DD209461A5 - Verfahren zur herstellung von 4,5-dihydro-3(2h)-pyridazinonen - Google Patents

Verfahren zur herstellung von 4,5-dihydro-3(2h)-pyridazinonen Download PDF

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Publication number
DD209461A5
DD209461A5 DD82237856A DD23785682A DD209461A5 DD 209461 A5 DD209461 A5 DD 209461A5 DD 82237856 A DD82237856 A DD 82237856A DD 23785682 A DD23785682 A DD 23785682A DD 209461 A5 DD209461 A5 DD 209461A5
Authority
DD
German Democratic Republic
Prior art keywords
formula
compound
group
acid
compounds
Prior art date
Application number
DD82237856A
Other languages
German (de)
English (en)
Inventor
Richard Goeschke
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DD209461A5 publication Critical patent/DD209461A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Curing Cements, Concrete, And Artificial Stone (AREA)
  • Chemical And Physical Treatments For Wood And The Like (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Treating Waste Gases (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
DD82237856A 1981-03-04 1982-03-03 Verfahren zur herstellung von 4,5-dihydro-3(2h)-pyridazinonen DD209461A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH144381 1981-03-04

Publications (1)

Publication Number Publication Date
DD209461A5 true DD209461A5 (de) 1984-05-09

Family

ID=4210578

Family Applications (1)

Application Number Title Priority Date Filing Date
DD82237856A DD209461A5 (de) 1981-03-04 1982-03-03 Verfahren zur herstellung von 4,5-dihydro-3(2h)-pyridazinonen

Country Status (24)

Country Link
US (3) US4613599A (fr)
EP (1) EP0059688B1 (fr)
JP (1) JPS57158762A (fr)
AT (1) ATE13294T1 (fr)
AU (1) AU558039B2 (fr)
CA (1) CA1180703A (fr)
CY (1) CY1396A (fr)
DD (1) DD209461A5 (fr)
DE (1) DE3263497D1 (fr)
DK (1) DK148772C (fr)
ES (4) ES8308561A1 (fr)
FI (1) FI72718C (fr)
GB (1) GB2094302B (fr)
GR (1) GR81397B (fr)
HK (1) HK87687A (fr)
HU (1) HU191083B (fr)
IE (1) IE52672B1 (fr)
IL (1) IL65161A (fr)
MY (1) MY8700736A (fr)
NO (1) NO158135C (fr)
NZ (1) NZ199892A (fr)
PT (1) PT74520B (fr)
SG (1) SG59587G (fr)
ZA (1) ZA821397B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4734415A (en) * 1982-08-13 1988-03-29 Warner-Lambert Company Substituted 4,5-dihydro-6-(substituted)-phenyl-3(2H)-pyridazinones and 6-(substituted) phenyl-3(2H)-pyridazinones
GB8400863D0 (en) * 1984-01-13 1984-02-15 Smith Kline French Lab Chemical compounds
GB8426804D0 (en) * 1984-10-23 1984-11-28 Ciba Geigy Ag Pyridazinones preparations
JPS61158969A (ja) * 1984-12-24 1986-07-18 ワーナー‐ランバート・コンパニー ４，５‐ジヒドロ‐４，４‐ジアルキル‐６‐（置換）フエニル‐３（２ｈ）‐ピリダジノン類
IL79280A (en) * 1985-07-05 1990-07-12 Smith Kline French Lab 4-(6-oxo-dihydro or tetrahydropyridazin-3-yl)benzene derivatives,their preparation and pharmaceutical compositions containing them
US4970210A (en) * 1987-07-17 1990-11-13 Abbott Laboratories Triazinone lipoxygenase compounds
DE3735207A1 (de) * 1987-10-17 1989-04-27 Basf Ag Mittel auf der basis von phenylpyridazinon-derivaten zur wachstumsfoerderung und fettreduktion bei tieren
WO2014164704A2 (fr) * 2013-03-11 2014-10-09 The Broad Institute, Inc. Composés et compositions utilisables en vue du traitement du cancer
JOP20200024A1 (ar) 2017-08-04 2020-02-02 Bayer Ag مركبات ثنائي هيدروكساديازينون
EP3661917B1 (fr) 2017-08-04 2022-05-11 Bayer Aktiengesellschaft Dérivés 6-((3-trifluorométhyl)phényl)-4,5-dihydropyridazin-3(2h)-one en tant qu'inhibiteurs de pde3a et pde3b pour le traitement du cancer
AU2020215088A1 (en) 2019-02-01 2021-07-22 Bayer Aktiengesellschaft 1,2,4-triazin-3(2H)-one compounds for the treatment of hyperproliferative diseases

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1488330A (en) * 1923-02-01 1924-03-25 Everitt James Clothes-hanging bar formed of hinged-together members
IL37788A0 (en) * 1970-10-09 1971-12-29 American Cyanamid Co New pyridazinone compounds,their preparation and pharmaceutical compositions containing them
US3975388A (en) * 1971-02-22 1976-08-17 Bdh Pharmaceuticals Limited Pyridazinones
GB1383906A (en) * 1971-02-22 1974-02-12 Bdh Pharmaceuticals Ltd Pyridazinones
GB1488330A (en) * 1973-12-19 1977-10-12 Smith Kline French Lab Dihydropyridazinones
DE2854191A1 (de) * 1978-12-15 1980-07-03 Basf Ag Dihydropyridazinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende therapeutische mittel

Also Published As

Publication number Publication date
FI72718B (fi) 1987-03-31
CA1180703A (fr) 1985-01-08
ES510055A0 (es) 1983-09-16
US4704391A (en) 1987-11-03
AU8106582A (en) 1982-09-09
HU191083B (en) 1987-01-28
FI72718C (fi) 1987-07-10
NO158135B (no) 1988-04-11
MY8700736A (en) 1987-12-31
NZ199892A (en) 1985-05-31
IL65161A (en) 1985-05-31
JPS57158762A (en) 1982-09-30
AU558039B2 (en) 1987-01-15
NO820670L (no) 1982-09-06
EP0059688B1 (fr) 1985-05-15
US4654340A (en) 1987-03-31
ES520023A0 (es) 1984-04-01
IE820478L (en) 1982-09-04
IE52672B1 (en) 1988-01-20
GB2094302B (en) 1984-10-10
ES520024A0 (es) 1984-04-01
ZA821397B (en) 1983-01-26
PT74520A (de) 1982-04-01
ES8308561A1 (es) 1983-09-16
DK148772C (da) 1986-05-12
DE3263497D1 (en) 1985-06-20
NO158135C (no) 1988-07-20
CY1396A (en) 1987-12-18
DK91782A (da) 1982-09-05
GR81397B (fr) 1984-12-11
GB2094302A (en) 1982-09-15
DK148772B (da) 1985-09-23
HK87687A (en) 1987-12-04
ES8403893A1 (es) 1984-04-01
ATE13294T1 (de) 1985-06-15
EP0059688A1 (fr) 1982-09-08
ES8403892A1 (es) 1984-04-01
PT74520B (de) 1984-11-19
IL65161A0 (en) 1982-05-31
FI820699L (fi) 1982-09-05
US4613599A (en) 1986-09-23
SG59587G (en) 1987-10-23
ES8403894A1 (es) 1984-04-01
ES520022A0 (es) 1984-04-01

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