DD202709A5 - Verfahren zur herstellung von beta-cyclo-substituierten ethylaminen - Google Patents

Verfahren zur herstellung von beta-cyclo-substituierten ethylaminen Download PDF

Info

Publication number
DD202709A5
DD202709A5 DD82241197A DD24119782A DD202709A5 DD 202709 A5 DD202709 A5 DD 202709A5 DD 82241197 A DD82241197 A DD 82241197A DD 24119782 A DD24119782 A DD 24119782A DD 202709 A5 DD202709 A5 DD 202709A5
Authority
DD
German Democratic Republic
Prior art keywords
ppm
formula
item
derivative
compound
Prior art date
Application number
DD82241197A
Other languages
German (de)
English (en)
Inventor
Isaac Chekroun
Alain Heymes
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of DD202709A5 publication Critical patent/DD202709A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms
    • C07F9/655345—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a five-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/68—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/28—Halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/22—Amides of acids of phosphorus
    • C07F9/24—Esteramides
    • C07F9/2454—Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/2462—Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic of unsaturated acyclic amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/22—Amides of acids of phosphorus
    • C07F9/24—Esteramides
    • C07F9/2454—Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/2475—Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic of aralkylamines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576—Six-membered rings
    • C07F9/58—Pyridine rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/65515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Furan Compounds (AREA)
  • Pyridine Compounds (AREA)
DD82241197A 1981-06-30 1982-06-29 Verfahren zur herstellung von beta-cyclo-substituierten ethylaminen DD202709A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8113065A FR2508442A1 (fr) 1981-06-30 1981-06-30 Procede de preparation d'ethylamines b-cyclo-substituees et produits ainsi obtenus

Publications (1)

Publication Number Publication Date
DD202709A5 true DD202709A5 (de) 1983-09-28

Family

ID=9260132

Family Applications (1)

Application Number Title Priority Date Filing Date
DD82241197A DD202709A5 (de) 1981-06-30 1982-06-29 Verfahren zur herstellung von beta-cyclo-substituierten ethylaminen

Country Status (25)

Country Link
US (1) US4493931A (cs)
EP (1) EP0069622B1 (cs)
JP (1) JPS5813547A (cs)
KR (1) KR840000524A (cs)
AR (1) AR231433A1 (cs)
AT (1) ATE15650T1 (cs)
AU (1) AU567282B2 (cs)
CA (1) CA1184918A (cs)
CS (1) CS238628B2 (cs)
DD (1) DD202709A5 (cs)
DE (1) DE3266363D1 (cs)
DK (1) DK294682A (cs)
ES (1) ES8305303A1 (cs)
FI (1) FI71550C (cs)
FR (1) FR2508442A1 (cs)
GR (1) GR77204B (cs)
HU (1) HU189597B (cs)
IE (1) IE53257B1 (cs)
IL (1) IL65983A (cs)
NO (1) NO153133C (cs)
NZ (1) NZ200855A (cs)
PT (1) PT75155B (cs)
SU (1) SU1147249A3 (cs)
YU (1) YU143182A (cs)
ZA (1) ZA824617B (cs)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0762877T3 (da) * 1994-06-03 2001-07-16 Thejmde Trust Meta-substituerede arylalkylaminer og terapeutiske og diagnostiske anvendelser deraf
AU5239899A (en) * 1998-07-31 2000-02-21 Eli Lilly And Company Amidophosphate derivatives
JP2008509909A (ja) * 2004-08-11 2008-04-03 ウィリアムスバーグ・ホールディングス・エルエルシー 心毒性のない医薬化合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2983729A (en) * 1958-04-30 1961-05-09 Monsanto Chemicals Preparation of 5-halothienyl amines
FR2215948B1 (cs) * 1973-02-01 1976-05-14 Centre Etd Ind Pharma
FR2345150A2 (fr) * 1975-08-06 1977-10-21 Centre Etd Ind Pharma Nouveaux derives de la thienopyridine, et leur application

