3 (en) * 1989-09-02 1992-04-15 Ciba-Geigy Ag Polygalacturonase encoding fungal expression system
FI103206B (fi) * 1990-01-29 1999-05-14 Novartis Ag Uusi ilmentämisjärjestelmä sieniä varten
JPH06506117A (ja) * 1991-04-01 1994-07-14 メルク　エンド　カンパニー　インコーポレーテッド ピキア（Ｐｉｃｈｉａ）蛋白質分解活性に影響する遺伝子およびその使用
DK47493D0 (da) * 1993-04-27 1993-04-27 Novo Nordisk As Fremgangsmaade til fremstilling af ost

Also Published As

Publication number Publication date
EP0655497B1 (fr) 2003-03-26
NO315330B1 (no) 2003-08-18
FI945163L (fi) 1995-05-04
ZA948619B (en) 1995-06-27
HU9403136D0 (en) 1994-12-28
IL168245A (en) 2009-12-24
IL111482A (en) 2005-08-31
HU220360B (hu) 2001-12-28
EP0655497A2 (fr) 1995-05-31
KR100378507B1 (ko) 2003-09-19
EP0655497A3 (fr) 1997-05-07
US5756338A (en) 1998-05-26
FI119060B (fi) 2008-07-15
FI945163A0 (fi) 1994-11-02
DE69432336D1 (de) 2003-04-30
CA2134863C (fr) 2008-12-30
JPH07213286A (ja) 1995-08-15
AU688379B2 (en) 1998-03-12
US5674728A (en) 1997-10-07
DE69432336T2 (de) 2003-12-04
JP3727678B2 (ja) 2005-12-14
CA2134863A1 (fr) 1995-05-04
KR950014309A (ko) 1995-06-15
DK0655497T3 (da) 2003-07-21
ES2196019T3 (es) 2003-12-16
PT655497E (pt) 2003-07-31
ATE235556T1 (de) 2003-04-15
NZ264839A (en) 1996-03-26
NO944181D0 (no) 1994-11-02
HUT69954A (en) 1995-09-28
IL111482A0 (en) 1995-01-24
NO944181L (no) 1995-05-04
AU7751494A (en) 1995-05-18

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