CZ9802013A3 - Deriváty OB proteinu, chimerní OB polypeptidy, prostředky pro léčbu obezity a dalších fyziologických stavů a způsob léčení těmito prostředky, kódující sekvence pro OB protein, expresní vektor nesoucí tuto sekvenci, buňky transformované tímto vektorem a způsob jejich kultivace, a způsob navození růstu buněk s pomocí OB proteinu - Google Patents

Deriváty OB proteinu, chimerní OB polypeptidy, prostředky pro léčbu obezity a dalších fyziologických stavů a způsob léčení těmito prostředky, kódující sekvence pro OB protein, expresní vektor nesoucí tuto sekvenci, buňky transformované tímto vektorem a způsob jejich kultivace, a způsob navození růstu buněk s pomocí OB proteinu Download PDF

Info

Publication number: CZ9802013A3
Authority: CZ; Czechia
Prior art keywords: protein; sequence; immunoglobulin; cells; native
Prior art date: 1995-12-27

Application number

CZ982013A

Other languages

Czech (cs)

English (en)

Inventor

Sauvage Frederic J. De

Nancy Levin

Richard L. Vandlen

Original Assignee

Genentech, Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-12-27

Filing date

1996-12-19

Publication date

1998-09-16

1996-12-19 Application filed by Genentech, Inc. filed Critical Genentech, Inc.

1998-09-16 Publication of CZ9802013A3 publication Critical patent/CZ9802013A3/cs

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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/5759—Products of obesity genes, e.g. leptin, obese (OB), tub, fat
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide

Landscapes

Health & Medical Sciences (AREA)
Diabetes (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Obesity (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Endocrinology (AREA)
Hematology (AREA)
Child & Adolescent Psychology (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Emergency Medicine (AREA)
Toxicology (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

CZ982013A 1995-12-27 1996-12-19 Deriváty OB proteinu, chimerní OB polypeptidy, prostředky pro léčbu obezity a dalších fyziologických stavů a způsob léčení těmito prostředky, kódující sekvence pro OB protein, expresní vektor nesoucí tuto sekvenci, buňky transformované tímto vektorem a způsob jejich kultivace, a způsob navození růstu buněk s pomocí OB proteinu CZ9802013A3 (cs)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US57949495A	1995-12-27	1995-12-27
US66718496A	1996-06-20	1996-06-20
PCT/US1996/020718 WO1997024440A1 (en)	1995-12-27	1996-12-19	Ob protein derivatives having prolonged half-life

Publications (1)

Publication Number	Publication Date
CZ9802013A3 true CZ9802013A3 (cs)	1998-09-16

Family

ID=27077779

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CZ982013A CZ9802013A3 (cs)	1995-12-27	1996-12-19	Deriváty OB proteinu, chimerní OB polypeptidy, prostředky pro léčbu obezity a dalších fyziologických stavů a způsob léčení těmito prostředky, kódující sekvence pro OB protein, expresní vektor nesoucí tuto sekvenci, buňky transformované tímto vektorem a způsob jejich kultivace, a způsob navození růstu buněk s pomocí OB proteinu

Country Status (14)

Country	Link
EP (1)	EP0870026B1 (2)
JP (1)	JP4037905B2 (2)
CN (1)	CN1154726C (2)
AT (1)	ATE267255T1 (2)
AU (1)	AU1520097A (2)
BR (1)	BR9612359A (2)
CA (1)	CA2238307A1 (2)
CZ (1)	CZ9802013A3 (2)
DE (1)	DE69632546T2 (2)
IL (1)	IL124831A0 (2)
MX (1)	MX9804687A (2)
NZ (1)	NZ326592A (2)
RU (1)	RU2178307C2 (2)
WO (1)	WO1997024440A1 (2)

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1996
- 1996-12-19 AU AU15200/97A patent/AU1520097A/en not_active Abandoned
- 1996-12-19 EP EP96945295A patent/EP0870026B1/en not_active Expired - Lifetime
- 1996-12-19 CA CA002238307A patent/CA2238307A1/en not_active Abandoned
- 1996-12-19 BR BR9612359A patent/BR9612359A/pt not_active Application Discontinuation
- 1996-12-19 IL IL12483196A patent/IL124831A0/xx unknown
- 1996-12-19 CZ CZ982013A patent/CZ9802013A3/cs unknown
- 1996-12-19 RU RU98113706/14A patent/RU2178307C2/ru active
- 1996-12-19 CN CNB961992654A patent/CN1154726C/zh not_active Expired - Lifetime
- 1996-12-19 AT AT96945295T patent/ATE267255T1/de active
- 1996-12-19 WO PCT/US1996/020718 patent/WO1997024440A1/en not_active Ceased
- 1996-12-19 DE DE69632546T patent/DE69632546T2/de not_active Expired - Lifetime
- 1996-12-19 NZ NZ326592A patent/NZ326592A/en not_active IP Right Cessation
- 1996-12-19 JP JP52455197A patent/JP4037905B2/ja not_active Expired - Lifetime
1998
- 1998-06-11 MX MX9804687A patent/MX9804687A/es active IP Right Grant

Also Published As

Publication number	Publication date
ATE267255T1 (de)	2004-06-15
RU2178307C2 (ru)	2002-01-20
AU1520097A (en)	1997-07-28
CN1154726C (zh)	2004-06-23
EP0870026B1 (en)	2004-05-19
JP2000504210A (ja)	2000-04-11
DE69632546D1 (de)	2004-06-24
DE69632546T2 (de)	2005-06-30
CA2238307A1 (en)	1997-07-10
CN1205738A (zh)	1999-01-20
NZ326592A (en)	2001-05-25
EP0870026A1 (en)	1998-10-14
MX9804687A (es)	1998-10-31
IL124831A0 (en)	1999-01-26
JP4037905B2 (ja)	2008-01-23
WO1997024440A1 (en)	1997-07-10
BR9612359A (pt)	1999-07-13

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