Also Published As

Publication number Publication date
PT75155A (fr) 1982-07-01
EP0069622A1 (fr) 1983-01-12
AU8475182A (en) 1983-01-06
GR77204B (cs) 1984-09-11
US4493931A (en) 1985-01-15
NO822227L (no) 1983-01-03
NO153133C (no) 1986-01-22
KR840000524A (ko) 1984-02-25
ES514101A0 (es) 1983-04-01
IL65983A0 (en) 1982-09-30
FI71550B (fi) 1986-10-10
EP0069622B1 (fr) 1985-09-18
AR231433A1 (es) 1984-11-30
IE821313L (en) 1982-12-30
AU567282B2 (en) 1987-11-19
NZ200855A (en) 1985-08-30
CA1184918A (en) 1985-04-02
DK294682A (da) 1982-12-31
FR2508442B1 (cs) 1984-03-09
ZA824617B (en) 1983-04-27
IL65983A (en) 1985-06-30
NO153133B (no) 1985-10-14
FI822314L (fi) 1982-12-31
DE3266363D1 (en) 1985-10-24
PT75155B (fr) 1984-05-29
ATE15650T1 (de) 1985-10-15
JPS5813547A (ja) 1983-01-26
ES8305303A1 (es) 1983-04-01
FR2508442A1 (fr) 1982-12-31
FI822314A0 (fi) 1982-06-29
YU143182A (en) 1985-03-20
FI71550C (fi) 1987-01-19
HU189597B (en) 1986-07-28
CS238628B2 (en) 1985-12-16
SU1147249A3 (ru) 1985-03-23
IE53257B1 (en) 1988-09-28

Similar Documents

Publication Publication Date Title
IL275584B1 (en) A process for separating a serial mixture of nicotine
JPH01301687A (ja) 置換プロパンホスフィン酸化合物
DE3817956A1 (de) Verfahren zur herstellung phosphorhaltiger l-aminosaeuren sowie ihrer ester und n-derivate
DE1939809C3 (cs)
DE112011104615B4 (de) Organoborverbindung und Verfahren zum Herstellen derselben
DD156369A5 (de) Herstellung von rechtsdrehenden 5-aryl-2,3,4,4a,5,9b-hexahydro-1h-pyrido[4,3b]-indolen
SU1148563A3 (ru) Способ получени производных 2-(тиенил-2)- или 2-(тиенил-3) этиламина
EP0222163B1 (de) Verfahren zur Herstellung von gamma-Butyrolactamen
DE68902840T2 (de) Phenol-alkyl- oder -benzylether, verfahren zu ihrer herstellung und ihre therapeutische verwendung.
CH417574A (de) Verfahren zur Herstellung therapeutisch wirksamer Dibenzocycloheptanderivate
DE3153690C2 (cs)
DD202712A5 (de) Verfahren zur herstellung von (thienyl-2)-und (thienyl-3)-2-aethylaminderivaten
DD243491A5 (de) Verfahren zur herstellung neuer 3-phenyl-2-propanamin-derivate
CH653028A5 (de) Benzthiophenallylamin-verbindungen und verfahren zu ihrer herstellung.
DD202710A5 (de) Verfahren zur herstellung von (thienyl-2)- und (thienyl-3)-2-aethylamin-derivaten
DE3779525T2 (de) 5-aminomethyl-2-oxazolidinon-derivate, ihre herstellung und ihre anwendung in der heilkunde.
DD298931A5 (de) Verfahren zur herstellung ungesaettigter aminodicarbonsaeurederivate
EP0420806A1 (de) Phosphonsäure, Verfahren zur Herstellung und Verwendung als Arzneimittelwirkstoff
AT395852B (de) Imidazolyl-methyl-tetrahydrothiophenderivate
US4493931A (en) Process for the preparation of β-cyclo-substituted ethylamines
DE966534C (de) Verfahren zur Herstellung von basisch substituierten Pyridinverbindungen
EP0005186B1 (de) 3-Alkyl-5-(2-hydroxy-styryl)-isoxazole und Verfahren zu ihrer Herstellung
AT371445B (de) Verfahren zur herstellung von neuen cis-4a-phenyl-isochinolinderivaten und ihren saeureadditionssalzen
WO1995000522A1 (de) Phosphonobernsteinsäurederivate und ihre verwendung als arzneimittel
AT377518B (de) Verfahren zur herstellung von neuen derivaten des (alkyl-(chinolyl))-piperidin und ihren salzen